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Confidential, for Use of the Commission Only (as permitted by Rule14a-6(e)(2))
x
Definitive Proxy Statement
¨
Definitive Additional Materials
¨
Soliciting Material under 240.14a-12
AKARI THERAPEUTICS, PLC
(Name of Registrant as Specified in its Charter)
N/A
(Name of Person(s)Filing Proxy Statement, if other
than the Registrant)
Payment of Filing Fee (Check all boxes that apply):
x
No fee required
¨
Fee paid previously with preliminary materials
¨
Fee computed on table in exhibit required by Item 25(b)per Exchange Act Rules14a-6(i)(1)and 0-11
AKARI THERAPEUTICS, PLC
22 Boston Wharf Road, FL 7
Boston, Massachusetts 02210
June3, 2024
2024 Annual General Meeting of Akari Therapeutics, Plc (the Meeting
or AGM)
This letter, the notice of the Meeting set out
in this document (the Notice) and associated materials for the Meeting are being sent to you because, as of May31,
2024 (being the latest practicable date before the circulation of this document), you are registered as a holder of ordinary shares in
the register of members of Akari Therapeutics, Plc (the Company). However, this letter, the Notice and associated materials
will also be available to holders of our American Depositary Shares (ADS) and contain information relevant to holders of
ADSs.
Our Meeting will take place at 2:00 p.m., London
time, on June27, 2024, at 75/76 Wimpole Street, London, W1G 9RT. The Notice is set out in this document, and it contains the resolutions
to be proposed at the Meeting (the Resolutions).
For the purposes of the Meeting, a quorum will
be obtained by two or more qualifying persons present at a meeting and between them holding (or being the proxy or corporate representative
of the holders of) at least 33
1
3
% of the Companys share capital
(excluding any shares held as treasury shares) entitled to attend and vote on the business to be transacted at the Meeting. A qualifying
person is an individual who is a member, a person authorized to act as the representative of a member (being a corporation) in
relation to the Meeting, or a person appointed as proxy of a member in relation to the Meeting.
Action to be taken by holders of ordinary shares in the Company
If you are a holder of ADSs, please ignore this
section and refer instead to the section below -
Holders of American Depositary Shares
. If you are a holder of ordinary
shares in the register of members of the Company, please vote on the Resolutions by appointing a proxy. A form of proxy for use at the
Meeting is enclosed.
You are encouraged to appoint the Chairman of the Meeting as your proxy. If you appoint any person other than
the Chairman of the Meeting as your proxy, that person may not be allowed to attend the Meeting.
You are advised to complete and return the form
of proxy in accordance with the instructions printed on it and so as to arrive at the Companys registrar, Equiniti Limited, at
Aspect House, Spencer Road, Lancing, BN99 6DA (Equiniti Group), England as soon as possible but in any event by no later
than 2:00 pm London time (9:00 am Eastern time) on June25, 2024.
In order to attend and vote at the Meeting as
an ordinary shareholder, you must continue to be registered as a holder of ordinary shares in the Companys register of members
as of
6:30 pm London time (1:30 pm Eastern time) on June25, 2024
.
Therefore, if you sell or transfer your ordinary
shares in the Company on or prior to June25, 2024, your form of proxy can no longer be used and if submitted (whether before or
after you sell or transfer your ordinary shares) will be treated as invalid. Please pass this document to the person who arranged the
sale or transfer for delivery to the purchaser or transferee. The purchaser or transferee should contact Joe Carroll, Company Secretary,
by telephone at +1 (929) 274-7511, to request a new form of proxy for its use.
Should you elect to convert your holding of ordinary
shares in the capital stock of the Company into an interest in the capital of the Company represented by ADSs before the Meeting, you
will cease to be a holder of ordinary shares in your own name and will not be entitled to vote at the Meeting as an ordinary shareholder.
You will also not be able to use the enclosed form of proxy. However, you may be able to exercise your vote as a holder of an interest
in the capital of the Company represented by American Depositary Shares. Please refer to the next section -
Holders of American
Depositary Shares
.
Holders of American Depositary Shares
In order to exercise your vote as a holder of
an interest in the capital of the Company represented by ADSs, you or your bank, broker or nominee must be registered as a holder of ADSs
in the ADS register maintained by our depositary, Deutsche Bank Trust Company Americas (Deutsche Bank) as of 5:00 p.m.Eastern
Time on Friday, May24, 2024 (the record date for ADS holders). If you hold ADSs through a bank, broker or nominee on May24,
2024, the Meeting documentation, including the ADS proxy card, will be sent to your broker who should forward the materials to you. Please
reach out to your broker to provide your voting instructions.
Please note that ADS proxy cards submitted by
ADS holders must be received by Deutsche Bank
no later than
1:00
p.m.Eastern Time on June17, 2024
.
Contacts for ADS holders
If you have queries about how you can deliver
voting instructions, please contact Deutsche Bank c/o Equiniti Trust Company by telephone: +1 (800) 937-5449 (toll free within the United
States) or +1 (718) 921-8137 (for international callers) or by email at adr@equiniti.com or by mail at Deutsche Bank Trust Company Americas,
c/o Equiniti Trust Company, Peck Slip Station PO Box 2050 New York, NY 10272-2050.
If at any point you require guidance, please contact
Joe Carroll, Company Secretary, by telephone at +1 (929) 274-7511.
Recommendation
You will find an explanatory note in relation
to each of the Resolutions in the attached proxy statement (the Proxy Statement). Your directors consider that each Resolution
is in the best interests of the Company and its shareholders as a whole and is likely to promote the success of the Company. Accordingly,
your directors unanimously recommend that you vote in favor of the Resolutions as each of the directors with personal holdings of equity
interests in the Company intends to do in respect of their own beneficial holdings.
Thank you for your ongoing support of Akari Therapeutics,Plc.
Yours sincerely,
/s/ Samir R. Patel
Samir R. Patel, M.D.
Interim President and Chief
Executive Officer
AKARI THERAPEUTICS, PLC
22 Boston Wharf Road, FL 7
Boston, Massachusetts 02210
NOTICE OF 2024 ANNUAL GENERAL MEETING OF SHAREHOLDERS
TO BE HELD ON THURSDAY, JUNE 27, 2024
NOTICE
is hereby given that the 2024 Annual General Meeting of Shareholders (referred to herein as the Meeting or
AGM) of Akari Therapeutics, Plc, a public limited company registered in England Wales (referred to herein
as Akari, the Company, our or we), will be held on Thursday, June27,
2024, at 2:00 p.m.London time (9:00 a.m.Eastern Time), at 75/76 Wimpole Street, London, W1G 9RT for transaction of the
following business:
Ordinary resolutions
1. To receive the report of the Board of Directors and the accounts
for the year ended December31, 2023, together with the report of the statutory auditor and the strategic report.
2. To approve the Board of Directors Remuneration Report (excluding
the Board of Directors Remuneration Policy), as set out in the Companys annual report and accounts for the financial year
ended December31, 2023.
3. To re-elect Donald Williams as a director of Akari, as a ClassA
Director as stated in Article18.2.1 of the Companys articles of association (the Articles).
4. To re-elect Michael Grissinger as a director of Akari, as a ClassA
Director as stated in Article18.2.1 of the Articles.
5.
To re-elect Mohamed WaEl Ahmed Hashad as a director of Akari, as a ClassA Director as stated in Article18.2.1
of the Articles.
6. To re-elect Samir Patel as a director of Akari, as a ClassA
Director as stated in Article18.2.1 of the Articles.
7. To re-elect Raymond Prudo-Chlebosz, M.D. as a director of Akari,
as a ClassC Director as stated in Article18.2.3 of the Articles.
8. To ratify the appointment of BDO USA, P.C. as independent registered
public accounting firm of Akari for the year ending December31, 2024.
9. To ratify the appointment of Haysmacintyre LLP as statutory auditors
of Akari to hold office until the conclusion of the next annual general meeting at which accounts are laid before Akari shareholders.
10. To authorize the audit committee of the Board of Directors of Akari
to fix the statutory auditors remuneration.
11. To approve, on a non-binding, advisory basis, the compensation
of our named executive officers (NEOs) as disclosed in this Proxy Statement.
12. To indicate, on a non-binding, advisory basis, the preferred frequency
of future shareholder advisory votes on the compensation of Akaris NEOs.
Pursuant to Regulation 41 of the Uncertificated Securities Regulations
2001, as amended, the Company specifies that entitlement to attend and vote at the Meeting, and the number of votes which may be cast
at the Meeting, will be determined by reference to the Companys register of members at 6:30 p.m.(London time) on June25,
2024 or, if the Meeting is adjourned, at 6:30 p.m.(London time) two working days before the time of the adjourned Meeting. In each
case, changes to the register of members after such time will be disregarded.
Any member may appoint a proxy to attend, speak and vote on his/her
behalf. A member may appoint more than one proxy in relation to the Meeting provided that each proxy is appointed to exercise the rights
attached to a different share or shares of the member. A proxy need not be a member, but must attend the Meeting in person. If a member
wishes his or her proxy to speak on his or her behalf at the AGM, he or she will need to appoint his or her own choice of proxy and give
his or her instructions directly to them. Completion and return of a proxy form will not preclude a member from attending, speaking and
voting at the AGM or any adjournment or postponement thereof in person. If a proxy is appointed and the member attends the AGM in person,
the proxy appointment will automatically be terminated. A validly appointed proxy shall be authorized (at his or her discretion) to consent
to any adjournment or postponement of the AGM and, unless otherwise terminated or amended in accordance with these notes or the notes
to the proxy form, the submitted proxy form shall remain effective at any such adjourned or postponed AGM. The proxy form, used by the
holders of ordinary shares to vote, should be lodged with the Companys registrar, Equiniti Group
,
not later than 2:00 p.m.(London
time) on June25, 2024. Completion and return of the appropriate proxy form does not prevent a member from attending and voting in
person if he/she is entitled to do so and so wishes. The accompanying Proxy Statement explains proxy voting and the matters to be voted
on in more detail. Please read the Proxy Statement carefully. For specific information regarding the voting of your ordinary shares, please
refer to the Proxy Statement under the section entitled
Questions and Answers About Voting
.
Any corporation which is a member can appoint one or more corporate
representatives who may exercise on its behalf all of its powers as a member provided that if it is appointing more than one corporate
representative, it does not do so in relation to the same shares. In the case of joint holders, the vote of the senior holder who tenders
the vote whether in person or by proxy will be accepted to the exclusion of the votes of any other joint holders. For these purposes,
seniority shall be determined by the order in which the names stand in the Companys relevant register or members for the certificated
or uncertificated shares of the Company (as the case may be) in respect of the joint holding.
Under section 527 of the U.K. Companies Act 2006, members meeting the
threshold requirement set out in that section have the right to require the Company to publish on a website a statement setting out any
matter relating to: (i)the audit of the Companys accounts (including the auditors report and the conduct of the audit)
that are to be laid before the Meeting; or (ii)any circumstance connected with an auditor of the Company ceasing to hold office
since the previous meeting at which annual accounts and reports were laid in accordance with section 437 of the U.K. Companies Act 2006.
The Company may not require the shareholders requesting any such website publication to pay its expenses in complying with sections 527
or 528 of the U.K. Companies Act 2006. Where the Company is required to place a statement on a website under section 527 of the U.K. Companies
Act 2006, it must forward the statement to the Companys auditor not later than the time when it makes the statement available on
the website. The business which may be dealt with at the Meeting includes any statement that the Company has been required, under section
527 of the U.K. Companies Act 2006, to publish on a website.
The accompanying Proxy Statement more fully describes the details of
the business to be conducted at the Meeting. After careful consideration, our Board of Directors has unanimously approved the Resolutions
and recommends that you vote FOR each resolution described in the accompanying Proxy Statement.
Resolutions 1 through 12 will be proposed as ordinary
resolutions and under English law, assuming that a quorum is present, an ordinary resolution is passed on a show of hands if it is approved
by a simple majority (more than 50%) of the votes cast by shareholders present (in person or by proxy) at the Meeting and entitled to
vote. If a poll is demanded, an ordinary resolution is passed if it is approved by holders representing a simple majority of the total
voting rights of shareholders present (in person or by proxy) who (being entitled to vote) vote on the resolution.
The Companys principal executive offices are located at 22 Boston
Wharf Road, FL 7, Boston, Massachusetts 02210. The registered office of Akari Therapeutics, Plc is Highdown House, Yeoman Way, Worthing,
West Sussex BN99 3HH. Except as set out in this Notice, any communication with the Company in relation to the Meeting, should be sent
to the Companys registrar, Equiniti Group. No other means of communication will be accepted. In particular, you may not use any
electronic address provided within this notice or in any related documents (including the Annual Report on Form10-K and statutory
annual accounts and reports for the year ended December31, 2023 and the proxy form) to communicate with the Company except as expressly
permitted.
You are reminded that you can update your preferences
for communications by Akari at any time through www.shareview.co.uk. You can contact Equiniti Group for assistance with the process on
+44 (0)371 384 2030. There is no charge for this service. Akari encourages you to agree to the use of electronic communications as it
will enable you to receive information quicker and reduce the Companys costs and environmental impact.
A
copy of the Statutory Accounts can be accessed by visiting the Akari website at
http://investor.akaritx.com/
.
Certificateless Registry for Electronic Share Transfer (CREST)
members who wish to appoint a proxy or proxies through the CREST electronic proxy appointment service may do so for the AGM and any adjournments
or postponements of it by using the procedures described in the CREST Manual (available via www.euroclear.com). CREST personal members
or other CREST sponsored members, and those CREST members who have appointed voting service providers, should refer to their sponsors
or voting service providers, who will be able to take the appropriate action on their behalf. For a proxy appointment or instruction made
using the CREST service to be valid, the appropriate CREST message (a CREST Proxy Instruction) must be properly authenticated
in accordance with Euroclears specifications and must contain the information required for those instructions as described in the
CREST Manual (available via www.euroclear.com). The message, regardless of whether it relates to the appointment of a proxy or to an amendment
to the instruction given to the previously appointed proxy, must, to be valid, be transmitted so as to be received by the Companys
agent (ID: RA19) by 9 am London time (4 am Eastern time) on June25, 2024. For this purpose, the time of receipt will be taken to
be the time (as determined by the timestamp applied to the message by the CREST Applications Host) from which the Companys agent
is able to retrieve the message by enquiry to CREST in the manner prescribed by CREST. After this time, any change of instructions to
proxies appointed through CREST should be communicated to the appointee through other means. CREST members and, where applicable, their
CREST sponsors or voting service providers should note that Euroclear UK does not make available special procedures in CREST for any particular
messages. Normal system timings and limitations will, therefore, apply in relation to the input of CREST Proxy Instructions. It is the
responsibility of the CREST member concerned to take (or, if the CREST member is a CREST personal member or sponsored member or has appointed
voting service providers, to procure that its CREST sponsors or voting service providers take) such action as shall be necessary to ensure
that a message is transmitted by means of the CREST system by any particular time. In this connection, CREST members and, where applicable,
their CREST sponsors or voting service providers are referred, in particular, to those sections of the CREST Manual concerning practical
limitations of the CREST system and timings. The Company may treat as invalid a CREST Proxy Instruction in the circumstances set out in
Regulation 35(5)(a)of the Uncertificated Securities Regulations 2001.
Your vote is important, regardless of the number of shares you own.
To make sure your shares are represented at the Meeting, please vote as soon as possible. The affirmative vote (on a show of hands or
a poll) of shareholders present in person or by proxy in accordance with the requisite majority set forth in the accompanying Proxy Statement
is required for approval of the Resolutions. We encourage you to read the Proxy Statement carefully.
Any member attending the Meeting has the right to ask questions. The
Company must cause to be answered any such question relating to the business being dealt with at the Meeting but no such answer need be
given if: (i)to do so would interfere unduly with the preparation for the Meeting or involve the disclosure of confidential information;
(ii)the answer has already been given on a website in the form of an answer to a question; or (iii)it is undesirable in the
interests of the Company or the good order of the Meeting that the question be answered.
The
Notice of the Meeting, the Proxy Statement, the Annual Report on Form10-K and the form of proxy are available in the Investors
Relations section of our website at
http://investor.akaritx.com/
and our U.K. statutory annual accounts and reports for
the financial year ended December31, 2023 shall be made available in the Investors Relations section of our website at
http://investor.akaritx.com/
no later than 21 days prior to the Meeting (collectively, the Proxy Materials). Information included on our website,
other than the Proxy Materials, is not part of our proxy soliciting materials.
Please complete, date, sign and return the
enclosed proxy form as promptly as possible (and in any event by 2:00 pm London time (9:00 am Eastern time) on June25, 2024)
in order to ensure your representation at the Meeting. Please note, however, that if your shares are represented by American
Depositary Shares and held on deposit by Deutsche Bank, or if your ordinary shares are held of record by a broker, bank or other
nominee, and you wish to have your votes cast at the Meeting, you must obtain, complete and timely return a proxy form issued in
your name from that intermediary in accordance with any instructions provided therewith.
By Order of the Board of Directors of Akari Therapeutics, Plc,
Highdown House, Yeoman Way, Worthing, West Sussex
BN99 3HH
PROXY STATEMENT FOR THE 2024 ANNUAL GENERAL
MEETING OF SHAREHOLDERS TO BE HELD ON JUNE 27, 2024
INFORMATION CONCERNING PROXY SOLICITATION AND
VOTING
We have sent you this Proxy Statement and the
enclosed proxy card because the Board of Directors (the Board of Directors or Board) of Akari Therapeutics,
Plc (referred to herein as the Company, we, us or our) is soliciting your proxy
to vote at our annual general meeting of shareholders (referred to herein as the Meeting or the AGM) to be
held at 2:00 p.m.London time (9:00 a.m.Eastern Time), on June27, 2024, at 75/76 Wimpole Street, London, W1G 9RT.
This Proxy Statement summarizes information about
the resolutions to be considered at the Meeting and other information you may find useful in determining how to vote. The form of proxy
is the means by which you actually authorize another person to vote your shares in accordance with your instructions.
In addition to solicitations by mail, our directors,
officers and regular employees, without additional remuneration, may solicit proxies by telephone, e-mail and personal interviews. All
costs of solicitation of proxies will be covered by us.
We are mailing the Notice of AGM, this Proxy Statement,
the proxy card and our Annual Report on Form10-K for the financial year ended December31, 2023 (the Annual Report on
Form10-K) to our ordinary shareholders of record as of May31, 2024 (being the latest practicable date before the circulation
of this document) for the first time on or about June3, 2024 and to our ADS holders on or about June5, 2024. In addition,
we have provided brokers, dealers, bankers, and their nominees, at our expense, with additional copies of our proxy materials so that
our record holders can supply these materials to the beneficial owners of our ordinary shares.
Our
U.K. statutory annual accounts and reports for the financial year ended December31, 2023 (the 2023 U.K. Annual Report)
shall only be made available in the Investors Relations section of our website at
http://investor.akaritx.com/
no later
than 21 days prior to the AGM. We will not be mailing copies of the 2023 U.K. Annual Report or the Annual Report on Form10-K to
our ordinary shareholders.
While this document is being sent to our ordinary
shareholders of record as of May31, 2024 (being the latest practicable date before the circulation of this document), this document
will also be sent to holders of American Depositary Shares (ADSs) and contains information relevant to holders of ADSs.
Important Notice Regarding
the Availability of Proxy Materials for the Shareholder Meeting to be Held on June27, 2024
Our
Notice of the AGM, this Proxy Statement, the Annual Report on Form10-K and our proxy card are available in the Investors Relations
section of our website at
http://investor.akaritx.com/
and the 2023 U.K. Annual Report will be available in the Investors
Relations section of our website at
http://investor.akaritx.com/
no less than 21 days prior to the AGM.
QUESTIONS AND ANSWERS ABOUT VOTING
Why am I receiving these materials?
We have sent you our Notice of AGM, this Proxy
Statement and the enclosed proxy card because you are either (i)an ordinary shareholder of record or (ii)an ADS holder of
record and our Board of Directors is soliciting your proxy to vote at the Meeting, including at any adjournments or postponements of the
Meeting. You do not need to attend the Meeting to vote your shares but you may if you wish. You may vote by proxy and your vote will be
cast on your behalf at the Meeting. To vote your shares whilst you are not in attendance, please simply complete, sign and return the
enclosed form of proxy in accordance with the instructions set out in this Proxy Statement. All proxies, however submitted, must be lodged
with our registrar, Equiniti Group, by no later than 2:00 pm London time (9:00 am Eastern time) on Tuesday, June25, 2024. CREST
members may appoint a proxy by using the CREST electronic proxy appointment service described above.
We intend to mail this Proxy Statement, the Annual
Report on Form10-K and the accompanying proxy card on or about June3, 2024 to all ordinary shareholders of record as of May31,
2024 (being the latest practicable date before the circulation of this document).
Materials for ADS holders of record, including
this Proxy Statement, the Annual Report on Form10-K and an ADS proxy card, will be mailed on or about June5, 2024 to all ADS
holders, including banks, brokers and nominees, who are registered as holders of ADSs in the ADS register
as of 5:00 p.m.Eastern
Time on May24, 2024 (the record date for ADS holders)
.
The
2023 U.K. Annual Report will be available in the Investors Relations section of our website at
http://investor.akaritx.com/
no less than 21 days prior to the AGM.
Who can vote at the Meeting?
Ordinary shareholders
Only ordinary shareholders of record registered
in the register of members at
6:30 p.m.London time (1:30 p.m.Eastern time) on Tuesday, June25, 2024
will be entitled
to vote at the Meeting. As of May24, 2024 (the record date for ADS holders) there were 15,847,391,523 ordinary shares, carrying
one vote each, issued and outstanding and entitled to vote. Each ADS of the Company represents two thousand (2,000) ordinary shares. As
an ordinary shareholder of record, you may vote at the AGM or by proxy. We encourage you to vote by proxy as instructed below to ensure
your vote is counted.
Beneficial owners of ordinary shares which are registered in
the name of a broker, bank or other agent
If, on May24, 2024, your ordinary shares
were held in an account at a brokerage firm, bank or other similar organization and you are the beneficial owner of shares, these proxy
materials should be forwarded to you by that organization. The organization holding your account is considered the shareholder of record
for purposes of voting at the Meeting. You are encouraged to provide voting instructions to your broker or other agent so that they may
submit a proxy.
Holders of American Depositary Shares
You are entitled to exercise your vote as a holder
of an interest in the capital of the Company represented by ADSs if you or your brokerage firm, bank or nominee is registered as a holder
of ADSs in the ADS register maintained by Deutsche Bank
as of 5:00 p.m.Eastern Time on Friday, May24, 2024 (the record
date for ADS holders).
If you hold ADSs through a brokerage firm, bank or nominee on May24, 2024, the materials for ADS holders,
including the ADS proxy card, will be sent to that organization. The organization holding your account is considered the ADS holder of
record. Please reach out to that organization to provide your voting instructions. Please note that ADS proxy cards submitted by ADS holders
must be received by Deutsche Bank
no later than 1:00 p.m.Eastern Time on June17, 2024
.
2
Deutsche Bank will collate all votes properly
submitted by ADS holders and submit a vote on behalf of all ADS holders.
What are the differences between ADS holders and ordinary shareholders?
Deutsche Bank, as depositary, executes and delivers
ADSs on our behalf. We are requesting the depositary, which holds the ordinary shares underlying the ADSs, to seek ADS holders
instructions as to voting for the AGM. As a result, ADS holders may instruct the depositary to vote the ordinary shares underlying their
ADSs.
Because we have asked the depositary to seek the
instructions of ADS holders, the depositary will notify ADS holders of the upcoming vote and arrange to deliver the proxy materials to
them. The depositary then tries, as far as practicable, to vote the ordinary shares as our ADS holders instruct. The depositary does not
vote or attempt to exercise the right to vote other than in accordance with the instructions of the ADS holders. We cannot guarantee that
ADS holders will receive this Proxy Statement and the other proxy materials from the depositary in time to permit them to instruct the
depositary to vote their shares. In addition, there may be other circumstances in which ADS holders may not be able to exercise voting
rights. Furthermore, ADS holders can exercise their right to vote the ordinary shares underlying their ADSs by exchanging their ADSs for
ordinary shares. However, even though we are subject to U.S. domestic issuer proxy rulesand our shareholder meetings are announced
via press release and filed with the U.S. Securities and Exchange Commission (SEC), ADS holders may not know about the Meeting
early enough to exchange their ADSs for ordinary shares.
ADS holders are not required to be treated as
holders of ordinary shares and do not have the rights of holders of ordinary shares.
What is the difference between a shareholder of record and a beneficial
owner?
These terms describe how your ordinary shares
are held. If your ordinary shares are registered directly in our register of members maintained by Equiniti Group, our registrar, you
are a shareholder of record and the proxy materials are being sent directly, or otherwise being made available, to you. If your ordinary
shares are held in the name of a broker, bank, or other nominee, you are a beneficial owner of the shares held by your broker, bank or
other nominee and the proxy materials are being made available or forwarded to you by your broker, bank, or other nominee, who is treated
as the shareholder of record. As the beneficial owner, you have the right to direct your broker, bank, or other nominee on how to vote
your ordinary shares by following the instructions on the voting instructions provided to you by such broker, bank or other nominee.
What are the requirements to elect the directors and approve each
of the resolutions?
You may cast your vote for or against resolutions 1 through 12 or abstain
from voting your shares on one or more of these resolutions.
Resolutions 1 through 12 will be proposed as ordinary
resolutions. Under English law, assuming that a quorum is present, an ordinary resolution is passed on a show of hands if it is approved
by a simple majority (more than 50%) of the votes cast by shareholders present (in person or by proxy) at the Meeting and entitled to
vote. If a poll is demanded, an ordinary resolution is passed if it is approved by holders representing a simple majority of the total
voting rights of shareholders present (in person or by proxy) who (being entitled to vote) vote on the resolution. It is intended that
voting on all resolutions at the Meeting will be conducted by way of poll. Broker non-votes will have no effect on the election of the
nominees.
The result of the shareholder votes on the ordinary
resolutions in resolutions 1, 2, 8, 9, 11 and 12 regarding receipt of our U.K. statutory annual accounts and reports for the financial
year ended December31, 2023, approval of our U.K. statutory directors annual report on remuneration for the financial year
ended December31, 2023, ratification of the appointment of Haysmacintyre LLP, a United Kingdom entity, as our U.K. statutory auditors,
ratification of the appointment of BDO USA, P.C., as our independent registered public accounting firm for the financial year ending December31,
2024, approval of our NEOs compensation, and preferred frequency of future shareholder advisory votes on the compensation of our
NEOs, will not require our Board of Directors or any committee thereof to take any action. Nonetheless, our Board of Directors values
the opinions of our shareholders as expressed through such votes and will carefully consider the outcome of the votes on resolutions 1,
2, 8, 9, 11 and 12.
3
What are the voting recommendations of our Board regarding the election
of directors and other resolutions?
The following table summarizes the items that
will be brought for a vote of our shareholders at the Meeting, along with the Boards voting recommendations.
Resolution
Description of Resolution
Boards
Recommendation
1
To receive the report of the Board of Directors and the accounts for the year ended December31, 2023, together with the report of the statutory auditor and the strategic report.
FOR
2
To approve the Board of Directors Remuneration Report (excluding the Board of Directors Remuneration Policy), as set out in the Companys annual report and accounts for the financial year ended December31, 2023.
FOR
3
Re-appointment of Donald Williams as a director of Akari, as a ClassA Director as stated in Article18.2.1 of the Companys Articles.
FOR
4
Re-appointment of Michael Grissinger as a director of Akari, as a ClassA Director as stated in Article18.2.1 of the Articles.
FOR
5
Re-appointment of Mohamed WaEl Ahmed Hashad as a director of Akari, as a ClassA Director as stated in Article18.2.1 of the Articles.
FOR
6
Re-appointment of Samir Patel as a director of Akari, as a ClassA Director as stated in Article18.2.1 of the Articles.
FOR
7
Re-appointment of Raymond Prudo-Chlebosz, M.D. as a director of Akari, as a ClassC Director as stated in Article18.2.3 of the Articles.
FOR
8
To ratify the appointment of BDO USA, P.C. as independent registered public accounting firm of Akari for the year ending December31, 2024.
FOR
9
Ratify the appointment of Haysmacintyre LLP as statutory auditors of Akari to hold office until the conclusion of the next annual general meeting at which accounts are laid before Akari shareholders.
FOR
10
To authorize the audit committee of the Board of Directors of Akari to fix the statutory auditors remuneration.
FOR
11
To approve, on a non-binding, advisory basis, the compensation of our NEOs as disclosed in this Proxy Statement.
FOR
12
To indicate, on a non-binding, advisory basis, the preferred frequency of future shareholder advisory votes on the compensation of Akaris NEOs.
FOR 1 YEAR
What constitutes a quorum?
Consistent
with the Nasdaq Stock Market LLC (Nasdaq) rulesapplicable to us as a U.S. domestic registrant and in accordance with
our Articles of Association, we require qualified persons present at a meeting and between them holding (or being the proxy or corporate
representative of the holders of) at least 33
1
/3
% of the Companys share
capital (excluding any shares held as treasury shares) entitled to vote on the business to be transacted at the Meeting.
If you are an ordinary shareholder of record,
your shares will be counted towards the quorum only if you are present in person or represented by proxy at the Meeting. If you are a
beneficial owner of ordinary shares held in an account at a brokerage firm, bank or other similar organization your shares will be counted
towards the quorum if your broker or nominee submits a proxy for those shares and the proxy represents the holder at the Meeting. A member
represented by a proxy at the Meeting will be counted towards the quorum requirement even where the proxy abstains from voting. If a form
of proxy does not instruct the proxy how to vote, the proxy may vote as he or she sees fit or abstain in relation to any business of the
Meeting, but the member represented by that proxy at the Meeting will be counted towards the quorum requirement.
4
If
a quorum is not present (and unless the Meeting was convened on requisition of, or by, members), it will stand adjourned to the same
day in the next week at the same time and place (or places), or to such other day and at such other time and place (or places) as the
Board of Directors may determine. We require a quorum of at least 33
1
/3
percent of the Companys
share capital (excluding any shares held as treasury shares) entitled to attend and vote on the business to be transacted if the Meeting
is reconvened, consistent with the Nasdaq rulesapplicable to us as a U.S. domestic registrant and our Articles of Association.
If such quorum is not present at the adjourned meeting within 15 minutes, the member or members present in person or by proxy and entitled
to vote will have power to decide upon all matters which could properly have been disposed of at the meeting as originally convened.
How do I vote my shares?
You may vote For, Against,
For 1 year, For 2 years, or For 3 years (in the case of Resolution 12), or abstain from voting
on the applicable resolutions.
If
you are an ordinary shareholder of record
, you may appoint a proxy to vote on your behalf by completing and signing
the form of proxy and returning it in the envelope provided. We urge you to vote by proxy as instructed below to ensure your vote is counted.
You may still attend the AGM and vote in person during the AGM even if you have already voted by proxy.
All proxies must be lodged with our registrar
(Equiniti Group) by no later than
2:00 p.m.London time (9:00 a.m.Eastern Time) on Tuesday, June25, 2024.
You may appoint more than one proxy in relation
to the AGM (provided that each proxy is appointed to exercise the rights attached to a different ordinary share(s)). To appoint more than
one proxy, you should contact our registrar, Equiniti Group. Such proxy need not be a shareholder of record but must attend the AGM to
represent you for your vote to be counted. You are encouraged to appoint the Chairman of the Meeting as your proxy. If you appoint any
person other than the Chairman of the Meeting as your proxy, that person may not be entitled to attend the Meeting.
If you properly give instructions as to your proxy
appointment by executing and returning a form of proxy and your proxy appointment is not subsequently revoked, your shares will be voted
in accordance with your instructions.
If
your ordinary shares are held in an account at a brokerage firm, bank or similar organization
, you should follow directions
provided by your broker, bank or other nominee.
If
you are a holder of ADSs
, you should follow the directions on the ADS proxy card you received. Please note that ADS proxy cards
submitted by ADS holders must be received by Deutsche Bank no later than
no later than 1:00 p.m.Eastern Time on June17,
2024.
Deutsche Bank will collate all votes properly submitted by ADS holders and submit a vote on behalf of all ADS holders. Holders
of ADSs are not entitled to attend and vote at the AGM in person.
How will my shares or ADSs be voted if I do not specify how they
should be voted?
If you sign and send your form of proxy but do
not indicate how you want your shares to be voted, your shares may be voted by the person that you appoint as your proxy as he or she
sees fit or such person may abstain in relation to any business of the Meeting. As a reminder, we urge all shareholders to appoint the
Chairman of the AGM as your proxy.
If you are a beneficial owner of ordinary shares
and your broker, bank or nominee does not receive instructions from you about how your shares are to be voted, such broker, bank or nominee
may either vote these shares on behalf of the beneficial owners if permitted by applicable rulesor return a proxy leaving these
shares un-voted (a broker non-vote). A broker non-vote refers to a share represented at the meeting held by
an organization, as to which instructions have not been received from the beneficial owner or person entitled to vote such shares and
with respect to which, on one or more, but not all matters, the broker does not have discretionary voting power to vote such share. Generally,
brokers have discretionary voting power to vote shares with respect to resolutions that are considered routine, while they
do not have such power with respect to resolutions that are non-routine. Resolutions 2-7, 11, and 12 are considered non-routine
matters under applicable rules, while resolutions 1 and 8-10 are considered routine matters. We encourage you to submit your proxy with
instructions and exercise your right to vote as a shareholder.
5
With respect to any properly completed voting
instructions received by Deutsche Bank on or prior to 6:00 p.m.London time (1:00 p.m.Eastern time) on June17, 2024,
Deutsche Bank shall endeavor, insofar as practicable and permitted under applicable law, the provisions of the deposit agreement by and
among the Company, Deutsche Bank, as depositary, and holders and beneficial owners of ADSs issued thereunder dated as of December7,
2012 (as amended), and the Articles, to vote or cause its custodian to vote the shares (in person or by proxy) represented by ADSs in
accordance with such voting instructions, for holders of ADSs as of 5:00 p.m.Eastern Time on May24, 2024 (the record date
for ADS holders). Shares represented by ADSs for which no specific voting instructions are received by Deutsche Bank from the ADS holder
shall not be voted.
Can I change my vote or revoke a proxy?
A registered ordinary shareholder can revoke his
or her proxy before the time of voting at the Meeting by:
a)
Mailing a revised form of proxy dated later than the prior form of proxy; or
b)
Notifying our Company Secretary in writing that you are revoking your proxy. Your revocation must be received
at our registered office before the Meeting to be effective.
A shareholder would also be able to revoke his
or her proxy by voting in person at the Meeting. If your ordinary shares are held in an account at a brokerage firm, bank or similar organization,
you may change or revoke your voting instructions by contacting the broker, bank or other nominee holding the shares or by your broker,
bank or other nominee validly appointing you as proxy to attend at the Meeting. See also What if I plan to attend the Meeting?
If you hold ADSs, directly or through a broker,
bank or other nominee, you must follow the instructions provided by Deutsche Bank or such broker, bank or other nominee if you wish to
change your vote. The last instructions you submit prior to the deadline indicated by Deutsche Bank or the broker, bank or other nominee,
as applicable, will be used to instruct Deutsche Bank how to vote your ADSs.
Who counts the votes?
Equiniti Group has been engaged as our independent
agent to tabulate shareholder votes. If you are an ordinary shareholder of record, you can return your executed form of proxy to Equiniti
Group for tabulation (see instructions on the form of proxy).
If you hold your ordinary shares through a broker,
your broker will return the form of proxy to Equiniti Group.
If you are a holder of record of ADSs, you can
return your executed ADS proxy card to Deutsche Bank for tabulation. If you hold your ADSs through a broker, bank or other organization,
that organization can return the ADS proxy card to Deutsche Bank following your instruction. Deutsche Bank will submit your votes to Equiniti
Group for tabulation.
What is an abstention and how would it affect the
vote?
An abstention is not a vote in law and will not
be counted in the calculation of the proportion of the votes for or against a particular resolution.
6
How many votes do I have?
On a show of hands, each ordinary shareholder
of record present in person, and each duly authorized representative present in person of a shareholder that is a corporation, has one
vote. On a show of hands, each proxy present in person who has been duly appointed by one or more shareholders has one vote, but a proxy
has one vote for and one vote against a resolution if, in certain circumstances, the proxy is instructed by more than one shareholder
to vote in different ways on a resolution. On a poll, each shareholder present in person or by proxy or, in the case of a corporation,
by a duly authorized representative has one vote for each share held by the ordinary shareholders of record as of
Friday, May24,
2024
.
On each matter to be voted upon, each holder of
ADSs has one vote for each ADS held as of May24, 2024. Each ADS of the Company represents two thousand (2,000) ordinary shares.
What about joint holders?
In the case of joint holders of record of an ordinary
share, the vote of the senior who tenders the vote (whether in person or by proxy) will be accepted to the exclusion of the votes of any
other joint holders. For these purposes, seniority shall be determined by the order in which the names stand in our relevant register
of members of the company (as the case may be) in respect of the joint holding (with the first named being the most senior).
What if I plan to attend the Meeting?
Ordinary shareholders can attend the Meeting,
but attendance will be limited to ordinary shareholders of record. In order to obtain admittance to the Meeting each shareholder may be
asked to present valid picture identification, such as a drivers license or passport. If your ordinary shares are held through
brokerage accounts or by a bank or other nominee you may be able to attend at the discretion of the Chairman. Any corporation which is
an ordinary shareholder of record may by resolution of its directors authorize one or more persons to act as its representative(s)at
the AGM and the person(s)so authorized shall (on production of a certified copy of such resolution at the AGM) be entitled to exercise
these same powers on behalf of the corporation as the corporation could exercise if it were one of our individual shareholders.
How do you solicit proxies?
We will solicit proxies and will bear the entire
cost of this solicitation. The initial solicitation of proxies may be supplemented by additional mail communications and by telephone,
fax, e-mail, internet and personal solicitation by our directors, officers or other employees. No additional compensation for soliciting
proxies will be paid to our directors, officers or other employees for their proxy solicitation efforts. We also reimburse Deutsche Bank
for their expenses in sending materials, including ADS proxy cards, to ADS holders of record.
What do I do if I receive more than one notice or form of proxy?
If you hold your ordinary shares in more than
one account, you will receive a form of proxy for each account. To ensure that all of your shares are voted, please sign, date and return
all forms of proxy. Please be sure to vote all of your shares.
If you hold ADSs in your own name registered on
the books of the depositary, you are considered the registered holder of the ADSs and will receive the proxy materials from the Depositary.
If you hold ADSs through a broker, bank or other nominee, you are considered the beneficial owner of the ADSs and you will receive the
proxy materials from your broker, bank or other nominee.
7
Will there be any other business conducted at the Meeting?
Subject to any shareholder resolutions submitted
in accordance with section 338 of the U.K. Companies Act 2006 (as summarized below). In accordance with our Articles of Association, no
matters other than resolutions 1 through 12 may be presented at this Meeting. We have not been notified of, and our Board is not aware
of, any other matters to be presented for action at the Meeting.
Under section 338 of the Companies Act, shareholders
meeting the threshold requirement in that section may require us to give to our shareholders entitled to receive this notice of the AGM
notice of a resolution which may properly be moved and is intended to be moved at the AGM unless (i)it would, if passed, be ineffective
whether by reason of inconsistency with any enactment or our constitution or otherwise, (ii)it is defamatory of any person or (iii)it
is frivolous or vexatious. Such a request may be in hard copy form or in electronic form, must identify the resolution of which notice
is to be given, must be authorized by the person or persons making it and must have been received by us not later than May16, 2024,
the date six weeks before the AGM.
What is Equiniti Groups role?
Equiniti Group is our registrar. All communications
concerning ordinary shareholder of record accounts, including address changes, name changes, ordinary share transfer requirements and
similar issues can be handled by contacting Equiniti Group by writing to Equiniti Group at, Aspect House, Spencer Road, Lancing, West
Sussex BN99 6DA.
Communications concerning ADS holder of record
accounts can be handled by contacting Deutsche Bank c/o Equiniti Trust Company, by telephone at: +1 (800) 937-5449 (toll free within the
United States) or +1 (718) 921-8137 (for international callers) or by email: adr@equiniti.com or by mail at Deutsche Bank, Deutsche Bank
Trust Company Americas, c/o Equiniti Trust Company, Peck Slip Station PO Box 2050 New York, NY 10272-2050.
How can I find out the results of the voting at the Meeting?
Voting results will be announced by the filing
of a current report on Form8-K with the SEC within four business days following the Meeting. If final voting results are unavailable
at that time, we will file an amended current report on Form8-K within four business days of the day the final results are available.
Who do I contact regarding my ADS holdings?
If you are an ADS holder of record and have queries
about how to deliver voting instructions, please contact Deutsche Bank c/o Equiniti Trust Company, by telephone at +1 (800) 937-5449 (toll
free within the United States) or +1 (718) 921-8137 (for international callers) or by email at adr@equiniti.com or at by mail at Deutsche
Bank, Deutsche Bank Trust Company Americas, c/o Equiniti Trust Company, Peck Slip Station PO Box 2050 New York, NY 10272-2050. If you
hold your ADSs through a custodian, broker or other agent, you should refer to the contact information provided by your agent.
What do I do if I have additional questions?
If you have any further questions about voting
or attending the AGM, please contact Joe Carroll, Company Secretary, by email at joe.carroll@akaritx.com or by telephone at +1 (929) 274-7511.
RESOLUTION 1 STATUTORY ACCOUNTS
As
a public limited company, it is a requirement under English company law that the Board of Directors lay the report of the Companys
directors and the Companys accounts for the year ended December31, 2023, together with the report of the statutory auditor
and the strategic report (the Statutory Accounts) before the shareholders at a general meeting. The Statutory Accounts
have been prepared in accordance with the Companies Act and International Financial Reporting Standards. The Statutory Accounts are available
for download on the Companys website (
http://investor.akaritx.com/
).
In addition, hard copies of the Statutory
Accounts may be obtained by contacting the Registrars
.
8
THE BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
THE RESOLUTION TO RECEIVE AND ADOPT THE COMPANYS STATUTORY ACCOUNTS
RESOLUTION 2 - APPROVAL OF DIRECTORS
REMUNERATION REPORT SET FORTH IN ANNEX A
Our U.K. statutory directors remuneration
report is set forth as Annex A to this Proxy Statement. The directors remuneration report includes the annual report on remuneration.
This document describes in detail our remuneration policies and procedures and explains how these policies and procedures help to achieve
our compensation objectives with regard to our directors and the retention of high-quality directors. Our Board of Directors and the compensation
committee believe that the policies and procedures as articulated in the directors remuneration report are effective and that as
a result of these policies and procedures we have and will continue to have high-quality directors. Our Board of Directors has approved
and signed the report in accordance with English law.
At the Meeting, the shareholders will vote on
the annual report on remuneration. This vote is advisory and non-binding. Although non-binding, our Board of Directors and compensation
committee will review and consider the voting results when making future decisions regarding our director remuneration program. Following
the Meeting, and as required under English law, the directors annual report on remuneration will be delivered to the U.K. Registrar
of Companies.
The affirmative vote of holders representing a
simple majority of the total voting rights of shareholders present in person or by proxy who (being entitled to vote) vote on the matter
will be required to pass this resolution. This vote is advisory and non-binding and the directors entitlement to receive remuneration
is not conditional on it. Payments made or promised to directors will not have to be repaid, reduced or withheld in the event that the
resolution is not passed. Although non-binding, our Board of Directors and compensation committee will review and consider the voting
results when making future decisions regarding our director remuneration program. Following the AGM, and as required under English law,
the directors annual report on remuneration will be delivered to the U.K. Registrar of Companies.
THE BOARD OF DIRECTORS RECOMMEND YOU VOTE
FOR
APPROVAL OF OUR U.K. STATUTORY DIRECTORS ANNUAL REPORT ON REMUNERATION
SET FORTH IN ANNEX A
RESOLUTIONS 3 TO 7 - RE-APPOINTMENT OF DIRECTORS
Under the Companys Articles of Association,
there are three classes of Board members (ClassA, ClassB and ClassC) with each class having a specific office term.
Samir R. Patel, Wael Hashad, Donald Williams, and Michael Grissinger currently serve as ClassA directors and Raymond Prudo-Chlebosz,
M.D. currently serves as a ClassC director. We currently do not have any ClassB directors. Subject to the matters described
below, Samir R. Patel, Wael Hashad, Donald Williams and Michael Grissinger have been nominated by the Board of Directors to be
re-elected as ClassA directors at the Meeting. A ClassA director re-elected at the Meeting will hold office until the 2025
annual general meeting unless they resign or their seats become vacant due to death, removal, or other cause in accordance with the Articles.
If re-elected at the Meeting, Raymond Prudo-Chlebosz, M.D. will remain in office as a ClassC director, until the 2027 Annual General
Metting unless he resigns or his seat become vacant due to death, removal, or other cause in accordance with the Articles.
In connection with resolutions 3, 4, 5, 6, and
7, we set forth the biographical information for the nominees to our Board of Directors.
Donald
Williams
,
has served as a member of our board of directors since June2016 and is an audit committee
financial expert. Mr.Williams is a 35-year veteran of the public accounting industry who retired in 2014. Mr.Williams
spent 18 years of his career as a partner at Ernst Young, followed by seven years as a partner at Grant Thornton. During his
time at Grant Thornton from 2007 to 2014, he served as the national leader of Grant Thorntons life sciences practice and the managing
partner of the San Diego Office. He was the lead partner for both Ernst Young and Grant Thornton on multiple initial public
offerings, secondary offerings, and private and public debt financings, as well as numerous mergers and acquisitions. Mr.Williams
currently serves as a director of Forte Biosciences,Inc. (NASDAQ: FBRX), Palisade Bio,Inc. (NASDAQ: PALI), and MONIA, a privately
held company. Previously, Mr.Williams served as a director of Impedimed Limited (ASX: IPD) from 2017 to September2023, Alphatec
Spine (NASDAQ: ATEC) from 2015 to August2021, and Adhera Therapeutics (OTC: ATRX) from 2014 to December2019. Mr.Williams
is a graduate of Southern Illinois University with a B.S. degree.
9
Michael
Grissinger
, has served as a member of our board of directors since January2018. Mr.Grissinger spent 22 years
at Johnson Johnson, retiring in 2018. During his Johnson and Johnson tenure, Mr.Grissinger served in a variety of senior-level
management roles including Vice President and Head, Worldwide Pharmaceutical Licensing as well as Vice President and Head of Worldwide
Pharmaceutical Corporate Development and MA. Prior to Johnson Johnson, Mr.Grissinger spent 12 years at Ciba-Geigy
in finance, marketing, and business development roles. In addition to Akari, Mr.Grissinger also serves as a member of the board
of directors of Aprea Therapeutics,Inc. (NASDAQ: APRE), and three privately-held biotechnology companies, Atriva Therapeutics Plc,
Kira Biotech Pty Ltd., and Envisagenics,Inc. Mr.Grissinger holds a B.Sc. in Chemistry from Juniata College and an MBA from
Temple University, Fox School of Business.
Raymond
Prudo-Chlebosz, M.D.
, served as our Executive Chairman from September2015 through December2022. Effective January1,
2023. Dr.Prudo began serving as the Chairman of our board of directors. Dr.Prudo has been an active investor and developer
of healthcare companies for 25 years. Dr.Prudo was the Founder, Chairman, and Chief Executive Officer of Volution and its predecessor
company, Varleigh Immuno Pharmaceuticals, since its inception in 2008. Dr.Prudo is also the co-founder of The Doctors Laboratory
(TDL), past CEO and its Chairman since 2002. Since 2015 he has also been a director of Health Services Laboratories (HSL).
Both TDL and HSL are subsidiaries of Sonic Healthcare Limited (ASX: SHL.AX). Dr.Prudo is also currently a director of CIS Healthcare
Limited, a privately-held UK healthcare company. Dr.Prudo holds an MBBS from the University of London, and an FRCP(C)from
the Royal College of Physicians and Surgeons of Canada.
Wael
Hashad
, has served as a member of our board of directors since July2023. Mr.Hashad currently serves as CEO
of Longeveron, a U.S. clinical-stage biotechnology company developing regenerative medicines for rare pediatric diseases, aging-related
conditions, and unmet medical needs. Previously, he was President and Chief Executive Officer at Avanir Pharmaceuticals, a position he
held from July2017 to December2022. From January2016 to June2017, Mr.Hashad served as Executive Vice President
and Chief Commercial Officer at Seres Therapeutics. Mr.Hashad has also held multiple leadership roles at Amgen and Boehringer Ingelheim.
Earlier in his career, Mr.Hashad spent 20 years at Eli Lilly and Company, driving the companys marketing and commercial strategy
across multiple regions and therapeutic areas. Mr.Hashad holds an M.B.A. in Finance and International Business from the University
of Akron and a B.Sc. in Pharmacy and Pharmaceutical Sciences from the University of Cairo. He is currently a board member of California
Life Sciences.
Samir
R. Patel, M.D
., has served as a member of our board of directors since December2023. In May2024, Dr.Patel
was appointed as the Interim Chief Executive Officer of the Company. Dr.Patel is the founder and principal of PranaBio Investments,
LLC, a firm providing consulting, strategic advisory, and investment services for small cap biotechnology companies, which he founded
in April2017. Since May2019, he has also served as a consultant to GE Global Research, GEs innovation engine
that is creating novel products and solutions across several sectors including biomanufacturing and biotechnology. Dr.Patel has
more than 20 years of experience in life sciences including co-founding Digital Therapeutics, LLC, a startup advancing a therapy for scleroderma
and other rheumatic diseases, in August2011, and SPEC Pharma, LLC, a company he founded in September2003, which develops and
manufactures injectables used in rheumatology applications. Previously, he held multiple roles in Medical Affairs with Centocor,Inc.
(now Johnson Johnson Innovative Medicine, part of Johnson Johnson). Dr.Patel served on the board of directors
of CytoDyn Inc. from April2020 to November2021. Dr.Patel received his medical degree from the Medical College of Ohio
(University of Toledo) in Toledo, Ohio, and completed his internal medicine internship and residency, as well as a rheumatology fellowship,
at University of New Mexico School of Medicine Affiliated Hospitals.
The affirmative vote of the holders of a majority
of the shares entitled to vote and who are present at the Meeting or represented by proxy at the Meeting will be required to re-appoint
Samir R. Patel, Wael Hashad, Donald Williams, and Michael Grissinger as ClassA Directors and Raymond Prudo-Chlebosz, M.D.
as a ClassC Director of Akari.
10
THE
BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
THE RE-APPOINTMENT OF SAMIR R. PATEL, WAEL HASHAD, DONALD WILLIAMS, AND
MICHAEL GRISSINGER AS CLASSA
DIRECTORS AND RAYMOND PRUDO-CHLEBOSZ, M.D. AS A CLASSC DIRECTOR OF AKARI, EACH OF WHOM WILL RETIRE BY ROTATION IN ACCORDANCE WITH
THE ARTICLES
RESOLUTION 8 - RATIFICATION OF APPOINTMENT OF
INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
Background to Resolution 8
Our audit committee has appointed BDO USA, P.C.
to serve as our independent registered public accounting firm for the year ending December31, 2024. The audit committee and the
Board of Directors are requesting, as a matter of policy, that shareholders ratify the selection of BDO USA, P.C. The audit committee
and the Board of Directors are not required to take any action as a result of the outcome of the vote on this resolution. Even if the
appointment is ratified, the Board of Directors may, in its discretion, appoint a different independent registered public accounting firm
at any time during the year if they determine that such a change would be in the best interests of the Company and its shareholders. If
the appointment is not ratified, the Board of Directors will consider its options.
BDO USA, P.C. has indicated its willingness to
act as the Companys auditor. A representative of BDO USA, P.C. is not expected to be present at the Meeting.
Fees for BDO USA, P.C.
The table below sets forth a summary of the fees
billed to the Company by BDO USA, P.C. for professional services rendered during the financial years ended December31, 2023 and
December31, 2022, respectively. All such services and fees were pre-approved by the audit committee, which concluded that the provision
of such services was compatible with the maintenance of each firms independence in the conduct of its auditing functions.
Fee Category
2023
2022
Audit Fees
$
344,384
$
280,455
Audit-Related Fees
-
-
Tax Fees
40,000
-
All Other Fees
-
-
Total Fees
$
384,384
$
280,455
Audit Fees
Audit fees represent the aggregate fees for professional services rendered
by our independent registered public accounting firm for: (i)the audit of our annual consolidated financial statements, (ii)review
of our interim financial statements filed on Form6-K that are customary under the standards of the Public Company Accounting Oversight
Board (United States), and (iii)issuance of consents in connection with the filing of registration statements and related post-effective
amendments.
Tax Fees
Tax fees consist of all services, except those services specifically
related to the audit of the financial statements, performed by the independent registered public accounting firms tax personnel,
including tax compliance and reporting. Tax fees during 2023 primarily related to the conduct of a IRS Section382 study. No such
fees were incurred during 2022.
Audit Committee Pre-Approval Policy and Procedures
Our audit committee has adopted policies and procedures relating to
the approval of all audit and non-audit services that are to be performed by our independent registered public accounting firm. This policy
generally provides that we will not engage our independent registered public accounting firm to render audit or non-audit services unless
the service is specifically approved in advance by the audit committee, or the engagement is entered into pursuant to the pre-approval
procedures described below.
11
From time to time, the audit committee may pre-approve
specified types of services that are expected to be provided to us by our independent registered public accounting firm during the next
12 months. Any such pre-approval is detailed as to the particular service or type of services to be provided and is also generally subject
to a maximum dollar amount. All of the services described above under the headings Audit Fees and Tax Fees
were pre-approved by our audit committee.
THE BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
THE RATIFICATION OF THE RE-APPOINTMENT BDO USA, P.C., AS OUR
INDEPENDENT REGISTERED PUBLIC ACCOUNTING
FIRM FOR THE FINANCIAL YEAR ENDING DECEMBER 31, 2024
RESOLUTION 9 - RATIFY THE APPOINTMENT OF STATUTORY
AUDITOR
At every general meeting at which accounts are
presented to shareholders, Akari is required to appoint statutory auditors to serve from the end of the meeting until the conclusion of
the next general meeting at which accounts are laid before Akari shareholders. Haysmacintyre LLP has indicated that it is willing to continue
as Akaris statutory auditor to hold office during this period. You are asked to approve their re-appointment.
THE BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
RATIFYING THE APPOINTMENT OF HAYSMACINTYRE LLP AS AKARIS STATUTORY AUDITORS, TO SERVE UNTIL THE CONCLUSION OF THE NEXT GENERAL
MEETING AT WHICH THE COMPANYS ANNUAL ACCOUNTS ARE LAID BEFORE THE COMPANYS SHAREHOLDERS
RESOLUTION 10 - AUTHORIZATION FOR THE AUDIT
COMMITTEE TO DETERMINE THE STATUTORY AUDITORS REMUNERATION FOR THE FINANCIAL YEAR ENDING DECEMBER 31, 2024
Resolution 10 authorizes the audit committee to
determine our statutory auditors remuneration for the financial year ending December31, 2024.
THE BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
THE AUTHORIZATION OF OUR AUDIT COMMITTEE TO DETERMINE OUR STATUTORY AUDITORS REMUNERATION FOR THE FINANCIAL YEAR ENDING DECEMBER
31, 2024
RESOLUTION
11
TO APPROVE, ON A NON-BINDING, ADVISORY BASIS, THE COMPENSATION OF AKARIS NEOs AS DISCLOSED IN THIS PROXY
STATEMENT.
We are providing our shareholders the
opportunity to vote to approve, on an advisory, non-binding basis, the compensation of our NEOs as disclosed in this Proxy Statement
in accordance with the SECs rules. This resolution, which is commonly referred to as say-on-pay, is required by
the Dodd-Frank Act, which added Section14A to the Securities Exchange Act of 1934, as amended (the Exchange
Act). Our executive compensation program is designed to reward value creation for shareholders and to attract, motivate, and
retain our executive officers, who are critical to our success. Under this program, our NEOs are rewarded for the achievement of our
short- and long-term strategic and financial goals, which we believe serves to enhance short- and long-term value creation for our
shareholders. Our compensation program contains elements of cash and equity-based compensation and is designed to align the
interests of our executives with those of our shareholders.
The section of this Proxy Statement entitled
Named
Executive Officer Compensation
, describes in detail our executive compensation program and the decisions made by our compensation
committee.
As an advisory vote, the outcome of the vote on
this resolution is not binding and does not overruleany decision by the company or the Board of Directors (or any committee thereof),
create or imply any change to the fiduciary duties of the company or the Board of Directors (or any committee thereof), or create or imply
any additional fiduciary duties for the company or the Board of Directors (or any committee thereof). However, our compensation committee
and Board of Directors value the opinions expressed by our shareholders in their vote on this resolution and intend to consider carefully
the outcome of the vote when making future compensation decisions for any NEOs.
12
THE BOARD OF DIRECTORS RECOMMEND A VOTE
FOR
THE APPROVAL, ON A NON-BINDING, ADVISORY BASIS, OF THE COMPENSATION OF OUR NEOs AS DISCLOSED IN THIS PROXY STATEMENT.
RESOLUTION 12 - TO INDICATE, ON A NON-BINDING,
ADVISORY BASIS, THE PREFERRED FREQUENCY OF FUTURE SHAREHOLDER ADVISORY VOTES ON THE COMPENSATION OF AKARIS NEOs.
Section14A(a)(2)of the Exchange
Act enables our shareholders to vote, on anon-binding,advisory basis,
on how frequently we should submit futuresay-on-payvotes, similar to Resolution 11, on the compensation of
our NEOs. Under Section14A(a)(2)of the Exchange Act, generally, each public company must submit this resolution to its
shareholders not less than every six years, and this would be the first instance in which such a vote is submitted to the
Companys shareholders, and as we are no longer a Foreign Private Issuer, we are now subject Section1A(a)(2).
Shareholders may choose to recommend that futuresay-on-payresolutions
be held (i)every year (FOR 1 YEAR on the proxy card), (ii)every two years (FOR 2 YEARS on the
proxy card) or (iii)every three years (FOR 3 YEARS on the proxy card). In addition, shareholders may choose to abstain
from voting on this Resolution 12.
After careful consideration, our Board of Directors
recommends that futurenon-binding,advisory votes on executive compensation should be held every year. Annual votes will provide
the Board of Directors and the compensation committee with the most timely feedback regarding the compensation of our NEOs. The primary
focus of the disclosure of the compensation of our NEOs required to be included in our Proxy Statements is compensation granted in or
for the prior fiscal year. Accordingly, an annual executive compensation advisory vote will complement the annual focus of our Proxy Statement
disclosure and provide the Board of Directors and compensation committee with the clearest and most timely feedback of the three frequency
options. Additionally, an annual executive compensation advisory vote is consistent with our policy of reviewing our compensation programs
annually, as well as considering input from our shareholders on corporate governance and executive compensation matters. This feedback
may then be considered by the Board of Directors and compensation committee in their annual decision-making process. For these reasons,
we believe an annual vote would be the best governance practice for the Company at this time. This vote is advisory, and therefore not
binding on the Board of Directors or compensation committee. However, the Board of Directors and compensation committee value the opinions
of our shareholders and intend to take into account the outcome of the vote when considering the frequency of holding future advisory
votes on the compensation of our NEOs.
THE BOARD OF DIRECTORS RECOMMEND THAT SHAREHOLDERS
VOTE, ON A NON-BINDING, ADVISORY BASIS, FOR EVERY YEAR (FOR 1 YEAR ON THE PROXY CARD) AS THE FREQUENCY FOR FUTURE NON-BINDING,
ADVISORY, SHAREHOLDER VOTES REGARDING THE COMPENSATION OF OUR NEOs.
BOARD OF DIRECTORS AND CORPORATE GOVERNANCE
BOARD OF DIRECTORS
Structure of Our Board of Directors
Our Articles of Association provide that our business
is to be managed by the Board of Directors (subject to any directions made by the members of the Company by special resolution). Our Board
of Directors is divided into three classes for purposes of election (ClassA Directors, who serve a one year term before being subject
to re-election at the Companys annual general meeting; ClassB Directors, who serve a two year term before being subject to
re-election at the annual general meeting; and ClassC Directors who serve a three year term before being subject to re-election
at the annual general meeting, provided also that in any two year period, a majority of the Board of Directors must stand for re-election).
Information about our Directors
Set forth below is information about each member of our board of directors,
including (a)the year in which each director first became a director, (b)their age as of May24, 2024, and (c)their
positions and offices with our Company. We believe that all of our directors have a reputation for integrity, honesty and adherence to
high ethical standards. They each have demonstrated business acumen and an ability to exercise sound judgment, as well as a commitment
of service to our Company and our board of directors.
The following table provides information about those persons who currently
serve as directors of the Company.
Committee Memberships (1)
Name
Age
Relationship
Audit
Comp
NCG
Class- Election Year
Raymond Prudo-Chlebosz, M.D.
79
Chair of the Board of Directors
ClassC Director - 2024
Michael Grissinger
68
Director
X
X
C
ClassA Director - 2024
Wael Hashad
61
Director
X
X
ClassA Director - 2024
Samir R. Patel, M.D.
55
Director
ClassA Director - 2024
Donald Williams
65
Director
C
C
X
ClassA Director - 2024
(1)C indicates Chair of applicable
committee.
During the year ended December31, 2023,
there were 18 full meetings of our Board of Directors. All of our directors attended at least 75% of meetings in aggregate of the Board
of Directors and meetings of the committees of which he or she was a member during the year ended December31, 2023.
Director Nominees
The biographical information for the directors
in the table immediately above, including (a)their principal occupations and business experience during at least the past five years
and (b)the names of other public companies for which they currently serve, or have served within the past five years, as a director,
and (c)information about each directors specific experience, qualifications, attributes, or skills that led our board of
directors to conclude that such individual should serve as one of our directors, is provided in
Resolutions 3 to 7 - Re-Appointment
of Directors
.
CORPORATE GOVERNANCE
Board Committees
Audit Committee
Our Board of Directors has established a formal standing audit committee.
The current members of our audit committee are Mr.Williams (Chair), Mr.Grissinger, and Mr.Hashad. Our Board of Directors
has determined that Mr.Williams is an audit committee financial expert within the meaning of SEC rulesand regulations.
Each member of the audit committee is independent as defined under applicable rulesof the Nasdaq, including the independence requirements
contemplated by Rule10A-3 under the Exchange Act.
13
The
Board of Directors has adopted a written audit committee charter. The composition and responsibilities of the audit committee and the
attributes of its members, as reflected in its charter, are intended to be in accordance with certain listing requirements of Nasdaq
and the rulesof the SEC for corporate audit committees. The audit committee charter may be found in the Investor Relations
Corporate Governance section of our website, which is located at
http://investor.akaritx.com/
.
The audit committee held four meetings during the year ended December31,
2023.
Compensation Committee
Our compensation committee currently consists of two members, appointed
by the Board of Directors: Mr.Williams (Chair) and Mr.Grissinger, each of whom are independent within the meaning of SEC corporate
governance rulesof independence for purposes of the compensation committee.
The
Board of Directors has adopted a written compensation committee charter. The composition and responsibilities of the compensation committee
and the attributes of its members, as reflected in its charter, are intended to be in accordance with certain listing requirements of
Nasdaq and the rulesof the SEC for corporate compensation committees. The compensation committee charter may be found in the Investor
Relations Corporate Governance section of our website, which is located at
http://investor.akaritx.com/
.
The compensation committee held four meetings during the year ended
December31, 2023.
Nominating and Corporate Governance Committee
Our nominating and corporate governance committee currently consists
of three members, appointed by our Board of Directors: Mr.Williams, Mr.Grissinger (Chair), and Mr.Hashad, all of whom
are independent within the meaning of SEC corporate governance rulesof independence for purposes of the nominating and corporate
governance committee. None of our non-employee directors have any service contracts with us or any of our subsidiaries that provide for
benefits upon termination of employment.
The
Board of Directors has adopted a written nominating and corporate governance committee charter. The composition and responsibilities
of the nominating and corporate governance committee and the attributes of its members, as reflected in its charter, are intended to
be in accordance with certain listing requirements of Nasdaq and the rulesof the SEC for corporate nominating and corporate governance
committees. The nominating and corporate governance committee charter may be found in the Investor Relations Corporate
Governance section of our website, which is located at
http://investor.akaritx.com/
.
The nominating and corporate governance committee held four meetings
during the year ended December31, 2023.
Independence of our Board of Directors
Our securities are listed on the Nasdaq Capital Market, and we use
the standards of independence prescribed by rulesset forth by Nasdaq. Under Nasdaq rules, a majority of a listed companys
board of directors must be comprised of independent directors. In addition, Nasdaq rulesrequire that, subject to specified exceptions,
each member of a listed companys audit committee and compensation committee be independent and satisfy additional independence
criteria set forth in Rules10A-3 and 10C-1, respectively, under the Exchange Act. Under the applicable Nasdaq rules, a director
will only qualify as an independent director if, in the opinion of our Board of Directors, that person does not have a relationship
which would interfere with the exercise of independent judgment in carrying out the responsibilities of a director. Our Board of Directors
determined that each of Dr.Prudo, Mr.Grissinger, Mr.Hashad, and Mr.Williams are independent as defined under applicable
rulesof the Nasdaq, and, in the case of all members of the audit and compensation committees, the independence requirements contemplated
by Rule10A-3 and Rule10C-1 under the Exchange Act. Additionally, the Board of Directors determined that Dr.James Hill,
Dr.Stuart Ungar, and Mr.David Byrne, each of whom served on the Board of Directors until our 2023 Annual Meeting in June2023,
were independent. As Dr.Patel is our Interim President and Chief Executive Officer, he is not independent. Ms.Jacques, who
served as our former Chief Executive Officer and as a director until May2024, is also not independent.
14
Board Diversity
We believe that it is important that the Board
of Directors reflects the diversity of employees, and the communities that we serve. Diversity includes race, ethnicity, age, and gender
and is also broadly construed to take into consideration many other factors, including industry knowledge, operational experience, scientific
and academic expertise and personal backgrounds. The composition of our Board of Directors currently includes 1 individual who is diverse
under the Nasdaq listing rule5604(f)regarding board diversity, as presented in the below Board Diversity Matrix. Under the
Nasdaq listing rule5604(f), directors who self-identify as (i)female, (ii)an underrepresented minority, or (iii)LGBTQ+
are defined as being diverse. Information about each individual director and director nominee is set forth above.
Board Diversity Matrix (As of May
24
, 2024)
Total Number of Directors
5
Female
Male
Non-Binary
Did Not
Disclose
Gender
PartI: Gender Identity
Directors
5
PartII: Demographic Background
African American or Black
Alaskan Native or Native American
Asian
Hispanic or Latinx
Native Hawaiian or Pacific Islander
White
4
Two or More Races or Ethnicities
1
LGBTQ+
Did Not Disclose Demographic Background
Boards Role in Risk Oversight
Our Board of Directors oversees the management
of risks inherent in the operation of our business and the implementation of our business strategies. Our Board of Directors performs
this oversight role by using several different levels of review. In connection with its reviews of our operations and corporate functions,
our Board of Directors addresses the primary risks associated with those operations and corporate functions. In addition, our Board of
Directors reviews the risks associated with our business strategies periodically throughout the year as part of its consideration of undertaking
any such business strategies.
Each of our board committees also oversees the
management of our risk that falls within the committees areas of responsibility. In performing this function, each committee has
full access to management, as well as the ability to engage advisors. Our Principal Financial Officer reports to the audit committee and
is responsible for identifying, evaluating and implementing risk management controls and methodologies to address any identified risks.
In connection with its risk management role, our audit committee meets privately with representatives from our independent registered
public accounting firm and our Principal Financial Officer. The audit committee oversees the operation of our risk management program,
including the identification of the primary risks associated with our business and periodic updates to such risks, and reports to our
Board of Directors regarding these activities.
15
Code of Business Conduct and Ethics
We
have adopted a written code of business conduct and ethics that applies to our principal executive officer (PEO), principal
financial officer, principal accounting officer or controller, or persons performing similar functions. We have posted a current copy
of the Code of Business Conduct and Ethics in the Investor Relations Corporate Governance section of our website,
which is located at
http://investor.akaritx.com/
. We intend to satisfy the disclosure requirements under Item 5.05 of Form8-K
regarding an amendment to, or waiver from, a provision of our code of business conduct and ethics by posting such information on our
website at
www.akaritx.com
.
Insider Trading Policy, Pledging and Hedging of Company Stock
Certain transactions in our securities (such as
purchases and sales of publicly traded put and call options, and short sales) could create a heightened compliance risk or the appearance
of misalignment between management and shareholders. In addition, securities held in a margin account or pledged as collateral may be
sold without consent if the owner fails to meet a margin call or defaults on the loan, thus creating the risk that a sale may occur at
a time when an officer or director is aware of material, non-public information or otherwise is not permitted to trade in Company securities.
We believe it is improper and inappropriate for Company personnel to engage in short-term or speculative transactions involving the Companys
securities and therefore the Companys insider trading policy states that our personnel and any related persons not engage in specific
types of activities, including but not limited to, short sales, the placement of any standing or limit orders on the Companys securities,
use of the Companys securities to secure a margin or other loan, transactions in straddles, collars or other similar risk reduction
or hedging devices, and transactions in publicly-traded options relating to the Companys securities, except, in each case, under
limited circumstances and with prior approval of our policy administrator.
Director Nomination Process
The process followed by our nominating and corporate
governance committee to identify and evaluate director candidates includes requests to board members and others for recommendations, including
through the use of search firms or other advisors, meetings from time to time to evaluate biographical information and background material
relating to potential candidates, and interviews of selected candidates by management, recruiters, members of the committee and our Board
of Directors.
Once candidates have been identified, the nominating
and corporate governance committee confirms that the candidates meet all of the minimum qualifications for director nominees established
by the nominating and corporate governance committee. The nominating and corporate governance committee may gather information about the
candidates through interviews, detailed questionnaires, comprehensive background checks or any other means that the nominating and corporate
governance committee deems to be appropriate in the evaluation process. The nominating and corporate governance committee then meets as
a group to discuss and evaluate the qualities and skills of each candidate, both on an individual basis and taking into account the overall
composition and needs of our Board of Directors. Based on the results of the evaluation process, the nominating and corporate governance
committee recommends candidates for the Board of Directors approval to fill a vacancy or as director nominees for election to the
Board of Directors by our shareholders each year in the class of directors whose term expires at the relevant annual general meeting.
We have no formal policy regarding board diversity.
Our priority in selection of board members is identification of members who will further the interests of our shareholders through consideration
of a number of facts and circumstances, including among other things, the skills of the prospective director candidate, his or her depth
and breadth of business experience or other background characteristics, his or her independence and the needs of the Board of Directors.
Shareholder Recommendations and Nominees
Our nominating and corporate governance committee considers both recommendations
and nominations for candidates to the Board of Directors from shareholders so long as such recommendations and nominations comply with
our Articles of Association and applicable laws, including the rulesand regulations of the SEC. Shareholders may recommend director
nominees for consideration by the nominating and corporate governance committee by writing to our Company Secretary at the address below,
or the Companys registered office address from time to time, and providing evidence of the shareholders ownership of our
ordinary shares and/or ADSs, the nominees name, home and business address, as well as the nominees detailed biographical
data and qualifications for board membership, and information regarding any arrangements or understandings between the shareholder and
the recommended candidate.
17
Following verification of the shareholder status
of the person submitting the recommendation, all properly submitted recommendations will be promptly brought to the attention of the nominating
and corporate governance committee. Shareholders who desire to nominate persons directly for election to the Board of Directors at an
annual general meeting of shareholders must meet the deadlines and other requirements set forth under Additional Information-Shareholder
Resolutions for 2025 Annual General Meeting. Any vacancies on the Board of Directors occurring between our annual general meetings
of shareholders may be filled by persons selected by a majority of the directors then in office, in which case any director so elected
will serve until the next annual general meeting of shareholders when such director will offer himself/herself for re-appointment, or
by persons elected by an ordinary resolution of the shareholders of the Company.
You may write to the nominating and corporate
governance committee at:
Joe Carroll
Company Secretary
Akari Therapeutics, Plc
Highdown House
Yeoman Way, Worthing
West Sussex BN99 3HH
Director Attendance at Annual General Meeting of Shareholders
Directors are expected to try to attend our annual
general meeting of shareholders to the extent practicable.
Two directors attended our 2023 Annual General
Meeting in person and one director attended remotely.
Shareholder Communication with the Board of Directors
Any interested party with concerns about our Company
may report such concerns to the Board of Directors or the chairman of our Board of Directors and nominating and corporate governance committee.
Communications may be addressed to the entire Board of Directors or to any individual director. All such communications will initially
be received and processed by our Company Secretary. Spam, junk mail, advertisements and threatening, hostile, illegal and similar unsuitable
communications will not be delivered to the Board of Directors. Shareholders can contact members of the Board of Directors by writing
care of our Company Secretary at the Companys registered office address at Highdown House, Yeoman Way, Worthing, West Sussex BN99
3HH.
A copy of any such written communication may also
be forwarded to our external legal counsel and a copy of such communication may be retained for a reasonable period of time. The director
may discuss the matter with our legal counsel, with independent advisors, with non-management directors, or with our management, or may
take other action or no action as the director determines in good faith, using reasonable judgment, and applying his or her own discretion.
Communications may be forwarded to other directors
if they relate to important substantive matters and include suggestions or comments that may be important for other directors to know.
In general, communications relating to corporate governance and long-term corporate strategy are more likely to be forwarded than communications
relating to ordinary business affairs, personal grievances, and matters as to which we tend to receive repetitive or duplicative communications.
The audit committee oversees the procedures for the receipt, retention,
and treatment of complaints received by us regarding accounting, internal accounting controls, or audit matters, and the confidential,
anonymous submission by employees of concerns regarding questionable accounting, internal accounting controls or auditing matters. We
have also established a toll-free telephone number for the reporting of such activity, which is 844-440-0028.
18
SECURITY
OWNERSHIP OF CERTAIN
BENEFICIAL OWNERS AND MANAGEMENT
The following table sets forth, as of May24, 2024 (except as
otherwise indicated below), information we know about the beneficial ownership of our ordinary shares by:
●
each person or entity, including any group as that term is used in Section13(d)(3)of the Exchange Act, who
is known by us to own beneficially more than 5% of the issued and outstanding shares of our common stock;
●
each of our current directors and director nominees;
●
each of our NEOs, as set forth in the Summary Compensation Table set forth below;
●
all of our current directors and executive officers as a group.
We have determined beneficial ownership in accordance with the rulesof
the SEC, and the information in the table below is not necessarily indicative of beneficial ownership for any other purpose. The SEC has
defined beneficial ownership of a security to mean the possession, directly or indirectly, of voting power and/or investment
power. In computing the percentage ownership of each person, ordinary shares subject to options, warrants, or rights held by that person
that are currently exercisable, or exercisable within 60 days of May24, 2024, are deemed to be outstanding and beneficially owned
by that person. These shares, however, are not deemed outstanding for the purpose of computing the percentage ownership of any other person.
To our knowledge and except as indicated in the notes to this table
and pursuant to applicable community property laws, each shareholder named in the table has sole voting and investment power with respect
to the shares set forth opposite such shareholders name. The percentage of ownership is based on 15,847,391,523 ordinary shares
issued and outstanding on May24, 2024. All fractional share amounts have been rounded to the nearest whole number. To our knowledge,
except as noted below, no person or entity is the beneficial owner of more than 5% of the voting power of the Companys ordinary
shares.
Number of
Percentage of
Ordinary Shares
Ordinary Shares
Beneficially
Beneficially
Name and Address of Beneficial Owner(1)
Owned(2)
Owned
5% Shareholders:
Raymond Prudo-Chlebosz and Affiliates
3,494,957,900
(4
)
21.6
%
PranaBio Investments LLC
2,608,678,167
(5
)
16.0
%
RPC Pharma Limited (3)
809,977,100
(6
)
5.1
%
Named Executive Officers and Directors:
Rachelle Jacques
397,563,063
(7
)
2.5
%
Wendy F. DiCicco
5,000,000
(8
)
*
Wael Hashad
5,000,000
(8
)
*
Samir Patel
2,608,678,167
(9
)
16.0
%
Raymond Prudo-Chlebosz
3,494,957,900
(10
)
21.6
%
Michael Grissinger
36,500,000
(11
)
*
Donald Williams
39,850,000
(12
)
*
All current directors and executive officers as a group (6 individuals)
6,587,549,129
(13
)
38.9
%
*
Denotes less than 1% beneficial owner.
(1)Except as otherwise noted, the address for each person listed
above is c/o Akari Therapeutics, Plc, 22 Boston Wharf Road FL 7, Boston, MA 02210.
(2)Our shareholders, NEOs and directors may hold ordinary shares,
ADS or a combination of both. This column shows each holders beneficial ownership assuming all shares were held as ordinary shares,
which may not be the case. Our ADSs are listed on The Nasdaq Capital Market under the trading symbol AKTX. Ordinary shares
are convertible to ADSs at a 2,000 to one ratio.
19
(3)The principal business office of RPC Pharma Limited is c/o
Landmark Fiduciare (Suisse) SA, 6 Place des Eaux-Vives, P.O.Box 3461, Geneva, V8 1211, Switzerland.
(4)Based on the Amendment No.7 Schedule 13D filed with
the SEC on January4, 2024 by RPC Pharma Limited (RPC), together with Raymond Prudo-Chlebosz, M.D. and Praxis Trustees
Limited as trustee of The Sonic Healthcare Holding Company (Praxis, and together with Raymond Prudo-Chlebosz and RPC, Raymond
Prudo-Chlebosz and Affiliates) in which Dr.Prudo reported sole voting power with respect to 2,636,271,200 shares, shared
voting power with respect to 3,484,957,900 shares, sole dispositive power with respect to 2,636,271,200 shares, and shared dispositive
power with respect to 3,484,957,900 shares as of January4, 2024. In his individual capacity, Dr.Prudo beneficially owns the
3,484,957,900 Ordinary Shares (inclusive of 304,690,600 and 9,210,500 Ordinary Shares issuable upon exercise of warrants held by Dr.Prudo
and RPC Pharma, respectively). RPC beneficially owns the 809,977,100 Ordinary Shares (inclusive of 9,210,500 Ordinary Shares issuable
upon exercise of warrants). Praxis beneficially owns 38,709,600 Ordinary Shares. Voting and investment decisions with respect to shares
owned by RPC and Praxis are controlled by Dr.Prudo. Additionally, includes 10,000,000 ordinary shares underlying outstanding stock
options that are exercisable within 60 days of May24, 2024 held by Dr.Prudo.
(5)Based on the Form3 filed with the SEC on January2,
2024 by Samir Patel, principal of PranaBio Investments, LLC, and information provided by Dr.Patel. Consists of (i)2,085,237,500
ordinary shares, (ii)prefunded warrants exercisable to purchase 96,774,000 ordinary shares (represented by 48,387 ADSs) at an exercise
price of $0.0001 per ordinary share (or $0.20 per ADS), (iii)warrants exercisable to purchase 425,000,000 ordinary shares (represented
by 212,500 ADSs) at exercise prices ranging from $0.0016 to $0.03 per ordinary share (or $17.00 to $60.00 per ADS), and (iv)1,666,667
ordinary shares underlying outstanding stock options that are exercisable within 60 days of May24, 2024.
(6)Based on the Amendment No.7 Schedule 13D filed with
the SEC on January4, 2024 by RPC, together with Ray Prudo, M.D. and Praxis in which RPC reported sole voting power with respect
to 0 shares, shared voting power with respect to 809,977,100 shares, sole dispositive power with respect to 0 shares, and shared dispositive
power with respect to 809,977,100 shares as of January4, 2024. Voting and investment decisions with respect to shares owned by RPC
are controlled by Dr.Prudo.
(7)Consists of (i)155,187,375 ordinary shares held by Ms.Jacques,
(ii)137,784,677 ordinary shares underlying outstanding stock options that are exercisable within 60 days of March15, 2024,
and (iii)135,427,175 vested RSUs which have not been settled in ordinary shares as of May24, 2024.
(8)Consists of 5,000,000 ordinary shares underlying outstanding
stock options that are exercisable within 60 days of May24, 2024.
(9)Dr.Patel is principal of PranaBio Investments, LLC.
Refer to Note 5.
(10)Refer to Note 4.
(11) Consists of (i)20,000,000 ordinary shares held by Mr.Grissinger,
and (ii)16,500,000 ordinary shares underlying outstanding stock options that are exercisable within 60 days of May24, 2024.
(12) Consists of (i)20,000,000 ordinary shares held by Mr.Williams,
and (ii)19,850,000 ordinary shares underlying outstanding stock options that are exercisable within 60 days of May24, 2024.
(13) Includes (i)195,801,354 ordinary shares underlying outstanding
stock options that are exercisable within 60 days of May24, 2024, (ii)135,427,175 vested RSUs which have not been settled
in ordinary shares as of May24, 2024, (iii)prefunded warrants exercisable to purchase 96,774,000 ordinary shares, and (iv)warrants
exercisable to purchase 738,901,100, which are held by our directors and NEOs as a group.
CERTAIN RELATIONSHIPS AND TRANSACTIONS WITH
RELATED PERSONS
Since January1, 2022, we have not entered into or engaged in
any related party transactions, as defined by the SEC, with our directors, officers, and shareholders who beneficially owned more than
5% of our outstanding ordinary shares (5% holders), as well as affiliates or immediate family members of those directors,
officers, and 5% holders, except with respect to the transactions described below.
The Doctors Laboratory
The Company leases office space for its U.K. headquarters in London
from The Doctors Laboratory (TDL) and has incurred expenses of approximately $0.1 million plus VAT during each of the years
ended December31, 2023 and 2022, respectively. David Byrne, a former non-employee director of the Company, is the Chief Executive
Officer of TDL and Dr.Raymond Prudo-Chlebosz, the Companys Chairman, is the non-Executive Chairman of the Board of Directors
of TDL.
20
The Company received certain laboratory testing services for its clinical
trials provided by TDL, including certain administrative services, and incurred expenses of approximately $0.1 million during each of
the years ended December31, 2023 and 2022.
Other
Mr.Grissinger began providing business development consulting
services in January2018. The consulting agreement was terminated in November2022. The Company incurred less than $0.1 million
in expenses during the year ended December31, 2022. No such expenses were incurred during the year ended December31, 2023.
We have also entered into certain agreements with our executive officers.
For more information regarding these agreements,seeEmployment Agreements with Our NEOs.
Policies and Procedures for Related Person Transactions
Our Board of Directors is committed to upholding the highest legal
and ethical conduct in fulfilling its responsibilities and recognizes that related party transactions can present a heightened risk of
potential or actual conflicts of interest. Accordingly, as a general matter, it is our preference to avoid related party transactions.
In accordance with our audit committee charter, members of the audit
committee, all of whom are independent directors, review and approve all related party transactions for which approval is required under
applicable laws or regulations, including SEC and the Nasdaq Listing Rules. Current SEC rulesdefine a related party transaction
for smaller reporting companies to include any transaction, arrangement, or relationship in which we are a participant and the amount
involved is the lesser of $120,000 or 1% of total assets, and in which any of the following persons has or will have a direct or indirect
interest:
●
our executive officers, directors, or director nominees;
●
any person who is known to be the beneficial owner of more than 5% of our common stock
●
any person who is an immediate family member, as defined under Item 404 of Regulation S-K, of any of our executive officers, directors,
or director nominees or beneficial owners of more than 5% of our common stock; or
●
any firm, corporation, or other entity in which any of the foregoing persons is employed or is a partner or principal or in a similar
position or in which such person, together with any other of the foregoing persons, has a 5% or greater beneficial ownership interest.
Under our code of business conduct and ethics, our directors, officers,
and employees are expected to avoid any relationship, influence or activity that would cause or even appear to cause a conflict of interest.
Under our code of business conduct and ethics, a director is required to promptly disclose to our Board of Directors any potential or
actual conflict of interest involving him or her. In accordance with our code of business conduct and ethics, the Board of Directors will
determine an appropriate resolution on a case-by-case basis. All directors must recuse themselves from anydiscussion or decision
affecting their personal, business, or professional interests. In addition, the audit committee is responsible for reviewing with our
primary counsel the results of their review of the monitoring of compliance with our code of business conduct and ethics.
DIRECTOR COMPENSATION
Directors who are also employees are not compensated separately for
serving on our Board of Directors or any of its committees. Each of our non-employee directors receives cash compensation for his or her
services. In addition, to better align the interests of our Board of Directors with our shareholders, the compensation committee considers
and recommends to the Board of Directors long-term equity compensation in the form of stock options to our non-employee directors. The
compensation committee periodically conducts reviews of peer company director compensation practices, including before considering changes
to our director compensation program.
21
Under our director compensation program, each director receives an
annual cash retainer for service on the Board of Directors and for service on each committee of which the director is a member. The chairperson
of each committee receives a higher retainer for such service. These fees are typically paid quarterly in arrears, with the exception
of the Chairman of the Board of Directors who is paid monthly. The fees paid to non-employee directors for service on the board and for
service on each committee of the Board of Directors on which the director was a member during 2023 were as follows:
Member
Annual Fee
Chairperson
Annual Fee
Board of Directors
$
41,305
$
100,000
Audit Committee
$
7,875
$
18,375
Compensation Committee
$
5,570
$
11,139
Nominating and Corporate Governance Committee
$
5,570
$
11,139
A non-employee director may elect to receive annual cash payments in
the form of fully-vested ordinary shares. During 2023, no director elected to receive his or her annual cash retainer in shares.
Directors typically receive an initial grant of an option to purchase
5,000,000 ordinary shares (or 10,000,000 ordinary shares for the non-executive chairman) or equivalent value of ADSs, upon being appointed
to the Board of Directors and on the date of each annual general meeting. The Board of Directors reserves the discretion to review and
amend this amount.
These awards typically vest in full on the date of the next annual
general meeting following the date of grant, subject to the non-employee directors continued service on the Board of Directors
through such date, have a term of 10 years from date of grant, and accelerate upon a change of control.
The following table below sets forth information for the fiscal year
ended December31, 2023 regarding the compensation of our non-employee directors.
Fees Earned
or Paid
in Cash
($)(1)
Option
Awards
($)(2)
Total
($)
Raymond Prudo-Chlebosz, M.D. (3)
100,000
13,000
113,000
Michael Grissinger
60,350
6,500
66,850
Wael Hashad (4)
28,684
6,500
35,184
Samir R. Patel, M.D.(5)
3,704
6,103
9,807
Donald Williams
65,280
6,500
71,780
David Byrne (6)
49,170
-
49,170
James Hill (6)
29,343
-
29,343
Stuart Ungar (6)
23,645
-
23,645
(1)Represents cash fees earned for service as a non-employee
director for 2023.
(2)Represents the aggregate grant date fair value of option awards
made to each listed director in 2023, as computed in accordance with FASB ASC Topic 718, disregarding estimated forfeitures related to
service-based vesting. See Note 6 to the financial statements included elsewhere in this Annual Report on Form10-K regarding assumptions
we made in determining the fair value of option awards. As of December31, 2023, our non-employee directors held options to purchase
our ordinary shares as follows: Dr.Prudo: 10,000,000 shares; Mr.Grissinger: 16,500,000 shares; Mr.Hashad: 5,000,000
shares; Dr.Patel: 5,000,000 shares; and Mr.Williams: 19,850,000 shares. Messrs.Byrne, Hill, and Ungar did not hold any
outstanding options as of December31, 2023.
22
(3)Dr.Prudo served as our Executive Chairman from September2015
through December2022. Effective January1, 2023. Dr.Prudo began serving as the Chairman of our Board of Directors with
a renumeration package of $100,000 per annum, paid in equal monthly installments.
(4)Mr.Hashad was appointed to our Board of Directors effective
June30, 2023, at our 2023 annual general meeting. Mr.Hashad has served as a member of our audit committee and nominating and
corporate governance committee since June30, 2023.
(5)Dr.Patel was appointed to our Board of Directors effective
November29, 2023. Dr.Patel has served as a member of our compensation committee until his appointment as the Companys
Interim President and Chief Executive Officer.
(6)This individual served as a director until our 2023 annual
general meeting on June30, 2023.
EXECUTIVE OFFICERS OF THE COMPANY
Our currently-serving executive officers, their
respective ages, positions, background and qualifications, as of May24, 2024 are described below. Our executive officers serve until
they resign, or the Board of Directors terminates their position. There are no family relationships between any of our executive officers,
and there is no arrangement or understanding between any executive officer and any other person pursuant to which the executive officer
was selected.
Name
Age
Position
Samir R. Patel, M.D.*
55
Interim President and CEO
Wendy DiCicco
56
Interim Chief Financial Officer
* Dr.Patel is a member of our Board of Directors. See Information
about our Directors above for more information about Dr.Patel.
Wendy
DiCicco
has served as our Interim Chief Financial Officer since July2023. Ms.DiCicco has more than
25 years of experience in the life sciences industry, currently serving as a board member or as an independent financial and board advisor
to companies, often in the role of interim Chief Financial Officer (CFO).
Ms.DiCicco served as CFO for Renovacor,Inc., a pre-clinical
biopharmaceutical company developing a gene therapy for cardiovascular disease from September2019 to December2022. Initially
as interim CFO, then transitioning to permanent, she led the company through its business combination with Chardan Healthcare Acquisition
2 Corp. in 2021 and sale to Rocket Pharmaceuticals in December2022. She also served as interim CFO for FerGene,Inc., a Phase
3 urologic oncology gene therapy company, from January2020 through May2022. Previously, from August2017 to October2018,
she was CFO and Chief Operating Officer (COO) of Centinel Spine and the President and COO of Camber Spine, from November2014
to July2017, both developers of best-in-class spinal implants. She has held CFO roles for several pre-IPO, private equity backed
medical device and biotechnology companies, in varying stages of commercialization. Her first CFO role was with Kensey Nash Corporation,
a publicly traded developer and manufacturer of biologics and medical devices in the cardiovascular and orthopedics industries, where
she advanced the company from a pre-revenue IPO stage to approximately $100 million in global revenue across multiple product platforms.
Her career started in public accounting at Deloitte Touche.
Ms.DiCicco currently serves on the board of directors of EyePoint
Pharmaceuticals,Inc., a publicly traded company, where she also serves as the audit committee chair. In addition, she serves on
the board of Imvax,Inc. Ms.DiCicco has also served on the boards of SWK Holdings Corp.,II-VI,Inc (now Coherent
Corp.), Sincerus Pharmaceuticals, Carmell Therapeutics, SynCardia Systems and CannaPharma Rx.
Ms.DiCicco received a B.S. in accounting from Philadelphia College
of Textiles and Science and is a licensed Certified Public Accountant. She also is an appointed Board Leadership Fellow and Corporate
Governance Fellow of the National Association of Corporate Directors.
23
NAMED EXECUTIVE OFFICER COMPENSATION
The following table provides information regarding the total compensation
awarded to, earned by, and paid to our NEOs for services rendered to us in all capacities for the fiscal years indicated.
2023 Summary Compensation Table
This section discusses the material components of the Companys
executive compensation program for our NEOs for the fiscal year ended December31, 2023:
●
Rachelle Jacques, Former President and Chief Executive Officer
●
Wendy DiCicco,Interim Chief Financial Officer
●
Torsten Hombeck, Former Chief Financial Officer
Summary Compensation Table
The following table sets forth information concerning the compensation
of our NEOs during the fiscal years ended December31, 2023 and 2022:
Name and Principal
Position
Year
Salary
($)
Bonus
($)
Stock
Awards
(S)(4)
Option
Awards
($)(5)
All
Other
Compensation
($)(6)
Total
($)
Rachelle Jacques(1)
2023
615,750
-
729,393
198,498
16,500
1,560,141
Former President and Chief Executive Officer
2022
458,333
875,000
253,410
1,965,991
49,865
3,602,599
Wendy DiCicco(2)
2023
226,184
45,000
-
6,480
-
277,664
Interim Chief Financial Officer
Torsten Hombeck(3)
2023
138,945
-
-
-
28,561
167,506
Former Chief Financial Officer
2022
300,150
72,036
-
32,448
44,111
448,745
(1)Pursuant to notice provided the Company on April25,
2024, Rachelle Jacques stepped down as the President and Chief Executive Officer of the Company, effective May1, 2024 and on May7,
2024, Ms.Jacques resigned from the Board of Directors.
(2)Ms.DiCicco was appointed as the Companys Interim
Chief Financial Officer on July17, 2023.
(3)Dr.Hombeck served as the Companys Chief Financial
Officer until June15, 2023.
(4)Represents the aggregate grant date fair value of time-based
restricted stock units (RSUs) issued under our 2014 Equity Incentive Plan (the 2014 Plan) and 2023 Equity
Incentive Plan (the 2023 Plan), as computed in accordance with Financial Accounting Standards Board (FASB)
Accounting Standards Codification (ASC) Topic 718, disregarding estimated forfeitures related to service-based vesting.
See Note 6 to our consolidated financial statements included elsewhere in this Annual Report on Form10-K regarding assumptions we
made in determining the fair value of RSUs.
(5)Represents the aggregate grant date fair value of options
to purchase ordinary shares issued under our 2014 Plan and 2023 Plan, as computed in accordance with FASB ASC Topic 718, disregarding
estimated forfeitures related to service-based vesting. See Note 6 to our consolidated financial statements included elsewhere in this
Annual Report on Form10-K regarding assumptions we made in determining the fair value of option awards.
(6)For 2023, all other compensation includes the following amounts:
Name
Company
401(k)
Plan Match
Other(a)
Total
Ms.Jacques
16,500
-
16,500
Ms.DiCicco
-
-
-
Dr.Hombeck
11,461
17,100
28,561
(a)Amounts reported as Other in the table above
represent earned and unused vacation paid to Dr.Hombeck upon termination of his employment with us.
24
Narrative Disclosure to Summary Compensation Table
Employment Agreements with Our NEOs
We have entered into employment agreements with each of our NEOs (or
non-employee consulting services agreements in the case of Ms.DiCicco). All employee NEOs are at-will employees.
Rachelle Jacques Employment Agreement
Prior to her departure, effective May2024, we were party to an
executive employment agreement, effective February28, 2022, with Ms.Jacques, our former President and Chief Executive Officer
(the Jacques Agreement). Pursuant to the Jacques Agreement, Ms.Jacquess initial annual base salary was $600,000,
which was subject to review and increase on an annual basis and she was eligible to receive an annual cash bonus with a target of 50%
of base salary based on the achievement of performance goals established by the Chairman of the Board of Directors and the full Board
of Directors, in consultation with Ms.Jacques. Under the terms of the Jacques Agreement, Ms.Jacques received a cash signing
bonus of $650,000 in connection with her hire. Ms.Jacques was required to repay us 50% of the signing bonus if, prior to the first
anniversary of her start date, her employment was terminated by us for cause (as defined in the Jacques Agreement) or by
her without good reason (as defined in the Jacques Agreement) and she was required to repay us one-third of the signing
bonus if her employment was terminated by us for cause or by her without good reason after the first anniversary but prior to the second
anniversary of her start date. In addition, the Jacques Agreement provided for the following RSU awards: (i)RSUs having a face value
of $262,000 within 75 days of her start date, which vested 50% on the first anniversary of the start date and monthly thereafter for the
following year, (ii)RSUs having a value of $446,000 on the first anniversary of her start date, which vested 50% on the second anniversary
of the start date and monthly thereafter for the following year, and (iii)RSUs having a value of $446,000 on the second anniversary
of her start date, which would have vested 50% on the third anniversary of the start date and monthly thereafter for the following year.
Such RSU grants are subject to full acceleration in the event of a change in control (as defined in the Jacques Agreement),
involuntary termination of employment without cause, resignation for good reason, or termination of employment due to death or disability
(as defined in the Jacques Agreement). In the event that any change in control, involuntary termination of employment without cause, resignation
for good reason, or termination of employment due to death or disability occurs prior to any such grant, the Company is obligated to pay
Ms.Jacques a lump sum in cash equal to the face value of the ungranted RSU award. The Jacques Agreement further provided that the
Company would grant Ms.Jacques an option to purchase 237,396,700 ordinary shares, subject to ratable vesting on a semiannual basis
over four years from her start date. Commencing with annual long-term incentive awards to senior executives in 2023, in addition to the
RSU and option awards described above, the Jacques Agreement provided that Ms.Jacques would be eligible to receive awards under
the Companys equity incentive plan not less frequently than annually with a target grant value of not less than 100% of Ms.Jacquess
annual base salary for fiscal year 2023 and thereafter otherwise commensurate with awards to executives at similarly situated companies
as recommended by a reputable compensation consultant engaged by the Board of Directors.
Upon termination of Ms.Jacquess employment due to Ms.Jacquess
death or disability, Ms.Jacques or her estate or beneficiaries would be entitled to receive (i)a pro-rated portion of the
annual bonus, if any, that she would have otherwise earned for the year in which the employment terminates had no termination occurred
(the Pro-Rata Bonus).
Upon termination of Ms.Jacquess employment by us without
cause, or by Ms.Jacques for good reason, subject to her compliance with the confidentiality provisions of the Jacques Agreement
and her execution and the effectiveness of a release of claims in favor of the Company and its affiliates in a form provided by the Company
(the Release), Ms.Jacques would be entitled to receive (i)a lump sum payment equal to the sum of the annual
base salary and target annual performance bonus in effect for the year in which the date of termination occurs (the Cash Severance),
(ii)any earned but unpaid annual bonus for the previous year, (iii)the Pro-Rata Bonus, and (iv)provided she timely and
properly elects COBRA coverage, reimbursement for the monthly COBRA premium paid by Ms.Jacques for her and her eligible dependents
until the earliest of (x)12 months following the date of termination, (y)the date on which she is no longer eligible to receive
such coverage, and (z)the date on which Ms.Jacques becomes eligible to receive similar coverage from another employer or other
source (the COBRA Reimbursement). In addition, if Ms.Jacques agrees in writing that the non-competition restrictions
in the Jacques Agreement shall continue to apply following the termination of her employment, (i)all outstanding equity-based compensation
awards that do not vestbased on the attainment of performance goals shall fully vest, and (ii)all outstanding equity-based
compensation awards that vest based on the attainment of performance goals shall remain outstanding and eligible to vest based on attainment
of the applicable performance goals.
25
In the event of a termination of Ms.Jacquess employment
by us without cause (other than on account of death or disability), or by Ms.Jacques for good reason, in each case within 18 months
following a change in control, and subject to her compliance with the cooperation, confidentiality, restrictive covenants, and proprietary
rights provisions of the Jacques Agreement and her execution and the effectiveness of a Release, in lieu of the severance payments and
benefits described in the preceding paragraph, she is entitled to receive (i)the Cash Severance, (ii)a lump sum payment equal
to her target bonus for the year in which the date of termination occurs (or the year in which the change in control occurs, if higher)
and (iii)the COBRA Reimbursement. In addition, if Ms.Jacques agrees in writing that the non-competition restrictions in the
Jacques Agreement will continue to apply following the termination of her employment, (i)all outstanding unvested stock options
held by her will become fully vested and will remain exercisable for the remainder of their original term and (ii)all outstanding
equity-based awards other than stock options that do not vest based on the attainment of performance goals will fully vest. If the payments
or benefits payable to Ms.Jacques in connection with a change in control would be subject to the excise tax on golden parachutes
imposed under Section4999 of the Internal Revenue Code of 1986, as amended (the Code), those payments or benefits
will be reduced if such reduction would result in a higher net after-tax benefit to Ms.Jacques.
The employment agreement also contains restrictive covenants for the
Companys benefit and Ms.Jacques is required to maintain the confidentiality of our confidential information.
Pursuant to notice provided on April25, 2024, Ms.Jacques
stepped down as our President and Chief
Executive Officer, effective May1, 2024. The terms of Ms.Jacquess
separation are still being finalized and
are therefore not yet available for disclosure hereunder.
Wendy DiCicco Consulting Services Agreements
We are a party to a consulting services agreement, dated January15,
2024, with an entity controlled by Ms.DiCicco (the DiCicco Agreement). The DiCicco Agreement provides for a $40,000
per month fee for services up to 80 hours per month, paid in two equal installments on the 15th and 30th date of each month in which services
are rendered and reimbursement of certain expenses. Any time exceeding 80 hours per month requires advance approval by the CEO. The DiCicco
Agreement expires on May31, 2024, provided, however, either party may terminate the DiCicco Agreement at any time without cause
on 30 days prior written notice or with cause on five days prior written notice.
Prior to entering into the DiCicco Agreement, the Company was party
to a consulting services agreement, dated July17, 2023, and amended on September1, 2023 (as amended, the Original DiCicco
Agreement), with an entity controlled by Ms.DiCicco. The Original DiCicco Agreement had a six month term and provided for
a $32,000 per month fee, which was increased to $40,000 effective September1, 2023, a performance bonus in an amount of up to $70,000
upon achievement of certain milestones, and reimbursement of certain expenses. The Original DiCicco Agreement also provided that Ms.DiCicco
would be granted an initial option to purchase 5,000,000 ordinary shares. If we terminate Ms.DiCiccos engagement for any
reason other than for cause prior to the date that such option is fully vested, the option will continue to vest through July17,
2024 or be accelerated, at our option.
On April26, 2024, the Company entered into Amendment No.2
to the DiCicco Agreement (the DiCicco Amendment). The DiCicco Amendment provides for (i)a $40,000 per month fee (the
Consulting Base Pay) for services up to 80 hours per month, paid in two equal installments on the 15th and 30th date of
each month in which services are rendered and reimbursement of certain expenses; (ii)a 2024 target bonus percentage of 45% of the
Consulting Base Pay; (iii)a transaction bonus of 10% of the Consulting Base Pay upon the successful closing of the planned merger
between the Company and Peak Bio Inc.; (iv)a one-time grant of restricted stock units (RSUs) on May1, 2024 totaling
1% of the Companys outstanding ordinary shares, which shall vest in full on May1, 2025, subject to Ms.DiCiccos
continued service to the Company, and (v)a severance payment to Ms.DiCicco in the event the Company terminates employment
without cause.
26
The DiCicco Agreement also contains restrictive covenants for our benefit
and Ms.DiCicco is required to maintain the confidentiality of our confidential information.
Hombeck Employment Agreement
Prior to his resignation in June2023, we were party to an executive
employment agreement, effective as of June30, 2020, with Dr.Hombeck (the Hombeck Agreement). The Hombeck Agreement
had an initial term of one year from June30, 2020 with automatic renewals for successive one-year periods, provided that either
party could have given written notice of non-renewal of the current term at least three months prior to the expiration of the then-current
term.
Dr.Hombecks annual base salary for 2023 was $303,152 and
he was eligible for an annual cash bonus with a target of 30% of base salary. The Hombeck Agreement also provided that Dr.Hombeck
would be granted an initial option to purchase 7,000,000 shares and an additional option to purchase 3,000,000 shares on January1,
2021.
Pursuant to the Hombeck Agreement, upon termination of Dr.Hombecks
employment without cause (as defined in the Hombeck Agreement), or by Dr.Hombeck for good reason (as
defined in the Hombeck Agreement) or upon non-renewal by the Company of the term of the Hombeck Agreement, in addition to any accrued
but unpaid base salary, expense reimbursements and vested and accrued benefits and subject to Dr.Hombecks execution and the
effectiveness of a release of claims in a form acceptable to the Company, he would have been entitled to receive (i)an amount equal
to the sum of (x)his annual base salary at the rate in effect as of the termination date, plus (y)other than in the case of
a termination due to non-renewal of the term, an amount equal to the greater of his actual or target annual performance bonus for the
year in which the employment terminated and (ii)an amount equal to the Companys share of the premium paid by Dr.Hombeck
while he was an active employee for medical insurance coverage under the Companys health care plan (the Healthcare Subsidy)
for 12 months following termination.
If Dr.Hombecks employment had been terminated by us without
cause, or by him for good reason, in each case with one year following a change in control (as defined in the Hombeck Agreement),
and subject to Dr.Hombecks execution and the effectiveness of a release of claims in a form acceptable to the Company, in
lieu of the severance payments and benefits described in the preceding paragraph, he would have been entitled to receive (i)an amount
equal to one and a half times the sum of (x)his annual base salary at the rate in effect as of the termination date, plus (y)his
target annual performance bonus for the year in which the employment terminated and (ii)the Healthcare Subsidy for 18 months following
termination. If the payments or benefits payable to Dr.Hombeck in connection with a change in control would have been subject to
the excise tax on golden parachutes imposed under Section4999 of the Code, those payments or benefits would have been reduced if
such reduction would result in a higher net after-tax benefit to Dr.Hombeck.
Dr.Hombeck is also subject to restrictive covenants for our benefit,
including a requirement to maintain the confidentiality of our confidential information.
Determining Compensation
Our Board of Directors and compensation committee review compensation
annually for our executives. In setting executive base salaries and bonuses and granting equity incentive awards, we consider compensation
for comparable positions in the market, the historical compensation of our executives, individual performance as compared to our expectations
and objectives, our desire to motivate our employees to achieve short- and long-term results that are in the best interests of our shareholders,
and a long-term commitment to our Company.
Our compensation committee is primarily responsible for determining
the compensation for our executive officers. Our compensation committee typically reviews and discusses managements proposed compensation
with our Chief Executive Officer for all executives other than the Chief Executive Officer. Based on those discussions and its discretion,
taking into account the factors noted above, the compensation committee then sets the compensation for each executive officer other than
the Chief Executive Officer and recommends the compensation for the Chief Executive Officer to our Board of Directors for approval. Our
Board of Directors discusses the compensation committees recommendation and ultimately approves the compensation of our Chief Executive
Officer without members of management present.
27
In 2023, our compensation committee utilized the services of Amplify
Strategy Consulting LLC (Amplify), an independent compensation consultant. During 2023, Amplify did not provide
material services to us other than the services to our compensation committee. Based on its evaluation, our compensation committee has
determined that Amplifys work has not raised any conflict of interests. In 2023, we paid Amplify $12,000 related to the design
of long-term incentive plans for executives and non-executives.
Elements of Compensation
The compensation of our NEOs generally consists
of three primary components, consisting of base salary, annual cash incentive awards, and long-term incentive-based compensation in the
form of stock-based awards.
Base Salary
Prior to her departure in May2024, Ms.Jacques received
an annual salary of $615,750 and, prior to his departure in June2023, Dr.Hombeck received an annual salary of $303,152. Ms.DiCicco
is a non-employee consultant and received a monthly fee of $32,000 from July17, 2023 through August31, 2023 and a monthly
fee of $40,000 from September1, 2023 through December31, 2023.
Annual Cash Incentives
Annual cash incentive awards provide an opportunity for additional
compensation to employee NEOs if pre-established annual performance goals are attained. The annual cash incentive award targets are based
on a target percentage of each employee NEOs salary. The compensation committee generally links cash awards to the achievement
of the annual corporate goals; however, the compensation committee may take into consideration unexpected corporate performance outside
of the corporate goals and individual performance. The amount of the bonus paid, if any, may vary among the employee NEOs depending on
individual performance, individual contribution to the achievement of our annual corporate goals.
Annual cash incentive awards for 2023 for employees, including our
NEOs, were based on corporate goals related to financing, pipeline advancement, reputation, and strengthening our capabilities. For 2023,
the annual cash incentive award for Ms.Jacques was targeted at 50% of base salary and the annual cash incentive award for Dr.Hombeck
was targeted at 30% of his base salary. However, Dr.Hombeck was not eligible to receive an incentive bonus because his employment
terminated in July2023. After reviewing Company performance against the corporate goals, the compensation committee determined not
to award cash bonuses to the employee NEOs for the year ended December31, 2023.
Pursuant to the Original DiCicco Agreement, Ms.DiCicco was eligible
for performance bonuses in the aggregate amount of $70,000 upon achievement of certain milestones, including (i)$25,000 upon achievement
of a specified guaranteed cash flow target by August23, 2023 (Milestone 1), (ii)$25,000 upon resolving NASDAQ
non-compliance on minimum bid price and shareholders equity by October23, 2023 (Milestone 2), and (iii)$20,0000
upon achievement of internal finance capability improvements by December31, 2023 (Milestone 3). Ms.DiCicco received
total bonuses of $45,000 for 2023 in light of achievement of Milestone 2 and Milestone 3.
Equity-Based Awards
Equity grants are intended as both a reward for contributing to our
long-term success and an incentive for future performance. Additionally, the vesting feature of our equity awards is intended to further
our goal of executive retention by providing an incentive to our NEOs to remain in our service during the vesting period. The compensation
committee typically makes initial stock option awards to our employee NEOs upon commencement of employment and annual equity awards in
the form of either stock options, RSUs, or a combination of stock options and RSUs, thereafter.
28
In 2023, we awarded equity compensation under the 2014 Plan and/or
the 2023 Plan to Ms.Jacques and Ms.DiCicco in the form of time-vesting stock options and/or time-based RSUs. We determine
equity award amounts based on contractual obligations, competitive market factors in our industry, and the judgment of the compensation
committee of the Board of Directors, taking into account information and recommendations provided by our independent compensation consultant.
With respect to our NEOs other than our Chief Executive Officer, the compensation committee also considers recommendations provided
by our Chief Executive Officer. For the 2023 awards of stock options and RSUs to our NEOs, the primary consideration was the award amounts
included in the applicable NEOs employment and/or consulting services agreements.
Other Compensation and Benefits
We have established various employee benefit plans,
including medical and 401(k)plans, in which employee NEOs are eligible to participate on the same basis as other employees. It is
generally our policy not to extend perquisites to our executives that are not available to our employees generally.
401(k)Plan and Defined Contribution Pension
Scheme
We have adopted an employee benefit plan under Section401(k)of
the Code for our U.S.-based employees. The 401(k)plan allows employees to make salary deferral contributions up to the statutorily
prescribed annual limit under the Code. We provide matching contributions to the 401(k)plan in an amount equal to 100% of each participants
contribution up to a maximum of 5% of the participants annual eligible cash compensation, subject to certain other limits.
Additionally, we have adopted a defined contribution pension scheme
which allows for U.K.-based employees to make salary deferral contributions and we contribute 10% of employee compensation to the pension
plan, subject to U.K. law.
Clawback Policy
In November2023, our compensation committee adopted a formal
clawback policy, which applies in the event we are required to prepare an accounting restatement due to any material noncompliance with
any financial reporting requirement under the U.S. federal securities laws. This policy requires us to (subject to certain limited exceptions
set forth in the clawback policy and permitted under the final clawback rules) recover from any of our current or former executive officers
who receive incentive-based compensation (including stock options and RSUs) after the effective date of the clawback policy and during
the three-year period preceding the date on which we are required to prepare an accounting restatement, the excess of what would have
been paid to such executive officer under the accounting restatement.
Compensation Committee Interlocks and Insider
Participation
None of the members of our compensation committee
has at any time during the prior three years been one of our officers or employees. None of our executive officers currently serves, or
in the past fiscal year has served, as a member of the Board of Directors or compensation committee of any entity that has one or more
executive officers serving on our Board of Directors or compensation committee.
29
Outstanding Equity Awards at 2023 Fiscal Year-End
The following table sets forth information regarding the outstanding
equity held by our NEOs as of December31, 2023.
Option Awards
Stock Awards
Name
Number of Securities
Underlying
Unexercised Options
(#) Exercisable
Number of Securities
Underlying
Unexercised Options
(#) Unexercisable
Option
Exercise
Price
($)
Option
Expiration Date
Number of Shares,
Units or Other
Rights that have Not
Vested
(#)
Market or Payout
Value of Shares,
Units or Other
Rights Not Vested
($)(1)
Rachelle Jacques
77,862,900
129,771,500
(2)
0.0124
6/1/2032
11,160,863
18,601,438
(3)
0.0124
7/29/2032
19,086,338
133,604,363
(4)
0.0016
6/1/2033
5,368,900
(5)
8,375
189,787,200
(6)
296,068
190,798,825
(7)
297,646
Wendy DiCicco
-
5,000,000
(8)
0.0013
7/17/2033
Torsten Hombeck(9)
(1)Market Value is calculated based on a price per ADS of $3.12
(equivalent to $0.00156 per ordinary share), which was the closing price of our ADSs on December29, 2023, the last trading day of
2023.
(2)Represents the unvested portion of a stock option award that
vests in five equal installments of 25,954,300 ordinary shares on each of March28, 2024, September28, 2024, March28,
2025, September28, 2025, and March28, 2026, subject to Ms.Jacquess continued employment with us through the applicable
vesting date.
(3)Represents the unvested portion of a stock option award that
vests in five equal installments of 3,720,288 ordinary shares on each of March28, 2024, September28, 2024, March28,
2025, September28, 2025, and March28, 2026, subject to Ms.Jacquess continued employment with us through the applicable
vesting date.
(4)Represents the unvested portion of a stock option award that
vests in seven equal installments of 19,086,338 ordinary shares on each of June1, 2024, December1, 2024, June1, 2025,
December1, 2025, June1, 2026, December1, 2026, and June1, 2027, subject to Ms.Jacquess continued
employment with us through the applicable vesting date.
(5)Represents the unvested portion of time-based RSUs granted
on June1, 2022 that vest in equal monthly installments over the six-month period beginning on January1, 2024 and ending on
June1, 2024, subject to Ms.Jacquess continued employment with us through the applicable vesting date.
(6)Represents the unvested portion of time-based RSUs granted
on March28, 2023 that vest 50% on March28, 2024, with the remainder vesting in 12 equal monthly installments thereafter, subject
to Ms.Jacquess continued employment with us through the applicable vesting date.
(7)Represents the unvested portion of time-based RSUs granted
on June30, 2023 that vest in seven equal installments of 27,256,975 ordinary shares on each of June30, 2024, December31,
2024, June30, 2025, December31, 2025, June30, 2026, December31, 2026, and June30, 2027, subject to Ms.Jacquess
continued employment with us through the applicable vesting date.
(8)Represents the unvested portion of a stock option award that
vests 100% on July17, 2024, subject to Ms.DiCiccos continued service to us through the vesting date.
(9)All options (vested and unvested) previously held by Dr.Hombeck
were either forfeited as of, or expired subsequent to, the date of Dr.Hombecks termination of employment with us on June30,
2023.
Pay Versus Performance Disclosure
In accordance with rulesadopted by the Securities and Exchange
Commission pursuant to the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010, we provide the following disclosure regarding
executive compensation for our PEOs and Non-PEO NEOs and certain Company financial performance measures for the fiscal years listed below.
The disclosure included in this section is prescribed by SEC rulesand does not necessarily align with how the Company or the compensation
committee view the link between the Companys performance and NEO compensation.
30
Year
Summary
Compensation
Table Total
for PEO 1
1
($)
Summary
Compensation
Table Total
for PEO 2
($)
Compensation
Actually Paid
to PEO 1
1,2,3
($)
Compensation
Actually Paid
to PEO 2
1,2,3
($)
Average
Summary
Compensation
Table Total
for Non-PEO
NEOs
1
($)
Average
Compensation
Actually Paid
to Non-PEO
NEOs
1,2,3
($)
Value
of
Initial
Fixed $100
Investment
based on:
4
TSR
($)
Net
Income
($ Millions)
2023
1,560,141
N/A
979,796
N/A
222,585
192,449
10.40
(10.0)
2022
3,602,599
1,093,134
2,034,587
1,088,479
533,372
526,893
31.33
(17.7)
1.
Rachelle Jacques was our PEO from March28, 2022 to May1, 2024 (PEO 1). Clive Richardson was our PEO until
March28, 2022 (PEO 2). Our Non-PEO NEOs for each year presented are listed below.
2022
2023
Torsten Hombeck
Torsten Hombeck
Ray Prudo
Wendy DiCicco
2. The amounts shown for Compensation Actually Paid have been calculated
in accordance with Item 402(v)of Regulation S-K and do not reflect compensation actually earned, realized, or received by the Companys
NEOs. These amounts reflect the Summary Compensation Table Total for the PEOs and the Average Summary Compensation Totals for the Non-PEO
NEOs with certain adjustments as described in footnote 3 below.
3. Compensation Actually Paid reflects the exclusions and inclusions
of certain amounts from the Summary Compensation Table Totals for the PEOs and the average for the Non-PEO NEOs as set forth below. Equity
values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the
totals from the Stock Awards and Option Awards columns of the Summary Compensation Table.
Year
Summary
Compensation
Table Total
for PEO 1
($)
Exclusion
of Stock
Awards and
Option
Awards
for
PEO 1
($)
Inclusion of
Equity
Values for
PEO 1
($)
Compensation
Actually Paid
to PEO 1
($)
2023
1,560,141
(927,891)
347,546
979,796
2022
3,602,599
(2,219,401)
651,389
2,034,587
Year
Summary
Compensation
Table Total
for PEO 2
($)
Exclusion
of Stock
Awards and
Option
Awards for
PEO 2
($)
Inclusion of
Equity
Values for
PEO 2
($)
Compensation
Actually
Paid
to PEO 2
($)
2022
1,093,134
(4,655)
1,088,479
31
Year
Average
Summary
Compensation
Table Total
for Non-PEO
NEOs
($)
Average
Exclusion
of Stock
Awards and
Option
Awards for
Non-PEO
NEOs
($)
Average
Inclusion of
Equity
Values for
Non-PEO
NEOs
($)
Average
Compensation
Actually Paid to
Non-PEO
NEOs
($)
2023
222,585
(3,240)
(26,896)
192,449
2022
533,372
(16,224)
9,745
526,893
The amounts in the Inclusion of Equity Values or Average Inclusion
of Equity Values, as applicable, in the tables above are derived from the amounts set forth in the following tables:
Year
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested
as of Last
Day of
Year for
PEO1
($)
Change in
Fair Value
from Last
Day of
Prior Year
to Last
Day of
Year of
Unvested
Equity
Awards
for PEO1
($)
Vesting-
Date Fair
Value of
Equity
Awards
Granted
During
Year that
Vested
During
Year for
PEO1
($)
Change in
Fair Value
from Last
Day of
Prior Year
to Vesting
Date of
Equity
Awards
that
Vested
During
Year for
PEO1
($)
Fair Value
at Last
Day of
Prior Year
of Equity
Awards
Forfeited
During
Year for
PEO1
($)
Total - Inclusion
of
Equity
Values for PEO1
($)
2023
741,153
(305,976)
63,708
(151,339)
347,546
2022
556,323
95,066
651,389
Year
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested
as of Last
Day of
Year for
PEO2
($)
Change
in
Fair Value
from Last
Day of
Prior Year
to Last
Day of
Year of
Unvested
Equity
Awards
for PEO2
($)
Vesting-
Date Fair
Value of
Equity
Awards
Granted
During
Year that
Vested
During
Year for
PEO2
($)
Change
in
Fair Value
from Last
Day of
Prior Year
to Vesting
Date of
Equity
Awards
that
Vested
During
Year for
PEO2
($)
Fair
Value
at Last
Day of
Prior Year
of Equity
Awards
Forfeited
During
Year for
PEO2
($)
Total
- Inclusion
of
Equity
Values for PEO2
($)
2022
(4,655)
(4,655)
32
Year
Average Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for Non-PEO NEOs
($)
Average Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards for Non-PEO NEOs
($)
Average Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year for Non-PEO NEOs
($)
Average Change in Fair Value from Last Day of Prior Year to Vesting Date of Equity Awards that Vested During Year for Non-PEO NEOs
($)
Average Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year for Non-PEO NEOs
($)
Total - Average Inclusion of
Equity Values for Non-PEO NEOs
($)
2023
2,771
(1)
(1,624)
(28,042)
(26,896)
2022
29,987
(14,931)
(5,311)
9,745
4. Assumes $100 was invested in the Company for the period starting
December31, 2021 through the end of the listed year. Historical stock performance is not necessarily indicative of future stock
performance.
33
Description of Relationship Between PEOs and Non-PEO NEO Compensation
Actually Paid and Company Total Shareholder Return (TSR)
The following chart sets forth the relationship between Compensation
Actually Paid to our PEOs, the average of Compensation Actually Paid to our Non-PEO NEOs, and the Companys cumulative TSR over
the two most recently completed fiscal years.
34
Description of Relationship Between PEOs and Non-PEO NEO Compensation
Actually Paid and Net Income
The following chart sets forth the relationship between Compensation
Actually Paid to our PEOs, the average of Compensation Actually Paid to our Non-PEO NEOs, and our net income during the two most recently
completed fiscal years.
AUDIT COMMITTEE REPORT
The audit committee oversees the Companys
accounting and financial reporting processes and the audits of the Companys financial statements, evaluates auditor performance,
manages relations with the Companys independent registered public accounting firm and evaluates policies and procedures relating
to internal control systems. The audit committee operates under a written audit committee charter that has been adopted by the Board of
Directors of the Company. All members of the audit committee currently meet the independence and qualification standards for audit committee
membership set forth in the listing standards provided by Nasdaq and the SEC, and the Board of Directors has determined that Mr.Williams
is an audit committee financial expert, as the SEC has defined that term in Item 407 of Regulation S-K.
The audit committee members are not professional
accountants or auditors. The members functions are not intended to duplicate or to certify the activities of management and the
independent registered public accounting firm. The audit committee serves a board-level oversight role in which it provides advice, counsel
and direction to management and the auditors on the basis of the information it receives, discussions with management and the auditors,
and the experience of the audit committees members in business, financial and accounting matters.
The audit committee oversees the Companys
financial reporting process on behalf of the Board of Directors. The Companys management has the primary responsibility for the
financial statements and reporting process, including the Companys system of internal controls. In fulfilling its oversight responsibilities,
the audit committee reviewed with management the audited consolidated financial statements included in the Annual Report on Form10-K
for the financial year ended December31, 2023. This review included a discussion of the quality and the acceptability of the Companys
financial reporting, including the nature and extent of disclosures in the financial statements and the accompanying notes.
35
The audit committee also reviewed with BDO USA,
P.C. (BDO), our independent registered public accounting firm, which is responsible for expressing an opinion on the conformity
of the audited financial statements with accounting principles generally accepted in the United States of America, their judgments as
to the quality and the acceptability of the Companys financial reporting and such other matters as are required to be discussed
with the Committee by Public Company Accounting Oversight Board (PCAOB) Auditing Standard No.1301,
Communications
with Audit Committees
, and SEC Regulation S-X Rule207,
Communication with Audit Committees
.
The audit committee has received the written disclosures
and the letter from BDO required by the applicable requirements of the PCAOB regarding communications with the audit committee concerning
independence. The audit committee has discussed with BDO its independence from management and the Company.
In addition to the matters specified above, the
audit committee discussed with BDO the overall scope, plans and estimated costs of their audit. The Committee met with BDO periodically,
with and without management present, to discuss the results of BDOs examinations, the overall quality of the Companys financial
reporting and BDOs reviews of the quarterly financial statements, and drafts of the quarterly and annual reports.
In reliance on the reviews and discussions referred
to above, and subject to the limitations of the audit committees role and responsibilities referred to above and in the audit committee
charter, the audit committee recommended to the Board of Directors that the Companys audited consolidated financial statements
should be included in the Companys Annual Report on Form10-K for the financial year ended December31, 2023.
The Audit Committee of the Board of Directors
Donald Williams, Chairperson
Michael Grissinger
Wael Hashad
The foregoing report of the audit committee
shall not be deemed incorporated by reference by any general statement incorporating by reference this Proxy Statement into any filing
under the Securities Act of 1933, as amended, or under the Securities Exchange Act of 1934, as amended, except to the extent that the
Company specifically incorporates this information by reference, and shall not otherwise be deemed filed under such acts.
DELIVERY OF PROXY MATERIALS
Our Annual Report on Form10-K accompanies
this Proxy Statement. Copies of our Annual Report and the exhibits thereto are available from the Company without charge upon written
request of a shareholder. Copies of these materials are also available online through the SEC at
www.sec.gov
. The Company may satisfy
SEC rulesregarding delivery of proxy materials, including this Proxy Statement and our Annual Report, by delivering a single set
of proxy materials to an address shared by two or more Company shareholders or ADS holders, a practice known as householding.
This delivery method can result in meaningful cost savings for the Company. In order to take advantage of this opportunity, the Company
may deliver only a single set of proxy materials to multiple shareholders or ADS holders who share an address, unless contrary instructions
are received prior to the mailing date. Similarly, if you share an address with another shareholder or ADS holder and have received multiple
copies of our proxy materials, you may write or call us at the address and phone number below to request delivery of a single copy of
the proxy materials in the future. We undertake to deliver promptly upon written or oral request a separate copy of the proxy materials,
as requested, to a shareholder or ADS holders at a shared address to which a single copy of the proxy materials was delivered. If you
are an ordinary shareholder of record and prefer to receive separate copies of proxy materials either now or in the future, please contact
Joe Carroll, Company Secretary, by mail at Akari Therapeutics, Plc, Highdown House, Yeoman Way, Worthing, West Sussex BN99 3HH or by telephone
at +1 (929) 274-7511. If you hold ADSs and you prefer to receive separate copies of proxy materials either now or in the future, please
contact our depositary, Deutsche Bank, or your brokerage firm or bank, as applicable.
36
EACH SHAREHOLDER IS URGED TO COMPLETE, DATE,
SIGN
AND PROMPTLY RETURN THE ENCLOSED FORMOF PROXY.
EACH ADS HOLDER IS URGED TO COMPLETE, DATE, SIGN AND PROMPTLY RETURN
THE ADS PROXY CARD TO DEUTSCHE BANK, THE DEPOSITARY FOR THE ADSs.
ADDITIONAL INFORMATION
U.K. Statutory Annual Accounts and Reports of the Board of Directors
and Auditors of Akari Therapeutics, Plc for the financial year ended December31, 2023
Consistent with its obligations under the U.K.
Companies Act 2006, our Board of Directors will present at the AGM our U.K. statutory annual accounts and reports for the financial year
ended December31, 2023, which have been approved by and, where appropriate, signed on behalf of our Board of Directors and will
be delivered to the Registrar of Companies in the United Kingdom following the AGM. A copy of our U.K. statutory directors remuneration
report, including the annual report on remuneration, is included as Annex A to this Proxy Statement. A complete copy of our U.K. statutory
annual accounts and reports, including the statutory Board of Directors report, strategic report, and auditors report on our U.K.
accounts will be sent separately to you no less than 21 days prior to the AGM. You will be provided an opportunity to raise questions
in relation to such accounts and reports at the AGM. Full accounts and reports will be available for inspection prior to and during the
AGM.
Shareholders Rights to Call a General Meeting
Our shareholders have the right to call a meeting
of our shareholders. The U.K. Companies Act 2006 generally requires the directors to call a general meeting once we have received requests
to do so from shareholders representing at least 5% of our paid-up shares entitled to vote at a general meeting. The U.K. Companies Act
2006 generally prohibits shareholders of a U.K. public limited company from passing written resolutions. However, significant shareholders
would, in any case, still have the power to call a general meeting and propose resolutions. These provisions are mandatory under the U.K.
Companies Act 2006 and cannot be waived by our shareholders.
Shareholder Resolutions for 2025 Annual General Meeting
Pursuant to Rule14a-8 under the Exchange
Act, in order to be considered for inclusion in our Proxy Statement for our 2025 annual general meeting of shareholders, shareholder resolutions
must be received by the Company at the office of the Company Secretary, Highdown House, Yeoman Way, Worthing, West Sussex BN99 3HH no
later than 120 days before the anniversary of the date on which we sent our proxy materials for the AGM, or February2, 2025. However,
if the date of such annual general meeting is more than 30 calendar days from the date of the anniversary of the AGM, then the notice
must be received by our Company Secretary a reasonable time before we begin to print and send our proxy materials.
If a shareholder wishes to present a proposal
at an annual general meeting but does not wish to have the proposal considered for inclusion in our Proxy Statement and proxy card, such
shareholder proposal must be received by the Company at the office of the Company Secretary, Highdown House, Yeoman Way, Worthing, West
Sussex BN99 3HH no later than 45 days before the anniversary of the date on which the Company first mailed its proxy materials for the
prior years annual general meeting, or no later than April19, 2025. To comply with the universal proxy rules, shareholders
who intend to solicit proxies in support of director nominees other than the Companys nominees must provide notice that sets forth
the information required by Rule14a-19 under the Exchange Act, no later than April28, 2025.
However, if the date of the annual general meeting is changed by more than 30 calendar days from the date of the anniversary of the prior
years annual general meeting, the notice must be received by our Company Secretary within a reasonable time before we begin to
print and send our proxy materials with respect to such annual general meeting. If a shareholder does not timely provide notice as described
above, proxies solicited on behalf of our management for such annual general meeting will confer discretionary authority to vote with
respect to any such matter, as permitted by the proxy rulesof the SEC.
Under section 338 of the U.K. Companies Act 2006,
shareholders representing at least 5% of holders entitled to vote on a resolution at an annual general meeting may require the Company
to include such resolution in its notice of an annual general meeting. Provided the applicable thresholds are met, notice of the resolution
must be received by the Company at the office of the Company Secretary, Highdown House, Yeoman Way, Worthing, West Sussex BN99 3HH at
least six weeks prior to the date of the annual general meeting, or, if later, at the time notice of the annual general meeting is delivered
to shareholders.
37
Shareholder Rights
Under section 527 of the U.K. Companies Act 2006,
members meeting the threshold requirement set out in that section have the right to require us to publish on a website a statement setting
out any matter relating to: (i)the audit of our accounts (including the auditors report and the conduct of the audit) that
are to be laid before the AGM; or (ii)any circumstance connected with our auditor ceasing to hold office since the previous meeting
at which annual accounts or reports were laid in accordance with section 437 of the U.K. Companies Act 2006. We may not require the shareholders
requesting any such website publication to pay our expenses in complying with sections 527 or 528 of the U.K. Companies Act 2006. Where
we are required to place a statement on a website under section 527 of the U.K. Companies Act 2006, we must forward the statement to our
auditor not later than the time when we make the statement available on the website. The business which must be dealt with at the AGM
includes any statement that we have been required, under section 527 of the U.K. Companies Act 2006, to publish on a website.
Householding
The SEC has adopted rulesthat permit companies
and intermediaries (e.g., brokers) to satisfy the delivery requirements for proxy materials with respect to two or more shareholders sharing
the same address by delivering a single set of proxy materials addressed to those shareholders. This process, which is commonly referred
to as householding, potentially means extra convenience for shareholders and cost savings for companies.
This year, a number of brokers with account holders
who are our shareholders will be householding the proxy materials. A single set of proxy materials will be delivered to
multiple shareholders sharing an address unless contrary instructions have been received from the affected shareholders. Once you have
received notice from your broker that they will be householding communications to your address, householding
will continue until you are notified otherwise or until you revoke your consent. If, at any time, you no longer wish to participate in
householding and would prefer to receive a separate set of proxy materials, please notify your broker or us. Direct your
written request to Akari Therapeutics, Plc, Highdown House, Yeoman Way, Worthing, West Sussex BN99 3HH, Attn: Joe Carroll, Company Secretary.
Shareholders who currently receive multiple copies of the proxy materials at their addresses and would like to request householding
of their communications should contact their brokers.
Questions?
If you have any questions or need more information
about the AGM please write to us at:
Joe Carroll
Company Secretary
Akari Therapeutics, Plc
Highdown House
Yeoman Way, Worthing
West Sussex BN99 3HH
38
ANNEX A
AKARI THERAPEUTICS, PLC
BOARD OF DIRECTORS REMUNERATION REPORT
FOR THE PERIOD ENDED 31 DECEMBER 2023
ANNUAL STATEMENT FROM THE CHAIR OF THE COMPENSATION
COMMITTEE
[See Attached]
39
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT
FOR THE YEAR ENDED 31 DECEMBER 2023
PARTI - ANNUAL REPORT ON REMUNERATION
Single Total Figure of Remuneration for Each Director
The following table shows the compensation paid or accrued during
the fiscal year ended 31 December2023.
Name
of
Director
Salary
and/or Fees
($)
Other
compensation
($)
Bonus
($)
RSU
Awards
($)(1)
Option
Awards
($)(2)
Pension
Benefits
($)(3)
2023
Total ($)
2023
Total
Fixed ($)
2023
Total
variable ($)
Executive
Director
Rachelle
Jacques
615,750
-
-
729,393
198,498
16,500
1,560,141
615,750
945,391
Non-Executive
Director
Ray
Prudo, M.D.(4)
100,000
-
-
-
13,000
-
113,000
100,000
13,000
Michael
Grissinger
60,350
-
-
-
6,500
-
66,850
60,350
6,500
Samir
Patel, M.D(5)
3,704
-
-
-
6,103
-
9,807
3,704
6,103
Mohamed
Wael Ahmed Hashad(6)
28,684
-
-
-
6,500
-
35,184
28,684
6,500
Donald
Williams
65,280
-
-
-
6,500
-
71,780
65,280
6,500
James
Hill, M.D.(7)
29,343
-
-
-
-
-
29,343
29,343
-
Stuart
Ungar, M.D.(7)
23,645
-
-
-
-
-
23,645
23,645
-
David
Byrne(7)
49,170
-
-
-
-
-
49,170
49,170
-
(1)Represents the aggregate grant date
fair value of time-based restricted stock units (RSUs) issued under our 2014 Equity Incentive Plan (the 2014 Plan)
and/or 2023 Equity Incentive Plan (the 2023 Plan) in accordance with IFRS 2, Share-based payment.
(2)Represents the aggregate grant date
fair value of options to purchase ordinary shares issued under our 2014 Plan and/or 2023 Plan in accordance with IFRS 2, Share-based
payment.
(3)Consists of company contributions to
U.K. pension scheme or the U.S. 401k Plan.
(
4)Dr.Prudo
served as our Executive Chairman from September2015 through December2022. Effective January1, 2023. Dr.Prudo
began serving as the Chairman of our board of directors with a renumeration package of $100,000 per annum, paid in equal monthly installments.
(5)Dr.
Patel
was appointed to our board of directors effective November29, 2023. Dr.Patel has served as a member of our compensation committee
since January30, 2024.
(6)Mr.Hashad was appointed to our
board of directors effective June30, 2023, at our 2023 annual general meeting. Mr.Hashad has served as a member of our audit
committee and nominating and corporate governance committee since June30, 2023.
(7)Served as a director until our 2023
annual general meeting on June30, 2023.
40
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
The following table shows the compensation paid or accrued during
the fiscal year ended 31 December2022.
Name
of
Director
Salary
and/or
Fees ($)
Other
Compensation ($)
Bonus
($)(6)
Long-term
Incentive
($)
Option
Awards
($)(1)
Pension
Benefits
($) (4)
2022
Total ($)
2022
Total Fixed ($)
2022
Total
variable ($)
Executive
Director
Ray
Prudo, M.D. (2)
412,000
-
206,000
-
-
-
618,000
412,000
206,000
Rachelle
Jacques (3)
458,333
-
875,000
-
2,799,224
15,250
4,147,808
3,922,808
225,000
Clive
Richardson (7)
118,195
(7)
14,595
(5)
657,764
(7)
-
-
11,819
802,373
144,609
657,764
Non-Executive
Director
James
Hill, M.D.
61,502
-
-
-
20,278
-
81,780
81,780
-
Stuart
Ungar, M.D.
49,064
-
-
-
20,278
-
69,342
69,342
-
David
Byrne
58,332
-
-
-
20,278
-
78,610
78,610
-
Donald
Williams
56,838
-
-
-
20,278
-
77,116
77,116
-
Peter
Feldschreiber (8)
24,974
-
-
-
-
-
24,974
24,974
-
Michael
Grissinger
41,505
-
-
-
20,278
-
61,783
61,783
-
(1)These amounts represent the aggregate
grant date fair value for option awards for fiscal year 2022 computed in accordance with IFRS 2, Share-based payment. A discussion of
the assumptions used in determining grant date fair value may be found in note 16 to the Financial Statements. In addition to her stock
option awards, Ms.Jacques received a restricted stock award whose grant date fair value was $253,410.
(2)Dr.Prudo served as Executive Chairman
of Akaris Board of Directors from September2015 until December2022 and assumed the role of non-executive Chairman
of the Board effective January1, 2023.
(3)Ms.Jacques was appointed our President
and Chief Executive Officer in March2022. Ms.Jacques received a sign-on bonus in the amount of $650,000.
(4)Consists of company contributions to
U.K. pension scheme or the U.S. 401k Plan.
(5)Consists of company contributions to
health benefits of $11,897 and life insurance premiums of $2,698.
(6) Bonuses are awarded on the basis of
an assessment of the overall performance of the executive director concerned, rather than specific measures or targets. In respect of
2022, the annual bonus payment for Mr.Prudo reflects his strong personal performance at a critical time for the business. The 2022
annual bonus payment for Ms.Jacques was based on the Companys performance against Company objectives agreed by the Board.
Ray Prudo and Rachelle Jacques both received annual bonus payments of 100% of their target cash bonuses respectively, of which 100% was
paid in the first quarter of 2023. None of the awards is attributable to share price appreciation and no discretion was exercised because
of share price appreciation or depreciation. Non-executive directors are not eligible to receive bonuses.
(7)Mr.Richardson resigned as Chief
Executive Officer and Chief Operating Officer in March2022. Prior to his resignation, Mr.Richardson received three months
of salary in the amount of $118,000. After his resignation, Mr.Richardson received a cash termination payment of approximately
$658,000. In addition, Mr.Richardson entered into a consulting agreement with the Company in which Mr.Richardson earned approximately
$305,000.
(8)Mr.Feldschreiber resigned from
the Board, effective 3 June2022.
41
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Incentive Plan Awards
Akari
has two compensation plans under which our equity securities are authorized for issuance (the 2014 Equity Incentive Plan and the 2023
Equity Incentive Plan) under which directors receive options to acquire ordinary shares in Akari.
Upon effectiveness of the 2023
Plan Incentive Plan in June2023, no further awards are available to be issued under the 2014 Plan. As of December31, 2023,
the Company had 789,393,500 ordinary shares underlying outstanding equity awards under the 2014 Plan, consisting of stock options and
restricted stock units.
Options and restricted stock units granted during
the fiscal year ended 31 December2023 are as follows:
Name
of Director
Award
Type
Number
of
Awards (1)
Grant
Date
Exercise
Price ($)
Face
Value
($) (2)
Vesting
Date
Expiry
Date
Rachelle
Jacques
RSU
189,787,200
28/03/2023
N/A
358,698
(3)
28/03/2033
Option
152,690,700
01/06/2023
0.0016
245,832
(4)
01/06/2033
RSU
190,798,825
30/06/2023
N/A
324,358
(5)
30/06/2033
Ray
Prudo, M.D.
Option
10,000,000
30/06/2023
0.0017
17,000
(6)
30/06/2033
Michael
Grissinger
Option
5,000,000
30/06/2023
0.0017
8,500
(6)
30/06/2033
Samir
Patel, M.D.
Option
5,000,000
29/12/2023
0.0016
7,800
(6)
29/12/2033
Mohamed
Wael Ahmed Hashad
Option
5,000,000
30/06/2023
0.0017
8,500
(6)
30/06/2033
Donald
Williams
Option
5,000,000
30/06/2023
0.0017
8,500
(6)
30/06/2033
James
Hill, M.D.
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Stuart
Ungar, M.D.
N/A
N/A
N/A
N/A
N/A
N/A
N/A
David
Byrne
N/A
N/A
N/A
N/A
N/A
N/A
N/A
(1)Option and restricted stock unit awards
are subject to time-based vesting conditions without performance measures or targets other than continued service until the date of vesting.
(2)These amounts represent the face value
for options awards, calculated as the number of shares awarded (assuming full vesting) multiplied by the price per share implied by the
market price per ADS, which is equal to the stated exercise price.
(3)The restricted stock unit award vests
50% on the first anniversary date of the date of grant, or 28 March2024, with the remainder vesting in twelve equal monthly installments
thereafter, subject to continued service.
(4)The stock option award vests and becomes
exercisable ratably on a semiannual basis over a four-year period commencing on 01 June2023, subject to continued service.
(5)The stock restricted stock award vests
and becomes exercisable ratably on a semiannual basis over a four-year period commencing on 30 June2023, subject to continued service.
(6)The stock option awards vests
and becomes exercisable on the date of our 2024 Annual General Meeting, or by 30 June2024.
42
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Directors shareholdings
The table below shows, for each director, the
total number of ordinary shares owned (by the director and connected persons), the total number of unvested restricted stock units held,
the total number shares issuable upon exercise of outstanding warrants, and the total number of share options that were held and the
number of share options vested as at 31 December2023. All unvested restricted stock units and share options are subject to time-based
vesting without performance measures or targets other than continued service until the date of vesting. No director exercised any share
options or warrants during the year ended 31 December2023.
Name
of Director
Ordinary
Shares
Owned(1)
Unvested
Restricted Stock
Units
Share
Warrants
Share
Options
Vested
Share
Options
Executive
Director
Ray
Prudo, M.D.(2)
3,171,056,800
-
313,901,100
10,000,000
-
Rachelle
Jacques
152,502,975
385,954,925
-
390,087,400
108,110,100
Non-Executive
Director
Michael
Grissinger
20,000,000
-
-
16,500,000
11,500,000
Samir
Patel, M.D.
(3)
2,085,237,500
-
521,774,000
5,000,000
-
Mohamed
Wael Ahmed Hashad
-
-
-
5,000,000
-
Donald
Williams
20,000,000
-
-
19,850,000
14,850,000
James
Hill, M.D
-
-
-
-
-
Stuart
Ungar, M.D.
-
-
-
-
-
David
Byrne
-
-
-
-
-
(1)Our shareholders, named executive officers
and directors may hold ordinary shares, ADS or a combination of both. This column shows each holders ownership assuming all shares
were held as ordinary shares, which may not be the case. Our ADSs are listed on The Nasdaq Capital Market under the trading symbol AKTX.
Ordinary shares are convertible to ADSs at a 2,000 to one ratio.
(2)Amounts include holdings of RPC Pharma
Limited (RPC), together with Ray Prudo, M.D. and Praxis Trustees Limited as trustee of The Sonic Healthcare Holding Company
(Praxis, and together with Ray Prudo and RPC, Ray Prudo and Affiliates). In his individual capacity, Dr.Prudo
beneficially owns the 3,484,957,900 Ordinary Shares (inclusive of 304,690,600 and 9,210,500 Ordinary Shares issuable upon exercise of
warrants held by Dr.Prudo and RPC Pharma, respectively). RPC beneficially owns 809,977,100 Ordinary Shares (inclusive of 9,210,500
Ordinary Shares issuable upon exercise of warrants). Praxis beneficially owns 38,709,600 Ordinary Shares. Voting and investment decisions
with respect to shares owned by RPC and Praxis are controlled by Dr.Prudo.
(3)Dr.Patel is principal of PranaBio
Investments, LLC. Share warrants held by PranaBio Investments, LLC consists of (i)prefunded warrants exercisable to purchase 96,774,000
ordinary shares (represented by 48,387 ADSs) at an exercise price of $0.0001 per ordinary share (or $0.20 per ADS), and (ii)warrants
exercisable to purchase 425,000,000 ordinary shares (represented by 212,500 ADSs) at exercise prices ranging from $0.0016 to $0.03 per
ordinary share (or $17.00 to $60.00 per ADS).
43
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Illustration of Total Shareholder Return
The following graph compares the cumulative total
shareholder return on Akaris ADSs, each representing 2,000 ordinary shares, with that of the NASDAQ Biotech Index (^NBI) from
the period that Akaris ADSs were publicly traded on The Nasdaq Capital Market through 31 December2023. Akari selected the
NASDAQ Biotech Index because Akaris ADSs trade on The NASDAQ Capital Market and Akari believes this indicates its relative performance
against a group consisting of more similarly situated companies.
44
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Chief Executive Total Remuneration History
The table below sets out total remuneration details for the Chief
Executive Officer.
Period
Single
total
figure of
remuneration
($)
Bonus
($)
Short-term
incentive payout
against
maximum (1)
Option
and
restricted stock
awards ($)
Option
Awards
against
maximum (2)
2023
Rachelle Jacques
615,750
-
-
927,891
(13)
-
2022
Rachelle Jacques (3)
4,147,808
875,000
(3)
2,799,224
(4)
2022
Clive Richardson (5)
802,373
657,764
(5)
-
-
-
2021
Clive Richardson
612,047
206,826
-
-
-
2020
Clive Richardson
503,941
214,960
-
-
-
2019
Clive Richardson (6)
432,408
177,028
-
-
-
2018
(David Solomon) (7)
173,611
-
-
-
-
2017
(Gur Roshwalb and David Solomon) (7)
1,338,253
119,041
(9)
100%
(10)
-
-
2016
(Gur Roshwalb)
581,250
187,500
125%
(11)
-
-
2015
(Gur Roshwalb)
7,306,951
86,625
100%
(12)
6,863,034
-
2014
(Gur Roshwalb)
410,564
-
-
60,564
-
2013
(Gur Roshwalb) (8)
576,389
-
-
173,396
-
(1)
All cash bonuses to Rachelle Jacques and Clive Richardson were awarded
on a discretionary annual basis, except Ms.Jacquess sign-on bonus.
(2)
All options were awarded on a discretionary basis.
(3)
Rachelle Jacques was appointed as Akaris Chief Executive Officer
on 28 March2022. Ms.Jacquess bonus includes a $650,000 sign-on bonus.
(4)
In addition to Ms.Jacquess stock option awards granted during
2022, Ms.Jacques received a restricted stock award whose grant date fair value was
$253,410.
(5)
Mr.Richardson resigned as Akaris Chief Executive Officer
and Chief Operating Officer in March2022. Mr.Richardson received a termination
payment of $657,746.
(6)
Clive Richardson was appointed Interim Chief Executive on 8 May2018
and Chief Executive Officer on 18 July2019.
(7)
Dr.Roshwalb resigned as Akaris Chief Executive Officer on
29 May2017 and David Solomon was appointed as Akaris Chief Executive Officer
on 28 August2017 and resigned 8 May2018.
(8)
Dr.Roshwalb was appointed as Akaris Chief Executive Officer
on 4 March2013.
(9)
Includes a $50,000 signing bonus.
(10)
Bonus was awarded in 2017 but calculated from Dr.Solomons
appointment on 28 August2017.
(11)
Bonus was awarded in 2016 but calculated for a 15-month period from
the date of the acquisition of Volution Immuno Pharmaceutical SA on 18 September2015.
(12)
Bonus was awarded in 2015 but calculated for a 9-month period until
the date of the acquisition of Volution Immuno Pharmaceutical SA on 18 September2015.
(13)
In addition to Ms.Jacquess stock option awards granted
during 2023, Ms.Jacques received a restricted stock awards with a grant date fair value
of $729,393 in the aggregate.
45
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Directors Remuneration Compared to Other Employees
The table below shows the percentage change in remuneration of each
director and the parent companys non-executive directors on a full-time equivalent basis between the year ended 31 December2022
and the year ended 31 December2023.
Change
in Remuneration in year ended 31 December2022 compared with
remuneration in the year ended 31 December2023
Salary
and/or Fees
Taxable
Benefits
Annual
Bonus
Executive
Director
Ray
Prudo, M.D.
-76%(1)
-
-100%
Rachelle
Jacques
34%(2)
-
-100%
Non-Executive
Director
James
Hill, M.D.
-52%(3)
-
-
Stuart
Ungar, M.D.
-52%(3)
-
-
David
Byrne
-16%(3)
-
-
Donald
Williams
15%(4)
-
-
Mohamed
Wael Ahmed Hashad
-
-
-
Michael
Grissinger
45%(5)
-
-
Samir
Patel, M.D.
-
-
-
Other
Employees
1%
-
-100%
(1)Dr.Prudo served as our executive
chairman from 2015 Septemberthrough 2022 December. Effective 1 January2023, Dr.Prudo began serving as the Chairman
of our board of directors with a renumeration package of $100,000 per annum, paid in equal monthly installments.
(2)Rachelle Jacques was appointed as Akaris
Chief Executive Officer on 28 March2022. Accordingly, the increase is primarily due to renumeration during the year ended 31 December2023
being for twelve months versus nine months for the year ended 31 December2022.
(3)
Served
as a director until our 2023 annual general meeting on 30 June2023. Accordingly, the decrease is primarily due to a partial year
of service for the year ended 31 December2023.
(4)
Mr.Williams
was appointed chairman of the compensation committee on 30 June2023 which increased his annual retainer.
(5)
Mr.Grissinger
was appointed to the compensation and audit committees on 1 November2022 and our as chairman of the nominating and governance committee
on 30 June2023 which increased his annual retainer.
46
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Directors Remuneration Compared to Other Employees (continued)
The table below shows the percentage change in remuneration of each
director and the parent companys non-executive directors on a full-time equivalent basis between the year ended 31 December2021
and the year ended 31 December2022.
Change
in Remuneration in year ended 31 December2021 compared with
remuneration in the year ended 31 December2022
Salary
and/or Fees
Taxable
Benefits
Annual
Bonus
Executive
Director
Ray
Prudo, M.D.
0
%
-
0
%
Rachelle
Jacques
(1)
(1)
(1)
Clive
Richardson
-78%
(2)
-3%
-100%
(2)
Non-Executive
Director
James
Hill, M.D.
-
-
-
Stuart
Ungar, M.D.
-
-
-
David
Byrne
-
-
-
Donald
Williams
-
-
-
Peter
Feldschreiber
-
-
-
Michael
Grissinger
-
-
-
Other
Employees
2
%
76
%
-34
%
(1)Rachelle Jacques was appointed as Akaris
Chief Executive Officer on 28 March2022; there is no comparison.
(2)Mr.Richardson resigned as Akaris
Chief Executive Officer and Chief Operating Officer in March2022. Mr.Richardson received three months of salary in 2022;
he did not receive a 2022 bonus.
The table below shows the percentage change in
remuneration of each director and the parent companys non-executive directors on a full-time equivalent basis between the year
ended 31 December2020 and the year ended 31 December2021.
Change
in Remuneration in year ended 31 December2020 compared with
remuneration in the year ended 31 December2021
Salary
and/or Fees
Taxable
Benefits
Annual
Bonus
Executive
Director
Ray
Prudo, M.D.
0
%
-
0
%
Clive
Richardson
4
%
5%
-4%
Non-Executive
Director
James
Hill, M.D.
-
-
-
Stuart
Ungar, M.D.
-
-
-
David
Byrne
-
-
-
Donald
Williams
-
-
-
Peter
Feldschreiber
-
-
-
Michael
Grissinger
-
-
-
Other
Employees
11
%
44
%
25
%
47
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Directors Remuneration Compared to Other Employees (continued)
The table below shows the percentage change in
remuneration of each director and the parent companys non-executive directors on a full-time equivalent basis between the year
ended 31 December2019 and the year ended 31 December2020.
Change
in Remuneration in year ended 31 December2019 compared with
remuneration in the year ended 31 December2020
Salary
and/or Fees
Taxable
Benefits
Annual
Bonus
Executive
Director
Ray
Prudo, M.D.
3
%
-
3
%
Clive
Richardson
17
%
19%
21%
Non-Executive
Director
James
Hill, M.D.
-
-
-
Stuart
Ungar, M.D.
-
-
-
David
Byrne
-
-
-
Donald
Williams
-
-
-
Peter
Feldschreiber
-
-
-
Michael
Grissinger
-
-
-
Other
Employees
23
%
-9
%
8
%
Relative Importance of Cash Position
The following table sets forth the cash amounts
as at 31 December2023 and 31 December2022.
Period
31
December2023
($)
31
December2022
($)
Change
(%)
Cash
3,845,000
13,250,000
(71%)
Implementation of remuneration policy for year ending 31 December2023
Our director remuneration, comprised of annual
cash retainers and equity grants, is administered by our board of directors with the assistance of the compensation committee. The compensation
committee conducts an annual review of director remuneration and makes recommendations to the board with respect thereto.
The shareholders approved our Directors Remuneration
Policy on June30, 2023 to provide a framework for the Directors remuneration packages. In addition, the Company has a non-executive
director remuneration policy, which was amended and restated on November19, 2015, and was subsequently amended on June29,
2016, January26, 2017, January23, 2018, January8, 2019, and on January9, 2020. On February1, 2023, our
board resolved that the annual cash retainers would be increased by 5%, as compared to 2022. As a result, our non-executive directors
were compensated for service on our board of directors as follows in 2023:
¨
an annual retainer for
service on the board of directors of
$41,305;
¨
an annual retainer for
service as a member of the compensation committee and nominating and governance committee of
$5,570;
¨
an annual retainer for
service as a member of the audit committee of
$7,875;
¨
for the chairman of the
compensation committee, and nominating and governance committee, an annual retainer of
$11,139;
¨
for the chairperson of
the audit committee, an annual retainer of
$18,375;
48
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
The following table presents the increases in
compensation (board fees and/or salaries) agreed for the upcoming fiscal year (with the agreed increases for the year ended 31 December2023
presented as comparative information):
Director
31
December
2022
31
December
2023
Increase/
(Decrease)
%(1)
31
December
2023
31
December
2024(2)
Increase/
(Decrease)
%(3)
Executive
Director
Ray
Prudo, M.D.
(4)
$412,000
$100,000
(76
%)
$100,000
$100,000
0
%
Clive
Richardson
(5)
$118,195
-
N/A
N/A
N/A
N/A
Rachelle
Jacques
(6)
$458,333
$615,750
34%
$615,750
$615,750
0%
Non-Executive
Director
Michael
Grissinger
$49,947
$60,350
21%
$60,350
$65,889
9
%
Samir
R. Patel, M.D
(7)
-
$3,704
N/A
$3,704
$46,875(8)
1,166%
Mohamed
Wael Ahmed Hashad
-
$28,684
N/A
$28,684
$57,055
99%
Donald
Williams
$56,838
$65,280
15%
$65,280
$70,819
85
%
James
Hill
$61,502
$29,343
(52%)
$29,343
N/A
N/A
Stuart
Ungar
$49,064
$23,645
(52%)
$23,645
N/A
N/A
David
Byrne
$58,332
$49,170
(16%)
$49,170
N/A
N/A
Peter
Feldschreiber
$24,974
-
N/A
N/A
N/A
N/A
(1)
On February1, 2023, the Compensation
Committee approved a 5% annual retainer increase for our non-executive directors, effective
as of January1, 2023. All directors are eligible to receive reimbursement for reasonable
out-of-pocket expenses incurred in connection with attendance at meetings of our board of
directors, and our non-executive directors are also eligible to receive reimbursement, upon
approval of the board of directors or a committee thereof, for reasonable out-of-pocket expenses
incurred in connection with attendance at various conferences or meetings with our management.
(2)
All figures are estimates. Additional discretionary
bonuses may be awarded in accordance with contractual entitlement and the remuneration policy.
(3)
There were no changes to annual retainers
for our executive and non-executive directors in 2024. Changes represent the timing of appointment
or termination of service on our board, or sub-committee thereof.
(4)
Dr.Prudo served as our executive chairman
from September2015 through December2022. Effective January1, 2023, Dr.Prudo
began serving as the Chairman of our board of directors with a renumeration package of $100,000
per annum, paid in equal monthly installments.
(5)
Mr.Richardson resigned as Chief Executive
Officer and Chief Operating Officer in March2022. His annual base compensation of 382,306
was pro-rated during 2022.
(6)
Ms.Jacques was appointed as our Chief
Executive Officer in March2022. Her annual base compensation of $458,333 for this role
was pro-rated during 2022. Ms.Jacques received an annual base salary of $615,750 until
her departure, effective May1, 2024.
(7)
All figures represent annual board and committee retainers. Dr.Patel
was appointed as a non-executive director on 29 November2023 and eligible for compensation
in accordance with our non-executive director remuneration policy. Dr.Patel will also
be compensated for his services as Interim President and Chief Executive Officer monthly
in the form of restricted stock units (RSUs) with a fair market value of $50,000.
49
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Compensation Committee Approach to Remuneration
Matters
Our board of directors and compensation committee
review compensation annually for our executives. In setting executive base salaries and bonuses and granting equity incentive awards,
we consider compensation for comparable positions in the market, the historical compensation of our executives, individual performance
as compared to our expectations and objectives, our desire to motivate our employees to achieve short- and long-term results that are
in the best interests of our shareholders, and a long-term commitment to our Company.
Our compensation committee is primarily responsible
for determining the compensation for our executive officers. Our compensation committee typically reviews and discusses managements
proposed compensation with our Chief Executive Officer for all executives other than the Chief Executive Officer. Based on those discussions
and its discretion, taking into account the factors noted above, the compensation committee then sets the compensation for each executive
officer other than the Chief Executive Officer and recommends the compensation for the Chief Executive Officer to our board of directors
for approval. Our board of directors discusses the compensation committees recommendation and ultimately approves the compensation
of our Chief Executive Officer without members of management present.
In 2023, our compensation committee utilized
the services of Amplify Strategy Consulting LLC (Amplify), an independent compensation consultant. During 2023,
Amplify did not provide material services to us other than the services to our compensation committee. Based on its evaluation, our compensation
committee has determined that Amplifys work has not raised any conflict of interests.
50
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
PARTII - DIRECTORS
REMUNERATION POLICY
This section provides information about the Directors
Remuneration Policy (the Policy) of Akari. The Policy was approved at the 2023 Annual General Meeting of Shareholders (AGM)
and will remain in effect for a period of three years thereafter, unless changes to the Policy are required earlier and a new Policy
is put to shareholder vote.
The Policy seeks to provide compensation packages
which will attract, motivate, reward and retain an executive team with the right caliber of talent, experience, and skills to lead a
successful future for Akari. Akaris compensation framework is designed to provide a competitive package in comparison to companies
of similar size, complexity, maturity profile and geographic presence. Elements of compensation packages which are subject to performance
conditions as noted in the Policy may include key performance indicators (KPIs), both financial and non-financial, which are an important
component of the information needed to explain a companys progress towards its stated goals. Other elements which are not subject
to performance measures are considered an important component of attracting and retaining UK resident employees, including Executive
Directors.
The table below sets out the main elements of
the Policy for its Executive Directors and seeks to explain how each element of the compensation package operates:
Policy Table Executive Directors
Element
Purpose
and
Link to Strategy
Operation
Maximum
Opportunity
Performance
Metrics
and Recovery Provisions
Base
Salary
Support
the recruitment and retention of Executive Officers
Base
salary levels are set taking into account the role, responsibilities and individuals
experience in the position, performance of the individual and Akari. Market competitiveness
within the Companys peer benchmarks are utilized to price a job.
Base
salaries are typically reviewed annually.
There
is no prescribed maximum increase nor any requirement to increase salary at any time. The
Company uses established salary ranges for annual merit increases
By
exception, higher increases may be made to reflect individual circumstances. These may include significant changes in the job size
or complexity and/or promotion.
None,
although overall performance of the individual is considered when setting and reviewing salaries.
No
provisions for recovery or withholding of sums as this is not performance-related.
Pension
and other retirement plans
Encourages
and enables executives to build savings for their retirement
Akari
typically makes contributions to pension plans (or retirement savings plans) to match prevailing local market practices.
Currently
up to 10% of salary per annum.
None.
No
provisions for recovery or withholding of sums as this is not performance-related.
Other
Benefits
Provide
market competitive benefits in a cost-effective way
Provisions
include medical insurance, life assurance, permanent health insurance,etc.
In
exceptional circumstances, such as the relocation of an executive or for a new hire, additional benefits may be provided in the form
of relocation allowance and benefits.
Other
benefits may be offered if considered appropriate and reasonable by the Compensation Committee.
No
prescribed maximum.The cost of benefits will vary from year to year in accordance with the cost of insuring such benefits.
None.
No
provisions for recovery or withholding of sums as this is not performance-related.
51
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Element
Purpose
and
Link to Strategy
Operation
Maximum
Opportunity
Performance
Metrics
and Recovery Provisions
Bonus
To
reward the delivery of annual targets as well as to recogniseindividual contributions towards our key strategic achievements
Any
bonus is paid in cash typically within 60 days after the end of the financial year to which
it relates.
Performance
objectives and targets are either fixed contractually or set annually and actual payout levels are determined after the year end,
based on performance against targets subject to overriding discretion of the Compensation Committee.
The
maximum annual bonus payable for any financial year is 100% of target bonus, although the Compensation Committee reserves the right to
vary this amount in exceptional circumstances and based on assessment of Company and individual performance and goals achievement.
Where
performance conditions are attached to a bonus payment, targets are either fixed contractually
or selected by the Compensation Committee and set annually and can include key financial,
operational and/or individual objectives.
All
assessments of performance against target is made by the Compensation Committee in its sole discretion.
No
provisions for recovery or withholding of sums as the performance measures are considered adequate.
Equity
Incentive Plan
(2014 Equity Incentive Plan 2023 Equity Incentive Plan )
To
motivate and reward long-term performance in alignment with the shareholder interests and value- creation
Awards
may be made periodically to Executive Officers in the form of options or in shares including
stock appreciation rights, phantom stock awards or restricted stock units.
Awards
typically vest over two or four years and may be subject to incremental vesting.
There
is no specific maximum set for annual equity awards.
When
making awards, the Compensation Committee will take into account internal grant guidelines, which have been set in reference to local
market norms.
Where
performance conditions are attached to an award, these typically include key financial, operational
and/or individual objectives subject to overall Compensation Committee discretion.
No
provisions for recovery or withholding of sums as the performance measures are considered adequate.
CSOP
(UK resident employees and directors only)
Executives
are eligible to participate in the all- employee CSOP Plan under the same conditions as all other employees.
Grant
value of 30,000 or local market rulesas amended from time to time.
None.
No
provisions for recovery or withholding of sums as this is not performance-related.
52
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
Policy Table Non-Executive Directors
Akaris non-executive compensation policy
is administered by its Board of Directors (the Board) with the assistance of the Compensation Committee. The Compensation
committee periodically reviews the non-executive director compensation policy and makes recommendations to the Board.
Non-Executive Directors typically receive an
annual retainer paid in cash for their service (depending on their additional membership and chairman responsibilities) and an annual
grant of stock options but do not participate in the bonus plan to which Executive Officers are eligible, nor do they typically receive
any other performance related payment. There are no elements of the non-executive director compensation policy which are subject to performance
conditions given the necessity to maintain directors independence and board effectiveness in corporate governance, and accordingly
there are no provisions for recovery or withholding of sums.
The table below sets out some of the features
of Akaris current non-employee director compensation policy:
Element
Purpose
and
Link to Strategy
Operation
Maximum
Opportunity
Performance
Metrics
Annual
Cash Retainer Fee
Support
the recruitment and retention of Non- Executive Directors
Each
Non-Executive Director serving on the Board receives an annual cash retainer, with additional
amounts payable for acting as a chairman or a member of various committees.
In
addition, the Chairman receive an additional cash retainer.
Annual
cash retainers are typically payable on a quarterly basis with the exception of the Executive Chairman who is paid monthly.
A
Non-Executive Director may elect to receive annual cash payments in the form of fully- vested ordinary shares.
There
is no prescribed maximum increase nor any requirement to increase salary at any time.
None.
Share
Options
Strengthens
the alignment to shareholders interests through share ownership
Directors
typically receive an annual grant of options in the form of market value options under the
Companys Equity Incentive Plan then in effect.
These
awards typically vest in full on the date of the next AGM following the date of grant, subject to the Non-Executive Directors
continued service on the Board, have a term of 10years from date of grant, and vesting accelerates in the case of a change
of control.
Normal
initial grant and annual grant of share options will be equal to 5,000,000 (or equivalent value of ADS) but the Committee reserves the
discretion to review and amend this amount.
None.
53
AKARI THERAPEUTICS, PLC
DIRECTORS REMUNERATION REPORT (continued)
FOR THE YEAR ENDED 31 DECEMBER 2023
The foregoing is qualified in its entirety by
Akaris current non-executive director compensation policy, as may be amended from time to time
Approach to Recruitment Compensation
Akaris policy is to pay a fair remuneration
package for the role being undertaken and the experience of the individual to be appointed. Akari expects remuneration packages for Executive
Directors to include base salary, targeted level of annual cash incentive, initial and ongoing equity-based awards, standard benefits
and special provisions tailored to the recruiting situation, such as: sign-on bonus, reasonable relocation support and make-whole awards
for remuneration forfeited from a prior employer (whether on account of cash bonuses, share awards, pension benefits or other forfeited
items). The Compensation Committee retains the discretion to provide additional cash, share based payment, benefits and other remuneration
where necessary or useful to recruit new Executive Directors or to secure the ongoing service of existing Executive Directors. The remuneration
package for any new non-Executive Director will be set in accordance with the terms of Akaris nonemployee director compensation
policy then in effect. Akari expects remuneration packages for non-Executive Directors to include an annual retainer paid in cash for
their service (depending on their additional membership and chairman responsibilities) and an annual grant of stock options. Non-Executive
Directors do not participate in the bonus plan to which Executive Officers are eligible, nor do they typically receive any other performance
related payment.
Directors Service Contracts
Akaris board of directors is divided into
three classes for purposes of election (ClassA Directors, who serve a one year term before being subject to re-election at Akaris
annual general meeting; ClassB Directors, who serve a two year term before being subject to re-election at the annual general meeting;
and ClassC Directors who serve a three year term before being subject to re-election at the annual general meeting, provided also
that in any two year period, a majority of the board must stand for re-election).
It is the Companys policy that executive
Directors should have contracts with an indefinite term. Directors notice periods are set by the compensation committee, having
regard to the need to attract and retain talent, ensure an orderly succession and enable the company to manage its personnel while avoiding
excessive costs. Service contracts are available for inspection at Akaris registered office or 75/76 Wimpole Street London W1G
9RT.
Policy on Payments for Loss of Office
Akaris approach to payments to Executive
Directors in the event of termination is to take account of the individual circumstances including the reason for termination, individual
performance, contractual obligations and the terms of any option award.
Generally, Akari employment arrangements for
Executive Directors include a notice provision and continuing payment obligations as per the individual Executive Director service contracts
following termination by Akari of an Executive Director without cause or termination by the Executive Director for good reason or change
of control. Payment obligations, if any, include base salary, benefits, and all or some portion of target annual cash remuneration. Akari
may offer payment in lieu of notice if it is considered to be in the best interests of Akari.
Treatment of unvested outstanding equity awards
will be determined according to the specific nature of termination, individual contracts, and plan rules.
The Compensation Committee reserves the right
to make payments it considers reasonable under a compromise or settlement agreement, including payment or reimbursement of reasonable
legal and professional fees, and any payment or compensation (in whatever form) in respect of statutory rights under employment law in
the US, UK or other jurisdictions. Payment or reimbursement (in whatever forms) of reasonable outplacement fees may also be provided.
Other
Relevant I
nformation Considered
As appropriate, the Compensation Committee considers
the pay and conditions of the broader employee workforce, as well as the Consumer Price Index and Retail Price Index, when making compensation
related decisions for the directors. The Compensation Committee does not consult employees, other than Executive Directors, when drafting
the Policy.
The Compensation Committee also considers shareholder
feedback, so far as it relates to compensation, when reviewing the appropriateness of the Policy. In addition, the Compensation Committee
considers potential conflicts of interest and directors do not have sole discretion over their own remuneration.
This report was approved by the Board on 3 June2024
and signed on its behalf.
54
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1.1 14475
AKARI THERAPEUTICS, PLC
Proxy for the Annual General Meeting of Shareholders on June 27, 2024
2:00 PM BST (9:00 AM EST)
(Continued and to be signed on the reverse side)
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Alternatively you can provide us with your email address in the below section entitled “ELECTRONIC SHAREHOLDER COMMUNICATIONS” to receive
future materials electronically when available.
1. To receive the report of the Board of Directors and the accounts for the year ended December 31, 2023, together with the report of the statutory auditor and the strategic report.
2. To approve the Board of Directors’ Remuneration Report (excluding the Board of Directors’ Remuneration Policy), as set out in the Company’s annual report and accounts for the financial year ended December 31, 2023.
3. To re-elect Donald Williams as a director of Akari, as a Class A Director as stated in Article 18.2.1 of the Company’s articles of association (the “Articles”).
4. To re-elect Michael Grissinger as a director of Akari, as a Class A Director as stated in Article 18.2.1 of the Articles.
5 To re-elect Mohamed Wa’El Ahmed Hashad as a director of Akari, as a Class A Director as stated in Article 18.2.1 of the Articles.
6. To re-elect Samir Patel as a director of Akari, as a Class A Director as stated in Article 18.2.1 of the Articles.
7. To re-elect Raymond Prudo-Chlebosz, M.D. as a director of Akari, as a
Class C Director as stated in Article 18.2.3 of the Articles.
8. To ratify the appointment of BDO USA, P.C. as independent registered public account-ing firm of Akari for the year ending December 31, 2024.
9. To ratify the appointment of Haysmacintyre LLP as statutory auditors of Akari to hold office until the conclusion of the next annual general meeting at which accounts are laid before Akari shareholders.
10. To authorize the audit committee of the Board of Directors of Akari to fix the statutory auditors’ remuneration.
11. To approve, on a non-binding, advisory basis, the compensation of our named exec- utive officers ("NEOs") as disclosed in the Proxy Statement.
12. To indicate, on a non-binding, advisory basis, the preferred frequency of future shareholder advisory votes on the compensation of Akari’s NEOs.
FOR AGAINST ABSTAIN
THE AKARI BOARD OF DIRECTORS RECOMMENDS THAT AKARI SHAREHOLDERS VOTE “FOR” RESOLUTIONS 1-11 AND "ONE YEAR" FOR RESOLUTION 12.
PLEASE SIGN, DATE AND RETURN PROMPTLY IN THE ENCLOSED ENVELOPE. PLEASE MARK YOUR VOTE IN BLUE OR BLACK INK AS SHOWN HERE x
Please detach along perforated line and mail in the envelope provided.
062724
ANNUAL GENERAL MEETING OF SHAREHOLDERS OF
AKARI THERAPEUTICS, PLC
June 27, 2024
2:00 PM BST (9:00 AM EST)
Please vote, sign, date and
mail your proxy card in the
envelope provided so that
your vote is received on or
before June 17, 2024 at
1:00 p.m. EST
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Ordinary Resolutions FOR AGAINST ABSTAIN
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1 YEAR 2 YEARS 3 YEARS ABSTAIN
This proxy is being solicited on behalf of the Board of Directors
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