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Proposal 1: Elect Director
|
| | The nominees for director who receive the most votes (also known as a “plurality” of the votes cast) will be elected. You may vote either FOR the nominees or WITHHOLD your vote from the nominees. Votes that are withheld will not be included in the vote tally for the election of the director. Brokerage firms do not have authority to vote customers’ unvoted shares held by the firms in street name for the election of the directors. As a result, any shares not voted by a customer will be treated as a broker non-vote. Such broker non-votes will have no effect on the results of this vote. | |
| |
Proposal 2: Ratify Appointment of Independent Registered Public Accounting Firm
|
| | The affirmative vote of a majority of the shares cast affirmatively or negatively for this proposal is required to ratify the appointment of our independent registered public accounting firm. Abstentions will have no effect on the results of this vote. Brokerage firms have authority to vote customers’ unvoted shares held by the firms in street name on this proposal. If a broker does not exercise this authority, such broker non-votes will have no effect on the results of this vote. We are not required to obtain the approval of our stockholders to appoint our independent registered public accounting firm. However, if our stockholders do not ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for 2025, our audit committee of our board of directors will reconsider its selection. | |
| | | |
Shares Beneficially Owned
|
| |||||||||
|
Name and Address
(1)
|
| |
Number
|
| |
Percent
|
| ||||||
| Greater than 5% Stockholders: | | | | | | | | | | | | | |
|
Entities affiliated with BlackRock, Inc.
(2)
|
| | | | 1,963,494 | | | | | | 5.77 % | | |
|
Entities affiliated with Hillhouse Investment Management, Ltd.
(3)
|
| | | | 4,484,672 | | | | | | 13.17 % | | |
|
Entities affiliated with Octagon Capital Advisors LP
(4)
|
| | | | 1,976,387 | | | | | | 5.81 % | | |
|
Entities affiliated with OrbiMed
(5)
|
| | | | 3,027,328 | | | | | | 8.89 % | | |
|
Entities affiliated with Suvretta Capital Management, LLC
(6)
|
| | | | 2,246,000 | | | | | | 6.60 % | | |
|
FMR LLC
(7)
|
| | | | 2,101,037 | | | | | | 6.17 % | | |
|
LAV Fund VI, L.P.
(8)
|
| | | | 1,966,123 | | | | | | 5.78 % | | |
|
Novo Holdings A/S
(9)
|
| | | | 1,750,000 | | | | | | 5.14 % | | |
| Named Executive Officers and Directors: | | | | | | | | | | | | | |
|
Zhengbin (Bing) Yao, Ph.D.
(10)
|
| | | | 1,092,286 | | | | | | 3.16 % | | |
|
Winston Kung, MBA
(11)
|
| | | | 69,858 | | | | | | * | | |
|
Stuart Lutzker, M.D., Ph.D.
(12)
|
| | | | 308,219 | | | | | | * | | |
|
Carl L. Gordon, Ph.D., CFA
(13)
|
| | | | 3,027,328 | | | | | | 8.89 % | | |
|
James Healy, M.D., Ph.D.
(14)
|
| | | | 1,696,752 | | | | | | 4.98 % | | |
|
John Hohneker, M.D.
(15)
|
| | | | 9,850 | | | | | | * | | |
|
Chris W. Nolet
(16)
|
| | | | 23,363 | | | | | | * | | |
|
Kristine Peterson
(17)
|
| | | | 9,529 | | | | | | * | | |
|
Merdad Parsey, M.D., Ph.D.
(18)
|
| | | | — | | | | | | * | | |
|
All current executive officers and directors as a group (11 persons)
(19)
|
| | | | 6,482,689 | | | | | | 18.58 % | | |
|
Name
|
| |
Age
|
| |
Position
|
|
| Zhengbin (Bing) Yao, Ph.D. | | | 59 | | |
Chief Executive Officer and Chairman of Board
|
|
| Stuart Lutzker, M.D., Ph.D. | | | 64 | | | President, Research and Development and Director | |
| Carl L. Gordon, Ph.D., CFA | | | 60 | | | Director | |
| James Healy, M.D., Ph.D. (1)(3) | | | 60 | | | Director | |
| John Hohneker, M.D. (2)(3) | | | 65 | | | Director | |
| Chris W. Nolet (1)(3) | | | 68 | | | Director | |
| Merdad Parsey, M.D., Ph.D. (2) | | | 62 | | | Director | |
| Kristine Peterson (1)(2) | | | 65 | | | Lead Independent Director | |
|
Name
|
| |
Age
|
| |
Position
|
|
| Winston Kung, MBA | | | 49 | | | Chief Financial Officer and Treasurer | |
| Robin LaChapelle | | | 52 | | | Chief Operating Officer | |
| James Kastenmayer, J.D., Ph.D. | | | 53 | | | General Counsel and Secretary | |
|
Name and Principal Position
|
| |
Year
|
| |
Salary
($) (1) |
| |
Option
Awards ($) (2) |
| |
Non-Equity
Incentive Plan Compensation ($) (3) |
| |
All Other
Compensation ($) (4) |
| |
Total
($) |
| ||||||||||||||||||
|
Zhengbin (Bing) Yao, Ph.D..............
Chief Executive Officer and President |
| | | | 2024 | | | | | | 558,183 | | | | | | 1,596,043 | | | | | | 238,623 | | | | | | 13,800 | | | | | | 2,406,649 | | |
| | | | 2023 | | | | | | 536,475 | | | | | | 394,693 | | | | | | 241,414 | | | | | | 13,200 | | | | | | 1,185,782 | | | ||
|
Stuart Lutzker, M.D., Ph.D..............
President, Research and Development |
| | | | 2024 | | | | | | 495,941 | | | | | | 297,457 | | | | | | 179,035 | | | | | | 13,534 | | | | | | 985,967 | | |
| | | | 2023 | | | | | | 476,867 | | | | | | 119,326 | | | | | | 219,359 | | | | | | 13,200 | | | | | | 828,752 | | | ||
|
Winston Kung, MBA
(5)
....................
Chief Financial Officer and Treasurer |
| | | | 2024 | | | | | | 469,602 | | | | | | 1,190,331 | | | | | | 158,840 | | | | | | 13,800 | | | | | | 1,832,573 | | |
| | | | 2023 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | ||
| | | | | | | | | |
Option Awards
(1)(2)
|
| |||||||||||||||||||||
|
Name
|
| |
Option
Grant Date |
| |
Number of
Securities Underlying Unexercised Options (#) Exercisable |
| |
Number of
Securities Underlying Unexercised Options (#) Unexercisable |
| |
Option
Exercise Price ($) |
| |
Option
Expiration Date |
| |||||||||||||||
|
Zhengbin (Bing) Yao, Ph.D..............................
|
| | | | 9/8/2021 | | | | | | 85,474 | | | | | | 19,719 | | | | | $ | 2.28 | | | | | | 9/7/2031 | | |
| | | | 2/1/2022 | | | | | | 100,128 | | | | | | 41,225 | | | | | $ | 2.28 | | | | | | 1/31/2032 | | | ||
| | | | 2/1/2022 | | | | | | 73,583 | | | | | | 30,295 | | | | | $ | 2.28 | | | | | | 1/31/2032 | | | ||
| | | | 2/1/2023 | | | | | | 64,789 | | | | | | 76,564 | | | | | $ | 3.65 | | | | | | 1/31/2033 | | | ||
| | | | 1/1/2024 | | | | | | — | | | | | | 264,574 | | | | | $ | 7.76 | | | | | | 12/31/2033 | | | ||
|
Stuart Lutzker, M.D., Ph.D..............................
|
| | | | 9/8/2021 | | | | | | 53,425 | | | | | | 12,321 | | | | | $ | 2.28 | | | | | | 9/7/2031 | | |
| | | | 2/1/2022 | | | | | | 17,703 | | | | | | 7,280 | | | | | $ | 2.28 | | | | | | 1/31/2032 | | | ||
| | | | 2/1/2022 | | | | | | 30,274 | | | | | | 12,460 | | | | | $ | 2.28 | | | | | | 1/31/2032 | | | ||
| | | | 2/1/2023 | | | | | | 19,586 | | | | | | 23,148 | | | | | $ | 3.65 | | | | | | 1/31/2033 | | | ||
| | | | 1/1/2024 | | | | | | — | | | | | | 49,309 | | | | | $ | 7.76 | | | | | | 12/31/2033 | | | ||
|
Winston Kung, MBA.......................................
|
| | | | 1/4/2024 | | | | | | — | | | | | | 197,238 | | | | | $ | 7.76 | | | | | | 1/3/2034 | | |
|
Name
|
| |
Fees Earned or
Paid in Cash ($) |
| |
Option
Awards ($) (1) |
| |
Total ($)
|
| |||||||||
|
Carl L. Gordon, Ph.D., CFA
|
| | | | — | | | | | | — | | | | | | — | | |
|
James Healy, M.D., Ph.D.
|
| | | | — | | | | | | — | | | | | | — | | |
|
John Hohneker, M.D.
|
| | | | 28,063 | | | | | | 476,943 | | | | | | 505,006 | | |
|
Chris W. Nolet
|
| | | | 65,000 | | | | | | 278,525 | | | | | | 343,525 | | |
|
Kristine Peterson
|
| | | | 31,030 | | | | | | 364,790 | | | | | | 395,820 | | |
|
Bahija Jallal, Ph.D.
(2)
|
| | | | 15,000 | | | | | | 278,525 | | | | | | 293,525 | | |
|
Merdad Parsey, M.D., Ph.D.
(3)
|
| | | | — | | | | | | — | | | | | | — | | |
|
Position
|
| |
Retainer
|
| |||
|
Board Member
|
| | | $ | 45,000 | | |
|
Lead Independent Director
|
| | | $ | 30,000 | | |
|
Audit Committee Chair
|
| | | $ | 20,000 | | |
|
Audit Committee Member
|
| | | $ | 10,000 | | |
|
Compensation Committee Chair
|
| | | $ | 15,000 | | |
|
Compensation Committee Member
|
| | | $ | 7,500 | | |
|
Nominating and Corporate Governance Committee Chair
|
| | | $ | 10,000 | | |
|
Nominating and Corporate Governance Committee Member
|
| | | $ | 5,000 | | |
| | | |
(a)
|
| |
(b)
|
| |
(c)
|
| |||||||||
|
Plan category
|
| |
Number of
securities to be issued upon exercise of outstanding options, warrants and rights (1) |
| |
Weighted-
average exercise price of outstanding options, warrants and rights |
| |
Number of
securities remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) (2) |
| |||||||||
|
Equity compensation plans approved by security
holders (1) |
| | | | 2,531,181 | | | | | $ | 3.0354 | | | | | | 3,767,039 | | |
|
Equity compensation plans not approved by security holders
|
| | | | — | | | | | | — | | | | | | — | | |
|
Total
|
| | | | 2,531,181 | | | | | $ | 3.0354 | | | | | | 3,767,039 | | |
|
Name
|
| |
Shares of
Series B Convertible Preferred Stock Purchased |
| |
Aggregate
Purchase Price |
| ||||||
|
Entities affiliated with Hillhouse Investment Management, Ltd.
(1)
|
| | | | 4,761,903 | | | | | $ | 4,999,998.15 | | |
|
LAV Fund VI, L.P.
(2)
|
| | | | 1,904,761 | | | | | $ | 1,999,999.05 | | |
|
Entities affiliated with Octagon Capital Advisors LP
(3)
|
| | | | 9,523,808 | | | | | $ | 9,999,998.40 | | |
|
Entities affiliated with OrbiMed
(4)
|
| | | | 14,285,714 | | | | | $ | 14,999,999.70 | | |
|
Sofinnova Venture Partners XI, L.P.
(5)
|
| | | | 19,047,619 | | | | | $ | 19,999,999.95 | | |
|
Entities affiliated with Sirona Capital Partners Ltd.
(6)
|
| | | | 9,523,808 | | | | | $ | 9,999,998.40 | | |
| | | |
Shares
|
| |
Aggregate
Purchase Price |
| ||||||
|
LAV Fund VI, L.P.
|
| | | | 100,000 | | | | | $ | 1,800,000 | | |
|
Entities affiliated with Octagon Capital Advisors LP
|
| | | | 200,000 | | | | | | 3,600,000 | | |
|
Entities affiliated with OrbiMed
|
| | | | 444,444 | | | | | | 7,999,992 | | |
|
Sofinnova Venture Partners XI, L.P.
|
| | | | 444,444 | | | | | | 7,999,992 | | |
|
Entities affiliated with Hillhouse Investment Management, Ltd
|
| | | | 555,555 | | | | | $ | 9,999,990 | | |
| | | |
2024
|
| |
2023
|
| ||||||
|
Audit Fees
(1)
|
| | | $ | 1,180,925 | | | | | $ | 1,120,000 | | |
|
Audit-Related Fees
(2)
|
| | | | — | | | | | | — | | |
|
Tax Fees
(3)
|
| | | | — | | | | | | — | | |
|
All Other Fees
(4)
|
| | | | — | | | | | | — | | |
| Total | | | | $ | 1,180,925 | | | | | $ | 1,120,000 | | |
No information found
* THE VALUE IS THE MARKET VALUE AS OF THE LAST DAY OF THE QUARTER FOR WHICH THE 13F WAS FILED.
| FUND | NUMBER OF SHARES | VALUE ($) | PUT OR CALL |
|---|
| DIRECTORS | AGE | BIO | OTHER DIRECTOR MEMBERSHIPS |
|---|
No information found
No Customers Found
No Suppliers Found
Price
Yield
| Owner | Position | Direct Shares | Indirect Shares |
|---|