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| | | | | 43 | | | |
| | | | | 44 | | | |
| | | | | 51 | | | |
| | | | | 52 | | | |
|
Nominee
|
| |
Director
Since |
| |
Principal Occupation or Experience
|
| |
Committees
|
|
| Gregory J. Divis | | |
2019
|
| | Chief Executive Office of the Company. | | | | |
| Dr. Eric J. Ende | | |
2018
|
| | President at Ende BioMedical Consulting Group; Director at Matinas BioPharma, Inc. | | |
(2)(3)(4*)
|
|
| Geoffrey M. Glass | | |
2018
|
| | President at Clear Sciences, LLC; former Chief Executive Officer and Director at Sancilio Pharmaceuticals | | |
(1)(2)(3)(4)
|
|
|
Dr. Mark A. McCamish
|
| |
2019
|
| | President and Chief Executive Officer of Forty Seven, Inc. | | |
(2)
|
|
| Linda S. Palczuk | | |
2018
|
| | Chief Operating Officer and Director of Envara Health, Inc. | | |
(3*)(4)
|
|
| Peter Thornton | | |
2017
|
| | Chief Financial Officer at Technopath Clinical Diagnostics | | |
(2*)(3)(4)
|
|
|
Name
|
| |
Age
|
| |
Position
|
|
| Gregory J. Divis | | |
54
|
| | Chief Executive Officer and Director | |
| Thomas S. McHugh | | |
55
|
| | Chief Financial Officer | |
| Jordan S. Dubow, M.D. | | |
42
|
| | Chief Medical Officer | |
| Geoffrey M. Glass | | |
46
|
| | Chairman of the Board of Directors | |
| Eric J. Ende, M.D. | | |
51
|
| | Director | |
| Mark A. McCamish, M.D., Ph.D. | | |
68
|
| | Director | |
| Linda S. Palczuk | | |
58
|
| | Director | |
| Peter Thornton | | |
55
|
| | Director | |
|
Name
|
| |
Fees Earned or
Paid in Cash ($) (1) |
| |
Option
Awards ($) (2)(3) |
| |
Stock
Awards ($) (2)(4) |
| |
Total
Compensation ($) |
| ||||||||||||
|
Geoffrey M. Glass
(5)
|
| | | $ | 305,024 (6) | | | | | | 67,800 | | | | | | — | | | | | $ | 372,824 | | |
|
Dr. Eric J. Ende
(7)
|
| | | $ | 64,719 | | | | | | 74,500 | | | | | | 42,129 | | | | | $ | 181,348 | | |
|
Dr. Mark A. McCamish
(8)
|
| | | $ | — | | | | | | — | | | | | | — | | | | | $ | — | | |
|
Linda S. Palczuk
(9)
|
| | | $ | 67,453 | | | | | | 67,800 | | | | | | — | | | | | $ | 135,253 | | |
|
Peter Thornton
(10)
|
| | | $ | 73,338 | | | | | | 67,800 | | | | | | — | | | | | $ | 141,138 | | |
|
Kevin Kotler
(11)
|
| | | $ | 54,405 | | | | | | 67,800 | | | | | | 42,129 | | | | | $ | 164,334 | | |
|
Craig Stapleton
|
| | | $ | 17,113 | | | | | | — | | | | | | — | | | | | $ | 17,113 | | |
|
Name and Address of Beneficial Owners
(1)
|
| |
Amount of
Beneficial Ownership (2) |
| |
Percentage of
Class (2) |
| ||||||
| >5% Shareholders: | | | | | | | | | | | | | |
|
RTW Investments, L.P.
(3)
415 West 15th Street, Floor 9 New York, NY 10011 |
| | | | 4,616,570 | | | | | | 9.95 % | | |
|
Vivo Capital LLC
(4)
192 Lytton Avenue Palo Alto, CA 94301 |
| | | | 3,526,093 | | | | | | 7.60 % | | |
|
Avoro Capital Advisors LLC
(5)
110 Greene Street, Suite 800, New York, NY 10012 |
| | | | 3,895,655 | | | | | | 8.39 % | | |
| Directors, Director Nominees and Named Executive Officers: | | | | | | | | | | | | | |
|
Gregory J. Divis
(6)
|
| | | | 186,100 | | | | | | * | | |
|
Thomas S. McHugh
|
| | | | — | | | | | | * | | |
|
Dr. Jordan S. Dubow
(7)
|
| | | | 85,000 | | | | | | * | | |
|
Phillandas T. Thompson
|
| | | | 113,671 | | | | | | * | | |
|
Sandra Hatten
|
| | | | 59,165 | | | | | | * | | |
|
Michael F. Kanan
|
| | | | 50,538 | | | | | | * | | |
|
Geoffrey M. Glass
|
| | | | 47,900 | | | | | | * | | |
|
Dr. Eric J. Ende
|
| | | | 47,900 | | | | | | * | | |
|
Dr. Mark A. McCamish
|
| | | | — | | | | | | * | | |
|
Linda S. Palczuk
|
| | | | 35,400 | | | | | | * | | |
|
Peter Thornton
|
| | | | 33,055 | | | | | | * | | |
|
All directors and executive officers as a group (11 persons)
(8)
|
| | | | 658,729 | | | | | | 1.41 % | | |
|
Name
|
| |
Position
|
|
| Gregory J. Divis | | | Chief Executive Officer | |
| Thomas S. McHugh | | | Senior Vice President and Chief Financial Officer | |
| Michael F. Kanan | | | Former Chief Financial Officer | |
| Phillandas T. Thompson | | | Senior Vice President, General Counsel and Corporate Secretary | |
| Jordan S. Dubow, M.D. | | | Chief Medical Officer | |
| |
2019 Peer Group
|
| |||
| |
Aeglea BioTherapeutics, Inc.
|
| |
Iterum Therapeutics plc
|
|
| |
Aldeyra Therapeutics, Inc.
|
| |
Marinus Pharmaceuticals, Inc.
|
|
| |
Allena Pharmaceuticals, Inc.
|
| |
Millendo Theraeputics, Inc.
|
|
| |
Aridis Pharmaceuticals, Inc.
|
| |
Otonomy, Inc.
|
|
| |
Catalyst Biosciences, Inc.
|
| |
Savara Inc.
|
|
| |
Chiasma, Inc.
|
| |
Sesen Bio
|
|
| |
Chimerix
|
| |
Spero Therapeutics, Inc.
|
|
| |
CymaBay Therapeutics, Inc.
|
| |
Syndax Pharmaceuticals, Inc.
|
|
| |
Entasis Therapeutics Holdings Inc.
|
| |
Zynerba Pharmaceuticals, Inc.
|
|
| |
GlycoMimetics, Inc.
|
| | | |
|
Name
|
| |
2018 Base
Salary ($) |
| |
2019 Base
Salary ($) |
| |
Increase
(%) |
| |||||||||
|
Gregory J. Divis
|
| | | | 425,000 | | | | | | 433,500 (1) | | | | | | 2 % | | |
|
Thomas S. McHugh
(2)
|
| | | | — | | | | | | 385,000 | | | | | | — | | |
|
Sandra Hatten
|
| | | | 314,445 | | | | | | 323,092 | | | | | | 2.7 % | | |
|
Michael F. Kanan
|
| | | | 386,100 | | | | | | 396,718 | | | | | | 2.7 % | | |
|
Phillandas Thompson
|
| | | | 365,968 | | | | | | 383,400 | | | | | | 4.5 % | | |
|
Jordan S. Dubow, M.D.
(3)
|
| | | | — | | | | | | 435,000 | | | | | | — | | |
|
Name
|
| |
2019 Target Bonus
(as a % of Base Salary) |
| |
2019
Target Bonus ($) |
| ||||||
|
Gregory J. Divis
(1)
|
| | | | 50 % | | | | | | 265,312 | | |
|
Thomas S. McHugh
(2)
|
| | | | — | | | | | | — | | |
|
Michael F. Kanan
|
| | | | 40 % | | | | | | 158,687 | | |
|
Phillandas Thompson
|
| | | | 40 % | | | | | | 153,360 | | |
|
Jordan S. Dubow, M.D.
|
| | | | 45 % | | | | | | 195,750 | | |
|
Sandra Hatten
|
| | | | 40 % | | | | | | 129,237 | | |
|
Name
|
| |
Stock
Options |
| |
Restricted
Shares |
| ||||||
|
Gregory J. Divis
|
| | | | 100,000 | | | | | | 18,000 | | |
|
Michael F. Kanan
|
| | | | 80,000 | | | | | | 18,000 | | |
|
Philandas Thompson
|
| | | | 100,000 | | | | | | 18,000 | | |
|
Name and
Principal Position |
| |
Year
|
| |
Base
Salary ($) (1) |
| |
Stock
Awards ($) (2) |
| |
Option
Awards ($) (3) |
| |
Non-Equity
Incentive Plan Compensation ($) (4) |
| |
All
Other Compensation ($) (5) |
| |
Total
Compensation ($) |
| |||||||||||||||||||||
|
Gregory J. Divis
Chief Executive Officer |
| | | | 2019 | | | | | | 472,292 | | | | | | 33,300 | | | | | | 485,010 | | | | | | 422,344 | | | | | | 23,316 | | | | | | 1,436,262 | | |
| | | | 2018 | | | | | | 417,178 | | | | | | — | | | | | | 198,500 | | | | | | 46,750 | | | | | | 23,000 | | | | | | 685,428 | | | ||
| | | | 2017 | | | | | | 375,000 | | | | | | 201,375 | | | | | | 505,000 | | | | | | 158,438 | | | | | | 22,800 | | | | | | 1,262,613 | | | ||
|
Michael F. Kanan
Former Senior Vice President and Chief Financial Officer |
| | | | 2019 | | | | | | 396,718 | | | | | | 33,300 | | | | | | 82,600 | | | | | | 161,861 | | | | | | 453,232 (6) | | | | | | 1,127,711 | | |
| | | | 2018 | | | | | | 386,100 | | | | | | — | | | | | | — | | | | | | 67,954 | | | | | | 23,000 | | | | | | 477,054 | | | ||
| | | | 2017 | | | | | | 357,500 | | | | | | 161,100 | | | | | | 404,000 | | | | | | 120,835 | | | | | | 22,800 | | | | | | 1,066,235 | | | ||
|
Thomas S. McHugh
Chief Financial Officer |
| | | | 2019 | | | | | | 33,688 | | | | | | — | | | | | | 469,600 | | | | | | — | | | | | | — | | | | | | 503,288 | | |
|
Jordan S. Dubow
Chief Medical Officer |
| | | | 2019 | | | | | | 293,296 | | | | | | — | | | | | | 273,258 | | | | | | 166,388 | | | | | | 10,282 | | | | | | 743,224 | | |
|
Phillandas T. Thompson
Senior Vice President and General Counsel |
| | | | 2019 | | | | | | 383,400 | | | | | | 33,300 | | | | | | 103,250 | | | | | | 156,427 | | | | | | 21,780 | | | | | | 698,157 | | |
| | | | 2018 | | | | | | 365,968 | | | | | | — | | | | | | — | | | | | | 64,410 | | | | | | 20,000 | | | | | | 450,378 | | | ||
| | | | 2017 | | | | | | 326,757 | | | | | | 161,100 | | | | | | 404,000 | | | | | | 110,444 | | | | | | 19,800 | | | | | | 1,022,101 | | | ||
|
Sandra Hatten
Former Senior Vice President of Quality and Regulatory Affairs |
| | | | 2019 | | | | | | 323,092 | | | | | | 33,300 | | | | | | 82,600 | | | | | | 131,822 | | | | | | 346,306 (7) | | | | | | 917,120 | | |
| | | | 2018 | | | | | | 314,445 | | | | | | — | | | | | | — | | | | | | 55,342 | | | | | | 11,000 | | | | | | 380,787 | | | ||
| | | | 2017 | | | | | | 305,286 | | | | | | 111,875 | | | | | | 303,000 | | | | | | 103,187 | | | | | | 10,800 | | | | | | 834,148 | | | ||
| | | | | | | | | |
Estimated Possible Payouts Under
Non-Equity Incentive Plan Awards (1) |
| |
All Other
Stock Awards: Number of Shares of Stock or Units (#) |
| |
All Other
Option Awards: Number of Securities Underlying Options (#) |
| |
Exercise
or Base Price of Option Awards |
| |
Grant Date
Fair Value of Award ($) (2) |
| |||||||||||||||||||||||||||
|
Name
|
| |
Grant
Date |
| |
Threshold
($) |
| |
Target
($) |
| |
Maximum
($) |
| ||||||||||||||||||||||||||||||||||||
|
Gregory J. Divis
|
| | | | | | | | | | — | | | | | $ | 300,000 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 100,000 | | | | | $ | 1.85 | | | | | $ | 103,250 | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
| | | | | | 5/30/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 400,000 | | | | | $ | 1.71 | | | | | $ | 381,760 | | |
|
Michael F. Kanan
|
| | | | | | | | | | — | | | | | $ | 158,687 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 80,000 | | | | | $ | 1.85 | | | | | $ | 82,600 | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
|
Thomas S. McHugh
|
| | | | | | | | | | — | | | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 10/22/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 250,000 | | | | | $ | 3.45 | | | | | $ | 469,600 | | |
|
Jordan S. Dubow, M.D.
|
| | | | | | | | | | — | | | | | $ | 195,750 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 4/11/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 340,000 | | | | | $ | 1.44 | | | | | $ | 273,258 | | |
|
Phillandas Thompson
|
| | | | | | | | | | — | | | | | $ | 153,360 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 100,000 | | | | | $ | 1.85 | | | | | $ | 103,250 | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
|
Sandra Hatten
|
| | | | | | | | | | — | | | | | $ | 129,237 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 80,000 | | | | | $ | 1.85 | | | | | $ | 82,600 | | |
| | | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
| | | | | | | | | |
Option Awards
|
| |
Stock Awards
|
| ||||||||||||||||||||||||||||||
|
Name
|
| |
Grant Date
|
| |
Number of
Securities Underlying Unexercised Options (#) Exercisable (1) |
| |
Number of
Securities Underlying Unexercised Options (#) Unexercisable (1) |
| |
Option
Exercise Price ($) |
| |
Option
Expiration Date |
| |
Number
of Shares or Units of Stock That Have Not Vested (#) (2) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested ($) (2) |
| |||||||||||||||||||||
|
Gregory J. Divis
|
| | | | 12/14/2016 | | | | | | 112,500 | | | | | | 37,500 (3) | | | | | $ | 10.40 | | | | | | 12/14/2026 | | | | | | — | | | | | | — | | |
| | | | | | 12/12/2017 | | | | | | 50,000 | | | | | | 50,000 (4) | | | | | $ | 8.95 | | | | | | 12/12/2027 | | | | | | — | | | | | | — | | |
| | | | | | 3/22/2018 | | | | | | — | | | | | | 50,000 (5) | | | | | $ | 7.06 | | | | | | 3/22/2028 | | | | | | — | | | | | | — | | |
| | | | | | 3/7/2019 | | | | | | — | | | | | | 100,000 (6 ) | | | | | $ | 1.85 | | | | | | 3/7/2029 | | | | | | — | | | | | | — | | |
| | | | | | 3/7/2019 | | | | | | — | | | | | | — | | | | | $ | — | | | | | | — | | | | | | 18,000 (7) | | | | | $ | 135,900 | | |
| | | | | | 5/30/2019 | | | | | | — | | | | | | 400,000 (8) | | | | | $ | 1.71 | | | | | | 5/30/2029 | | | | | | — | | | | | | — | | |
|
Michael F. Kanan
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
|
Thomas S. McHugh
|
| | | | 10/22/2019 | | | | | | — | | | | | | 250,000 (9) | | | | | $ | 3.45 | | | | | | 10/22/2029 | | | | | | — | | | | | | — | | |
|
Jordan S. Dubow, M.D.
|
| | | | 4/11/2019 | | | | | | — | | | | | | 340,000 (10) | | | | | $ | 1.44 | | | | | | 4/11/2029 | | | | | | — | | | | | | — | | |
|
Phillandas T. Thompson
|
| | | | 12/12/2017 | | | | | | 40,000 | | | | | | 40,000 (11) | | | | | $ | 8.95 | | | | | | 12/12/2027 | | | | | | — | | | | | | — | | |
| | | | | | 3/7/2019 | | | | | | — | | | | | | 100,000 (12) | | | | | $ | 1.85 | | | | | | 3/7/2029 | | | | | | 18,000 (13) | | | | | $ | 135,900 | | |
|
Sandra Hatten
|
| | | | 6/26/2015 | | | | | | 100,000 | | | | | | — | | | | | $ | 21.67 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | | 12/10/2015 | | | | | | 50,000 | | | | | | — | | | | | $ | 14.35 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | | 12/14/2016 | | | | | | 60,000 | | | | | | — | | | | | $ | 10.40 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | | 12/12/2017 | | | | | | 30,000 | | | | | | — | | | | | $ | 8.95 | | | | | | 2/29/2020 | | | | | | | | | | | | | | |
| | | |
Option Awards
|
| |
Share Awards
|
| ||||||||||||||||||
|
Name
|
| |
Number of
shares acquired on exercise (#) |
| |
Value
realized on exercise ($) |
| |
Number of
shares acquired on vesting (#) |
| |
Value
realized on vesting ($) |
| ||||||||||||
|
Gregory J. Divis
|
| | | | — | | | | | | — | | | | | | 15,000 | | | | | | 114,300 | | |
|
Michael F. Kanan
|
| | | | — | | | | | | — | | | | | | 12,000 | | | | | | 91,440 | | |
|
Thomas S. McHugh
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
|
Jordan S. Dubow, M.D.
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
|
Phillandas T. Thompson
|
| | | | — | | | | | | — | | | | | | 12,000 | | | | | | 91,440 | | |
|
Sandra Hatten
|
| | | | — | | | | | | — | | | | | | 8,333 | | | | | | 63,497 | | |
|
Name
|
| |
Cash
Payment ($) (1) |
| |
Value of
Benefits ($) (2) |
| ||||||
|
Gregory J. Divis
|
| | | $ | 798,000 | | | | | | 33,043 | | |
|
Michael F. Kanan
(3)
|
| | | $ | 408,718 | | | | | | 20,279 | | |
|
Thomas S. McHugh
|
| | | $ | 385,000 | | | | | | 22,028 | | |
|
Jordan S. Dubow, M.D.
|
| | | $ | 445,875 | | | | | | — | | |
|
Phillandas T. Thompson
|
| | | $ | 392.400 | | | | | | 7,099 | | |
|
Sandra Hatten
(4)
|
| | | $ | 323,092 | | | | | | 13,521 | | |
|
Name
|
| |
Cash
Payment ($) (1) |
| |
Value of
Benefits ($) (2) |
| |
Acceleration
of Equity Awards ($) (3) |
| |||||||||
|
Gregory J. Divis
|
| | | $ | 798,000 | | | | | | 33,043 | | | | | | 3,116,900 | | |
|
Thomas S. McHugh
|
| | | $ | 385,000 | | | | | | 22,028 | | | | | | 1,025,000 | | |
|
Jordan S. Dubow, M.D.
|
| | | $ | 445,875 | | | | | | — | | | | | | 2,077,400 | | |
|
Phillandas T. Thompson
|
| | | $ | 392.400 | | | | | | 7,099 | | | | | | 751,200 | | |
| | | |
Fiscal Year Ended
December 31, |
| |||||||||
| | | |
2019
|
| |
2018
|
| ||||||
|
Audit Fees
|
| | | $ | 1,559,100 | | | | | $ | 1,582,054 | | |
|
Audit-related Fees
|
| | | | — | | | | | | — | | |
|
Tax Fees
|
| | | | — | | | | | | — | | |
|
All Other Fees
|
| | | | — | | | | | | — | | |
|
Total Fees
|
| | | $ | 1,559,100 | | | | | $ | 1,582,054 | | |
| | | |
Share Awards
|
| |||||||||
|
Name and Position
|
| |
Dollar Value
($) (1) |
| |
Number of
Awards (#) |
| ||||||
|
Gregory J. Divis,
Chief Executive Officer
|
| | | | 1,060,640 | | | | | | 112,000 | | |
|
Thomas S. McHugh
|
| | | | 378,800 | | | | | | 40,000 | | |
|
Jordan S. Dubow, M.D.
|
| | | | 378,800 | | | | | | 40,000 | | |
|
All current executive officers, as a group
|
| | | | 1,818,240 (2 ) | | | | | | 192,000 | | |
|
All current employees who are not executive officers, as a group
|
| | | | 1,184,697 (2 ) | | | | | | 125,100 | | |
|
Plan category
|
| |
Number of securities to
be issued upon exercise of outstanding options, warrants and rights |
| |
Weighted-average
exercise price of outstanding options, warrants and rights |
| |
Number of securities
remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) |
| |||||||||
| | | |
(a)
|
| |
(b)
|
| |
(c)
|
| |||||||||
|
Equity compensation plans approved by security holders
|
| | | | 5,759,000 | | | | | | 7.84 | | | | | | 565,716 | | |
|
Equity compensation plans not approved by security holders
|
| | | | — | | | | | | — | | | | | | — | | |
|
Total
|
| | | | 5,759,000 | | | | | | 7.84 | | | | | | 565,716 | | |
No information found
* THE VALUE IS THE MARKET VALUE AS OF THE LAST DAY OF THE QUARTER FOR WHICH THE 13F WAS FILED.
| FUND | NUMBER OF SHARES | VALUE ($) | PUT OR CALL |
|---|
| DIRECTORS | AGE | BIO | OTHER DIRECTOR MEMBERSHIPS |
|---|
No information found
No Customers Found
No Suppliers Found
Price
Yield
| Owner | Position | Direct Shares | Indirect Shares |
|---|