UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form
(Mark One)
REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 |
OR
ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the fiscal year ended
OR
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the transition period from to .
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SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
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Federal Republic of
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Tel: +49 40 560810
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(Name, Telephone, E-mail and/or Facsimile number and Address of Company Contact Person)
Securities registered or to be registered pursuant to Section 12(b) of the Act.
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☐ Item 17 ☐Item 18
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F. | Disclosure of a registrants’ action to recover erroneously awarded compensation. | 87 |
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Item 14. Material Modifications to the Rights of Security Holders and Use of Proceeds. | 109 | |
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Management’s annual report on internal control over financial reporting. | 110 | |
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Item 16D. Exemptions from the Listing Standards for Audit Committees. | 113 | |
Item 16E. Purchases of Equity Securities by the Issuer and Affiliated Purchasers. | 113 | |
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TRADEMARKS, SERVICE MARKS AND TRADE NAMES
Evotec, the Evotec SE logo, EVT, ScreenSeq, ScreenPep, PanHunter, Just, the Just logo, J.POD, J.HAL, J.HAL HUMANOID ANTIBODY LIBRARY, JP3, Aptuit, the Aptuit logo, Evotec INDiGO, Aptuit INDiGO, Cyprotex and other trademarks or service marks of Evotec appearing in this annual report are the property of the Company. Solely for convenience, some of the trademarks, service marks, logos and trade names referred to in this annual report are presented without the ®, ™ or SM symbols, but such references are not intended to indicate, in any way, that we will not assert, to the fullest extent under applicable law, our rights or the rights of the applicable licensors to these trademarks, service marks and trade names. This annual report contains additional trademarks, service marks and trade names of others. These trademarks, service marks and trade names may be the property of their respective owners. We do not intend our use or display of other companies’ trademarks, service marks, copyrights, or trade names to imply a relationship with, or endorsement or sponsorship of us by those companies.
PRESENTATION OF FINANCIAL INFORMATION
The consolidated financial statements have been prepared in accordance with International Financial Reporting Standards (“IFRS”) and its interpretations as issued by the International Accounting Standards Board (“IASB”), as adopted by the European Union (“EU”) and additionally as issued by the IASB. Our financial information is presented in Euros. For the convenience of the reader, we have translated some of our financial information into U.S. dollars. Unless otherwise indicated, these translations for the financial information as of and for the years ended December 31, 2024 and 2023 were made at the rate of €1.00 to $1.0389 obtained from the European Central Bank on December 31, 2024. The exchange rate is based on a regular daily concentration procedure between central banks across Europe and worldwide, which normally takes place at 2:15 pm Central European Time. Such U.S. dollar amounts are not necessarily indicative of the amounts of U.S. dollars that could have been purchased upon exchange of Euros at the dates indicated. All references in this annual report to “$” mean U.S. dollars and all references to “€” mean Euros. Throughout this annual report, references to “ADSs” mean American Depositary Shares or ordinary shares represented by American Depositary Shares, as the case may be.
CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS
This annual report contains forward-looking statements concerning our business, operations and financial performance and condition, as well as our plans, objectives and expectations for our business operations and financial performance and condition. Many of the forward-looking statements contained in this annual report can be identified by the use of forward-looking words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,” “target,” “would” and other similar expressions that are predictions of or indicate future events and future trends, although not all forward-looking statements contain these identifying words.
Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to a variety of factors, including, but not limited to, those identified in the section titled “Risk Factors” in this annual report. The forward-looking statements in this annual report include, among others, statements regarding:
| ● | Our ability to innovate sufficiently and continually remain at the forefront of precision medicine, including with respect to our platform technologies and our investment into the discovery of new pipeline assets, such that we retain our existing customers, broaden, and deepen our customer relationships and gain new customers, |
| ● | Our ability to find suitable partners or agree on acceptable terms regarding our unpartnered pipeline assets, |
| ● | The ability and timing of our partners to develop successfully, conduct trials of, obtain regulatory approval for and commercialize our pipeline assets, |
| ● | Our ability to allocate resources properly, retain the business of our existing customers, and successfully manage the expansion of our company, including with respect to our investments, |
| ● | Whether we can obtain a positive return on our equity investments, |
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| ● | The impact of any pandemic similar to the COVID-19 pandemic, epidemic or outbreak, on our business, financial condition, results of operations, cash flows and prospects, |
| ● | The Russia-Ukraine war and all its potential impacts such as significantly increasing energy prices and transport costs as well as supply bottlenecks and delays, growing risks of cyber-attacks, and risks of production interruptions at our sites, particularly because of restricted energy supplies. The impact on our results of operations and cash flows from period to period is affected by fluctuations in foreign exchange rates, |
| ● | Our ability to comply with the applicable laws and regulations, export and import controls, sanctions, embargoes, anti-corruption laws and anti-money-laundering laws and Sarbanes-Oxley Act (“SOX”), |
| ● | Our ability to secure our information technology systems and the data stored therein, and prevent and remediate cyber-security incidents, |
| ● | Our ability to obtain potentially substantial additional financing required to achieve our goals, |
| ● | Our ability to take advantage of Research & Development (“R&D”) tax credits, grants, and tax loss carryforwards, and |
| ● | Our ability to obtain sufficiently and timely, maintain, protect, defend and/or enforce our intellectual property rights. |
The preceding list is not intended to be an exhaustive list of all our forward-looking statements. The forward-looking statements contained in this annual report speak only as of the date of this annual report, and unless otherwise required by law, we do not undertake any obligation to update them considering new information or future developments or to release publicly any revisions to these statements to reflect later events or circumstances or to reflect the occurrence of unanticipated events.
In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based upon information available to us as of the date of this annual report, and while we believe such information forms a reasonable basis for such statements, such information may be limited or incomplete. Our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of all potentially available relevant information. These statements are inherently uncertain, and investors are cautioned not to unduly rely upon these statements.
Summary of Risks Associated with our Business
Our business is subject to several risks which you should be aware of before making an investment decision. These risks are discussed more fully in the section of this annual report titled “Risk Factors”. These risks include, but are not limited to, the following:
| ● | Our business is subject to the significant and increasing challenges that face the pharmaceutical and biotechnology industries, |
| ● | Our business depends on our and our partners’ success in innovation and drug development, which is highly uncertain, |
| ● | Drug discovery and innovation are subject to significant risks and increasing challenges, |
| ● | Our operational business faces various performance-related risks, |
| ● | Our company intends to develop and expand, which may encounter difficulties in managing our development and expansion efforts, which could disrupt our operations, |
| ● | Our success depends on our ability to attract and retain senior management and key employees, including highly specialized scientific staff, |
| ● | Our partners and we face intense competition in the biotechnology and pharmaceutical industries, also through technical developments, |
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| ● | The approval and sale of drug products are subject to extensive regulation, and accordingly our ability to generate revenue from our pipeline assets is uncertain, |
| ● | Even if any of our pipeline assets are commercialized, they may not be accepted by physicians, healthcare payors, patients, or the medical community in general, |
| ● | Our ability to comply with the applicable laws and regulations, export and import controls, sanctions, embargoes, anti-corruption laws, anti-money-laundering laws and SOX, |
| ● | Geopolitical uncertainties such as the Russia-Ukraine war, the Middle East conflict or an increasing escalation and expansion of the trade conflict between the USA and China with all its implications and effects - such as for example uncertainties in energy markets, supply bottlenecks, and increasing risks of cyber-attacks, |
| ● | Our ability to fulfill all national and international regulations related to sustainability and environmental, social and governance (“ESG”) expecting us to identify, prevent, mitigate and ideally eliminate the extent of potential negative impacts or violations throughout our business activities and value chain, |
| ● | Our efforts to obtain, maintain, protect, defend and/or enforce our intellectual property may be inadequate and our business could be adversely affected as a result, |
| ● | Our activities, and the activities of our customers, to comply with extensive government regulations to ensure patient health, and |
| ● | Our ability to accurately report our financial results or prevent fraud if we fail to maintain an effective system of internal control over financial reporting. |
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PART I
Item 1. Identity of Directors, Senior Management and Advisers
A. Directors and senior management.
Not applicable.
B. Advisers.
Not applicable.
C. Auditors.
Not applicable.
Item 2. Offer Statistics and Expected Timetable
A. Offer statistics.
Not applicable.
B. Method and expected timetable.
Not applicable.
Item 3. Key Information
A. [Reserved]
B. Capitalization and indebtedness.
Not applicable.
C. Reasons for the offer and use of proceeds.
Not applicable.
D. Risk factors.
Risk Management
Our business faces significant risks and uncertainties. You should carefully consider all of the information set forth in this annual report and in other documents we file with, or furnish to, the U.S. Securities and Exchange Commission (“SEC”), including the following risk factors, before deciding to invest in or to maintain an investment in our securities. Our business, as well as our reputation, financial condition, results of operations, and share price, could be materially adversely affected by any of these risks, as well as other risks and uncertainties not currently known to us or not currently considered material.
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Strategic risks
Risks from strategic review
Currently, we are undergoing a strategic review, targeted for completion early Q2 2025. The goal is to define a new vision for our company and establish a clear position for the future. During this transitional period, there is a risk of uncertainty both within and outside the organization. This uncertainty could lead to potential delays in work, late decision-making, and unclear priorities. Embarking on a strategic review presents significant opportunities but also entails inherent risks. Failure to execute the strategy effectively could result in a misalignment with our established strengths, such as R&D expertise, scientific excellence and technology leadership potentially diminishing our competitive advantage. Additionally, rapid shifts in the biotech landscape or advancements by competitors during the transformation period could render the new strategy less effective. Further to the strategic review, we will embark on a transformation journey, gaining back our strong and profitable position in the market. While this is clearly needed and expected, the execution will also bear some risks. Poor planning, insufficient resources, or ineffective project management could lead to delays, cost overruns, or incomplete implementation. The transformation may also require substantial investment. If anticipated returns are not achieved, it could strain financial resources and impact long-term sustainability. Furthermore, unsuccessful execution or visible missteps could harm our reputation among investors, partners, and the broader industry. We face potential risks arising from new or changing conditions, developments, and events that could significantly impact our business model and, consequently, our ability to achieve our strategic objectives. Our strategy aims to cover the entire value chain of early research and preclinical development to improve patients’ lives by addressing a broad range of disease areas in collaboration with partners, using a modality-agnostic approach. Failure to successfully execute this strategy could negatively affect our future business performance and market capitalization. The risk of failure to achieve strategic targets depends thereby on internal and external factors.
Macroeconomic risks
We operate in a global environment, making us susceptible to macroeconomic risks that could significantly impact operations, financial performance, and strategic objectives. The ongoing Ukraine-Russia conflict and tensions in the Middle East pose significant risks to global economic stability. These conflicts can disrupt supply chains, increase costs for raw materials, and create uncertainty in key markets. For example, heightened geopolitical instability may lead to interruptions in the availability of critical resources or hinder global transportation networks, delaying delivery timelines and escalating operational expenses. The Ukraine-Russia conflict has already resulted in volatility in energy markets, with Europe being particularly impacted by higher energy prices due to its reliance on natural gas imports. Similarly, instability in the Middle East has the potential to disrupt global oil supplies. Rising energy costs directly affect our operations, especially our higher energy-intensive manufacturing facilities. Changes in trade policies and agreements, particularly following significant political events such as the election of Donald Trump as U.S. president, could introduce new tariffs, trade barriers, or restrictions could impact our business. Uncertainty around trade relationships may result in higher import/export costs for essential materials. The ripple effects of geopolitical conflicts, coupled with broader economic uncertainty, contribute to inflationary pressures that increase the cost of raw materials, labor, and services. Both geopolitical conflicts and evolving trade agreements exacerbate vulnerabilities in global supply chains. Delays or disruptions in sourcing key components, such as reagents, lab equipment, or specialized materials, could significantly impede research timelines or product development efforts.
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Competitors and disruptive market participants
The biotechnology and pharmaceutical industries have experienced rapid growth in recent years but remain intensely competitive. We face the risk that competitors or disruptive market participants may replicate our business model or introduce innovative offerings that could render our services less competitive or even obsolete. Our mission is to discover best- and first-in-class medicines for a broad range of difficult-to-treat diseases in collaboration with our partners. To achieve this, we have developed a comprehensive suite of fully integrated, next-generation technology platforms designed to transform drug discovery and development. These platforms enable significant improvements in drug quality, accelerate the discovery process, and reduce the high attrition costs often associated with traditional methodologies. To remain competitive, we must continuously innovate and provide cutting-edge solutions to its partners. Failure to do so could materially and adversely affect our business. Additionally, industry pressures such as intensified cost-containment measures, particularly on prescription drugs, impact our partners and may indirectly affect us. A contraction in the pharmaceutical and biotechnology industries due to pricing pressures could also materially impact our operations. We consistently invest in the development of cutting-edge technology platforms, services, and products to enhance our competitiveness and differentiation. Risks to keep pace with technological developments, such as the integration of Artificial Intelligence (“AI”) technologies, could result in missed opportunities for automation, predictive analytics, and improved decision-making. For example, a lack of AI-driven systems for compound selection during drug screening could lead to inefficiencies and delays relative to competitors. Shortcomings in these areas could significantly disrupt operations, impair cash flows, and negatively impact our overall business strategy and performance. Competition poses further risks. Superior offerings from competitors could harm our market positioning, revenues, financial conditions, and overall strategy. In 2024, 38,3% of the Company’s revenue came from three customers, and 109 customer alliances each generated over €1 million. Losing key customers to competitors could significantly impact us, especially as competition intensifies from cost-conscious Contract Research Organization (“CROs”) in Asia and Eastern Europe, which offer compelling alternatives for price-sensitive customers. The expansion of pharmaceutical companies into biotech services further increases outsourcing options, while emerging AI-driven biotech’s present growing competitive threats. These AI-focused companies are competing for deals and partnerships with major pharmaceutical firms and may enhance their wet lab capabilities, increasing competition in drug discovery. Our drug discovery and development efforts also face challenges from market players with greater resources or superior manufacturing capabilities. The success of its R&D efforts depends on the competitiveness of its pipeline products against existing or future therapies. If our products fail to stand out, this could increase uncertainty around future cash flows, adversely impacting its financial position and business strategy.
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Partnership risks in Drug development and manufacturing
We face risks to successfully maintain strategic partnerships in drug development and manufacturing due to failure whereas some of the factors of success are beyond our control. For instance, if our customers change their strategic focus, unexpected or unfavorable study results arise, or customers are dissatisfied with our performance under existing agreements, contracts — including those foundational to our strategic relationships with key clients — could be terminated or scaled back with little or no notice. The termination of a major contract or simultaneous delays, cancellations, or conclusions of several agreements could significantly impact our strategic objectives and adversely affect our operating results. Additionally, we could be significantly affected by a decline in research spending by existing or potential customers or a reduction in outsourcing within the biopharma industry. While current market assessments suggest continued recovery, any disruptions could hinder our ability to meet growth expectations. We aim to serve as a source of innovative drug candidates for potential partners. We are advancing multiple active drug discovery and early development projects that we intend to license to partners for clinical development and commercialization. However, our strategic growth goals could be jeopardized by the fact that some of its projects remain unpartnered. If we fail to secure suitable partners or agree on acceptable terms, the company may be unable to generate returns from these projects. Moreover, changes in the commercial priorities of our partners could lead to strategic re-prioritizations or the discontinuation of certain projects or partnerships. In such cases we would assume the risks associated with further development and re-partnering efforts. A failure to secure new partners could result in additional costs and the loss of potential revenue streams, undermining the ability to achieve our strategic objectives. Pharmaceutical and biotech companies are increasingly outsourcing drug development and manufacturing to Contract Development and Manufacturing Organization (“CDMOs”) to reduce costs, access specialized expertise, and accelerate time-to-market. With Just – Evotec Biologics, we strategically focus on providing development and manufacturing services for antibodies, next-generation biologics, and biosimilars. Our innovative, integrated end-to-end continuous manufacturing platform is highly intensified, enabling significantly higher productivity within a smaller footprint compared to traditional batch manufacturing. Maturing into a late stage/commercial CDMO will allow us to leverage larger-scale operations to lower production costs, benefiting our clients. Additionally, our ability to scale production flexibly based on client needs during product launch, growth, or sunset phases positions us for long-term partnerships with significant financial potential for the company. However, risks remain. Inspection and approval of United States (“US”) sites by the U.S. Food and Drug Administration (“FDA”) is dependent upon our client base and their progression through drug development inclusive of late-stage clinical trials. Internally, failing to meet client timelines, insufficient resources like raw material delays, technical batch failures, or the loss of key personnel could hinder progress in our business, potentially increasing costs. Externally, clients may adjust portfolios or terminate partnerships for financial or market reasons, posing immediate financial risks. These challenges could impact our strategic objectives, reputation, and long-term financial targets.
Commercial risk from out licensing and licensed products
We depend in part on out-licensing arrangements for late-stage development, marketing, and commercialization of our pipeline assets. Dependence on out-licensing arrangements subjects us to several risks, including the risk that we have limited control over the amount and timing of resources that our licensees devote to pipeline assets, that our licensees may experience financial difficulties or that our licensees may fail to secure adequate commercial supplies of pipeline assets upon marketing approval. Moreover, we face the risk that our future revenues depend on the efforts of our licensees and that business combinations or significant changes in a licensee’s business strategy may adversely affect the licensee’s willingness or ability to complete the development, marketing and/or commercialization of the relevant pipeline assets. Finally, a licensee could move forward with a competing product candidate developed either independently or in partnership with others, including our competitors. If we or any of our licensees’ breach or terminate their agreements with us if any of our licensees otherwise fail to conduct their development and commercialization activities in a timely manner or if there is a dispute about their obligations, we may need to seek other licensees, or we may have to develop our own internal sales and marketing capability for our pipeline assets. Our dependence on our licensees’ experience and the rights of our licensees could limit our flexibility in considering alternative out-licensing arrangements for our pipeline assets. Any failure to successfully develop these arrangements or failure by our licensees to successfully develop or commercialize any of our pipeline assets in a competitive and timely manner will have a material adverse effect on the commercialization of our pipeline assets.
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Financial risks
Liquidity risk
Revenue fluctuations, expenditures, external events, and changes in the business environment might negatively impact our short-to-medium term profitability and liquidity. We participate in scientific projects with milestone character in order to benefit financially from high success or specific results. However, these are usually linked to the successful achievement of an important scientific result or regulatory event, so that the outcome is uncertain due to the nature of scientific research and development. Therefore, despite our best efforts, there is a risk that these milestones will not be reached or will be reached later than planned, which may have a negative effect on the planned liquidity and margin. We may also be exposed to liquidity risks from long-term fixed-price contracts if the planned cash inflows in connection with these contracts are lower than expected and if cost increases (e.g. inflation) were not sufficiently factored in and negotiated when the contracts were concluded. As of December 31, 2024, we had €396.8 million in cash, cash equivalents and investments. However, our operating plan may change as a result of many factors currently unknown to the us, and we may need to seek additional funds sooner than planned, through public or private equity or debt financings, government or other third-party funding, sales of assets, other partnerships and licensing arrangements, or a combination of these approaches. Even if we believe to have sufficient funds for the current or future operating plans, we may seek additional capital if market conditions are favorable or if we have specific strategic considerations. Our spending will vary based on new and ongoing development and corporate activities. At the end of 2022, we were able to secure €150.0 million in additional financing from the European Investment Bank (“EIB”). By the end of 2024, we drew €93.3 million of this loan to finance our research. Overall, we believe to have sufficient liquidity to meet liabilities when due, under both normal and stressed conditions, without incurring unacceptable losses or risking damage to its reputation. Interest risks may arise from inevitable negative development of market interest rates. The increase in interest rates affects the interest charges on our variable interest-bearing loans and leads to additional interest expenses. At the end of 2024, 5% of our loans have variable interest conditions. Therefore, the interest rate risks on loans can be considered immaterial. We regularly maintain cash balances at third-party financial institutions in excess of applicable insurance limits and are therefore reliant on banks and other financial institutions to safeguard and allow ready access to the assets. If banks or financial institutions enter receivership or become insolvent in the future in response to financial conditions affecting the banking system and financial markets, our ability to access our existing cash, cash equivalents and investments may be threatened. In July 2024, the Company secured a €250 million senior secured revolving credit facility (“RCF”) to strengthen its liquidity position, supporting investments, working capital needs, and future growth. The RCF was intended as a backup credit line rather than a critical financing instrument. In the third quarter of 2024, we revised our financial performance guidance for the year, which created unexpected pressure on our debt covenants, including the net debt leverage covenant associated with the newly signed RCF. Draw stop and covenant waiver remain in place until us and our lenders renegotiate the RCF terms, reflecting the updated credit situation, in the second half of 2025. The liquidity risk resulting from the draw stop is limited, as we maintain sufficient operational liquidity to cover our funding needs for the year 2025.
Currency risks
Our business and reported profitability are affected by fluctuations in foreign exchange rates mainly between the US dollar, Pound Sterling and the Euro. We manage the currency risks via close market monitoring, forward rate agreements, natural hedges and other selective hedging instruments. Hedging transactions are entered into for future transactions that can be reliably anticipated based on our order book. Despite active currency management, exchange rate risk cannot be fully eliminated due to unpredictable volatility. As a result, our business may be affected by fluctuations in foreign exchange rates, which may have a significant impact on the results of operations and cash flows from period to period. Currency exchange movements also impact our reported liquidity in respect of translating liquid assets held in US dollars (approximately 26% of our liquid assets) or pound sterling into Euros. In the course of 2024 we have slightly reduced our currency exposure. On December 31, 2024, 62% of the Liquidity is held in EUR.
Legal/compliance risks
Litigation and contractual risks
We are exposed to risks from litigation and cannot completely rule out infringements of legislation or regulations. As a result, we are exposed to the potential risk that legal action, court rulings or out-of-court settlements may have adverse financial consequences. We are bound by numerous contracts with a high degree of standardization, in particular customer contracts under which we are providing services. Some of the contracts, in particular collaboration agreements with other partners, are more complex and have a lower degree of standardization. Contractual clauses which, after final negotiation with the partner, are rather unfavorable for us may entail contractual risks like legal liability risks and financial risks. Risks may also arise if the parties interpret a contractual clause differently than we intended. We have not recorded any judicial or material out-of-court settlements with customers in the past 10 years, so we consider the risk to be low.
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Regulatory risks
We and our pharmaceutical and biotechnology customers and partners are subject to extensive regulations by the FDA and similar regulatory authorities in other countries for development, manufacturing and commercializing products for therapeutic or diagnostic use. Such regulations include but are not limited to, restrictions on testing on animals and humans, manufacturing, safety, efficacy, labelling, sale, advertising promotion and distribution of our or our partners’ products. In addition, new laws and regulations to which we and our customers and partners are subject may change in the future affecting the viability of market entry for new products developed by us or the ability to continue certain projects for our customers and partners that may consequently be terminated at an early stage.
Regulations related to sustainability and environmental, social and governance (“ESG”) topics have become increasingly important for companies in the recent years and are subject to rapid and ongoing development. Due to the growing report requirements with the EU Taxonomy, the Supply Chain Act and currently applicable Corporate Social Responsibility Directive Implementation Act (“CSR-RUG” - German: CSR-Richtlinie-Umsetzungsgesetz) the scope of reporting is increasingly large. Moreover, the Corporate Sustainability Reporting Directive (“CSRD”) was expected to be adopted for companies meeting certain criteria related to size and revenues, such is Evotec, to replace the CSR-RUG in Germany as of financial year 2024 onwards. Surprisingly it has not been passed by the German Parliament in 2024. The legal insecurities resulting from this also cause challenges in reporting and reporting compliance. The CSRD will increase the relevance of the information but is also associated with increased additional work due to more complex auditing requirements. This requires enhancing cooperation between internal functions and with that preparation and further provision of capacities within the company. The introduction of the CSRD and thus the European Sustainability Reporting Standards (“ESRS”) was not yet transposed into German law in 2024. This is expected to take place in 2025, meaning that the CSR-RUG currently in force will be replaced from the 2025 financial year. We decided to report for the financial year 2024 voluntarily against CSRD, while making use of the possibility of CSR-RUG to use frameworks for reporting. The information now departs from a compilation of sustainability data to the fact that information requires more strategy and an impact and materiality analysis as a base. The analysis of the impacts now forms the ground of the materiality and thus the material topics that must be reported for companies. This may lead to increased regulatory, social or other scrutiny on our part. Moreover, the EU Taxonomy poses a challenge with the requirements through requiring companies to check their eligibility and alignment with the environmental objectives and disclosing financial key performance indicators (“KPIs”). National and international regulations expect us to identify, prevent, mitigate and ideally eliminate the extent of potential negative impacts or violations throughout our business activities and value chain. If we are not able to adequately meet the statutory reporting obligations and appropriately recognize and respond to the expectations of governments, society and investors with regard to sustainability aspects, we could potentially have to pay significant fines and suffer damage to our reputation. In particular, companies are increasingly being evaluated using their performance on sustainability issues by investors, customers, suppliers and financial institutions. In addition to our own disclosure obligations, compliance with sustainability aspects is assessed by a large number of rating agencies as well as customers. Moreover, sustainability compliance is an increasingly legal obligation for institutional and professional investors, who’s investment decision may be impacted negatively by an inadequate ESG rating. If negative assessments by either of all of the relevant parties were to occur, they could have material adverse effects on our business, financial condition, cash flows and results of operations, and the market value of our common stock could decline. Any failure in this regard could also have a material adverse effect on our reputation and the achievement of our strategic objectives.
The German Supply Chain Due Diligence Act was passed by the German Parliament in 2021 and is mandatory for us from 2024 onwards. This law obliges us to respect human rights and the environment and requires us to implement legally defined due diligence obligations. One of the key elements of these due diligence obligations is the establishment of a risk management system. Such a risk management system is intended to identify, prevent or minimize risks of human rights violations and environmental damage. The due diligence obligations apply both to our own business activities and to the actions of our contractual partners and suppliers. If we fail to comply with the German Supply Chain Due Diligence Act or if supervisory authorities are of the opinion that we have not complied with our due diligence obligations in accordance with this law, this may lead to official enforcement measures or other administrative penalties and fines. This may interrupt or delay our development activities and could have a material adverse effect on our business, financial condition, reputation and results of operations.
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Product liability risks
It is possible that we will be responsible for potential product liability stemming from product research, development or manufacturing and may face an even greater risk if any drug candidate that we develop is commercialized. If we cannot successfully defend ourselves against claims that drug products we develop with our partners caused injuries, we could incur substantial liabilities. Regardless of the merit or eventual outcome of such claims, any liability claims may result in e.g., decreased demand for any drug product that we may develop with our partner, loss of revenues, significant time and costs to defend the related litigation, initiation of investigations by regulators and injury to our reputation and significant negative media attention. We are covered by liability insurance, but notwithstanding such coverage our financial position or results could be negatively affected by product liability claims. On occasion, large judgments have been awarded in class action lawsuits based on drugs or medical treatments that had unanticipated adverse effects.
Quality risks in manufacturing and R&D
Our business success hinges upon the fulfillment of both our own and legal quality standards. Parts of our operations are subject to current Good Manufacturing Practice (“cGMP”), Good Laboratory Practice (“cGLP”) and Good Clinical Practice (“cGCP”) requirements. Regulatory authorities and our customers may conduct scheduled or unscheduled (for cause) inspections of our facilities to monitor its Quality System and verify that it complies with regulatory requirements and with the terms of our quality agreements with our customers. Audit findings that can impact on patient’s safety, are classified as “critical” and may lead to a loss of certification with regulatory agencies or a loss of approved supplier status with our customers and a subsequent loss in revenues and in reputation. Our manufacturing facilities also require certification and validation activities to demonstrate that they operate as designed. In addition, our manufacturing and testing facilities are subject to regulatory inspections by the national competent authorities in EU member states (including Italian Medicines Agency (“AIFA”) and Minister of Health in Italy), the Medicines and Healthcare products Regulatory Agency (“MHRA”) in the United Kingdom, the FDA, and other comparable regulatory authorities of other countries. If we are unable to reliably conduct the preclinical and clinical study and manufacture products in accordance with the regulatory requirements, we may not obtain or maintain the necessary authorizations. Further, our facilities may fail to pass regulatory inspections, which would cause significant delays and additional costs required to remediate any deficiencies identified by the regulatory authorities. In addition, any failure of quality in the product could cause significant delays and additional costs required to remediate any deficiencies. Any failure in quality which can cause damage to the patient may be subject to civil and criminal penalties. Any of these challenges could delay completion of clinical trials, require bridging clinical trials or the repetition of one or more clinical trials, increase clinical trial costs, delay regulatory approval, impair commercialization efforts, increase our cost of goods, and have an adverse effect on our business, financial condition, results of operations and growth prospects. With reference to all activities performed in research or non-Good x Practice (“GxP”) development phases, a lack of quality can bring to generation of unreliable data, with consequent loss of time to repeat the experiments, increase of cost, loss of revenues and loss of reputation.
General Governance and compliance risks (fraud, corporate governance)
In terms of governance and compliance risks, we are exposed to a variety of potential challenges, including bribery and corruption, antitrust violations, internal and external fraud, data protection breaches, unlawful public disclosure of insider information, non-compliance with the Supply Chain Due Diligence Act (“SCDDA”), product liability, conflicts of interest, and emerging regulations such as the AI Act. The risks vary in their level of significance and potential impact on the company and have the potential to harm our reputation and result in financial penalties.
Our employees are obliged to adhere to our Code of Ethics and Business Conduct, which is applicable across the entire group. Compliance with internal company policies is paramount to our success and ensures a safe work environment for our employees and early detection of potential risks. It is essential for us to ensure that we in general and our employees individually conduct business in a legal, ethical and responsible manner. Employees are obliged to report any incidents they suspect of having breached the ethical guidelines laid out in our Code of Conduct to their supervisor or to our Compliance Officer. We have also established appropriate guidelines and processes with regard to insider regulations. Accordingly, investigations regarding certain transactions in our shares by our former Chief Executive Officer (“CEO”) were directed exclusively against the person concerned and not against us. Our corporate Legal & Compliance department is in charge of compliance monitoring.
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Risks of failing to maintain effective internal control over financial reporting as a U.S.-listed company.
We have identified material weaknesses in our internal control over financial reporting as of December 31, 2024. We are subject to requirements under the Sarbanes-Oxley Act of 2002, as amended (“Sarbanes-Oxley”), to perform system and process evaluation and testing of our internal control over financial reporting to allow management to assess the effectiveness of our internal controls. Management has identified material weaknesses in our internal control over financial reporting. As a result, management has concluded that, as of December 31, 2024, our internal control over financial reporting was not effective, as more fully described in Item 15. E of this annual report. Management has also accordingly concluded that our disclosure controls and procedures were not fully effective.
Notwithstanding the material weaknesses, we confirm that our consolidated financial statements, as included in this annual report, fairly present, in all material respects, our consolidated financial condition as of December 31, 2024 and our consolidated results of operations and cash flows for the year ended December 31, 2024, in conformity with IFRS. Management has developed a remediation plan to address the material weaknesses, including enhancing the risk and control frameworks, which will build on the significant attention that management has devoted to controls to date. While we are taking steps to address these material weaknesses, which could require us to expend significant resources to correct the material weaknesses or deficiencies, any gaps or deficiencies in our internal control over financing reporting may result in us being unable to provide required financial information in a timely and reliable manner and/or incorrectly reporting financial information, which could reduce confidence in our published information, impact access to capital markets, impact the trading price of our securities or subject us to potential regulatory investigations and sanctions. In addition, there can be no assurance that these measures will remediate the material weaknesses in our internal control over financial reporting or that additional material weaknesses in our internal control over financial reporting will not be identified in the future. Any of the foregoing could materially and adversely affect our business, results of operations and financial condition.
Risks of changes in tax laws and interpretations by authorities
We operate in many different jurisdictions and are exposed to various tax risks. Key factors contributing to this risk include legislative changes, where amendments to tax laws and regulations in countries where we operate can impact our tax obligations. These changes may include adjustments to corporate tax rates, introduction of new taxes, or modifications to existing tax incentives. Interpretation by authorities is another factor, as tax authorities may interpret laws and regulations differently, leading to disputes and potential adjustments to our tax filings, resulting in additional tax payments and legal costs. Audit risks are also significant, as increased scrutiny and audits by tax authorities can uncover discrepancies or differing interpretations, leading to reassessments and additional tax liabilities. Transfer pricing adjustments can affect the allocation of income and expenses among subsidiaries, impacting our overall tax burden. Additionally, inconsistent application of double tax treaties can lead to double taxation, where the same income is taxed in multiple jurisdictions.
Loss of R&D tax credits
We rely significantly on Research & Development (“R&D”) tax credits to support our innovation and development activities (as of December 31, 2024, we received € 46.9 m in R&D tax credits for that year). These credits can be subject to change based on government policies and economic conditions in the countries where we operate. The potential reduction or elimination of R&D tax credits could result in increased tax liabilities and reduced cash flow, adversely affecting our financial performance and ability to invest in future R&D projects. Factors contributing to this risk include: Changes in legislation (amendments to tax laws or regulations that reduce or eliminate R&D tax incentives), Economic Downturns (governments may alter tax policies in response to economic challenges, impacting the availability of R&D credits), Compliance and Audit Risks (increased scrutiny and audits by tax authorities could lead to disallowance of claimed credits), Global Operations (variations in tax policies across different jurisdictions where we operate can create uncertainty and complexity in claiming R&D credits).
Ownership and patent risks
If our business activities conflict with patents or other intellectual property rights of third parties, activities may be suspended or there may be a legal dispute. Also, if we believe that our patents or other intellectual property rights have been infringed upon by a third party, we might file lawsuits. These actions could have an influence on our financial position or results.
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Uncertain protection for Evotec´s intellectual property
Our success depends in part on our ability to develop, use and protect its proprietary methodologies, software, compositions, processes, procedures, systems, technologies and other intellectual property. To protect our intellectual property position, we primarily rely upon trade secrets, confidentiality agreements and policies, invention assignments and other contractual arrangements, trademark registrations and copyrights. Although our patent portfolio is not material to certain aspects of our business as a whole, we have filed patent applications in the US, Europe and abroad related to the Company’s pipeline assets, processes or other technologies (including methods of manufacture). Our collaboration partners also file patent applications on their development assets on which we may earn milestones and royalties. We may not be able to apply for patents on certain aspects of our current or future pipeline assets, processes or other technologies and their uses in a timely fashion or at a reasonable cost. Even issued patents may later be found invalid or unenforceable or may be modified or revoked in proceedings before various patent offices or in courts in the US, Europe or other jurisdictions. The degree of future protection for our intellectual property and other proprietary rights is uncertain. Only limited protection may be available and may not adequately protect our rights or permit us to gain or keep any competitive advantage. Additionally, our intellectual property may not provide the us with sufficient rights to exclude others from copying our processes and technologies or commercializing pipeline assets. If we do not adequately obtain, maintain, protect, defend and/or enforce our intellectual property and proprietary technology, competitors may be able to use our proprietary technologies and erode or negate any competitive advantage we may have, which could have a material adverse effect on our financial condition and results of operations.
Risks in a patent prosecution process
The patent application process is subject to numerous risks and uncertainties, and there can be no assurance that we or any of our current or future licensors or partners will be successful in prosecuting, obtaining, protecting, maintaining, enforcing and/or defending patents and patent applications necessary or useful to protect our proprietary technologies (including pipeline assets and methods of manufacture) and their uses. Furthermore, the patent prosecution process is also expensive and time-consuming, and we may not be able to file, prosecute, maintain, protect, defend, enforce or license all necessary or desirable patents or patent applications, as applicable, at a reasonable cost or in a timely manner or in all potentially relevant jurisdictions.
Risks in case of changing patent laws
The patent position of pharmaceutical and biotechnology companies generally is highly uncertain, involves complex legal and factual questions, and has been the subject of much litigation in recent years. Moreover, there are periodic changes in patent law, as well as discussions in the Congress of the United States and in international jurisdictions about modifying various aspects of patent law and such changes in patent laws or in interpretations of patent laws may diminish the value of our intellectual property. There is no uniform, worldwide policy regarding the subject matter and scope of claims granted or allowable in pharmaceutical or biotechnology patents. As a result, the issuance, scope, validity, enforceability, and commercial value of our patent rights are highly uncertain.
Risks in detecting infringement, misappropriation and other violation.
Our ability to enforce our owned (solely or jointly), and in-licensed patent and other intellectual property rights depends on our ability to detect infringement, misappropriation and other violation of such patents and other intellectual property. It may be difficult to detect infringers, misappropriators and other violators who do not advertise the components or methods that are used in connection with their products and services. Moreover, it may be difficult or impossible to obtain evidence of infringement, misappropriation or other violation in a competitor’s or potential competitor’s product or service, and in some cases, we may not be able to introduce obtained evidence into a proceeding or otherwise utilize it to successfully demonstrate infringement. We may not prevail in any lawsuits that we initiate, and the damages or other remedies awarded if we were to prevail may not be commercially meaningful. If any of our owned (solely or jointly) or in-licensed patents covering our pipeline assets, processes or other technologies are narrowed, invalidated or found unenforceable, or if a court found that valid, enforceable patents held by third parties covered one or more of our pipeline assets, processes or other technologies, our competitive position could be harmed or we could be required to incur significant expenses to protect, enforce or defend our rights.
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Risks in securing licenses.
We currently have rights to certain intellectual property, through our owned (solely or jointly) and in-licensed patents and other intellectual property rights, relating to identification and development of our pipeline assets, processes or other technologies. Our pipeline assets, processes or other technologies could require the use of intellectual property and other proprietary rights held by third parties and their success could depend in part on our ability to acquire, in-license or use such intellectual property and proprietary rights. In addition, our pipeline assets may require specific formulations to work effectively and efficiently, and these intellectual property and other proprietary rights may be held by others. We may be unable to secure such licenses or otherwise acquire or in-license from third parties any compositions, methods of use, processes or other third-party intellectual property rights that we identify as necessary or consider attractive, on reasonable terms, or at all, for pipeline assets, processes and other technologies that we may develop. The licensing and acquisition of third-party intellectual property rights is a competitive area, and a number of more established companies are also pursuing strategies to license or acquire third-party intellectual property rights that we, or our partners, may consider attractive or necessary. These established companies may have a competitive advantage over us due to their size, cash resources, and greater clinical development and commercialization capabilities. Any of the foregoing could have a material adverse effect on our competitive position, business, financial conditions, results of operations and prospects.
Third-party challenge to Evotec’s or Evotec’s licensors’ patents
Our owned (solely or jointly) and licensed patents and patent applications may be subject to validity, enforceability, and priority disputes. The issuance of a patent is not conclusive as to its inventorship, scope, validity, or enforceability. Some of our patents or patent applications (including licensed patents and patent applications) may be challenged at a future point in time in opposition, derivation, re-examination, inter partes review, post-grant review or interference or other similar proceedings. Any successful third-party challenge to our or our licensors’ patents in this or any other proceeding could result in the unenforceability or invalidity of such patents, which may lead to increased competition to our business, which could have a material adverse effect on our business, financial condition, results of operations and prospects.
Risks from unknowing all third-party intellectual property rights
We may not be aware of all third-party intellectual property rights potentially relating to our assets. Publications of discoveries in the scientific literature often lag behind the actual discoveries, and patent applications in the US and other jurisdictions are typically not published until approximately 18 months after filing or, in some cases, not until such patent applications issue as patents. We might not have been the first to make the inventions covered by each of our pending patent applications and we might not have been the first to file patent applications for these inventions. To determine the priority of these inventions, we may have to participate in interference proceedings, derivation proceedings or other post-grant proceedings declared by the US Patent and Trademark Office (“USPTO”), or other similar proceedings in non-US jurisdictions (e.g., within the jurisdiction of the Deutsches Patent und Markenamt (“DPMA”) or European Patent Office (“EPO”)), that could result in substantial cost to us and the loss of valuable patent protection. The outcome of such proceedings is uncertain. No assurance can be given that other patent applications will not have priority over our patent applications. In addition, changes to the patent laws of the United States allow for various post-grant opposition proceedings that have not been extensively tested, and their outcome is therefore uncertain. Furthermore, if third parties bring these proceedings against our patents, regardless of the merit of such proceedings and regardless of whether we are successful, we could experience significant costs and our management may be distracted. Any of the foregoing events could have a material adverse effect on the our business, financial condition, results of operations and prospects.
Future litigation by third parties
Our commercial success depends in part on our ability and the ability of future partners to develop, manufacture, market and sell our assets and use our assets and technologies without infringing, misappropriating or otherwise violating the intellectual property rights of third parties. There is a substantial amount of litigation involving patents and other intellectual property rights in the biotechnology industry, as well as administrative proceedings for challenging patents, including interference, derivation, inter partes review, post-grant review, and re-examination proceedings before the USPTO, or oppositions and other comparable proceedings in foreign jurisdictions. We may be exposed to, or threatened with, future litigation by third parties having patent or other intellectual property rights alleging that our assets, manufacturing methods, software and/or technologies infringe, misappropriate, or otherwise violate their intellectual property rights.
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Limited lifespan of patents
Patents have a limited lifespan. Most international jurisdictions provide a 20-year nominal patent term, though many require payment of regular, often annual, annuities to maintain pendency of an application or viability of an issued patent. In some jurisdictions, one or more options for extension of a patent term may be available, but even with such extensions, the lifespan of a patent, and the protection it affords, is limited. Even if patents covering our or our partners’ assets, processes and other technologies and their uses are obtained, once the patent term has expired, we may be subject to competition from third parties that can then use the inventions included in such patents to create competing products and technologies. Any of the foregoing could have a material adverse effect on our competitive position, business, financial conditions, results of operations and prospects.
HR risks
Loss of highly qualified staff (key employees)
In 2024, we faced significant organizational changes and challenges, including the departure of a long-standing CEO, the appointment of an interim CEO, and challenging financial results. These developments necessitated a restructuring program to address capacity issues, which affected approximately 7% of the workforce globally. By the second half of the year, a new CEO and Chief People Officer (“CPO”) were appointed, and a strategic review, led by a newly appointed Executive Vice President (“EVP”), Head of Transformation and Strategy, was launched in October. These challenges significantly impacted Human Resources (“HR”) initiatives, including the temporary suspension of leadership programs (EVOlead) and other talent development activities. We have prioritized our strategy reset, which will drive a revised operating model, organizational structure, culture, and leadership approach. We recognize the heightened risk of attrition, particularly the potential loss of critical talent, which could jeopardize the execution of our new strategy.
Risk related to talent acquisition and employee retention
One of the primary challenges we are facing is sourcing and hiring the right talent across our diverse global locations. This challenge is intensified by competitive labor markets, limited availability of specialized skills, and the evolving demands of the biotech and pharmaceutical industries as we continue to grow and adapt. In addition to sourcing new talent, we must also address the ongoing challenge of replacing employees who leave, retire, or transition out of the organization. Finding suitable replacements, particularly for leadership roles and positions requiring advanced scientific expertise, often requires extended timelines and careful consideration to ensure the right experience, expertise, and cultural fit.
The scarcity of qualified candidates, combined with competition from other industry players and the changing dynamics of remote and hybrid work, can affect our ability to attract talent for critical roles. In 2024, we continued to monitor closely the challenges related to finding new employees and replacements across our global locations. While employee turnover remains a factor in talent management, our ongoing focus is on sourcing and hiring the right talent for key positions. This is particularly important for specialized scientific and leadership roles, where skills shortages and competitive labor markets can lead to prolonged vacancy periods.
Information technology risks
Cyber risks, data integrity and protection and loss of data
We collect and maintain information in digital form that is necessary to conduct our business, particularly for purposes of our PanOmics, PanHunter, J.DESIGN and induced Pluripotent Stem Cell (“iPSC”)-based drug discovery platforms, and we are highly dependent on our information technology systems. In the ordinary course of our business, we collect, store, and transmit large amounts of confidential information, including intellectual property, proprietary business information, human samples and personal information. We have also outsourced elements of our information technology infrastructure, and as a result several third- party vendors may or could have access to confidential information.
Our information technology systems, including its internal computer systems, and data may continue to be vulnerable. As previously disclosed, we were the victim of a ransomware incident in 2023, which may continue to impact our operations. The incident has caused delays in our operations in previous years and may continue to cause delays or loss of revenue and additional costs, which may adversely affect our results of operations, cash flows and financial condition.
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As a result of the ransomware incident and any future cyber security incidents, information stored on our networks may be manipulated, publicly disclosed, and permanently lost. Any such breach or other loss of information could result in legal claims or proceedings and liability under laws that protect the privacy of personal information, as well as regulatory penalties. We cannot guarantee that third parties will not be able to access or otherwise breach our systems without authorization in the future. Such unauthorized access or breach could adversely affect our business, results of operations and financial condition. While we are committed to prevent cyber security incidents, there can be no complete assurance that there will not be future cyber security incidents or vulnerabilities.
Furthermore, because the techniques used to obtain unauthorized access to, or to sabotage, systems change frequently and often are not recognized until launched against a target, we may be unable to anticipate these techniques completely or implement adequate preventative measures in the future as well. We may also experience security breaches that remain undetected for an extended period. If any such material system failure, accident or security breach were to occur and cause interruptions in our operations also in the future, it could result in a material disruption of our development programs and our business operations, whether due to a loss of our trade secrets or other proprietary information or other similar disruptions. Any such breach, loss or compromise of clinical trial participant personal data, including in connection with PanHunter, may also subject us to civil fines and penalties. To the extent that any disruption or security breach were to result in a loss of, or damage to, data or applications, or inappropriate disclosure of confidential or proprietary information, we could incur internal costs or liability, our competitive position could be harmed and the further development and commercialization of our partners’ product candidates could be delayed.
GDPR and other similar jurisdictions
Considering the significantly expanded regulations under General Data Protection Regulation (“GDPR”) and other similar jurisdictions, we are permanently reviewing the handling of relevant internal and external data and its respective flow, storage and access. If we fail to comply with the GDPR and the applicable national data protection laws of the EU member states, or if regulators assert, we have failed to comply with these laws, it may lead to regulatory enforcement actions or other administrative penalties. This may be onerous and may interrupt or delay our development activities, and adversely affect our business, financial condition and results of operations. We must comply with GDPR and United Kingdom (“UK”) GDPR, but the future of UK data protection laws and their alignment with EU standards remains uncertain beyond June 2025, potentially increasing costs and overall risk exposure. New or enhanced privacy and data security laws in jurisdictions outside the EU, including the US, could increase our compliance costs and risks. The EU-US Data Privacy Framework (“DPF”), effective July 2023, establishes safeguards ensuring data protection equivalent to EU standards for companies that join the DPF. While certification under the DPF may lead to additional costs, the penalty risk due to the adequacy decision is considered low, though future challenges to the framework remain a possibility.
Privacy and data security laws, including the GDPR, are rapidly evolving, with significant uncertainty surrounding their enforcement and interpretation. The adoption of the EU AI Act in 2024 introduces new obligations for organizations using AI systems, such as risk classification and safeguards, potentially impacting data protection compliance. Ensuring adherence to these laws and regulations may impose significant costs and risks, potentially disrupting our business, financial results, and prospects.
Operational risks
Procurement risks
Our business depends on a reliable supply of various materials for our laboratories and production. Due to our business model, short-term order inquiries are unavoidable, so that delivery bottlenecks can lead to delays in projects and production and thus have a negative impact on our capacity planning and earnings situation. Price increases for laboratory and production materials, but also for electricity and gas, represent a financial risk. Due to regulatory requirements, however, we are not always able to switch to other sources of supply, so that we cannot fully mitigate the risk. In the context of the Russia/Ukraine conflict and the new rekindled Israel-Hamas conflict with impacts like disrupting the transit via the Strait of Hormuz, we are facing a procurement risk due to short-to-medium-term increasing energy prices since about one third of the gas and oil is transported via that route and would have to be re-routed with impact on increased transportation time, costs and availability of materials and goods. Nevertheless, the risk has decreased compared to 2023, mainly due to the inclusion of additional costs in the budget and a trend towards an easing of the situation on individual procurement markets, particularly the energy market. Despite a positive trend on the energy price market, it remains heavily influenced by political decisions and unpredictable geopolitical developments. Interruptions such as production stop at our sites because of having no materials are therefore currently not predictable.
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Process risks
For the operation of our complex global business, we have opted for a best-of-breed approach, i.e. we use the best system solution for different business processes and connect the various systems using middleware. In this way, we achieve comprehensive coverage of the various business processes and a high degree of accuracy of it. In the past, acquisitions and in-house developments have resulted in a heterogeneous system landscape that does not always support this approach. A heterogeneous process landscape carries the risk that many (financial) processes can involve a high degree of labor-intensive, manual work, which increases the process risk of errors in our day-to-day business. To mitigate this risk, we strive for sustainable automation and digitalization of business processes. The implementation and operation of new processes and IT projects are associated with certain risks. Failure to integrate properly with other systems we use, possible loss of data or information, cost overruns and delays could have a negative impact on our business activities and the effectiveness of our internal controls.
Major disasters on sites
In the event of breakdowns in operations and disruptive major disaster that results in stoppages of our activities on one or multiple sites, or in damages and/or interruptions to the operations of key suppliers, we may be forced to suspend or incur significant delays in parts or all of our activities. In each case, there is a potential risk that our financial position and operating results may be substantially affected. In addition, the timely and proper execution of R&D activities may be impacted by damages to our research facilities or breakdown of production equipment. In case of major unforeseeable disasters such as extreme weather events or earthquakes (especially in risk areas like Seattle, US), we may suffer loss of business due to inability to execute contracts and fulfil client deliverables. We have created business continuity plans as well as disaster recovery plans and have insurances for these rare events.
Environmental, health and occupational safety risks
The nature of our operating activities exposes us to a wide range of environmental, health and safety (“EHS”) risks. Our EHS teams and management systems help identify these risks and drive performance improvements by setting and advising of industry standards, compliance requirements and through minimizing complexity. We continuously enhance governance and competence in EHS across our organization, along with opportunities to focus on proactive risk management, aligned with the global trends, ongoing compliance developments and client expectations in this space.
Item 4. Information on the Company
| A. | History and development of the company. |
We were incorporated on December 8, 1993, as a company with limited liability (Gesellschaft mit beschränkter Haftung) under the laws of Germany under the name EVOTEC BioSystems GmbH, formerly registered with the commercial register (Handelsregister) of the local court (Amtsgericht) of Hamburg, Germany, under the number HRB 54731. On August 7, 1998, we were converted into a German stock corporation (Aktiengesellschaft) under the laws of Germany under the name EVOTEC BioSystems Aktiengesellschaft, formerly registered with the commercial register (Handelsregister) of the local court (Amtsgericht) of Hamburg, Germany, under the number HRB 68223. On February 28, 2002, we changed our name to Evotec OAI AG, and on June 8, 2005, we changed our name to Evotec AG. On March 29, 2019, we converted into a European stock corporation (Societas Europaea, or SE) under the laws of Germany and the EU called Evotec SE, registered with the commercial register (Handelsregister) of the local court (Amtsgericht) of Hamburg, Germany, under the number HRB 156381.
Since November 10, 1999, we have been listed on the regulated market of the Frankfurt Stock Exchange under the trading symbol “EVT” and under the ISIN DE0005664809. Our shares are listed under the Segment Prime Standard.
On November 3, 2021, our registration statement on Form F-1 (File No. 333-260143), as amended, was declared effective by the SEC for our initial public offering of our ADSs, each representing one-half of one ordinary share, no par value per share, pursuant to which we offered and sold a total of 22,995,000 of our ADSs, at a public offering price of $21.75 per share.
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On November 14, 2024, we announced that the Company received a non-binding expression of interest from the listed US biotechnology company Halozyme Therapeutics Inc. regarding a takeover offer addressed to the shareholders of the Company with an offer price of EUR 11.00 per share. On November 22, 2024, we have taken notice of the statement made by Halozyme Therapeutics Inc., stating that it has withdrawn its non-binding proposal to acquire Evotec.
Our principal executive offices are located at Essener Bogen 7, Hamburg, Germany. Our telephone number is +49 40 560 81-0. Our website address is http://www.evotec.com. The information contained on, or that can be accessed through, our website is not incorporated by reference into this annual report. We have included our website address as an inactive textual reference only.
Our agent for service of process in the United States is Evotec (US) Inc., 303B College Road East Princeton, NJ 08540 Tel: (732) 329-2355.
| B. | Business overview. |
At Evotec, we envision drug discovery, development, and manufacturing as a seamless continuum. Our ambition is to lead the way by combining comprehensive disease understanding at the molecular level with cutting-edge technologies, transforming this knowledge into precise, life-changing medicines through collaborative partnerships. We aim for reshaping the future of healthcare through providing flexible access for our partners in the pharmaceutical and biotechnology industry to our platform across the continuum of discovery, development and manufacturing.
As of December 31, 2024, more than 3,800 scientific experts spanning a large range of disciplines along the R&D value chain and in a large variety of disease areas, where we have gained deep knowledge of the underlying biology, molecular mechanisms, and therapeutic targets over the years. Our broad range of disease area expertise covers oncology, central nervous system (“CNS”) disorders, metabolic diseases and cardio-metabolic disorders, auto-immune, inflammatory and infectious diseases, other areas of expertise cover fibrotic and respiratory diseases, rare diseases, and animal health.
Our proprietary technologies and platforms, such as proprietary molecular patient databases, induced pluripotent stem-cell based disease modelling, high performance Omics technologies and comprehensive fully integrated platforms for drug screening, profiling and development as well as manufacturing are setting Evotec apart from competitors. We believe that we differentiate from our competition because we combine technologically leading, fully integrated drug discovery and development platforms with these cutting-edge platforms across a spectrum of modalities. By sharing access to these platforms, we build customized, result-focused partnerships which can be based on standalone and/or integrated fee-for-service relationships with the goal to advance the projects of our partners in the most cost-effective and timely manner to drug candidates with highest probability of success during clinical development and in the market. Furthermore, next generation platforms will be reserved to strategic partnerships where we co-develop assets together with our partners based on proprietary targets or technology platforms. The ultimate goal is to align patients’ needs with the industry’s demand for efficient R&D.
Our network of partners ranges from leading pharmaceutical companies, small and large biotechnology companies, academic institutions, patient advocacy groups and venture capitalists as well as mission-driven foundations and not-for-profit organizations.
Our offering covers all areas of preclinical R&D from Discovery Services to Development & Manufacturing Services as well as Absorption, Distribution, Metabolism, Excretion (“ADME”)-Tox Solutions, provided by our subsidiary Cyprotex. Moreover, we cover the entire value chain of discovery, process development and manufacturing expertise in the field of biologics, operated by Just – Evotec Biologics. By sharing access to these platforms, we form result-driven partnerships to co-create potential drugs and intellectual property by leveraging our assets, targets, and propriety technology platforms together with our partners for co-development or new co-creation of therapeutics.
Artificial Intelligence (“AI”) and Machine Learning (“ML”) expertise and capabilities such as deep learning and computational knowledge integration is put into use where needed and effective along the entire value chain. Our platforms are specifically designed to lead to differentiated results by integration into established R&D capabilities and ultimately for the discovery of next generation, highly differentiated precision medicines.
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For the near future, a substantial majority of revenues (2024: 94%, 2023: 94%) generated from the offerings to our partners will be based on “fee-for-service” agreements or Full-time equivalent (“FTE”) -based arrangements. Subject to the degree of integration of partnerships and multi-step research campaigns, we may also benefit from success-based payments, so-called milestone payments. If alliances are built based on co-development of therapeutics with Evotec Intellectual Property (“IP”) involved, we may also benefit in future from substantial milestone and royalty payments in addition to the compensation of research work via FTE rates. In the years ended December 31, 2023, and 2024, 0.6% and 0.4%, respectively, of our total group revenues from third parties were derived from milestone payments. There was no mentionable contribution of royalties at this stage. Revenues generated from commercial manufacturing of biologics should become a relevant contributor to overall growth of group revenues by 2030.
The chart below provides an overview on active projects/therapeutics, which we co-develop with partners (“Partnered Pipeline”) or which could be subject to co-development alliances in the future (Unpartnered Pipeline”). As of December 31, 2024, the portfolio of projects in clinical trials composed of one drug that obtained market approval in China in 2023 and six projects in Phase I.
We initially discovered most of the candidates for which we have the right to receive royalty or milestone payments. We subsequently licensed or assigned those candidates to partners for continued preclinical and clinical development. Moreover, it also includes candidates that have been initially discovered by our partners and that have become the subject of a joint research project pursuant to which we are eligible for royalty or milestone payments. As of December 2024, 75 active projects were partnered and an additional amount of 45 projects are eligible for partnering in the future. To improve our risk / return profile in future, we will focus on co-developed projects and will pursue independent discovery and development of proprietary asset very selectively as proof-of-concept of our platforms. The only Important to note that the chart above does not contain candidates that are being discovered and developed by partners in whom we have solely an equity stake. For these projects we have no rights to benefit from milestone or royalty payments and there is no direct impact on our P&L. However, we could benefit from value accretion related to the progress of these assets.
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At the start of 2024, we operated 17 sites, including a network of five manufacturing facilities, including capacities for continuous manufacturing of biologics in the United States, in Redmond (Washington), the “J.POD” facility. In September 2024, we celebrated the Grand Opening of our second J.POD facility in Toulouse, France (Europe) which will be operational in 2025. Our Active Pharmaceutical Ingredient (“API”) manufacturing capabilities are in Europe in Abingdon, United Kingdom, and Verona, Italy. We also have GMP manufacturing for cell therapy in Medolla, Italy. In the first half of 2024, we announced a reset of priorities resulting in a stronger focus on profitable growth. This process triggered size and footprint adjustments and led to the exit of our gene therapy activities in Orth, Austria and Chemistry activities in Marcy / Lyon, France as well as the decision to discontinue the operation of Halle / Westphalia, Germany. Eventually, the site in Halle was sold to Monacum Partners GmbH, a Munich based Private Equity firm with closing of the transaction in early December 2024. At the end, of 2024 our local footprint represented 15 sites. Certain of our operations are carried out under GMP and GLP regulations, which are certified and periodically audited by regulatory agencies, such as the FDA, MHRA, AIFA, and our partners.
Starting from January 2024, two new reporting segments were introduced: Shared R&D and Just – Evotec Biologics, replacing EVT Execute and EVT Innovate.
| ● | Shared R&D primarily includes drug discovery and development services and solutions. Starting with sourcing novel treatment ideas derived from patient data and continuing with target validation and lead optimization. In the subsequent development phase selected candidates can seamlessly transition to IND application. Shared R&D accounted for 77% of our revenues from third parties in the year ended December 31, 2024, and 86% and 93% for the years ended December 31, 2023, and 2022, respectively. |
| ● | Just – Evotec Biologics is our advanced approach to designing, discovering, developing, and manufacturing modern bio-therapeutics, provides services in the areas of antibody molecular optimization, first-in-human integrated biologics, product and process design, continuous bioprocessing platforms, and commercial biomanufacturing. Just – Evotec Biologics accounted for 23% of our revenues from third parties in the twelve months ended December 31, 2024, and 14% and 7% for the years ended December 31, 2023, and 2022, respectively. |
Revenue generated through the Evotec or Cyprotex brands are included within the Shared R&D segment, including standard fee-for-service arrangements, larger collaboration arrangements, as well as all pipeline assets. Evotec believes its Shared R&D partnership model is unique and allows to balance and diversify the risks associated with drug discovery. Revenue generated through the Just – Evotec Biologics brand are included within the Just – Evotec Biologics segment.
Our services across the continuum can be clustered in the four areas: Discovery Services, Development & Manufacturing Services, Cyprotex ADME-Tox Solutions, and Just – Evotec Biologics, where the latter represents a separate reporting segment besides Shared R&D, which covers the first three areas. Within our service clusters, we have developed specific areas of expertise and proprietary platforms that are combined with established R&D capabilities designed to offer holistic drug discovery and development solutions.
The composition of revenues and profitability depends on the composition of services provided, the nature of the contract with our partners, the ownership of the intellectual property (i.e. the degree of integration of proprietary technologies and platforms), the stage of the project and our right to generate revenue from development success. We believe our partnership model is unique and allows us to balance and diversify the risks associated with drug discovery.
Discovery Services
Our comprehensive toolbox combines established R&D capabilities and our industrialized PanOmics approach towards molecular disease understanding and iPSC disease modeling platform.
Our integrated Drug Discovery toolbox includes (selection):
| ● | Target ID & Validation |
| ● | Hit Identification |
| ● | Structural Biology |
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| ● | Molecular Design & MedChem |
| ● | In-vitro Biology |
| ● | In-vivo Pharmacology |
| ● | Biomarkers |
| ● | Bioreagents & Cellular Sciences |
| ● | Early Formulation |
| ● | Sample Management |
| ● | In silico and AI/ML platforms |
| ● | Proprietary Technology platforms: PanOmics, Evotec’s Molecular Patient Databases (“E.MPD”), induced pluripotent stem cells (“iPSC”) |
| - | PanOmics- PanOmics, our multi-omics supported drug discovery platform, combines industrialized Omics data generation and AI/ML supported Omics data analysis. Built on the foundation of proprietary molecular patient data, the platform fundamentally improves the understanding of disease processes, disease modeling in vitro and in vivo, the identification of novel high value targets as well as biomarker discovery and patient selection. |
The technologies in use cover the whole range of biomolecules from genes to protein to metabolites. While we are using standard commercially available processes for genomics, we have invested massively into high-throughput and high-resolution transcriptomics, proteomics, and metabolomics methods. These methods allow us to study diseases processes on all molecular levels and yield a deeper understanding of the disease mechanisms and discovery of novel predictive biomarkers. We believe our proprietary multi-omics data generation platform, PanOmics, is industry-leading in terms of throughput, robustness, and cost efficiency, in the fields of transcriptomic and proteomic analysis.
The results often lead to the stratification of sub-populations within a broader group of patients and eventually may lead to the development of personalized therapies. This change in paradigm has increased the need for new AI/ML-based platforms, tools, and methods to better understand, interpret, and translate the vast amounts of information and data that is being generated to broaden knowledge of the molecular biology, cell regulation and the pathogenesis of individual diseases. PanHunter, our integrated data analytics platform, makes the Company’s -omics data available in a user-friendly manner at the enterprise level. Users can freely interact with and combine data in a modular, app-based system where results are available immediately and can be interpreted or used as input for subsequent steps. This rapid feedback is a crucial feature distinguishing PanHunter from other similar tools.
| - | E.MPD - Evotec’s Molecular Patient Databases |
| ● | The drug discovery process starts with a fundamental understanding of molecular disease processes. We believe that gaining a better insight into the molecular level of disease processes is the only way to develop disease modifying or even curative therapies. Evotec has established unique and proprietary molecular patient databases in number of disease areas including chronic kidney disease (“CKD”), immunology and inflammation (“I&I”), and neuronal diseases. Our most comprehensive molecular patient database has been built in CKD. |
Utilizing the PanOmics data generation platforms, we conducted molecular profiling of patient tissues and samples in the database and thereby generated crucial molecular patient data required to drive precision medicine approaches in CKD. We have continuously expanded this database, which is based on data from almost 12,000 CKD patients. To our knowledge, this constitutes by far the largest CKD patient molecular database worldwide and now constitutes more than six hundred billion data points.
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Based on the strength of our molecular CKD patient database, we have built four partnerships in kidney diseases in the last five years with prominent pharmaceutical companies such as Bayer, Novo Nordisk, Eli Lilly, and Chinook (now a Novartis company). Our collaborations are structured as multi-target agreements pursuant to which an undefined number of targets may be pursued.
While our molecular patient database in CKD is the most comprehensive set of data at this stage, we aim to advance several additional proprietary molecular patient databases in other disease areas (e.g., Metabolic and Cardiac diseases, women’s health etc.) by adding samples from more patients. The opportunity to derive new targets and therapies in these disease areas is tremendous, and we aim to capitalize on these databases via additional strategic alliances.
| - | iPSC based disease modeling - The improved molecular understanding of disease processes and therefore of sub-populations of larger patient populations enables us to establish more disease relevant in vitro models especially using patient-derived disease models through iPSC technology. Combining our improved understanding of molecular disease processes in patients with iPSC-based patient derived disease models as well as high performance Omics profiling and AI/ML supported data analytics is a unique set up to seamlessly prosecute novel insights in disease biology into next generation drug discovery programs. |
| ● | iPSC cell assays enable a more accurate modelling of diseases and therefore represent an alternative to animal models in profiling drug candidates at preclinical stages. Patient-derived iPSCs offer unprecedented opportunities for in vitro disease modelling and have unlocked new possibilities for the development of more efficacious and safer drugs. Since 2013, we have built an iPSC infrastructure that forms an integral part of our PanOmics-driven drug discovery platform and can be applied to a broad range of therapeutic areas. It has been created with the key goal of developing more accurate and scalable models to investigate disease aetiology and to industrialize iPSC-based drug screening in terms of throughput, reproducibility and robustness in miniaturized 384-well format. |
While iPSC disease models are traditionally utilized in two-dimensional monocultures, we are also investigating next generation multi lineage technologies, such as co-cultures and organoids, to attain greater physiological relevance. Our ’clinical-trial-in-a-dish’ approach allows testing of novel drug candidates on iPSC-derived models from a representative sample of human patients in a multiplexed fashion and has vast potential for multiple areas of drug discovery – from early stages of lead optimization to regulatory safety assessment.
Development & Manufacturing Services
We provide a one-stop solution for drug development and manufacturing across all stages, designed to work closely together with our partners to design and execute the best strategy for rapid entry into first in human studies and further advancement into clinical supply for Phase II and Phase III studies.
Integrated Development & Manufacturing Services include:
| ● | INDiGO - Investigational New Drug (“IND”) Enabling Program - INDiGO is a fully integrated development program wherein clinical-enabling drug substance, safety assessment, clinical drug product, and regulatory activities are conducted at a single site and within a single contract, providing an fully integrated and optimally-efficient plan for IND/clinical trial application (“CTA”) submission. All these activities are governed by a project team with decades of pharmaceutical experience, and harmonized with our fully-equipped regulatory support team providing a robust, streamlined development engine with multi-disciplinary coordination to accelerate drug candidates into the clinic. Instead of single services, we offer a solution designed to materially shorten the process of bringing a new drug candidate into the clinic. |
| ● | Fully integrated API capabilities - Our API capabilities encompasses process chemistry, analytical, and manufacturing operations. In addition to offering integrated process R&D and analytical development services using state-of-the-art laboratory facilities and equipment, we also supply APIs for preclinical development, non-clinical use, clinical trials, and small-scale commercial supply. To ensure compliance with cGMP standards and to provide support for customer audits and regulatory inspections, we have an independent Quality Assurance unit that oversees all API activities. Our chemistry, analytical, and manufacturing operations are co-located at facilities in Abingdon, UK, and Verona, Italy. |
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| ● | iPSC based Cell Therapy - We have built a fully integrated end-to-end platform to develop and manufacture off-the-shelf iPSC-based cell therapeutics. In addition, we conduct R&D to develop innovative proprietary product candidates to accelerate pipeline building with our partners. Our proprietary internal iPSC-based preclinical product candidate pipeline encompasses immunotherapies for cancer and autoimmune diseases, as well as regenerative therapies targeting diabetes and heart failure. Our platform integrates cutting-edge gene editing and targeting technologies, along with a GMP facility for manufacturing clinical development candidates. located near Modena. |
Cyprotex ADME-Tox Solutions
Cyprotex enables and enhances the prediction of human exposure, clinical efficacy and toxicological outcome of a drug or chemical. We are able to combine quality data from a comprehensive portfolio of in vitro assays with leading in silico technology and harness our extensive experience in the absorption, distribution, metabolism, excretion (“ADME”)-Tox field to add value, context and relevance to the data supplied to our partners. Cyprotex serves a several different industries including the pharmaceutical and biotech, personal care and cosmetics, household products, and the chemical and agrochemical industries.
The range of Cyprotex ADME-Tox Solutions encompasses:
| ● | In vitro ADME and pharmacokinetic (“PK”) - Studying ADME of a compound can be used to estimate the plasma and tissue concentrations in the body (pharmacokinetics). There is a clear link between pharmacokinetics/tissue exposure and clinical efficacy and safety due to either on-target or off-target effects. |
| ● | Integrated and standalone bioanalysis – Evotec and its subsidiaries have a breadth of experience in bioanalysis for small molecules and bio-therapeutics of any size for non-clinical and clinical sample analysis. The scientific experience, capacity and application of the bioanalytical equipment provide a fast turnaround that will help to arrive at “go/no-go” decisions faster. Our bioanalysis service is part of both standalone services as well as fully integrated packages. We can offer both non-GLP and GLP bioanalytical services with validated methods appropriate for regulatory submissions. |
| ● | Toxicology - Significant expertise in the latest techniques such as high content imaging, microelectrode array, 3D cell and iPSC-derived models and transcriptomics to identify potential toxicity and understanding mechanisms of toxicity at an early stage in drug discovery. More and more human relevant cell-based models are being introduced in drug discovery to address this need. Evotec and its wholly owned subsidiary Cyprotex is among the leaders in this field. |
| ● | Physicochemical Profiling - Determining key physicochemical properties of compounds plays a pivotal role in supporting rational compound design by providing insight into the relationship between a molecule’s structure and its physical behavior within many areas in an organism, e.g. dissolution, absorption, distribution, metabolism, elimination, protein affinity, and toxicity. |
| ● | Modelling & Simulation - Properly developed systems models can generate valuable additional information from data, enabling improved decision making, cost reduction and reduction in animal usage. Cyprotex performs innovative mathematical modeling and offers multiple modeling solutions, such as Pharmacokinetic Prediction using physiologically based pharmacokinetic (“PBPK”) models, Machine Learning & Quantitative Structure-Activity Relationship (“QSAR”) /Quantitative structure–property relationships (“QSPR”) modeling primarily performed by a proprietary system developed in-house, PK/pharmacodynamic (“PD”) modeling, as well as a suite of methods for integrating data from multiple in vitro, ex vivo and in vivo sources – whether ADME/PK, toxicity and/or efficacy. |
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Just — Evotec Biologics
Just – Evotec Biologics is our advanced approach to designing, discovering, developing, and manufacturing modern bio-therapeutics. We believe that Just – Evotec Biologics positions us well to establish further significant long-term, integrated partnerships with the expansion of our solutions into highly efficient and flexible biologics manufacturing. This differentiated offering is available to our partners on a fee-for-service and/or FTE-rates-based model as well as through arrangements that involve milestones and royalties.
Evotec acquired Just Biotherapeutics (subsequently renamed Just – Evotec Biologics) in 2019, which represented our entry into the large and growing market for commercial biologics and expanded our multi-modality capabilities. The founding and original concept of Just – Evotec Biologics was to create an agile, flexible, and cost-effective method of biologics discovery, development, and manufacture to enable affordable global access to modern biologics therapies. This powerful, horizontally integrated end-to-end system is called J.DESIGN.
Our full suite of capabilities from Discovery to Commercial Supply of biologics includes:
| ● | Antibody Molecular Optimization |
| ● | Integrated Services for First-in-Human Biologics |
| ● | Development Services |
| ● | Continuous Bioprocessing Platforms |
| ● | Biomanufacturing Services |
| ● | Technology Partnerships |
Because we utilize J.DESIGN throughout the entire drug discovery and development process of a biologic, by the time it reaches the manufacturing stage in any given program, we have already predicted and reduced the risk of most scaling problems that may occur. As a result, we can deliver flexible, right-sized manufacturing with faster turnaround times and without sacrificing the quality of the products. This new paradigm broadens the scope of disease areas for biologic drug candidates driven by significantly higher yields and lower costs. It will also accelerate the growth of biosimilars given cost advantages, and it makes orphan diseases more amenable to biologics despite small addressable populations. For the same reasons, smaller patient populations resulting from precision medicine-based patient stratification will also benefit.
The so called J.POD. a late-stage clinical and commercial manufacturing facility, is the plant design aspect of J.DESIGN. A J.POD accelerates the development of highly productive processes that can be executed in relatively small unit operations and still make enough product to meet almost all commercial market needs in a single facility. These highly intensified processes reduce the size of unit operations to fit into relatively small, flexible “POD’s” or clean rooms, and become the core manufacturing space in a J.POD facility. Since the entire process train uses single-use technology, central and CapEx intense utilities like “clean in place” or “sterilize in place” systems are eliminated, as well as the large amount of stainless-steel piping and large stainless-steel vessels that must be precisely built and validated. In addition, POD’s, and the equipment they contain can be built and assembled while the plant is being constructed so that the time and complexity of validation are dramatically reduced.
Finally, instead of increasing the size of bioreactors and processing steps to expand capacity (as in traditional large-scale manufacturing facilities), additional bioreactors of the same size are essentially “cloned.” In essence, we “scale-out” rather than “scale-up” and effectively reduce scale-up risks by manufacturing at the same scale from early clinical development through commercial manufacturing. Our processes are highly “intensified,” using continuous perfusion and connected downstream processing to make large amounts of high-quality drug substance with a relatively small bio processing footprint.
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To enhance our manufacturing capabilities, in August 2021, we opened our first J.POD, a late-stage clinical and commercial manufacturing facility in Redmond, Washington, United States. Because our facility contains clinical and commercial processes, both can be operated at the same scale to facilitate seamless transfer and eliminate scale-up risk. The site, which will be able to produce on a large enough scale to meet most of our commercial needs in a single facility and will mainly supply markets in North America.
As global demand for flexible biologics capacity and for more affordable access to medicines increases, we have started construction of a second J.POD facility in Toulouse, France in September 2022 and the Grand Opening was celebrated in September 2024.
Our Competitive Strengths
Based on many technological advances and new biological insights, the opportunity to change the odds and improve the success rates in drug discovery has been made more achievable. In our view, our set-up as a fully integrated drug discovery and development innovation hub makes us well-positioned to achieve superior results. We believe we have built the most agile platform in the industry, and we distinguish ourselves from our competition through our competitive strengths, as described below:
| ● | Our fully integrated innovation platform has comprehensive breadth and depth: Our platform covers the full discovery, preclinical and early clinical development value chain, delivered in a highly integrated, cross-functional manner. This platform is comprehensive and, in its breadth, and depth provides unique offering that resonates strongly with our partners because we offer a unique combination of disease area expertise, full-suite technology, and predictive power across most modalities. Our competitors in the market for external drug discovery offer services or solutions with a limited scope focusing on discrete steps within the value chain. In contrast, our platform integrates disruptive, proprietary technologies within a holistic product suite to enable the development of potentially first and best-in-class therapeutics. Based on our industry knowledge and the public disclosure of other industry participants, we believe that we are the only company among our identified competitors that offers chemistry, biology, transcriptomics, proteomics and iPSC-based disease modeling with multi-modality expertise across small molecules, biologics, and cell therapies, as well as related manufacturing capabilities. |
| ● | Our platforms are designed to optimally support precision drug discovery: The integration of precision and efficiency is in our view the solution to the industry’s challenge of constantly declining returns on R&D investments. Over the last 25 years, we have built an agile platform, designed to help improve returns from R&D. Our proprietary discovery and development platforms leverage data, operational efficiencies, and technological capabilities to drive rapid progress and successful outcomes in the early stages of the R&D process. We also apply ML and AI to our novel molecular patient databases and disease models to generate and analyze data with the ambition to increase the likelihood of success in clinical trials and provide solutions to the challenge of constantly declining returns on R&D investments. |
| ● | Our patient-centric approach helps us benefit from the paradigm shift of precision medicine: We have built an advanced precision medicine platform that integrates molecular patient databases, our iPSC- based drug screening platform as well as our PanOmics platforms. We believe that the identification of disease-relevant molecular profiles in patients is fundamental for most precision medicine approaches, and we target the development of molecular patient databases in various disease areas. For example, our chronic kidney disease (“CKD”) database is derived from almost 12,000 CKD patient profiles and more than 6,000 in other disease areas. We have also uniquely integrated our iPSC platform with other core technologies, which enables iPSC-based disease modelling and drug screening at an industrialized scale. We believe that patient-derived disease models are the new gold standard in profiling drugs at the preclinical stage of development, eventually leading to lower attrition rates during clinical trials. This helps us drive the paradigm shift toward individualized drug discovery and allows us to address diseases in a more precise manner tailored to molecular patient profiles. |
| ● | Our modality-agnostic set of solutions maximizes the potential of our integrated technology platform: Our multi-modality platform ranges across small molecules, biologics, and cell therapy. Our platforms are applicable to all modalities and lead to a modality-agnostic pipeline spanning a broad range of disease areas. We leverage our industry-leading iPSC platform for the development of next-generation cell-based therapies as well as disease modeling and drug screening. |
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| ● | Our wide array of high-quality partnerships results in a deep, diversified pipeline: We are a partner of choice for leading pharmaceutical companies, small and large biotechnology companies, start-ups, academic institutions, patient advocacy groups, venture capitalists as well as foundations and mission-driven not-for-profit organizations. Due to our value proposition for partners, we can retain significant commercial upside with all our assets that are partnered in the form of royalties, milestones, or equity stakes. Our pipeline benefits from our highly productive research collaborations and is designed to become one of the largest royalty portfolios in the industry. The value upside created by our pipeline comes at a low capital intensity and at an attractive risk-reward profile as our partners typically carry the clinical development costs of our assets. |
| ● | Our people and culture place scientific excellence at the heart of everything we do: We are led by a strong management team with extensive industry knowledge and experience. We foster a culture of scientific excellence and problem solving, demonstrated by the scientific expertise and passion of our more than 3,800 scientists who work for Evotec as of December 31, 2024. A large share of our employees holds at least one academic qualification, including a significant number with a Ph.D. or equivalent. We stay close to groundbreaking research through our numerous research collaborations with academic institutions such as the University of Oxford, the German Cancer Research Center, (DKFZ), the University Hospital in Hamburg, the University of Toronto, Harvard, Yale, Johns Hopkins University, the Ospedale San Raffaele (OSR) in Milan, or A*STAR and the National University of Singapore (“NUS”). Our people strategy focuses on attracting, growing, and retaining talent, developing our leaders to be great leaders, ensuring a fair and competitive reward system, and supporting our ONE Evotec culture. Our three core values that form the basis of our corporate culture are innovation, collaboration, and entrepreneurship. These values are consistently lived internally amongst Evotec employees as well as externally with our partners (two of our critical stakeholder groups) and are essential to our business model. |
Key Performance Metrics for our Fee-for-Service and FTE-based Business models
| 1) | Share of Annual Repeat Business |
We have demonstrated solid customer retention rates, as defined by the percentage of revenues from customers with whom we had a relationship within the prior year, above 90% in each of the last three years. We review our repeat business on a yearly basis. Repeat business was 94% in 2024, 93% in 2023 and 92% in 2022 respectively.
| 2) | Customer Evolution and Contribution |
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The number of our customer alliances has expanded significantly in recent years, providing further validation of our services provided. The total number of customers in 2024 was 849, compared to 838 in 2023 and 819 in 2022, respectively. During 2024, we added 292 new customers compared to 298 in 2023 and 325 in 2022. The number of customer alliances that generate revenues of more than €1.0 million per year has increased to 109 in 2024 or 13%, whereas in 2023, we had 102 customers or 12% and in 2022 118 or 14% of total customers.
| 3) | Increased revenue share from top ten customers |
Our customer and revenue bases have become more concentrated over the last three years. Our top ten customers’ contribution to total revenues amounted to 52% in 2024 versus 47% in 2023 and 39% in 2022. Evotec’s largest three customers by revenue collectively accounted for 38% of revenues in 2024 versus 35% in 2023 and 25% in 2022. Bristol Meyers Squibb and Sandoz are the only customers which each individually accounted for more than 10% of group revenues.
Our Growth Strategy
Our growth strategy is based on the following pillars:
| ● | Striving for differentiation through technological and scientific leadership. |
| ● | Shared R&D to focus on Drug Discovery & Preclinical Development (Target ID to IND). |
| ● | Just — Evotec Biologics to evolve as technology and service provider and manufacturing accelerator. |
| ● | Focus on high-quality, high-potential. |
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Developments in the pharmaceutical and biotechnology markets
According to Grand View Research, the global biotechnology industry is driven by strong government support in the form of initiatives to modernize the regulatory framework, improvements in approval processes & reimbursement policies, as well as standardization of clinical trials. On the other hand, public funding can be volatile either due to budget constraints or changes in prioritized research fields. A clear driver is the increasing prevalence of personalized medicine and the growing number of orphan drug formulations, which are opening new opportunities for biotechnology applications and are encouraging the influx of emerging and innovative biotechnology companies, further boosting market sales.
Precedence Research estimates the global biotechnology market to grow with a Compounded Annual Growth Rate („CAGR“) of 11.5% from $ 1.55 tn in 2024 to $ 3.21 tn by 2030.
The global small molecule discovery market is expected to increase with a CAGR of 7.97% from $ 88.57 bn in 2024 to $ 140.31 bn by 2030, while the cell therapies continue to become more and more important: The global cell therapy market is expected to grow from $ 21.28 bn in 2024 to $ 58.0 bn in 2030 according to Precedence Research. Rising demand for clinical solutions for the treatment of chronic diseases, such as cancer, diabetes, age-related macular degeneration, and almost all forms of arthritis are also expected to boost the market. The discovery and development of products for diabetes and neurological disorders such as Parkinson’s and Alzheimer’s, various cancers and cardiovascular diseases, together with its partners, is also a core competence of Evotec.
Business model
As an external innovation partner to the life science industry, we provide stand-alone services or integrated offerings, characterized by multi-year, multi-stage drug discovery and development campaigns using our industrialized and comprehensive infrastructure. Strategic pipeline building, leading to co-ownership in drug products, is achieved if proprietary technologies and intellectual property (IP) is leveraged. The “fee-for-service model” is the main source of revenues today. It usually applies where no IP of Evotec is involved or no essential proprietary technology platforms (e.g., PanOmics, iPSC, proprietary molecular patient data) are used. We grant partners access to our own IP and technology platforms only in return for milestone payments or license payments and future royalties in case of commercial success of jointly developed pipeline assets.. These payments are added to FTE-rate based payments for the work required to achieve scientific progress. In the years ended December 31, 2023, and 2024, 0.6% and 0.4%, respectively, of our total group revenues from third parties were derived from milestone payments. There was no mentionable contribution of license payments or royalties at this stage.
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Benefits from our strategy to co-create pipelines include:
| ● | Milestones and royalties-based revenue to secure and accelerate profitability. |
| ● | A risk-reduced development pathway for drugs given the ability to combine Evotec and partner R&D capabilities and expertise. |
| ● | Deepen our knowledge base of high-quality R&D capabilities. |
Evotec ventures: Equity Investments
We have made equity investments in products, technology platforms and companies with the goal to obtain early access to innovation and generate upside through our role as an operational partner and potential preclinical and clinical successes, or even positive commercial developments that could drive the valuation of individual portfolio companies. This could lead to returns on investments in case of successful exits from our portfolio companies. Active management of the portfolio strongly depends on scientific progress of each asset individually. In the meantime, we generate fee-for-service and FTE-rates-based revenues with our portfolio companies. In November and December 2024 we successfully sold all shares in Recursion, which we held since the merger with Exscientia in Q4 2024). Evotec’s equity strategy started with the creation of Evotec’s spinout of Topas Therapeutics in 2016. Since then, our portfolio of equity holdings has grown steadily, and as of December 31, 2024, we have 31 equity engagements in our equity pipeline. Assets from Carrick Therapeutics, Immunitas, Sernova, Topas Therapeutics and Tubulis are the most advanced, with 10 active ongoing clinical trials (Phase I and II). Our ownership ranges from 0.1% to 40% in equity per company. Investments with a share greater than 20% or significant influence are recognized in our accounts “at equity”.
Evotec ventures: Academic BRIDGEs
We believe that academic settings serve as a major source and point of origination and discovery of new targets and drugs. For example, approximately 25% of drugs ultimately approved by the FDA originate from academia, according to a study published by CTS Clinical and Translational Sciences investigating the contribution of different types of organizations to drug innovation. We seek to address the lack of funding and access to expertise for translational projects from academia, which is one of the main hindrances to efficient innovation in drug discovery. Often, there is a lack of commercial understanding on how to advance assets to the next stage. At the same time, there is a need for validation of academic findings on industry-grade platforms to increase data quality and reproducibility, which we address with our Biomedical Research, Innovation & Development Generation Efficiency (“BRIDGE”) model.
Operationally, BRIDGEs fall into two categories: (i) Contractual partnerships with academic institution(s) and investors or pharma companies and (ii) equity investments into start-up studios which focus on accelerating academic projects. To date, we have created eight BRIDGE partnerships (LAB282, LAB150, beLAB2122, beLAB1407, LAB eN², Danube Labs, a BRIDGE with VC Amplitude Ventures, LaB eN2 and 65LAB) and three investments into start-up studios (Autobahn Labs, ArgoBio and Extend). In 2023, Evotec and Novo Nordisk announced LAB eN2,, aiming to nurture early research from academic institutions into novel therapeutics. In November 2023, Evotec expanded beLab1407 BRIDGE with BMS to include three new university partners. In December 2024, we announced the expansion of LAB eN2 to nine top-tier academic institutions including Johns Hopkins University at the US East coast and the launch of three projects from Boston University, Harvard University in collaboration with Mass General Brigham, and Joslin Diabetes Center focusing on cardiometabolic diseases.
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Summary of Equity Holdings, including start-up studios as of December 31, 2024
Company |
| Focus |
| Equity stake |
Aeovian Pharmaceuticals Inc. |
| Inflammatory diseases | % | 3.32 |
ArgoBio SAS |
| Multiple |
| 8.87 |
Aurobac Therapeutics SAS | Antimicrobial Resistance (AMR) | 12.50 | ||
Autobahn Labs, LLC | Multiple | 10.53 | ||
Blacksmith Medicines Inc. |
| Human metalloenzymes |
| 17.97 |
Breakpoint Therapeutics GmbH |
| Oncology (DDR) |
| 34.03 |
Cajal Neuroscience Inc. |
| Neurodegenerative disease |
| 1.58 |
Carma Fund I | Life Science VC | 10.00 | ||
Carrick Therapeutics Inc. |
| Oncology |
| 2.86 |
Celmatix Inc. |
| Women’s health |
| 7.38 |
Centauri Therapeutics Ltd. | Antimicrobial Resistance | 19.37 | ||
Curie Bio LLC | Life Science VC | 0.11 | ||
Curie Bio Seed Fund I LP | Life Science VC | 2.83 | ||
Dark Blue Therapeutics Ltd. |
| Oncology |
| 22.45 |
EIR Biotherapies Srl | Oncology | 39.66 | ||
Eternygen GmbH* |
| NASH |
| 24.97 |
Extend Srl | Multiple | 10.00 | ||
Fibrocor Therapeutics Inc. |
| Fibrotic diseases |
| 8.37 |
Fibrocor LLP |
| Fibrotic diseases |
| 16.26 |
IMIDomics Inc. | Inflammatory diseases | 6.68 | ||
Immunitas Therapeutics Inc. |
| Oncology |
| 5.48 |
Leon Nanodrugs GmbH |
| Nano-technology |
| 10.93 |
Mission BioCapital V LP |
| Life Science VC |
| 3.64 |
OxVax Ltd.* |
| Immuno-Oncology |
| 15.33 |
Pluristyx Inc. |
| Cell therapy |
| 5.86 |
Quantro Therapeutics GmbH |
| Functional genetic and transcriptomic technologies |
| 38.79 |
Sernova Corp. | Diabetes | 4.77 | ||
TAG Therapeutics GmbH | Oncology | 20.16 | ||
Topas Therapeutics GmbH |
| Nanoparticle-based therapeutics |
| 23.86 |
Tubulis GmbH | Antibody Drug Conjugates | 8.10 | ||
Verto Therapeutics Inc. | Oncology | 5.64 |
Intellectual Property
We seek to protect and enhance the value of our proprietary drug discovery programs as well as our technology platforms, including proprietary processes, technologies, inventions, and methods, and their application to the R&D of treatments for serious diseases and methods of manufacture through the filling of intellectual property. We pursue a multi-layered intellectual property strategy to protect our technology platforms and their application to the R&D of treatments for serious diseases. One focus of our intellectual property strategy is to provide protection for our platforms and pipeline assets currently in development. We also pursue intellectual property protection for assets that may be used in future development programs and/or that may be of interest to our partners, or otherwise may prove valuable in the field.
Patent filings protect various aspects of our technology platforms and our pipeline assets, while other aspects remain trade secrets. We also pursue other methods of protection, including seeking trademark registrations, as appropriate. Many of our intellectual property assets were developed and are owned solely by us, some have been acquired and are solely owned by us, some have been developed via collaboration and are jointly owned, and some have been licensed from third parties. We will continue to make additional patent application filings and pursue opportunities to acquire and license additional intellectual property assets, technologies, platforms, or pipeline assets, as developments arise or are identified.
As of December 31, 2024, our owned patent portfolio included more than 45 patent families, each of which includes at least one filing in the United States or Europe, and several of which are pending or granted in multiple jurisdictions.
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Below, we provide a summary of the contours of our current intellectual property portfolio as it relates to different aspects of our business.
Government Regulation
Government authorities in the EU, the United States and other countries and jurisdictions extensively regulate, among other things, the research, development, testing, manufacture, quality control, approval, packaging, storage, record-keeping, labeling, advertising, promotion, distribution, marketing, post- approval monitoring and reporting and import and export of pharmaceutical products. Compliance with applicable statutes and regulations and other requirements of regulatory authorities requires the expenditure of substantial time and financial resources.
Regulation of Drugs and Biologics
Like all companies in our industry, we need to be in compliance with a large set of international regulations. In the EU, pharmaceutical products are subject to a comprehensive scheme of regulatory requirements mainly set out at EU level, but country-specific regulations at EU member state level remain essential in many respects. These regulations exercise oversight over all aspects of our operations including, but not limited to, research, development, testing, manufacturing, and quality control. They also govern all aspects of the operations of our customers and the partners with whom we co-own pipeline assets, including assessing safety and efficacy for purposes of marketing approval, labeling, storage, record keeping, commercialization, distribution, post-approval monitoring, advertising, pricing, and more.
In the United States, the FDA regulates pharmaceutical products. The Federal Food, Drug, and Cosmetic Act, the Public Health Service Act and other federal and state statutes and regulations apply to us, our customers, and our partners who develop our pipeline assets. Failure to comply with applicable U.S. requirements may subject a company to a variety of administrative or judicial sanctions, such as FDA refusal to approve pending new drug applications (“NDAs”) or biologics license applications (“BLAs”), warning or untitled letters, product recalls, product seizures, total or partial suspension of production or distribution, injunctions, fines, civil penalties, and criminal prosecution.
Preclinical Research
A robust package of preclinical data is required before clinical trials can begin. In the EU, if preclinical results warrant continuing development of the product candidate, before a clinical trial may commence, applicants are required to submit a clinical CTA to each country’s national health authority and an independent ethics committee. The CTA must include, among other things, a copy of the trial protocol and an investigational medicinal product dossier with supporting information, in particular preclinical data and information about the manufacture and quality of the medicinal product under investigation. In the United States, if preclinical results warrant continuing development of the product candidate the results of the studies are submitted to the FDA as part of an investigational new drug application, or IND. An IND includes, among other things, items such as preclinical data, manufacturing information, a proposed clinical protocol and an investigational plan and must be reviewed by the FDA and become effective before proposed clinical testing can begin.
Regulation of Testing Facilities
Our facilities are audited by regulatory agencies such as the FDA, MHRA, and similar foreign regulatory authorities as well as our customers to ensure compliance with requirements designed to ensure the quality and integrity of the testing process and data such as GLP and GMP and other requirements adopted by the EMA, the FDA, the Ministry of Health in the United Kingdom and by similar regulatory authorities in other countries, as applicable. GLPs and GMP require standardized procedures for all equipment, processes, and analytical tests, for recording and reporting data, and for retaining appropriate records.
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Clinical Trials, MAA, NDA or BLA Preparation and Submission
In the EU, all phases of clinical development are monitored and audited extensively by regulatory authorities of the relevant member states. Authorities scrutinize all clinical activities and data, and our partners must submit annual reports to the controlling authorities of the relevant member states detailing the progress of the trial. Our partners must also submit any information that suggests a significant risk to human patients or any clinically important increase in the rate of serious suspected adverse reactions to regulatory authorities as and when they discover such information. The United States has adopted a similar regulatory scheme to the EU. Our partners typically carry out clinical development of our pipeline, including the conduct of human trials and interaction with regulatory authorities.
Data Privacy and Security Laws and Regulations
As a primarily business-to-business focused organization, we do not market, sell, or distribute products or services directly to patients or consumers. Accordingly, the personal information that we collect and process, including human tissues and patient samples, is generally limited to what is necessary to conduct business with other businesses within our industry.
Nevertheless, we hold confidential personal information relating to persons who have been and/or still are employed by the company. The possession, retention, use and disclosure of such information are highly regulated, particularly in the European Economic Area (“EEA”). The GDPR controls how personal data must be handled and places significant restrictions on the export of personal data from within the EEA to other third countries that have not been found to provide adequate protection for such personal data, including the United States, and the efficacy and longevity of current transfer mechanisms between the EEA and the United States remain uncertain. In the United States, numerous federal and state laws and regulations, including data breach notification laws, health information privacy and security laws, including Health Insurance Portability and Accountability Act (“HIPAA”), and federal and state consumer protection laws and regulations (e.g., Section 5 of the Federal Trade Commission Act), that govern the collection, use, disclosure, and protection of health-related and other personal information could apply to our operations or the operations of our partners. Failure to comply with these laws, where applicable, can result in the imposition of significant civil and/or criminal penalties and private litigation. Privacy and security laws, regulations, and other obligations are constantly evolving, may conflict with each other to complicate compliance efforts, and can result in investigations, proceedings, or actions that lead to significant civil and/or criminal penalties and restrictions on data processing.
Other Environmental, Health and Safety Laws and Regulations
We may be subject to numerous environmental, health and safety laws and regulations, including those governing laboratory procedures and the handling, use, storage, treatment and disposal of hazardous materials and wastes. From time to time and in the future, our operations may involve the use of hazardous and flammable materials, including chemicals and biological materials, and may produce hazardous waste products. Even if we contract with third parties for the disposal of these materials and waste products, we cannot eliminate the risk of contamination or injury resulting from these materials. In the event of contamination or injury resulting from the use or disposal of our hazardous materials, we could be held liable for any resulting damages, and any liability could exceed our resources. We also could incur significant costs associated with civil or criminal fines and penalties for failure to comply with such laws and regulations.
We maintain liability insurance (including, where applicable, workers’ compensation) to cover us for costs and expenses we may incur due to injuries to our employees, but this insurance may not provide adequate coverage against potential liabilities. We also tailored several continuities plans for different locations to mitigate serious environmental issues.
In addition, we may incur substantial costs to comply with current or future environmental, health and safety laws and regulations.
Current or future environmental laws and regulations may impair our research, development, or production efforts. In addition, failure to comply with these laws and regulations may result in substantial fines, penalties, or other sanctions.
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Competition
The market for biotech/pharmaceutical R&D partnering, and services is competitive, based on modality-by-modality or technology-by-technology comparison. However, we believe we are well-positioned to offer our partners an integrated solution that cannot be replicated by combining selected elements made available by other service providers. We believe our services are differentiated based on the degree of integration, the number of modalities, precision, relevance, agility, and capacity to generate new data and the ability to exploit it with advance computing.
We believe that Evotec is one of very few companies that has assembled such a seamlessly integrated precision medicine platform.
We compete in an industry characterized by rapidly advancing technologies, intense competition, and a complex intellectual property landscape. With respect to other players in specific fields in the industry, we consider our competition to be as described below:
| ● | External drug discovery and development: Several large CROs including Wuxi Apptec and Charles River Laboratories. Large pharma’s incumbent R&D organizations. |
| ● | PanOmics and patient-relevant disease modeling: Recursion and Adaptive Biotechnologies, and, in the field of data-driven precision medicine in oncology, Schrödinger, Tempus. |
| ● | Tech enabled business models: Abcellera, Certara, Recursion and Schrödinger. |
| ● | iPSC-based regenerative therapy of Type I diabetes: Vertex Pharmaceuticals, Novo Nordisk, and Sana Biotechnology, all of whom are developing iPSC-based treatments for Type I diabetes. |
| ● | iPSC-based treatments of cancer and immune disorders: Fate Therapeutics and Century Therapeutics. |
| ● | Treatment of Parkinson’s disease and heart failure: BlueRock Therapeutics (acquired by Bayer in August 2019); |
| ● | iPSC-based assay developments: Fate Therapeutics, Allele Biotechnology, Takeda, and Fujifilm, along with Contract Manufacturing Organizations (“CMOs”) such as Lonza, SCM Lifescience, Reporcell and Charles River Laboratories. |
| ● | Biologics development and manufacturing: CDMOs such as Lonza, Samsung Biologics, Boehringer Ingelheim, Wuxi Biologics or Avid Bioservices. |
| ● | Co-developed assets: |
| C. | Organizational structure. |
Evotec SE is a publicly listed European stock corporation operating under German law. Our headquarters are in Hamburg, Germany. We have operating sites in Germany, Italy, France, UK and US. The group has been successful in creating both operational and technological synergies between the sites and geographical regions by way of organic growth and strategic acquisitions. A listing of our significant subsidiaries and their jurisdiction of incorporation is included in Exhibit 8.1 to this 20-F filing.
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| D. | Property, plants and equipment. |
Our headquarters are in Hamburg, Germany, where we occupy office and laboratory space. We manage further laboratories and office facilities in Göttingen, Munich and Cologne in Germany, Toulouse and Lyon in France, Abingdon and Manchester in the United Kingdom, Princeton, Framingham, Branford, Seattle, and Redmond in the United States, Verona, and Medolla in Italy. Manufacturing areas are available in Verona, Abingdon, Seattle, and Redmond sites. Some key steps to build this facilities setup were:
| ● | In July 2019, we acquired Just Biotherapeutics Ltd., located in Seattle, United Stated (Just – Evotec Biologics), including 3,580 square meters of laboratory and office space. |
| ● | In July 2020, we acquired the Biopark by Sanofi SAS in Toulouse from Sanofi, including all land and buildings of the former Sanofi site. We also took over a second site of Sanofi in Lyon. |
| ● | In the second quarter of 2021 we acquired the Verona site from GlaxoSmithKline SpA (“GSK”), consisting of 41,057 square meters of laboratory, production and office space. |
| ● | The acquisition of a dedicated site for R&D of gene therapy-based projects in Orth/Donau, Austria as part of its plan for profitable growth. The decision to close the site was announced in May 2024. |
| ● | In 2022, we added Proteomics capacity enlarging our footprint in Munich (new campus) and we expanded our laboratories in Princeton (U.S.), in Abingdon (UK) and in Verona (Italy). |
| ● | In the second half of 2022, we acquired Rigenerand in Medolla (now called Evotec (Modena) Srl) and an API production site in Halle (now called Evotec Drug Substance (“DS”)). In the first half of 2024 the group decided to discontinue the operation of Halle/Westphalia, Germany. On November 5, 2024, we have announced the sale of our chemical API manufacturing site, Evotec DS GmbH, located in Halle/Westphalia, to Monacum Partners GmbH - a Munich based Private Equity firm. |
| ● | In 2022, we completed the preparation activities to transfer our operations from the previous U.S. Watertown site to a new site located in Framingham (2,392 sqm). We moved into the new site at the beginning of 2023. |
| ● | In April 2024 we further consolidated our footprint through the closure of Marcy l’Étoile site in France |
| ● | In 2024 we optimized our footprint in Hamburg and in Göttingen through the consolidation of offices spaces and buildings. |
| ● | In 2024 we opened the new JPOD2 building in Toulouse adding 14.900sqm to our Biotherapeutics footprint. |
| ● | At the end of 2024 we entered in a new labs building in Alderley Park with the activation of building B22 |
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The following table summarizes information with respect to the principal facilities leased and owned1) by us at the end of 2024:
| Area | |
Location | SQM total (gross) | |
France Total: | 82,219 | |
Lyon | 2,270 | |
Toulouse1) | 79,949 | |
Germany Total: |
| 33,174 |
Cologne | 981 | |
Göttingen | 9,919 | |
Hamburg |
| 19,858 |
Munich |
| 2,416 |
Italy Total: | 42,489 | |
Verona1) | 41,150 | |
Medolla1) | 1,339 | |
UK Total: | 31,054 | |
Abingdon | 24,049 | |
Nether Alderley | 7,005 | |
US Total: |
| 24,994 |
Branford |
| 2,192 |
Princeton |
| 3,945 |
Redmond | 12,887 | |
Seattle | 3,578 | |
Framingham |
| 2,392 |
Evotec total | 213,930 |
We lease an aggregate of approximately 91,000 square meters, in Europe and the United States. Our leases expire on various dates from 2026 to 2043 (indicatively).
To facilitate the continued growth of our company, we regularly invest in upgrading and expanding our technology and infrastructure. For example, we have made major enhancements to our technology platform regarding the areas of translational biology, high-content imaging and proteomics. Additionally, we have made our scientific operations more efficient by adding additional state-of-the-art sample management technology.
We have completed construction of our first J.POD facility in North America, an integral part of the J.DESIGN platform of Just—Evotec Biologics. We expect this facility fulfill our production requirements for the coming years and strengthen our position as a major partner in drug discovery and development with pioneering technologies in the field of biologics. This new facility became operational in August 2021. In 2024, we completed the construction of our second J.POD facility in Toulouse. We also continue to further upgrade and digitize our administrative tools and systems. We will continue to make CapEx to secure the further growth and scalability of our company.
Environmental Issues
To the best of our knowledge, currently there are no foreign, federal, state or local environmental laws, rules or regulations that will materially affect our results of operations or our position with respect to our competitors. However, we can provide no assurance of the effect that any possible future environmental laws will have on our operating results.
Item 4A. Unresolved Staff Comments
No unresolved comments.
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Item 5. Operating and Financial Review and Prospects
| A. | Operating results. |
You should read the following discussion and analysis of our financial condition and results of operations together with our audited financial statements and related notes included elsewhere in this annual report. The following discussion is based on our financial information prepared in accordance with the IFRS, as issued by the International Accounting Standards Board, or IASB, and endorsed in the EU, which may differ in material respects from generally accepted accounting principles in other jurisdictions, including U.S. Generally accepted accounting principles (“GAAP”). The following discussion includes forward-looking statements that involve risks, uncertainties, and assumptions. Our actual results may differ materially from those anticipated in these forward-looking statements because of many factors, including but not limited to those described in “Risk Factors” and elsewhere in this prospectus. Please also see “Cautionary Note Regarding Forward-Looking Statements.”
For information regarding our consolidated results, segment results and liquidity and capital resources for the year ended December 31, 2023 as compared to the year ended December 31, 2022, refer to “Operating and Financial Review and Prospects” in our annual report for the year ended December 31, 2023, which information is incorporated by reference herein.
Overview
We generate revenue primarily through three core collaboration routes: (1) by providing our drug discovery and development capabilities on a fee-for-service and FTE-rate basis; (2) by receiving milestones and royalties on partnered assets; and (3) by creating value through equity ownership in emerging, highly innovative biotechnology companies and translational academic institutional projects. Contracts with our partners can include elements of one or more of our three core collaboration routes.
Until December 31, 2023, we reported the results of our operations in two operating segments: EVT Execute and EVT Innovate. EVT Execute included mainly fee-for-service and FTE-rate arrangements where our customers own the intellectual property, whereas EVT Innovate comprised of internal R&D activities as well as services and partnerships that originated from the R&D activities where we typically owned or co-owned intellectual property with our strategic partners or participated on the jointly developed intellectual property.
As of January 1, 2024, a new segment reporting was introduced and moved from the segments EVT Execute and EVT Innovate towards Shared R&D and Just – Evotec Biologics to better steer our business and to reflect the underlying trends, evolutions and activities of the various business areas we are involved in. We believe that the two new reportable segments Shared R&D and Just – Evotec Biologics represent fairly and provide a better information to external stakeholders on how resources are allocated and how we manage our overall performance. The evaluation of each reportable segment by the management is performed based on revenues and adjusted EBITDA.
For the year ended December 31, 2024, we reported €797.0 million in revenue, representing growth of 2.0% from the year ended December 31, 2023, and €196.1 million in net losses, representing an increase in net loss of €112.2 million compared to the year ended December 31, 2023. We also reported adjusted earnings before interest, taxes, depreciation, and amortization (“EBITDA”) of €22.6 million for the year ended December 31, 2024, representing a decrease of €43.8 million compared to the year ended December 31, 2023. Adjusted EBITDA is a measure that is not defined under IFRS. For further information about how we calculate Adjusted EBITDA, the limitations of its use and its reconciliations to comparable IFRS measures, see “–Key Performance Metrics and Non-IFRS Measures.”
Key Factors Affecting Our Results
Factors affecting our results of operations and financial condition include the factors described below.
Market Demand for External Innovation
Our financial results are impacted by our partners and customers’ needs for external innovation through collaborating or outsourcing their R&D initiatives and/or highly innovative manufacturing activities and our ability to meet those needs. We will sustain growth only if our existing partners and customers continue to rely on our expertise and capacity and if additional companies select us as their partner of choice for drug discovery and development.
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For the past few decades, the global pharmaceutical industry has been struggling with declining R&D efficiency in introducing new products to the market. As a result, pharmaceutical companies of all sizes have been and continue to be under pressure to re-evaluate and adjust their business strategies, in particular by accessing innovative technologies, such as AI and ML, and pursuing innovative treatment modalities, such as personalized medicine, cell therapy and gene therapy. New companies have been formed to specifically develop these technologies and modalities. Moreover, there is an increased focus on early prediction parameters to determine the success or failure of new drugs. To access innovation in a capital-efficient manner, industry players increasingly rely on external sources, such as our innovation hub, for innovative R&D and manufacturing expertise and capacity.
We believe that market demand for external innovation will continue to drive demand for our assets and services, facilitate additional collaboration opportunities and potentially improve the volume and terms of partnerships that we are able to secure. We believe this trend will increase the likelihood of strategic, integrated, long-term collaborations and drive our continued growth.
Efficiency and Scientific Excellence of our own R&D Activities
Our performance is dependent not only on the market’s need for external innovation, but also on our own ability to provide innovative solutions. For this reason, investing in technologies and platforms is a core part of our strategy. In 2024, we spent €50.9 million (2023: €68.5 million) in R&D, and we intend to continue to dedicate a significant number of financial resources to ensuring that our offerings continue to meet the industry’s needs, however more focused on selected R&D projects.
For example, we are allocating a significant number of resources to improving our PanOmics and PanHunter platform, our capabilities for AI-driven development of biologics and our iPSC platform. Investments in maintaining and expanding our technological leadership increases our short-term expenses while opening possibilities for future revenue growth and sustainability.
Scientific Results and Third-Party Decisions
An important pillar of our growth strategy is the generation of milestones and royalties. Our pipeline currently includes more than 140 partnered assets. We define our pipeline to include candidates that we wholly own and those for which we have the right to receive royalty or milestone payments. Pipeline assets with respect to which we have the right to receive royalty or milestone payments include those that we will have initially developed and subsequently licensed or assigned to partners for continued preclinical and clinical development as well as those that have been initially developed by our partners and that have become the subject of a joint research project. We do not count in our pipeline candidates being developed by partners in whom we have solely an equity stake and no right to milestone or royalty payments with respect to their candidates in development.
Our financial results depend, currently to a limited extent, on the success of our partners’ clinical development of the co-owned pipeline assets, receipt of regulatory approval and commercialization. A partner may choose to end the development of a specific program for scientific or commercial reasons, and we typically have no ability to influence such decisions, which may be driven by factors such as pipeline prioritization and the ability to obtain additional required capital. Our future financial results therefore depend, in part, on the judgment and financial health of our partners. We mitigate this risk through diversification in our portfolio.
Revenue Mix and Gross Margin
We generate revenue either from fee-for-service and/or FTE-rates-based contracts, by receiving milestones and royalties on assets or partnerships, or any combination thereof. Revenues can be further differentiated based on our technologies and platforms. Changes in the allocation of revenues between contract types and technologies mainly affect our cost of sales, gross profit, and gross margin.
Additionally, we have invested in our biologics manufacturing facilities (J.POD) which, once at full operational capacity, we expect to generate higher average gross margins than our existing business.
Acquisitions and Disposals
Strategic acquisitions are part of our strategy for growth and strengthening our competitive position. We continually evaluate the market for attractive opportunities that are accretive to our business. We typically acquire companies that expand our value chain through access to new technologies and/or additional capacity, extend our offering and value chain, provide access to new customers, or allow for the extension of our geographical reach.
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On November 5, 2024, we announced the divestment of our chemical API-focused CDMO operation in Halle/Westphalia (Evotec DS) to Monacum Partners GmbH, Munich, Germany. This transaction aligns with our strategic optimization efforts, concentrating resources on key growth drivers. The transaction was officially concluded on December 2, 2024.
In addition, we have acquired, and may continue to acquire minority stakes in early-stage development companies through our EVOequity program, which is described in further detail under Item 4 of this annual report. These companies can either be entities with no prior relationship, or spin-offs from our other programs, such as our BRIDGEs program. The related transactions may result in significant influence over the acquired entity in line with the IFRS definition presented in IAS 28 (generally 20% or more of voting rights) and therefore require us to account for these investments using the equity method. In this case, in addition to the balance sheet impact, our share of the investee’s profit or loss will affect our results of non-operating result under “share of the result of associates accounted for using the equity method,” but will have no effect on our Adjusted EBITDA.
Foreign Currency Exchange Rates
Due to our international business operations, we are subject to both foreign exchange transaction and translation risks. Our reporting currency is Euro; however, we also incur revenues and expenses in U.S. dollar and pound sterling. Other currencies are of less relevance.
Transactional risk arises when we and our subsidiaries execute transactions in a currency other than our respective functional currency. Our principal exposure to foreign exchange effects relates to the U.S. dollar and pound sterling. In 2024, 62% and 10% of our revenue and 31% and 18% of our cost of revenue was in U.S. dollars and pound sterling, respectively. In 2023, 65% and 11% of our revenue and 28% and 20% of our cost of revenue was in U.S. dollars and pound sterling, respectively.
Where we are unable to reconcile sales generated in a foreign currency with expenses incurred in the same currency, our operating results will be adversely affected by exchange rate fluctuations. We also use derivatives such as currency futures and swaps to minimize exchange risk.
R&D Tax Credits
We receive R&D tax credits for qualifying research related expenses mainly in France for the Toulouse and Lyon sites, UK and Italy. The credits are recognized under other operating income. These credits amounted to €46.9 million in 2024 as compared to €44.0 million in 2023.
Description of components of Results of Operations
Revenues
We generate revenue either from fee-for-service and/or FTE-rates-based contracts, by receiving milestones and license fees, or any combination thereof. Revenues can be further differentiated based on our technologies and platforms. Changes in the allocation of revenues between contract types and technologies mainly affect our cost of sales, gross profit, and gross margin.
Costs of Revenue
Costs of revenue include the cost of personnel directly associated with revenue-generating projects, facilities and overhead used to directly support those projects, and outsourced services used as well as materials consumed in the provision of the products or services as well as amortization and depreciation.
R&D Expenses
Our R&D expenses comprise expenses incurred in connection with our in-house discovery platforms and developing new unpartnered pipeline assets as well as overhead expenses for both our partnered and unpartnered R&D projects.
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We expense our pharmaceutical research activities as incurred. Due to the high uncertainty associated with early-stage development activities in the pharmaceutical sector, the precondition for the capitalization of development expenses related to work on pharmaceutical products as outlined in International Accounting Standards (“IAS”) 38 is generally not satisfied. Therefore, we have not capitalized internally generated pharmaceutical development costs to date. However, a significant portion of our R&D expenditure is focused on our platforms and technology, in which the preconditions of IAS 38 can be satisfied. Evotec capitalized € 2.4 m of R&D expenses in 2024 related to development activities of our platforms and underlying technology.
R&D projects that are acquired in a business combination are capitalized at fair value when those R&D projects are expected to generate probable future economic benefits to our business. R&D costs acquired in a business combination are not amortized until they are sustainably generating benefits.
We expect to invest a significant amount into R&D expenses in the coming years, however, the investments will represent a balance between strong investments in Evotec’s capabilities to improve efficiency and precision medicine platforms, and financial stewardship in a challenging macroeconomic environment. Partnered R&D expenses ended in 2023 with the completion of the previous Sanofi agreement, thus R&D Expense is synonymous with ‘Unpartnered R&D Expense’ in 2024.
Selling, General and Administrative Expenses
Our selling expenses mainly consist of personnel costs (including share-based compensation), social security, travel costs and consultancy expenses of our business development team. General and administrative expenses primarily consist of personnel-related costs (including share-based compensation) for procurement and logistics, finance, legal, human resources, information technology, investor relations, risk management and other administrative functions, professional fees, accounting and legal services, insurance and facility costs related to space used by the support functions. These costs relate to the day-to-day administrative operation of the business and are unrelated to the R&D of any individual asset.
Impairment of Intangible Assets and Goodwill
Impairment of intangible assets and impairment of goodwill consists of the losses resulting from the differences between the carrying amount of related assets and their recoverable amount, which is the higher of the asset’s fair value less cost to sell or value in use. An impairment of goodwill may occur in case the expected performance of the underlying cash-generating unit falls below the expectation at the time of the acquisition of the relevant business. Impairments of intangible assets typically occur when scientific programs do not meet expectations in terms of scientific results or timelines for partnering, thereby impacting expectations for future cash flows.
Other Operating Income
Other operating income mainly consists of tax credits received from tax incentive programs in the context of qualifying R&D expenses in different jurisdictions and refunds from third parties for cost charges.
Tax credits can regularly be offset partially or fully from tax payments to fiscal authorities. We account for income from such R&D tax credit programs as other operating income instead of offsetting them from income tax expenses.
In addition, we recharged current costs incurred at the ID Lyon sites to Sanofi in connection to our agreements signed in 2018, which ended in 2023. Sanofi agreed to license to us most of its infectious disease research and early-stage development portfolio and transfer its operational infectious disease research unit to us, in addition to providing significant mid-term funding to ensure support and progression of the portfolio for which it retained certain option rights on the development, manufacturing, and commercialization of anti-infective products. We recognize these amounts in other operating income when they are a direct reimbursement of costs. There is no underlying direct exchange of these services for this income and therefore a recognition as revenue is not suitable. The related expenses are recognized under R&D expenses.
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Other Operating Expenses
For 2023 and 2024, the largest contributor to other operating expenses were the internal and external costs associated with recovery from the cyber-attack which occurred in the second quarter of 2023. In prior years, Other operating expenses mainly included expenses that we recharge to our partners for specific projects, for example related to expenses for the ID Lyon agreement, which ended in 2023. These expenses include facility costs, consultancy expenses, personnel costs, and incidental wage costs; outsourced services, materials consumed and depreciation. The related income is recognized under other operating income.
Reorganization Costs
Reorganization costs consists of all direct and incremental costs arising from a formal restructuring program, in accordance with IAS 37. Types of costs included are employee termination benefits, contract termination costs, consulting and legal fees directly associated with the program, as well as onerous contract obligations that arise from the program.
Interest Income and Expenses
Interest income consists of interest accrued or paid on cash deposits and short-term investments as well as other financial instruments.
Interest expenses consist primarily of interest from our Euro denominated short-term and long-terms loans and promissory notes. A portion of our finance expenses are related to interest expense on our revolving credits, which we utilize at certain points in the year as needed. Interest expenses also arise from interest rate swaps, from our lease obligations according to IFRS 16 and for the unwind of discounts of our earn-out liabilities.
Measurement result from Investments
Our measurement result from investments includes fair value adjustments for investments measured in accordance with IFRS 9.
Share of the Result of Associates Accounted for Using the Equity Method
Share of the result of associates accounted for using the equity method consists of our participation in the profits or losses generated as well as fair value differences, where applicable.
Foreign Currency Exchange Gain (Loss), Net
Our business and reported profitability are affected by fluctuations in foreign exchange rates mainly between the U.S. dollar, pound sterling and the Euro. A strengthening/weakening of these currencies as compared to each other and against other currencies, leads to foreign currency exchange gains or losses in our consolidated income statement.
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Tax Income (Expense)
Tax income (expense) represents the tax charge or credit on our profit or loss for the year and includes both current and deferred taxation. Tax income (expense) is recognized in the income statement unless it relates to items recognized directly in equity when it is recognized through the statement of comprehensive income. Deferred tax income (expense) consists of the tax impact of tax loss carryforwards and temporary differences. In the future, we expect to continue to benefit from certain tax loss carryforwards as we have incurred negative income in certain group entities including Evotec SE in the past, which is discussed in more detail under “Result of Operations—Income and deferred taxes” below. We expect our income taxes to continue to increase on an absolute Euro basis as we continue to grow.
Result of Operations
The following table summarizes our consolidated statements of operations for each period presented:
Years Ended December 31, | |||||||||
2024 | 2023 | 2022 | |||||||
(In € thousands) |
|
|
|
|
|
| |||
Revenues | 796,967 | 781,426 | 751,448 | ||||||
Costs of revenue |
| (682,086) |
| (606,375) |
| (577,383) | |||
Gross profit |
| 114,881 |
| 175,051 |
| 174,065 | |||
R&D expenses |
| (50,857) |
| (68,529) |
| (76,642) | |||
Selling, general and administrative expenses |
| (188,201) |
| (169,610) |
| (156,190) | |||
Other operating income |
| 52,700 |
| 64,793 |
| 81,582 | |||
Other operating expenses |
| (16,116) |
| (44,202) |
| (1,965) | |||
Impairments |
| — |
| (5,011) |
| — | |||
Reorganization costs | (54,930) | — | — | ||||||
Operating income (loss) |
| (142,522) |
| (47,507) |
| 20,850 | |||
Gain (loss) on investment in equity instruments reevaluation |
| (38,513) |
| (9,143) |
| (172,159) | |||
Share of profit (loss) of associates and Joint ventures |
| (4,312) |
| (20,752) |
| (15,098) | |||
Financial income |
| 2,435 |
| 9,263 |
| 8,336 | |||
Financial expense |
| (11,699) |
| (11,739) |
| (13,150) | |||
Other non-operating income (expense) |
| 636 |
| (714) |
| 12,357 | |||
Gain from bargain purchase |
| — |
| — |
| 4,908 | |||
Net Income (loss) before taxes | (193,977) | (80,593) | (153,956) | ||||||
Income taxes |
| (2,102) |
| (3,320) |
| (21,698) | |||
Net income (loss) |
| (196,078) |
| (83,913) |
| (175,655) | |||
Revenues
Revenues increased by €15.5 million, or 2.0%, to €797.0 million in 2024 from €781.4 million in 2023. The growth was mainly driven by the overall revenue growth within Just – Evotec Biologics. Revenues from milestones decreased to €2.9 million in 2024 from €4.8 million in 2023.
Revenues from fee-for-service and FTE-rate-based research services increased by €10.5 million or 1%, to €737.4 million in 2024 from €726.9 million in 2023.
Total revenues in the Shared R&D segment decreased by €61.6 million, or 9%, to €611.4 million in 2024 from €673.0 million in 2023. The overall challenging market conditions in 2024, specifically within the Biotech sector, contributed strongly to the reduced revenues. The impact was felt most drastically within our more standalone and fast-turning offerings within our Discovery business. Revenues within Just – Evotec Biologics increased by €77.1 million, or 71%, to €185.6 million in 2024 (2023: €108.4 million). This growth was driven by further progression of the Sandoz partnership, other new deals, and expansions of existing relationships.
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Costs of Revenue
Costs of revenue increased by €75.7 million, or 12.5%, to €682.1 million in 2024 from €606.4 million in 2023, which led to a group gross margin of 14.4% in 2024, compared with 22.4% in 2023.
The increase in cost of revenues was mainly attributable to the accelerated expenses for Just – Evotec Biologics, which increased by €59.4 million year over year to €173.1 million in 2024 compared to €113.7 million in 2023. This was primarily driven by an increase in headcount to fulfill the increased sales demand and continue building up the J.POD facility in the Toulouse. The gross margin increased to 7.3% in 2024 from (4.8)% in 2023.
Within Shared R&D, costs of revenues increased by €16.7 million year over year. This was driven by higher labor costs due to the yearly merit increase and inflation, partially offset by the first positive impacts of the reorganization program. Gross margin decreased overall to 16.7% in 2024 from 26.8% in 2023.
R&D Expenses
In 2024, Evotec continued to progress its projects e.g., in central nervous system disorders, diabetes, immunological diseases, infectious diseases, inflammation, kidney diseases, metabolic diseases, oncological diseases, and rare diseases together with our partners. Our R&D strategy is built on leveraging proprietary platforms to enable upside-bearing strategic deals, as demonstrated in four different exclusive collaborations in kidney disease that are based on our proprietary PanOmics platform. Access to our platforms is provided in return for success based revenue components such as milestones payments and royalties. Hence, our R&D expenses have translated into a long-term pipeline of assets over time, which is described in more detail in the Business Overview.
As of 2024, R&D expenses were entirely self-funded, while in 2023 a residual amount of about 5% was related to R&D projects funded by Sanofi and classified as so called “partnered R&D”. The related activities focused on programs targeting infectious diseases, which were acquired in 2018 as part of the acquisition of Sanofi’s anti-infective unit in Lyon, the costs of which were assumed by Sanofi up to a certain amount. This contract ended November 2023 after over five years. Subsequent to the contract end, all capacities of the relevant units have been switched to the fee-for-service business available for Evotec’s partners.
R&D expenses decreased by €17.7 million, or 25.8%, to €50.9 million in 2024 from €68.5 million in 2023, The decrease in R&D expenses represents a balance between strong investments in Evotec’s capabilities to improve efficiency and precision medicine platforms, and financial stewardship in a challenging macroeconomic environment. Partnered R&D expenses ended in 2023 with the completion of the previous Sanofi agreement, thus R&D Expense is synonymous with ‘Unpartnered R&D Expense’ in 2024.
Selling, General and Administrative Expenses
Selling, general and administrative expenses (“SG&A”) increased by €18.6 million, or 11.0%, to €188.2 million in 2024 to €169.6 million in 2023, mainly driven by growth in employee headcount in most areas of the enabling functions. Personnel-related expenses increased by €7.9 million, to €105.3 million in 2024 compared to €97.4 million in 2023, mainly driven by growth in employee headcount in most areas of the enabling functions throughout the year, before returning to 2023 levels as a result of the reorganization. Consultancy costs decreased by €4.9 million, to €26.8 million in 2024 vs. €21.9 million 2023, as the company focused on cost reduction of external services. Insurance costs remained rather stable at €8.1 million. Audit and Tax expenses decreased by €0.2 million to €8.9 million in 2024 from €9.1 million in 2023. Furthermore, IT and license costs increased by €1.2 million to €15.0 million in 2024 from €13.8 million in 2023, due to continued expansion of IT capabilities.
Impairment of Intangible Assets and Goodwill
In 2024, there was no impairment of intangible assets recognized, compared to 2023, where we recognized an impairment of intangible assets of €5.0 million, which was linked to an impairment of an intangible asset within developed technologies. The impairment losses in 2023 were allocated mainly to Just – Evotec Biologics.
There were no impairment losses from goodwill in either 2024 or 2023.
41
Other Operating Income
Other operating income, which primarily includes non-IFRS 15 income and income from R&D tax credits, was €52.7 million in 2024 compared to income of €64.8 million for 2023. In 2023, the other operating income still included Sanofi recharges for Evotec ID Lyon (2023: €16.6 million), the contractual term with Sanofi ended in 2023. R&D tax credits were mainly recognized in France for the Toulouse and Lyon sites, UK, and Italy, resulting in overall R&D tax credit related other operating income of €46.9 million (2023: €44.0 million).
Other Operating Expenses
Other operating expense amounted to €16.1 million in 2024 (2023: €44.2 million). The significant decrease in 2024 was driven by the reduction of cyber-attack related costs from €43.5 million 2023, which comprises of €26.5 million internal costs and €15.9 million of external costs, to €8.6 million, which includes only external costs. Internal costs represent employee’s active efforts to restore normal operations after the attack. External costs are additional third-party costs incurred due to the cyber-attack, such as increased consulting and IT costs, that the Group would not have otherwise incurred. The external costs are considered to be an item that in magnitude, nature or occurrence would distort the presentation of the financial performance of the Group, as these are not deemed to be recurring costs.
Reorganization Costs
In 2024 Evotec faced significant organizational changes and a challenging market environment. During the year the management announced a priority reset, a restructuring program with significant impacts ranging from headcounts reduction to the optimization of the Group’s overall real estate footprint (either leased or owned) and to the sale and discontinuation of certain business lines.
The direct expenditures arising from the program (necessarily entailed by the restructuring and not associated with the ongoing activities) amount €54.9 million and include, employee costs, footprint optimization initiatives, cost to sell Evotec DS GmbH, and other direct costs. The program was still ongoing as of year-end, and is expected to generate € 40 million of annually recurring savings.
Interest Income
Interest income decreased by €6.8 million, or 73.7%, to €2.4 million in 2024 from €9.3 million in 2023 primarily due to lower volume of investing activities, directly correlating to lower interest income.
Interest Expense
Interest expense remained constant at €11.7 million in 2024 and €11.7 million in 2023.
Measurement result from Investments
Measurement result from investments decreased by €29.4 million, to € (38.5) million in 2024 from € (9.1) million in 2023, driven by the revaluation of our Recursion Pharmaceuticals, Inc (formerly Exscientia Ltd.) shares of € (12.0) million prior to disposal, and further fair value adjustments to our holdings in Blacksmith Medicines Inc. € (9.9) million, and Immunitas Therapeutics Inc. € (5.5) million.
Share of the Result of Associates Accounted for using the Equity Method and Impairment of Financial Assets
Share of the loss and impairment in connection with associates accounted for using the equity method decreased by €16.4 million, or 79%, to € (4.3) million in 2024 from € (20.8) million in 2023, reducing net result in both years.
Foreign Currency Exchange Gain (Loss), net
Foreign exchange gain amounted to €4.4 million (2023: € (2.5) million), mostly due to the weakened EUR vs USD from 1.1050 as per December 31, 2023 to 1.0389 as per December 31, 2024 which resulted in a revaluation in particular of the USD denominated cash and receivables after conversion in EUR.
42
Current tax expense and Deferred Taxes
Total tax income (expense) amounted to € (2.1) million for full year 2024, versus € (3.3) million in 2023. Thereof, Evotec recorded total income taxes of € (7.4) million (2023: € (7.0) million). The increase in the current tax expense is generally a result of an increase of the IFRIC provision exceeding the impact of decreased taxable profits in Evotec International GmbH and Evotec (France) SAS. Deferred tax income (expense) amounted to € 5.3 million (2023: € 3.7 million), generally relating to tax loss carryforward attributes as well as various other temporary differences.
We recognize deferred tax assets to the extent that it is probable that future taxable income will be available against which the deductible temporary differences, unused carry forward tax losses and unused tax credits can be utilized. This judgment is made annually and based on budgets and business plans.
Operating Results by Segments
The following tables detail our segment Revenues and Operating income for the years ended December 31, 2024, 2023 and 2022 for each segment:
Year ended December 31, 2024 | ||||||||
|
| Just-Evotec |
| Intersegment |
| |||
(In € thousands) | Shared R&D | Biologics | elimination | Evotec Group | ||||
Revenues |
| 611,394 |
| 185,573 |
| — |
| 796,967 |
Operating income (loss) |
| (126,170) |
| (16,353) |
| — |
| (142,522) |
Year ended December 31, 2023 | ||||||||
|
| Just-Evotec |
| Intersegment |
| |||
(In € thousands) | Shared R&D | Biologics | elimination | Evotec Group | ||||
Revenues |
| 672,977 |
| 108,449 |
| — |
| 781,426 |
Operating income (loss) |
| (8,122) |
| (39,385) |
| — |
| (47,508) |
Year ended December 31, 2022 | ||||||||
| Just-Evotec |
| Intersegment |
| ||||
(In € thousands) |
| Shared R&D | Biologics | elimination | Evotec Group | |||
Revenues |
| 702,020 |
| 49,428 |
| — |
| 751,448 |
Operating income (loss) |
| 83,887 |
| (63,037) |
| — |
| 20,850 |
For a segment revenue analysis see “—Revenues.”
Segment operating loss within Shared R&D increased by €118.0 million, to €(126.2) million for the year ended December 31, 2024, from €(8.1) million for the year ended December 31, 2023. Gross profit amounted to €102.2 million in 2024 from €180.3 million in 2023 and decreased therefore by 43% to previous year. The business growth was impacted by decrease in market demand. Selling, and general administrative expenses amounted to €158.9 million and increased by €15.7 million primarily due to higher personnel expenses and increased IT costs. R&D expenses decreased to €51.1 million in 2024 from €68.5 million in 2023. In addition, other operating income decreased by €12.7 million driven by the termination of the Sanofi agreement and other operating expenses decreased by €25.4 million, where the expenses incurred as part of the recovery efforts from the cyber-attack have significantly reduced in 2024.
Segment operating loss within Just – Evotec Biologics decreased by €23.0 million, to €(16.4) million for the year ended December 31, 2024, from €(39.4) million for the year ended December 31, 2023, primarily because of a €18.8 million increase in gross profit driven by higher revenues and a comparably lower increase of Costs of revenue, despite significant expenditure related to the ramp up of the JPOD2 facility in Toulouse. Selling, general and administrative expenses increased by €2.8 million, mainly due to higher personnel-related expenses tied to the build out of JPOD2. Other operating income and expenses (net) increased by €3.3 million primarily driven by lower expenses related to the cyber-attack than in 2023.
43
The following table provides the reconciliation of segment Operating income (loss) to Segment Adjusted EBITDA for the periods presented below:
Year ended December 31, 2024 |
| Year ended December 31, 2023 |
| Year ended December 31, 2022 | ||||||||
Shared | Just-Evotec | Shared | Just-Evotec | Shared | Just-Evotec | |||||||
(In € thousands) |
| R&D |
| Biologics |
| R&D |
| Biologics |
| R&D |
| Biologics |
Operating income (loss) |
| (126,170) |
| (16,353) |
| (8,122) |
| (39,385) |
| 83,887 |
| (63,037) |
Depreciation of tangible assets |
| 70,753 |
| 24,404 |
| 64,349 |
| 21,685 |
| 48,488 |
| 24,189 |
Amortization of intangible assets |
| 6,484 |
| — |
| 6,946 |
| — |
| 8,982 |
| — |
EBITDA |
| (48,933) |
| 8,051 |
| 63,173 |
| (17,700) |
| 141,357 |
| (38,848) |
Impairment of intangible assets |
| — |
| — |
| (108) |
| 5,119 |
| — |
| — |
Impairment of goodwill |
| — |
| — |
| — |
| — |
| — |
| — |
Change in contingent consideration (earn-out) |
| (158) |
| — |
| — |
| — |
| (79) |
| (776) |
Reorganization costs | 54,179 | 751 | — | — | — | — | ||||||
Cyber-related costs | 7,608 | 1,067 | 15,379 | 489 | — | — | ||||||
Segment Adjusted EBITDA (1) |
| 12,696 |
| 9,869 |
| 78,444 |
| (12,092) |
| 141,278 |
| (39,624) |
The following tables detail our Segment Adjusted EBITDA for the years ended December 31, 2024, 2023,and 2022 for each segment:
Year ended December 31, 2024 | ||||||
(In € thousands) |
| Shared R&D |
| Just-Evotec Biologics |
| Evotec Group |
Segment Adjusted EBITDA (1) |
| 12,695 | 9,868 | 22,564 | ||
| Year ended December 31, 2023 | |||||
(In € thousands) |
| Shared R&D |
| Just-Evotec Biologics |
| Evotec Group |
Segment Adjusted EBITDA (1) |
| 78,444 | (12,092) | 66,352 | ||
Year ended December 31, 2022 | ||||||
(In € thousands) |
| Shared R&D |
| Just-Evotec Biologics |
| Evotec Group |
Segment Adjusted EBITDA (1) |
| 141,278 | (39,624) | 101,654 | ||
| (1) | Segment Adjusted EBITDA is a non-GAAP measure and is defined as segment operating income adjusted for depreciation and amortization of intangibles, impairments on goodwill and other intangible and tangible assets and change in contingent consideration (earn-out), as well as other items that in magnitude, nature or occurrence would distort the presentation of the financial performance of Evotec. For a reconciliation of Adjusted EBITDA to net income (loss) on a group level see “—Key Performance Metrics and Non-IFRS Measures—Adjusted EBITDA. Segment Adjusted EBITDA is reconciled to segment operating income because certain items, including taxes and interest, are only accounted for on a group-wide basis and cannot be tracked on a segment basis. Segment operating income/(loss) is the most directly comparable financial measure calculated and presented in accordance with IFRS-IASB. |
Segment Adjusted EBITDA in the Shared R&D segment decreased by €65.7 million, or 84%, to €12.7 million in 2024 from €78.4 million in 2023, primarily driven by lower revenues on a rather stable cost base.
Segment Adjusted EBITDA in Just – Evotec Biologics increased by €22.0 million to €9.9 million in 2024 compared to a loss of €(12.1) million in 2023 driven by increased revenues and a comparably lower increase of costs.
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Key Performance Metrics and Non-IFRS Measures
We review several key performance metrics and non-IFRS measures to assess the progress of our business, make decisions about where to allocate time and investments and assess the near-term and longer-term performance of our business. The measures set forth below should be considered in addition to, not as a substitute for or in isolation from, our financial results prepared in accordance with IFRS. The following table sets forth these metrics as of and for the periods presented:
| Years Ended December 31, |
| ||||||||
2024 | 2023 | 2022 |
| |||||||
(In thousands, except number of customers, number of customers > €1 million revenue, repeat business) |
| |||||||||
Revenues | 796,967 | 781,426 | 751,448 | |||||||
Unpartnered R&D expenses | (50,829) | (64,818) | (70,204) | |||||||
Net income (loss) | (196,078) | (83,913) | (175,655) | |||||||
Adjusted EBITDA | 22,564 | 66,352 | 101,654 | |||||||
Number of customers | 849 | 838 | 819 | |||||||
Number of customers > €1 million revenue |
| 109 |
| 102 |
| 118 | ||||
Annual repeat business |
| 94 | % |
| 93 | % |
| 92 | % | |
Revenues
Revenue is generated through each of Evotec’s collaboration arrangements dependable on the nature of contract with Evotec’s customers, the (co-)ownership of the intellectual property and the stage of the project. Revenues are recognized from partners owning the IP and includes mainly fee-for-service and FTE-rate based arrangements. In addition to FTE-based revenues other revenues are generated from milestones, royalties and material recharges. Our revenues were €797.0 million and €781.4 million in 2024 and 2023, respectively. Thereof, €14.4 million and €9.4 million in 2024 and 2023 are related to private grants.
Unpartnered R&D Expenses
Evotec’s unpartnered R&D expenses comprise expenses incurred in connection with its in-house discovery platforms and developing new unpartnered pipeline assets as well as overhead expenses. From 2024 onwards, all R&D expenses are considered “unpartnered”.
Our unpartnered R&D expenses were €50.9 million and €64.8 million in 2024 and 2023, respectively.
Net Income (Loss)
Our net result decreased by €112.2 million, or 133.7%, to €(196.1) million in 2024 from €(83.9) million in 2023 mainly driven by a reduction in gross profit and reorganization costs.
Adjusted EBITDA
Adjusted Group EBITDA is defined as net income (loss) adjusted for interest, taxes, depreciation and amortization of intangibles, impairments on goodwill and other intangible and tangible assets, total non-operating results, change in contingent consideration (earn-out) and items that in magnitude, nature or occurrence would distort the presentation of the financial performance of the Group.
Adjusted EBITDA is a non-IFRS measure presented as a supplemental measure of our performance. Adjusted EBITDA should not be considered as an alternative to net income as a measure of financial performance. Adjusted EBITDA is presented because it is a key metric used by our Management Board to assess our financial performance. Management believes Adjusted EBITDA is an appropriate measure of operating performance because it eliminates the impact of expenses that do not relate directly to the performance of the underlying business. Our definition of this non-IFRS financial measure may not be comparable to similarly titled measures of other companies, thereby, reducing the usefulness of our Adjusted EBITDA as a tool for comparison.
45
Adjusted EBITDA decreased by €43.8 million, or 66%, to €22.6 million in 2024 from €66.4 million in 2023. Revenue increased year over year by €15.5 million, which was driven by an increase in Just – Evotec Biologics of €77.1 million, however we faced a revenue reduction in Shared R&D of €61.6 million due to the challenging market environment. Costs of revenues increased by €75.7 million or 12% mainly driven by an increase in Just – Evotec Biologics driven by higher revenues and additional costs for our JPOD2 operations in Toulouse, France. Gross profit decreased by €60.2 million from 2024 to 2023 and led to a gross margin of 14.4% in 2024 compared to 22.4% in 2023.
R&D expenses positively affected adjusted EBITDA as it decreased from 2024 compared to 2023 by €17.7 million. SG&A expenses increased by €18.6 million, or 11%, to €188.2 million in 2024 from €169.6 million in 2023 was mainly driven by higher personnel expenses. The reduction in other operating income of €12.1 million was mainly driven by the end of the Sanofi subsidies in 2023 also negatively impacted the Adjusted EBITDA.
The following table provides the reconciliation of net income (loss) to Adjusted EBITDA for the periods presented below:
| Years Ended December 31, | |||||
(In € thousands) | 2024 | 2023 | 2022 | |||
Net income (loss) |
| (196,078) |
| (83,913) |
| (175,655) |
Interest expense (net) |
| 9,264 |
| 2,476 |
| 4,814 |
Tax expense |
| 2,102 |
| 3,320 |
| 21,698 |
Depreciation of intangible assets |
| 95,157 |
| 86,034 |
| 72,677 |
Amortization of intangible assets |
| 6,484 |
| 6,946 |
| 8,982 |
EBITDA |
| (83,072) |
| 14,863 |
| (67,484) |
Impairment of intangible assets |
| — |
| 5,011 |
| — |
Impairment of goodwill |
| — |
| — |
| — |
Measurement result from investment |
| 38,513 |
| 9,143 |
| 172,159 |
Share of loss of associates accounted for using the equity method |
| 4,312 |
| 20,752 |
| 15,098 |
Other income from financial assets, net | — |
| — |
| — | |
Gain from bargain purchase |
| — | — | (4,908) | ||
Foreign currency exchange loss (gain), net |
| (4,369) |
| 2,523 |
| (13,083) |
Other non-operating income, net |
| 3,733 |
| (1,809) |
| 727 |
Change in contingent consideration (earn-out) |
| (158) |
| — |
| (855) |
Cyber-related costs | 8,674 | 15,869 | — | |||
Reorganization costs | 54,930 | — | — | |||
Adjusted EBITDA |
| 22,564 |
| 66,352 |
| 101,654 |
Number of Customers
Our number of customers increased to 849 in 2024 from 838 in 2023. An entity with multiple subsidiaries, segments, or divisions is defined and counted as a single customer, even if we have separate agreements with multiple subsidiaries, segments, or divisions that are part of the same entity.
Number of Customers Who Contributed More Than €1 million to Our Revenue
The number of customers who contributed more than €1 million to our revenue was 109 and 102 in 2024 and 2023, respectively.
Evotec’s largest three customers by revenue collectively accounted for 38% of revenues from contracts with customers in 2024. In 2023, Evotec’s three largest customers by revenue contributed 35% to our revenues. Other than BMS and Sandoz, no single customer contributed more than 10% of group revenues.
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Repeat Business
We define annual repeat business as the percentage of revenues with customers who have purchased products and services from us at least once in both the current year and the previous year. We review repeat business on a yearly basis. Repeat business was 94% and 93% in 2024 and 2023, respectively. We believe our significant amount of repeat business is primarily due to our ability to achieve success and high satisfaction of our partners and customers. The extent to which we generate repeat business from our customers will be an important factor in our continued revenue growth.
| B. | Liquidity and capital resources. |
We have historically funded our operations primarily through cash received in the ongoing operation of our business, from equity financing through private placements, and from the issuance of promissory notes or of bank debt. As of December 31, 2024, the company had available, yet undrawn credit lines in the amount of €75.1 million. Cash and cash equivalents are invested in accordance with our investment policy, primarily with a view to maintaining principal flexibility, liquidity, and capital preservation, and consist primarily of cash in banks and on hand, fixed deposits, and short-term deposits with an original maturity of three months or less. As of December 31, 2024, we had cash and cash equivalents of €306.4 million and short-term investments (corporate bonds and time deposits with maturities of less than three months) of €90.4 million. As of December 31, 2024, 57% of our cash, cash equivalents and investments were held in Germany, of which 73% and 27% were in Euros and U.S. dollars, respectively. 43% of our cash, cash equivalents and investments were held outside of Germany, of which 54% was held in France and Italy, mainly in Euros and U.S. dollars, 31% was held in the United Kingdom mainly in pound sterling and U.S. dollars, 14% in the United States, mainly in U.S. dollars.
In October 2021, we signed a finance loan with the Banque publique d’investissement (“Bpifrance”) with a line of credit amounting to €43.3 million to support the J.POD EU construction. The loan has a fixed interest rate of 0.55%. The total amount will be provided in various tranches from 2021 to 2025. Until December 31, 2024, €16.3 million remained undrawn. This loan is unsecured, and we are not subject to any covenants. The repayment is settled quarterly beginning in 2025. €33.2 million (77%) out of the total loan amount (€43.3 million) can be converted into a forgivable loan. An amount of €20.8 million has been subsequently reclassified from Non-Current Liability to Deferred Income in June 2024 as we determined that conditions were substantially met for forgiveness.
The promissory notes issued in June 2019 aggregated to a principal amount of €250.0 million. The promissory notes have fixed and variable interest rates and have three, five, seven, and 10-year maturities. The three-year tranches of €35.0 million was repaid as scheduled in June 2022 and the five-year tranches of €108.5 million have been repaid upon maturity in June 2024. The outstanding amount of promissory notes as per December 31, 2024 amounts to €106.5 million.
In July 2024, the Company secured a €250.0 million senior secured RCF to strengthen its liquidity position, supporting investments, working capital needs, and future growth. The RCF was intended as a backup credit line rather than a critical financing instrument. In the third quarter of 2024, we revised our financial performance guidance for the year, which created unexpected pressure on our debt covenants, including the net debt leverage covenant associated with the newly signed RCF. Draw stop and covenant waiver remain in place until us and our lenders renegotiate the RCF terms, reflecting the updated credit situation, in the second half of 2025. The liquidity risk resulting from the draw stop is limited, as we maintain sufficient operational liquidity to cover our funding needs for the year 2025.
European Investment Bank Loans
In 2017, we signed a financing agreement with a line of credit amounting up to €75 million with the European Investment Bank (EIB). Under the agreement, the total amount was provided in various tranches from 2017 until 2020. The final tranche was drawn in September 2020. Each tranche carries a fixed interest rate of 1.6%. Such interest is due and payable semi-annual or where a tranche is canceled or prepaid. The maturity date for each tranche is seven years from the respective disbursement date of the relevant tranche. The financing agreement includes a success share, which is paid as a percentage of future proceeds from the R&D projects for the years 2024 to 2030 and equity investments if these succeed for the period until 2030.
In December 2022, we signed a second financing agreement with the European Investment Bank. This line of credit amounts up to €150 million. Under this agreement, the total amount will be provided in various tranches from 2023 until 2025. Each tranche carries a fixed interest rate of 0.8%. Such interest is due and payable semi-annually or where a tranche is canceled or prepaid. The maturity date for each tranche is seven years from the respective disbursement date of the relevant tranche. As of December 31, 2024, we have drawn two tranches with a total value of € 93.3 million under this new loan facility. The financing agreement also includes a success share, which is paid as a percentage of future proceeds from the R&D projects for the years 2028 to 2037 and equity investments if these succeed until 2037.
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R&D Innovation Financing
Our R&D innovation financing loans entered into in 2019 and 2021 with a nominal amount of €29.0 million bear interests at a weighted average fixed interest rate of 1.36%. Final maturity of all four tranches is ranging from 2025 to 2031. The R&D innovation financing relates to individual R&D projects that were financed by IKB Deutsche Industriebank AG through Kreditanstalt für Wiederaufbau (“KfW”). All four tranches are amortizing with quarterly installments. As of December 31, 2024, the outstanding amount was € 20.5 million.
Evotec maintains the following three unsecured research loans with total commitment of €4.0 million at the end of 2024.
| ● | €0.5 million loan from Sanfelice 1893 Banco Popolare with a variable interest rate of 4.5% and final maturity in May 2027. Amount outstanding as per December 31, 2024 is €0.3 million. |
| ● | €0.5 million loan from Banco BPM S.p.A., with a fixed interest rate of 1.3% and final maturity in November 2026. Amount outstanding as per December 31, 2024 is €0.2 million. |
| ● | €3.0 million interest free loan from La Region Occitanie, with final maturity in October 2029. Final €2.1 million of the loan amount will be drawn in Q1 2025. Amount outstanding as per December 31, 2024 is €0.9. |
Loan Maturities
Years Ended December 31, | ||||||
(In € thousands) |
| 2024 |
| 2023 |
| 2022 |
Less than one year |
| 21,081 |
| 128,513 |
| 1,358 |
Between one and five years |
| 170,003 |
| 152,464 |
| 247,732 |
More than five years |
| 96,472 |
| 155,092 |
| 80,760 |
Total |
| 287,556 |
| 436,070 |
| 329,850 |
Other Contractual Obligations and Commitments
Our contractual obligations, other than the financing agreements and related interest rate swaps detailed in the “Liquidity and CapEx” section, consist mainly of lease obligations capitalized under IFRS 16. Lease obligations are our future minimum commitments under lease agreements within the scope of IFRS 16 and are reflected on the balance sheet in our audited consolidated financial statements included elsewhere in this annual report. Lease agreements, which were not recognized in accordance with the exemptions in IFRS 16, are not material and therefore not presented here. In addition, we regularly enter several smaller contractual obligations related to our operations or facilities, such as the supply of inventories, power supply and insurance. Our contractual obligations as of December 31, 2024, include lease obligations for lease liabilities of €53.6 million, reflecting our future minimum lease commitments. As of December 31, 2024, €2.1 million of the committed lease payments associated with lease liabilities and other lease obligations will occur in the next 12 months, €14.3 million between one and five years. The remaining lease payments of €37.3 million will occur within more than 5 years. For a full overview of other contractual obligations and commitments, please refer to Note 18 to the Financial Statements.
We license or acquire certain third-party intellectual property to utilize in our business. Under these agreements, we are required to pay milestones, dependent on development progress and/or royalties and milestones dependent on present and future net income or on sublicensing fees received from third parties. However, it is not possible to predict the maximum potential number of future payments under these agreements due to the conditional nature of our obligations and the unique facts and circumstances involved in each agreement. There are no off-balance sheet obligations other than those disclosed above.
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CapEx
Capital expenditure decreased significantly as planned to €(117.5) million in 2024 (2023: €(213.3) million), partially driven by reduced investments into Just – Evotec Biologics with €(92.6) million compared to €(128.5) million in 2023, where especially the investments into JPOD2 in Toulouse have decreased, as the facility is near completion. Within the Shared R&D segment, we invested €(24.9) million in 2024 (2023: €(84.8) million), where investments were limited to regular maintenance activities in order to maintain the highest technology and infrastructure standards for scientific operations and to finalize the new buildings in Hamburg and Manchester. Other investments were paused in alignment with the new strategy reset that is expected in Q2 2025.
For 2025, we plan to invest in the completion of our Just – Evotec Biologics facilities and continued maintenance capex in Shared R&D.
Comparative Cash Flows
The following table summarizes the primary sources and uses of cash for each period presented:
Year Ended December 31, | ||||||
(In € thousands) |
| 2024 |
| 2023 |
| 20221 |
Net cash flows provided by (used in): |
|
|
|
|
|
|
Operating activities |
| 18,220 | 36,439 | 205,811 | ||
Investing activities |
| (71,187) | (13,291) | (412,797) | ||
Financing activities |
| (161,421) | 71,963 | (58,145) | ||
Total cash (outflow)/inflow |
| (214,388) | 95,111 | (265,131) | ||
1 Interest received and interest paid have been reallocated from the operating cash flow to the investing cash flow and the financing cash flow. The previous year number from 2022 has been adjusted accordingly. The change was made to provide a clearer picture of the financial position.
Cash Flow from Operating Activities
Net cash flows from operating activities are primarily derived from partnered projects and the sale of products and services rendered. Our cash flows from operating activities are significantly influenced by our use of cash for operating expenses and working capital to support the business.
For the fiscal year ended December 31, 2024, operating activities generated €18.2 million in cash and cash equivalents. The main components of cash flow from operating activities include the net loss of € (196.1) million, offset by non - cash charges of €206.4 million, which included depreciation and amortization of €101.6 million and Gain on investment in financial instruments reevaluation of €39.5 million. Further, the changes in net working capital amounted to € (68.2) million.
For the fiscal year ended December 31, 2023, operating activities generated €36.4 million in cash and cash equivalents. Net Loss amounted to € (83.9) million, after consideration of non - cash charges of €143.2 million. The non - cash charges included depreciation and amortization of €93.0 million and Share of loss (profit) and reevaluation of at - equity investments of €20.8 million. Further, the changes in net working capital amounted to € (9.9) million.
Cash Flow from Investing Activities
During the year ended December 31, 2024, cash used in investing activities amounted to €71.2 million which consisted of purchases of short-term investments in the amount of €29.4 million, purchases of investments in associated companies and other long-term investments of €(15.1) million, divestment of affiliated companies of €(11.5) million, sale of investment in Recursion Pharmaceuticals, Inc. of €69.4 million, purchases of property, plant and equipment in the amount of €117.5 million (including in respect of €92.6 million invested in Just – Evotec Biologics) and €35.7 million of proceeds from the sale of current investments, purchase of intangible assets and capitalization of development expenditures of €(14.8) million, as well as proceeds from the sale of property, plant and equipment of €2.0 million.
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During the year ended December 31, 2023, cash used in investing activities amounted to €13.3 million which consisted of purchases of short-term investments in the amount of €48.4 million, purchases of investments in associated companies and other long-term investments of €(23.6) million, divestment of investments in associated companies and minorities of €1.4 million, purchases of property, plant and equipment in the amount of €213.3 million (including in respect of €110.2 million invested in the J.POD EU facility in Toulouse) and €260.4 million of proceeds from the sale of current investments, as well as proceeds from the sale of property, plant and equipment of €0.5 million.
Cash Flow from Financing Activities
Our primary financing activities consist of issuances of share capital, proceeds from/payments of bank loans and payments of finance lease liabilities.
Net cash provided in 2024 in financing activities for the year ended December 31, 2024 was €(161.4) million which consisted of R&D and investment financing of €(128.8) million and repayment of lease obligations amounting to €(24.1) million. The repayment of loans included mainly the repayment of revolving credit lines. Proceeds from option exercise amounted to €0.4 million.
Net cash provided in 2023 in financing activities for the year ended December 31, 2023 was €72.0 million which consisted of R&D and investment financing of €112.9 million, proceeds from loans of €219.9 million and repayment of lease obligations amounting to €22.4 million. The repayment of loans included mainly the repayment of revolving credit lines. Proceeds from option exercise amounted to €0.2 million.
| C. | Research and development, patents and licenses, etc. |
[See Item 4 “Business Overview” and “Operating and Financial Review and Prospects—A. Operating Results” in this Item 5.]
| D. | Trend information. |
See the description of “Operating Results” in this Item 5 within this annual report.
| E. | Critical Accounting Estimates. |
The consolidated financial statements have been prepared in accordance with IFRS and its interpretations as issued by the IASB. For a discussion of our significant accounting policies and other estimates, please see “Summary of significant accounting policies” in note 2 in the notes to our consolidated financial statements included in this annual report.
Item 6. Directors, Senior Management and Employees
| A. | Directors and senior management |
Two-Tiered Board Structure
We are a European public company with limited liability (Societas Europaea or “SE”) (also referred to as European stock corporation, and in the official terminology of the European legislation referred to as European public limited-liability company), having its seat in Germany with a two-tiered governance structure. Hence, our corporate bodies are the Management Board (Vorstand), the Supervisory Board (Aufsichtsrat) and the shareholders’ meeting (Hauptversammlung). Our Management and Supervisory Boards are entirely separate, and, as a rule, no individual may simultaneously be a member of both boards.
Our Management Board is responsible for the day-to-day management of our business in accordance with applicable laws, our Articles of Association (Satzung) and the Management Board’s internal rules of procedure (Geschäftsordnung des Vorstands).
The principal function of our Supervisory Board is to supervise our Management Board. The Supervisory Board is also responsible for appointing and removing the members of our Management Board, representing us in connection with transactions between a current or former member of the Management Board and us, and reviewing and approving when appropriate certain significant matters.
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Management Board (Vorstand)
The following table sets forth the names and functions of the current members of our Management Board, their ages:
Name |
| Age |
| Position |
Werner Lanthaler, Ph.D. | 56 | CEO (until Jan 2024) | ||
Mario Polywka, D.Phil. | 62 | CEO (from Jan to June 2024) | ||
Christian Wojczewski, Ph.D | 53 | CEO (since July 2024) | ||
Aurélie Dalbiez | 47 | Chief People Officer (“CPO”; since June 2024) | ||
Cord Dohrmann, Ph.D. | 61 | Chief Scientific Officer (“CSO”) | ||
Matthias Evers, Ph.D | 51 | Chief Business Officer (“CBO”; until Sep 2024) | ||
Craig Johnstone, Ph.D. | 55 | Chief Operating Officer (“COO”; until Dec 2024) | ||
Laetitia Rouxel | 52 | Chief Financial Officer (“CFO”; since April 2023) |
The business address of the members of our Management Board is the same as our business address: Essener Bogen 7, 22419 Hamburg, Germany.
The following is a summary of the business experience of the members of our Management Board (as of December 31, 2024):
Dr. Christian Wojczewski joined Evotec as CEO on July 1, 2024. Dr. Wojczewski has over 20 years of experience in various management positions, most recently at Mediq and Linde Healthcare. In 2017, he joined Mediq in the Netherlands, a European leader in medical devices and related services, as group CEO. In 2005, he joined Linde, a global market leader for medical and industrial gases. Previously, he worked as a Manager at McKinsey for companies in the life science and chemical industries in Europe and the US. Dr. Wojczewski holds a Diploma and a doctorate in chemistry from the Johann Wolfgang Goethe-University in Frankfurt am Main.
Dr. Cord Dohrmann has served as CSO of Evotec since September 2010. From 2000 to 2010, Dr. Dohrmann served in various management positions including as the Chief Scientific and CEO at DeveloGen AG, a drug discovery company focused on the development of novel therapies for diabetes and obesity. Evotec acquired DeveloGen in 2010. Dr. Dohrmann serves on the Supervisory Board of Eternygen GmbH and Breakpoint Therapeutics. Dr. Dohrmann is a member of the German Council of Science and Humanities. He is also a non-executive member of the Board of FSHD (Facioscapulohumeral Muscular Dystrophy) Unlimited in Leiden, the Netherlands. Dr. Dohrmann holds an undergraduate degree in biology from Tübingen University, a master’s degree in molecular biology from the Max-Planck Institute and a doctorate in cellular and molecular biology from Harvard Medical School.
Dr. Craig Johnstone has served as COO of Evotec since January 2019 until December 31, 2024. Dr. Johnstone joined Evotec in 2012 as the Senior Vice President of Drug Discovery and Innovation Efficiency. In 2015, he was appointed Directeur General and Site Head of Evotec (France) SAS and, in January 2017, he became the Global Head of Integrated Drug Discovery. Dr. Johnstone does not hold any memberships in supervisory bodies. Dr. Johnstone holds a bachelor’s degree in pure and applied chemistry, as well as a doctorate degree in organic and organometallic synthesis from the University of Strathclyde.
Laetitia Rouxel was appointed as CFO from April 2023 with oversight over various functions and departments, including finance, legal and compliance, internal audit, and risk management. Before joining Evotec, she was Global CFO of Wavin Group, a solutions leader for the building and infrastructure industry. A graduate of the French Business school ISG, she started her career with finance and commercial roles in the Pharma industry at Pfizer Pharmaceuticals and Johnson & Johnson. She went on to work for the French food-products corporation Danone, and then joined the beauty company Coty in Switzerland as divisional CFO.
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Aurélie Dalbiez was appointed as CPO of Evotec on June 15, 2024. Aurélie is responsible for the development and implementation of Evotec’s people strategy, focusing on fostering a culture of innovation, collaboration and belonging. Prior to joining Evotec, Aurélie served as the Chief Human Resources Officer (“CHRO”) at Corbion N.V., a global bio-based ingredients company headquartered in Amsterdam, Netherlands. Previously, she was Head of HR for the Capsules and Health Ingredients business at Lonza, based in Basel, Switzerland. Prior to that, she worked for 12 years in various HR roles at Novartis. She started her career in the banking industry, first at Deutsche Bank and later at Capital Group. She earned her university degree in International Business in Lyon, France.
Supervisory Board (Aufsichtsrat)
The following table sets forth the names and functions of the members of our Supervisory Board, their ages, their terms (which expire on the date of the relevant year’s general shareholders’ meeting) and their principal occupations outside of our Company:
Name |
| Age |
| Position |
Prof. Dr. Löw-Friedrich | 64 | Chief Medical Officer and Executive Vice President of UCB S.A. | ||
Camilla Macapili Languille | 41 | Head of Life Sciences, Mubadala Investment Company | ||
Dr. Elaine Sullivan (until June 2024) | 64 | Independent consultant; CEO of KELTIC Pharma Therapeutics Ltd. (until May 2023) | ||
Dr. Constanze Ulmer-Eilfort | 62 | Partner at PSP München | ||
Roland Sackers | 56 | CFO and Managing Director at QIAGEN N.V. | ||
Dr. Mario Polywka (until June 2024)1 | 62 | Independent consultant and former member of the Management Board of Evotec SE | ||
Dr. Duncan McHale (since June 2024) | 58 | Founder and Company Director of Weatherden Ltd, London, UK | ||
Wesley Wheeler (since June 2024) | 68 | Operating Advisor to KKR, Madison Dearborn Partners and Edgewater Capital |
The business address of the members of our Supervisory Board is the same as our business address: Essener Bogen 7, 22419 Hamburg, Germany.
The following is a summary of the prior business experience of the members of our Supervisory Board (as of December 31, 2024) :
Prof. Dr. Iris Löw-Friedrich has served as a Member of the Supervisory Board at Evotec since June 2014, her appointment to Chairwoman of the Supervisory Board of Evotec SE took place in 2021. Since 2008, Prof. Dr. Löw-Friedrich has served as Chief Medical Officer and Executive Vice President of Development and Medical Practices at UCB S.A., Brussels (Belgium), a biopharma company focusing on neurology and immunology. Since April 2014, Prof. Dr. Löw-Friedrich has served as a Member of the Board of Directors at TransCelerate BioPharma Inc. and, since May 2016, as a Member of the Supervisory Board of Fresenius SE & Co. KGaA. She is also a member of the Board of Directors at PhRMA Foundation in Washington D.C., United States. Prof. Dr. Löw-Friedrich holds a doctorate degree in medicine from the University of Frankfurt.
1 Dr. Mario Polywka was a member of the Supervisory Board throughout Financial Year 2023. Between January 15, 2024, and June 30, 2024 his mandate at the Supervisory Board was paused due to his assignment as interim CEO of the Company
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Camilla Macapili Languille was appointed a Member of the Supervisory Board in June 2022. She leads the unit for Life Sciences investments at Mubadala Investment Company (“MIC”), a sovereign wealth fund based in Abu Dhabi. Before joining Mubadala, Camilla Macapili Languille worked in M&A for Daiwa Capital and Société Générale in Paris, France, where she specialized in cross-border transactions in various sectors. She began her career in healthcare M&A at JPMorgan in New York and London, where she focused on pharma and biotech. She also serves as a Member of the Board of Directors at PCI Pharma Services (KPCI Holdings Limited), Philadelphia/United States (not listed), at Norstella (Caerus PikCo S.A.R.L.), New York/US- listed) (until December 2023), at Envirotainer A/S, Stockholm/Sweden (not listed) and since December 2023 at va-Q-tec AG, Würzburg/Germany(listed on the Frankfurt Stock Exchange until August 30, 2023). Camilla Macapili Languille holds a Bachelor of Economics & Political Science degree from Columbia University.
Roland Sackers has served as a Member of the Supervisory Board since June 2019 and is chairman of the audit committee. Since 2004, Mr. Sackers has been CFO of QIAGEN N.V. In 2006, Mr. Sackers became a member of the Managing Board. Between 1995 and 1999, he served as an auditor with Arthur Andersen Wirtschaftsprüfungsgesellschaft Steuerberatungsgesellschaft. He is a former member of the supervisory board and audit committee of IBS AG and a former member of the board of directors of Operon Biotechnologies, Inc. Mr. Sackers is as a board member of the industry association BIO Deutschland. He was previously a non-executive director and chair of the audit committee from 2011 to 2018 of Immunodiagnostic Systems Holding PLC (IDS), a leading producer of immunological tests for research and diagnostic applications publicly listed in the United Kingdom. Mr. Sackers earned his Diplom-Kaufmann from University of Münster, Germany.
Dr. Constanze Ulmer-Eilfort was appointed a Member of the Supervisory Board in June 2021. As a Partner with the law firm Peter, Schönberger & Partner (PSP München), she advises on a wide range of agreements, including cooperation and licensing agreements, R&D agreements and agreements with academic institutions. Previously, since 1994, Dr. Ulmer-Eilfort has worked at Baker McKenzie serving in several roles, including as Equity Partner since 2000, Member of the Global Executive Committee between 2017 and 2021, and as Managing Partner in the German and Austrian offices from 2012 to 2017. She serves as a Member of Supervisory Board at Affimed NV, Mannheim/Germany (listed on the NASDAQ) and as a Member of the Advisory Board at Proxygen GmbH, Vienna/Austria (not listed). Dr. Ulmer-Eilfort also serves as Chair of the Advisory Committee at S4DX GmbH, a biotechnology start-up based in Munich since May 2021. Dr. Ulmer-Eilfort holds a law degree from the University of Munich, a Master of Laws degree from the University of Pennsylvania Law School, and a doctorate degree in law from the University of Berlin.
Dr. Duncan McHale was appointed a Member of the Supervisory Board in June 2024. He is the Founder and Company Director of Weatherden Ltd, based in London, UK, a position he has held since 2017. Prior to this, Duncan served as the Chief Medical Officer at Evelo Biosciences from 2017 to 2023. From 2011 to 2017, he was the Vice President and Head of Global Exploratory Development at UCB. Between 2008 and 2011, he held various positions at AstraZeneca, culminating in the role of Vice President of Personalized Healthcare and Biomarkers. His career also includes several roles at Pfizer from 1999 to 2007, with his most recent position being Executive Director, European Head of Molecular Profiling and TA lead for Pain, Sex Health, and Urology at Pfizer Global Research and Development’s Sandwich Laboratories. Duncan holds a Doctor of Philosophy (“PhD”) in Human/Medical Genetics from the University of Leeds, and earned his Bachelor of Medicine, Bachelor of Surgery from the University of Newcastle-Upon-Tyne.
Wesley Wheeler was appointed a Member of the Supervisory Board in June 2024. In his final three years at UPS, Wesley was named President of UPS Healthcare, the first vertical business unit ever created at UPS, which is a global leader in the clinical trials services industry. Previously, Wesley accepted a role as CEO of Marken, a leading privately held clinical trials logistics company. Between 2007 and 2010, he became CEO of Patheon (now a ThermoFisher company), a public company traded on the Toronto Stock Exchange. Overall, Wesley Wheeler is a 43 - year operations executive starting as a project engineer with Exxon Research & Engineering (now ExxonMobil), but for the past 34 years has held many diverse leadership positions in the pharmaceutical industry. Wesley holds a bachelor’s degree in mechanical engineering and a Masters of Business Administration.
Changes in the Management Board and Supervisory Board
On January 15, 2024, Dr Mario Polywka has agreed to step in as interim CEO after Dr Werner Lanthaler stepped down as CEO. His Supervisory Board mandate was inactive while he worked in his role as interim CEO. Management Board transition completed on July 1, 2024, with Dr Christian Wojczewski taking over as CEO from interim CEO Dr Mario Polywka. Since June 15, 2024 Aurélie Dalbiez is appointed as new CPO, a position that did not exist on the Management Board before. With effect as of September 30, 2024, Dr Matthias Evers resigned as CBO. With effect as of December 31, 2024, Dr Craig Johnstone resigned as COO. Both positions are currently not replaced.
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Wesley Wheeler and Duncan McHale elected to the Supervisory Board on June 10, 2024, at our Annual General Meeting (“AGM”) following Dr Elaine Sullivan and Dr Mario Polywka who resigned from Supervisory Board with effect of the AGM.
Family Relationships
No family relationships or other arrangements exist among any members of our Management Board or Supervisory Board.
| B. | Compensation. |
Remuneration report 2024 for Evotec SE
The following remuneration report presents and explains the remuneration awarded and owed to the individual present and former members of the Management Board and Supervisory Board of Evotec SE (hereafter also known as “Company”) in the financial year 2024. The remuneration report meets the requirements of Sec. 162 German Stock Corporation Act (Aktiengesetz - “AktG”). This remuneration report will be presented for approval at the ordinary AGM on June 3, 2025.
Resolution approving a remuneration system for the Executive Board and the Supervisory Board members.
The structure of remuneration and the amounts paid to the Management Board members are defined and regularly reviewed by the Supervisory Board. The review follows the recommendations of the German Corporate Governance Code (“GCGC”) as amended on April 28, 2022 and meets the requirements of Section 87 AktG.
The Company’s Supervisory Board, with the support of the Remuneration and Nomination Committee, presented a remuneration system for the members of the Company’s Management Board (the “Remuneration system 2022”) to the AGM on June 22, 2022, for approval. The AGM 2022 approved the Remuneration system 2022 by a majority of 94.48% of votes cast. The Remuneration system 2022 can be viewed on the website of Evotec SE at https://www.evotec.com/en/investor-relations/governance.
The Remuneration system 2022 applies to all the members of the Company’s Management Board whose contract was signed or renewed after the Remuneration system 2022 came into effect at the AGM 2022. As of December 31, 2024, this was Dr Cord Dohrmann, Laetitia Rouxel, Aurélie Dalbiez and Christian Wojczewski. The contracts with Dr Craig Johnstone and Dr Matthias Evers were signed in January 2022 and May 2022, so before the new remuneration came into effect. Both contracts were terminated ahead of schedule. The contract with Dr Werner Lanthaler ran from March 2021 until its early termination in January 2024. Since the contracts signed before the new remuneration system 2022 took effect still included the award of discretionary restricted shares at the start of the contract, the Supervisory Board decided not to renew these contracts early, but rather to wait until they expire and then structure any follow-on contracts in accordance with the new remuneration system.
The Company’s AGM on June 10, 2024, confirmed the remuneration of the Supervisory Board members last amended by resolution of the AGM 2024 with a majority of 96.23% and adopted a corresponding remuneration system for the Supervisory Board members.
Changes in the Management Board and Supervisory Board
With effect from January 3, 2024, the Chairman of the Management Board Dr Werner Lanthaler, has informed the company that he was stepping down as CEO and would not fulfill his contract until the end of the current term. The Supervisory Board accepted his resignation and appointed Dr Mario Polywka, former COO and member of the Supervisory Board at the time of the CEO’s departure, as interim CEO. Christian Wojczewski was appointed as new CEO for three years with effect from July 1, 2024.
Aurélie Dalbiez was appointed as Chief People Officer for a term of three years effective June 15, 2024.
Dr Elaine Sullivan and Dr Mario Polywka stepped down from the Supervisory Board at the company’s AGM on June 10, 2024. The AGM elected Dr Duncan McHale and Wesley Wheeler to the Supervisory Board and confirmed the remaining members of the Supervisory Board.
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Remuneration system for Management Board members of Evotec SE
Overview of the changes to the remuneration system in 2024
After intensive discussions with shareholders, the Supervisory Board decided to submit a revised and updated remuneration system for the members of the Management Board to the AGM 2022 for approval, which was approved with 94.48 % of the votes in favor. We reported in detail on the adjustments in the 2022 remuneration report. In 2024, this remuneration system was not changed.
The remuneration system 2022 applies to all members of the company’s Management Board still acting on December 31, 2024.
The remuneration report for 2023 was approved by the AGM 2024 with 84.87% of votes in favor.
Overview of main remuneration components
The remuneration of Management Board members is made up of a fixed basic salary, a short-term annual bonus, and the long-term, multi-year remuneration. In individual cases, additional remuneration may be granted in connection with the commencement and termination of service as a member of the Management Board, in particular in compensation for lost earnings from previous employers. Other components of the remuneration system are ancillary benefits, including pension contributions, and the payment of travel expenses. Any expenses incurred are counted towards the maximum remuneration.
A strong focus on the growth targets for the Evotec Group – consisting of Evotec SE and its affiliated companies – in the short-term variable remuneration (bonus) and a clear alignment of long-term variable remuneration with the share performance (Share Performance Awards - “SPA”) are intended to encourage sustainable increases in enterprise value and avoid external and internal disincentives. In particular the aim is to prevent the Management Board from making decisions that do not promise any sustainable commercial success in order to optimize their remuneration in the short term.
The amount of Management Board remuneration depends in particular on the responsibilities of the respective Management Board members, their individual and collective performance and the economic, financial, strategic and sustainability performance of the Evotec Group. It is intended to incentivize sustainable, long-term corporate governance and align the interests of the Management Board members with those of Company shareholders.
The remuneration of the Management Board members meets the requirements of the German Stock Corporation Act and the German Corporate Governance Code in effect at the time the respective employment contracts were signed (unless any exception is mentioned). In January 2025 respectively May 2025 the Management Board and Supervisory Board of Evotec SE updated the Declaration of Compliance pursuant to Art. 9 (1) c) ii) SE Regulation in conjunction with Section 161 AktG on the recommendations of the GCGC and made the following additions:
“Notwithstanding the recommendations G.6 and G.10, Dr Mario Polywka receives no long-term, share-based variable remuneration under the remuneration system for the Management Board for his temporary work as interim CEO from January 2024. Since he is only a member and Chair of the Management Board on an interim basis for up to one year, the Supervisory Board of Evotec SE does not believe that it reflects his interests and those of the Company to award him long-term variable remuneration whose measurement period would go well beyond his term of office on the Management Board, and therefore beyond the time for which he is able to influence the achievement of the performance targets. The spirit of the German Stock Corporation Act and the German Corporate Governance Code is also intended to prevent the incentives set by long-term share-based remuneration for provisional work on the Management Board from remaining in effect once the person has returned to the Supervisory Board, possibly giving rise to doubts about the independent exercise of its control function as a result. It is already in Dr Mario Polywka’s interest to promote the Company’s long-term welfare and to ensure its sustainable long-term performance, because after completing his interim work on the Management Board he will return to the Supervisory Board, and so requires no further incentives to do so. Once Dr Mario Polywka has finished his provisional work on the Management Board, the remuneration of the Management Board will once again comply fully with the recommendations of the Code.”
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In May 2024, the Supervisory Board partially redefined the performance criteria for the members of the Management Board for the short-term variable remuneration components (bonus) in application of recommendation G.11, in deviation from recommendation G.8. In doing so, the Supervisory Board took into account the forecast for 2024 published on April 24, 2024, which differs significantly from the forecast originally provided in December 2023 for the performance criteria for the bonus 2024. This gives the Supervisory Board the opportunity to adjust the incentivization effect of the variable annual remuneration and an adequate performance measurement to the significantly changed factors, to align them with the interests of the company, and thus to ensure that the interests of investors and Management Board members are aligned, serving the long-term advancement of the company’s well-being and ensuring sustainable and long-term corporate success.”
In fact, Dr Mario Polywka decided not to return to the Supervisory Board and resigned from the Management Board and Supervisory Board at the AGM 2024.
The Supervisory Board, with the support of its Remuneration and Nomination Committee, regularly gathers external expertise to review the appropriateness of the Management Board’s remuneration in terms of the amount, reasonableness, and market conformity of the Management Board’s remuneration. To determine if the Management Board’s remuneration is appropriate in a vertical comparison, i.e. within Evotec SE, the Supervisory Board looked particularly at changes in the remuneration of senior managers and the workforce overall, also over time. The Supervisory Board monitors the level of Management Board remuneration at similar companies. The peer group1 used for the last comparison in 2021 comprised German and international biotech and pharmaceutical companies of a similar size and complexity in order to reflect Evotec’s global presence and potential markets for recruiting Management Board members. In future the benchmark used for the market comparison should be based on a peer group of German companies of a similar size and an additional peer group of international companies of similar size in a similar sector. The peer group from 20212 still applies to the financial year 2024. The current peer group is also disclosed prospectively in the respective remuneration report.
Non-performance-related fixed remuneration components
Basic salary
The Management Board members receive a contractually agreed fixed basic salary that is paid in twelve monthly installments at the end of each month with the statutory payroll deductions. Basic salary is paid pro rata temporis if the Management Board member joins or leaves in the course of the year.
The following table shows the annual basic salary for the Executive Board members in financial year 2024:
|
| Basic salary 2024 |
| Basic salary 2023 | ||
Executive Board member | Function | (in € k) | (in € k) | |||
Dr. Werner Lanthaler |
| CEO |
| 25 |
| 600 |
Mario Polywka | CEO | 306 | — | |||
Dr. Christian Wojczewski |
| CEO |
| 450 |
| — |
Aurélie Dalbiez | CPO | 244 | — | |||
Dr. Cord Dohrmann | CSO |
| 450 |
| 450 | |
Dr. Matthias Evers |
| CBO |
| 300 |
| 400 |
Dr. Craig Johnstone | COO | 400 | 400 | |||
Laetitia Rouxel |
| CFO |
| 450 |
| 338 |
1)Abcam, Bachem, Biotest, Carl Zeiss Meditec, Charles River, Clinigen, Galapagos, Genmab, Ligand, Morphosys, QIAGEN, Siegfried Pharma, Stallergenes, Sartorius, Tecan and MedPace.
2)See Footnote 1.
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Ancillary benefits
In addition to their fixed basic salary the Management Board members receive individual ancillary benefits, such as pension contributions and school fees for their own children, travel expenses, health and accident insurance, and the monetary value of their private use of a company car or a private car allowance. Furthermore, the Supervisory Board may at its professional discretion and having determined a significant additional need, refund the expenses for extraordinary ancillary benefits (e.g. security measures) on a temporary basis.
|
| Retirement pension |
| Car allowance |
| Travel expense |
| Other | ||
Executive Board member | Function | contributions in (€ k) | (in € k) | allowance (in € k) | (in € k)3 | |||||
Dr. Werner Lanthaler |
| CEO |
| 3 |
| 1 |
| 3 |
| — |
Dr. Christian Wojczewski |
| CEO |
| 60 |
| 8 |
| 53 |
| — |
Aurélie Dalbiez | CPO | 19 | — | 33 | 23 | |||||
Dr. Cord Dohrmann | CSO |
| 35 |
| 15 |
| — |
| — | |
Dr. Matthias Evers |
| CBO |
| 26 |
| 11 |
| — |
| — |
Dr. Craig Johnstone | COO | 27 | 15 | 0 | — | |||||
Laetitia Rouxel |
| CFO |
| 35 |
| 0 |
| 60 |
| 202 |
1) | Other fringe benefits include various insurance policies for the Management Board members based in Germany. |
Compensation payments
In addition, the members of the Management Board may be granted one-off benefits such as special benefits on joining the company, e.g. as compensation for lost earnings with the previous employer or for projects that have been stopped. Payments to a Management Board member in the event of premature termination of the employment contract without good cause for the termination of the Management Board activity are limited to a maximum of two years’ remuneration and do not exceed the annual remuneration for the remaining term of the employment contract (severance payment cap). If the employment contract is terminated for good cause for which the Management Board member is responsible, no payments are made to the Management Board member.
The following table shows a breakdown of the compensation payments made per Executive Board member in the 2024 financial year:
|
|
| Compensation payments1,2 | |
Executive Board member |
| Function |
| (in € k) |
Dr. Werner Lanthaler |
| CEO (until January 2024) |
| — |
Mario Polywka |
| CEO (from January until June 2024) |
| — |
Dr. Christian Wojczewski |
| CEO (since July 2024) |
| 500 |
Aurélie Dalbiez |
| CPO (since June 2024) |
| 150 |
Dr. Cord Dohrmann |
| CSO |
| — |
Dr. Matthias Evers |
| CBO (until September 2024) |
| — |
Dr. Craig Johnstone |
| COO (until December 2024) |
| 1,360 |
Laetitia Rouxel |
| CFO |
| 300 |
1) “Sign On” compensation: €500,000 Christian Wojczewski; €150,000 Aurelie Dalbiez; €300,000 Laetitia Rouxel;
2) Compensation: €1,360,000 Craig Johnstone
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Performance-related variable remuneration components
In line with the principles mentioned above, the Management Board remuneration is linked to Company performance and sustainable Company growth. Under the Remuneration system 2021 that applied until the AGM 2022, the Management Board remuneration comprised both short-term, annual remuneration (“bonus”) and long-term remuneration components (Share Performance Plan 2017 and Restricted Share Plan 2020), which were approved by the AGMs in 2017 and 2020. Payments for these components depend on achieving defined financial targets. If the targets are not achieved the payment of performance-based components may be reduced to zero. If the targets are significantly outperformed, however, the amount of the payment is capped. When the new Remuneration system 2022 took effect, the link to Company performance and sustainable Company growth described above was maintained, but the Restricted Share Plan 2020 is no longer part of the long-term remuneration component. The Share Performance Plan 2017 was replaced by the Share Performance Plan 2022, under which SPAs were granted for the first time in the financial year 2023 and then also in the financial year 2024. In addition, the bonus regulation was also adjusted. This regulation applies to Dr Christian Wojczewski, Aurélie Dalbiez, Dr Cord Dohrmann, and Laetitia Rouxel.
Short-term, one-year remuneration (bonus)
The Management Board members receive a short-term, one-year remuneration (bonus) that rewards the operational implementation of the Evotec Group strategy in the financial year as the foundation for the Company’s positive long-term development. The bonus depends on the achievement of specific financial and non-financial targets set for each financial year by the Remuneration and Nomination Committee of the Supervisory Board and then approved by the Supervisory Board. The bonus is paid pro rata temporis if the Management Board member joins in the course of the year.
A target amount is set for each Management Board member, which defines the amount of the bonus payment if the target achievement is 100%. In the remuneration system still applicable in 2021 for Dr Johnstone and Dr Evers, the target amount for the one-year variable remuneration is 70% of the annual base salary (2022: 70%). By eliminating the Restricted Share Plan 2020 and redistributing part of it to the bonus it was possible to change the target amount in the remuneration system 2022 without increasing the total target remuneration. The target amount for the bonus that the CEO receives if he achieves exactly 100% of the annual bonus targets corresponds to around 70% of basic salary for the direct payment portion of the bonus and to around 105% for the deferred portion. The corresponding figures for the ordinary members of the Management Board are around 43% of basic salary for the direct payment portion of the bonus and around 65% for the deferred portion, which represents a ratio of 40:60 between the direct payment and the deferred portion of the bonus. The deferred portion of the bonus is invested in Evotec shares, which the Management Board members buy via a service provider and have to hold for at least three years. Evotec provides the total applicable amount for all Management Board members and sets the timeframe within which the service provider must make the purchases on behalf of the Management Board members. The service provider then makes the purchases and transfers the shares purchased to the securities accounts of the Management Board members at a uniform average price with a corresponding lock-up period.
At the beginning of the following financial year the Supervisory Board measures the achievement of the targets and determines the amount of the annual bonus.
Bonuses are agreed with Management Board members in their individual employment contracts. When the Management Board remuneration system 2022 was revised a maximum bonus payment of up to 150% of the target amount was made possible for the bonus plan. This cap has applied to the bonuses of all Management Board members since 2023.
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For financial year 2023 the Supervisory Board defined the following performance criteria and their weighting for all Management Board members:
2023 targets |
| Weighting |
|
Expand basic business |
| 50.0 | % |
● Total revenue growth >€850 million |
| 20.0 | % |
● Exceed stable Adjusted EBITDA > € 120 million | 20.0 | % | |
● Maintain operating cash flow > €50 million |
| 10.0 | % |
Develop EVOroyalty, EVOequity and accelerate technology pool for precision medicine |
| 25.0 | % |
● Build new joint alliances using the components of Action Plan 2025 (e.g., iPSC, PanOmics & PanHunter, …) (>€100 million technical value)) |
| 10.0 | % |
● Just — Evotec Biologics path to profitability relative to AP 2025 (<€ 15 million loss in 2023) |
| 10.0 | % |
● Clarification of the global qualitative leadership position within end-to-end R&D (customer loyalty and sales quality) |
| 5.0 | % |
ESG: Develop people, the Company and Best of Governance Sustainability, Leadership and Entrepreneurship |
| 25.0 | % |
● Implementation of the SBTi initiative at all sites and investment of 1% of turnover to achieve the SBTi targets |
| 5.0 | % |
● Conduct an employee survey by mid-2023. Define and communicate the resulting targets for 2024 and following year | 5.0 | % | |
• Assignment of sustainability champions at all sites to establish structures that promote sustainability and social goals, as well as sustainable site-specific projects | 15.0 | % |
The Supervisory Board has set the following performance criteria and their weighting uniformly for all members of the Management Board for the financial year 2024. In doing so, the Supervisory Board has redefined the performance criteria for the Management Board members for the short-term variable compensation components (bonus) in May 2024 with regard to total revenue and EBITDA as stated in the corporate governance declaration disclosed under Overview of main remuneration components.
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2024 targets1 |
| Weighting |
|
Expand basic business |
| 60.0 | % |
• Total revenue growth >€880 million | 20.0 | % | |
• Exceed stable Adjusted EBITDA >€100 million | 30.0 | % | |
• Achievement of operating cash flow break-even, adjusted for one-off restructuring costs | 10.0 | % | |
Building global leadership with the 2025 Action Plan and the 2030 Strategy | 20.0 | % | |
• Build new joint alliances (e.g., iPSC, PanOmics …) (>€1 billion business value) | 5.0 | % | |
• Just — Evotec Biologics becomes profitable with 2 J.POD’s in 2024 | 5.0 | % | |
• Establishment of a new organizational structure (Execute / Innovate fold-up) by the end of 2024 | 10.0 | % | |
ESG: Develop people, the Company and Best of Governance Sustainability | 20.0 | % | |
• Improve SOX compliance and digitalization for more efficient work for all employees - no more than 2 material weaknesses by the end of the year | 5.0 | % | |
• Significant improvement (>10%) in the second survey on engagement and implementation of 3 initiatives addressing the key points of the first survey | 10.0 | % | |
• Develop and commit to a Climate Transition Plan (“CTA”) that includes climate adaptation measures and measures beyond the value chain to achieve Scope 1, 2 & 3 Net-Zero by 2045 | 5.0 | % |
1 Adjusted as per SB resolution on May 15, 2024.
The adjusted EBITDA was calculated in accordance with the EBITDA published in the annual report and the specified definition therein.
The Supervisory Board defines a uniform percentage of target achievement for all the individual targets, which can be between 0% and 125%. The target achievement percentage is converted into a payment factor (“bonus payment factor”) of between 0% and 150%. The bonus payment factor is multiplied by the target bonus amount for each individual target in order to determine the amount of the bonus payment for each individual target. Ultimately, the bonus amount can vary between zero and 150% of the target bonus amount (capped at 100% in total for the CFO).
The bonus payment amounts for the individual targets are added to determine the total bonus payment amount.
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Bonus target achievement for 2023 was as follows:
2023 targets |
| Result |
| Weighting |
| Achievement |
|
Expand basic business |
| 50 | % |
| |||
● Total revenue growth >€850 million |
| ● €781.4 million |
| 15 | % | 13.2 | % |
● Exceed stable Adjusted EBITDA >€120 million | ● €66.4 million | 30 | % | 0.0 | % | ||
● Exceed stable Adjusted EBITDA >€120 million | ● €36.4 million |
| 5 | % | 0.0 | % | |
Develop EVORoyalty, EVOEquity and accelerate technology pool for precision medicine |
| 30 | % |
| |||
● Build new joint alliances using the components of Action Plan 2025 (e.g., iPSC, PanOmics & PanHunter, …) (>€100 million technical value) | ● >€100 million upfront from BMS Neuro Partnership and Sandoz plus significant milestones and royalty prospects |
| 10 | % | 100.0 | % | |
● Just — Evotec Biologics path to profitability relative to AP 2025 (<€ 15 million loss in 2023) |
| ● Q4 2023 close to profitability, enables a forecast / budget 2024 that achieve profitability as planned |
| 10 | % | 100.0 | % |
● Clarification of the global qualitative leadership position within end-to-end R&D (customer loyalty and sales quality) | ● 93% customer retention rate |
| 10 | % | 100.0 | % | |
ESG: Develop people, the Company and Best of Governance Sustainability, Leadership and Entrepreneurship |
| 20 | % |
| |||
● Implementation of the SBTi initiative at all sites and investment of 1% of turnover to achieve the SBTi targets | ● SBTi implemented at all sites, including investment of 1% of sales to achieve SBTi targets |
| 5 | % | 100.0 | % | |
● Conduct an employee survey by mid-2023. Define and communicate the resulting targets for 2024 and following year. |
| ● Employee survey conducted and results communicated |
| 10 | % | 100.0 | % |
● Assignment of sustainability champions at all sites to establish structures that promote sustainability and social goals, as well as sustainable site-specific projects | ● Sustainability champions designated at each site |
| 5 | % | 100.0 | % |
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The target achievement for the bonus for the financial year 2024 was as follows:
2024 targets |
| Result |
| Weighting | Achievement |
| Weighted Factor |
| |
Expand basic business | 60 | % | — | — | |||||
● Total revenue growth >€880 million |
| Total revenue 2024: €797.0m |
| 20 | % | 86.5 | % | 17.3 | % |
● Exceed stable Adjusted EBITDA >€100 million | Adjusted EBITDA 2024: €22.6m | 30 | % | 0 | % | 0 | % | ||
● Achievement of operating cash flow break-even, adjusted for one-off restructuring costs | Cash flow from operating activities 2024: €18.2m (2023: €36.4m) |
| 10 | % | 0 | % | 0 | % | |
Building global leadership with the 2025 Action Plan and the 2030 Strategy | 20 | % |
| ||||||
● Build new joint alliances (e.g., iPSC, PanOmics …) (>€1 billion business value) | BMS antiviral collaboration; Novo Nordisk cell therapy collaboration (total Deal Volume cannot be disclosed, > € 1bn) |
| 5 | % | 100.0 | % | 5.0 | % | |
● Just — Evotec Biologics becomes profitable with 2 J.PODs in 2024 |
| Positive EBITDA of €9.9m for Just - Evotec Biologics; revenue growth of 71.1% to €185.6m; opening of second J.POD in Toulouse on September 20, 2024 |
| 5 | % | 100.0 | % | 5.0 | % |
● Establishment of a new organizational structure (Execute / Innovate fold-up) by the end of 2024 | Financial reporting was adjusted and the Execute/Innovate division was dissolved. However, the organizational structure was not adjusted in 2024. This will only take place after the strategy update in 2025. |
| 10 | % | 0 | % | 0 | % | |
ESG: Develop people, the Company and Best of Governance Sustainability | 20 | % |
| ||||||
● Improve SOX compliance and digitalization for more efficient work for all employees - no more than 2 material weaknesses by the end of the year | Improvement compared to 2025 by reducing material weaknesses, but still at least 3 material weaknesses. |
| 5 | % | 0 | % | 0 | % | |
● Significant improvement (>10%) in the second survey on engagement and implementation of 3 initiatives addressing |
| Implementation initiative launched globally, functionally and at team level; second survey conducted in January 2025; engagement score decreased. |
| 10 | % | 0 | % | 0 | % |
● Develop and commit to a Climate Transition Plan (“CTA”) that includes climate adaptation measures and measures beyond the value chain to achieve Scope 1, 2 & 3 Net-Zero by 2045 | The project to conduct a climate risk assessment as a first important step to develop a Climate Transition Plan (CTA) was paused due to cost savings related to the strategic prioritization in 2024. In parallel, measures to reduce Scope 1 & 2 emissions were implemented (e.g. increasing the share of green electricity, installation of a heat pump in Verona) and Evotec is well ahead of schedule to achieve the short-term Scope 1 & 2 targets for 2032. |
| 5 | % | 0 | % | 0 | % | |
Total target achievement |
| 27.3 | % |
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Since the activity underlying the annual bonus for 2024 was fully performed in the financial year 2024, it is allocated to the remuneration granted and owed in the financial year 2024 within the meaning of Section 162 para. 1 sentence 2 no. 1 AktG and consequently reported in this remuneration report. In order to ensure a transparent and comprehensible presentation of the compensation granted to the members of the Management Board for a financial year, the annual bonus for the financial year 2023 is also voluntarily disclosed in this compensation report.
Total target achievement for the 2023 bonus is as follows: In view of the particular circumstances in the 2023 financial year, particularly the cyber-attack in April 2023, it was decided to set the total target achievement at just 50% for the whole company and so significantly below the actual target achievement.
|
| Target based on 100% target |
| Cap based on maximum target |
| (corresponds to |
| Bonus payment | |||||||||||
Floor based on 0% target achievement | achievement | achievement | total target achievement) | amount 2023 | |||||||||||||||
in % of basic | in % of basic | in % of basic | in % of basic | ||||||||||||||||
Executive Board member |
| in k € |
| salary |
| in k € |
| salary |
| in k € |
| salary |
| in% |
| in k € |
| salary |
|
Dr. Werner Lanthaler | — | 0.0 | % | 600 | 100.0 | % | 900 | 150.0 | % | 0.0 | % | 0 | 0 | % | |||||
Dr. Cord Dohrmann | — | 0.0 | % | 484 | 107.5 | % | 726 | 120.9 | % | 50.0 | % | 242 | 53.8 | % | |||||
Dr. Matthias Evers | — | 0.0 | % | 280 | 70.0 | % | 420 | 105.0 | % | 50.0 | % | 140 | 35 | % | |||||
Dr. Craig Johnstone | — | 0.0 | % | 280 | 70.0 | % | 420 | 105.0 | % | 50.0 | % | 140 | 35 | % | |||||
Laetitia Rouxel | — | 0.0 | % | 363 | 107.5 | % | 544 | 161.3 | % | 50.0 | % | 181 | 53.8 | % | |||||
Enno Spillner | — | 0.0 | % | 56 | 17.5 | % | 56 | 70.0 | % | 50.0 | % | 28 | 35 | % | |||||
In view of the economic situation, the Management Board in office for the financial year 2024 has waived its bonus. Pro-rata bonuses for target achievement in 2024were paid to Dr. Mario Polywka and Dr. Matthias Evers, who left the Management Board during the year:
Floor based on 0% target | Target based on 100% target | Cap based on maximum target | Bonus payment |
| |||||||||||||||
achievement | achievement1 | achievement1 | (Corresponds to total target | amount 20242 | |||||||||||||||
in % of basic | in % of basic | in % of basic | achievement) | in % of basic | |||||||||||||||
Executive Board member |
| in k € |
| salary |
| in k € |
| salary |
| in k € |
| salary |
| in % |
| in k € |
| salary | |
Dr. Werner Lanthaler | — | 0.0 | % | 600 | 100.0 | % | 900 | 150.0 | % | 0.0 | % | — | 0.0 | % | |||||
Mario Polywka3 | — | 0.0 | % | 306 | 100.0 | % | 459 | 150.0 | % | 27.3 | % | 84 | 27.3 | % | |||||
Dr. Christian Wojczewski1,2 | — | 0.0 | % | 1,575 | 175.0 | % | 2,363 | 150.0 | % | 0.0 | % | — | 0.0 | % | |||||
Aurélie Dalbiez1,2 | — | 0.0 | % | 484 | 107.5 | % | 726 | 161.3 | % | 0.0 | % | — | 0.0 | % | |||||
Dr. Cord Dohrmann1,2 | — | 0.0 | % | 484 | 107.5 | % | 726 | 161.3 | % | 0.0 | % | — | 0.0 | % | |||||
Dr. Matthias Evers3 | — | 0.0 | % | 210 | 70.0 | % | 315 | 105.0 | % | 27.3 | % | 57 | 19.1 | % | |||||
Dr. Craig Johnstone3 | — | 0.0 | % | 280 | 70.0 | % | 420 | 105.0 | % | 0.0 | % | — | 0.0 | % | |||||
Laetitia Rouxel1,2 | — | 0.0 | % | 484 | 107.5 | 726 | 161.3 | % | 0.0 | % | — | 0.0 | % | ||||||
1 Based on the remuneration system approved by the 2022 AGM, 60% of the bonus paid to Cord Dohrmann will be invested in shares, which must be held for at least three years.
2 Dr. Christian Wojczewski, Aurélie Dalbiez, Dr. Cord Dohrman and Laetitia Rouxel have waived payment of the 2024 bonus.
3 Dr. Mattias Evers and Mario Polywka receive a pro rata bonus in accordance with their term of office in 2024.
Long-term, multi-year variable remuneration
The Management Board members also receive long-term, multi-year remuneration in the form of their participation in various Company remuneration programs that extend over several years. There are two different share-based programs, with payments after a waiting period of four years. This incentivizes the individual Management Board members to contribute to the Company’s long-term, sustainable development and aligns their interests with those of shareholders. When the new Remuneration system 2022 took effect, the link to Company performance and sustainable Company growth described above was maintained, but the Restricted Share Plan 2020 is no longer part of the long-term remuneration component.
Share Performance Plan 2022
In addition to their variable one-year remuneration, the Management Board members are entitled to an annual allocation of SPA in accordance with the Share Performance Plan 2022. The Share Performance Plan is a key step for supporting the interests of the Company shareholders and developing a modern, long-term remuneration model, which complies with the current German Corporate Governance Code at the time of its inception.
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The number of SPA to be allocated is determined by dividing a fixed percentage of the Management Board member’s basic remuneration by the relevant market value of an SPA. By eliminating the Restricted Share Plan 2020 and redistributing part of it to the SPA, the remuneration system 2022 adopted at the AGM made it possible to change the target amount without increasing the total target remuneration. The target amount for the SPA is around 225% of basic salary for the CEO and around 163% for the other members of the Management Board. This was only applied to Dr Cord Dohrmann for financial year 2023, however, whereas the following percentages from the remuneration system 2021 applied to the other Management Board members: the target amount for the SPA corresponds to approximately 225% of the base salary for the Chairman of the Management Board and approximately 163% for the members of the Management Board. However, for the 2024 financial year, this only applied to Dr Cord Dohrmann and Laetitia Rouxel, while the percentages of the 2021 remuneration system of 91.5% of the basic remuneration (2023: 91.5%) still applied to Dr Matthias Evers and Dr Craig Johnstone.
The amount paid out for the SPA may not exceed 350% of the target amount when they are exercised (cap).
The following table shows the number of SPA awarded in financial year 2024:
Target amount for | Market value of one SPA at the | awarded in FY | ||||||
performance shares (SPA) | award date | 2024 | ||||||
% of basic | ||||||||
Executive Board member |
| in k € |
| salary |
| in € |
| units |
Dr. Werner Lanthaler | — | — | % | 22.70 | — | |||
Dr. Christian Wojczewski | — | — | 22.70 | — | ||||
Mario Polywka | — | — | 22.70 | — | ||||
Aurélie Dalbiez | — | — | 22.70 | — | ||||
Dr. Cord Dohrmann | 731 | 162.5 | % | 22.70 | 32,214 | |||
Dr. Matthias Evers |
| 600 |
| 150.0 | % | 22.70 |
| 26,432 |
Dr. Craig Johnstone | 600 | 150.0 | % | 22.70 | 26,432 | |||
Laetitia Rouxel |
| 731 |
| 162.5 | % | 22.70 |
| 32,214 |
The Share Performance Plan 2022 is based on a prospective, multi-year measurement period. For each allocation of SPA there is a period of four consecutive calendar years in which certain performance indicators are measured (performance measurement period). The AGM 2022 set two equally weighted KPIs for long-term value creation: the relative total shareholder returns (“TSR”) and revenue growth. This is supplemented by performance against an additional ESG target (modifier).
The performance indicators are measured for each year of the performance measurement period. The performance in a given year is fixed for the remainder of the vesting period.
At the end of the vesting period there is a minimum target for each of the two KPI that has to be achieved before (some of) the SPA can be exercised, and a maximum target after which all the SPA for that KPI (100%) may be exercised. One SPA entitles the bearer to subscribe for a maximum of two whole shares in Evotec SE.
Relative TSR is an indicator for the return on an investment in Company shares compared with an investment in the TecDAX. Relative TSR measure the return on an equity investment over time, including dividends and changes in the share price (positive and negative), adjusted for any share issues or splits. 100% of the key performance indicator TSR is achieved for a performance measurement period, i.e. four calendar years, when the TSR for the shares of the Company (average share price of the Company at the closing auction of Xetra trading (or a successor system) on the thirty (30) trading days at Frankfurt Stock exchange prior to the relevant date plus dividends, and adjusted for any equity issuance or share-splits, is at least 20 percentage points higher than the average TSR of the companies listed in the German TecDAX index (or a comparable stock index) during the same period. The minimum target for the performance target TSR is achieved when the TSR for the shares of the Company matches the average TSR of the companies listed in the TecDAX. The maximum target, at which all the SPAs for the performance indicator TSR can be exercised at a ratio of 1:2, is achieved when the annual average TSR for the shares of the Company is at least 60 percentage points above the average TSR of the companies listed in the TecDAX during the respective performance period.
Relevant values of the TSR of the Company and of the average To of the companies listed in the TecDAX will be calculated based on the average TecDAX (Total Return Index) during the thirty (30) trading days at Frankfurt Stock exchange prior to the relevant date.
65
100% of the key performance indicator “Group Revenue” is achieved (“Target Group Revenue”) when the cumulative growth in Group revenue of Evotec SE in the performance measurement period, i.e. four calendar years, corresponds to the cumulative growth in Group revenue of Evotec SE planned by the Management Board with the approval of the Supervisory Board on the basis of a mid-range plan. The Management Board, with the approval of the Supervisory Board, should generally prepare the mid-range plan for a five-year period every year, on the basis of a sustainable corporate development with demanding, relevant target parameters. The “performance measurement period” is the four-year period starting on January 1 of the year in which the individual tranche of the subscription rights is awarded. “Group Revenue” is the revenue in the consolidated income statement. Cumulative Group revenue, and so revenue growth, is calculated on the basis of the audited and approved consolidated financial statements (IFRS) of Evotec SE for the respective performance measurement period, less revenue from out licensed development programs. The minimum target for the performance indicator “Group Revenue” is achieved when the cumulative growth in Group revenue of Evotec SE in the performance measurement period is equal to or greater than 50% of the target Group revenue growth defined for the respective performance measurement period. The maximum target for the performance indicator “Group Revenue” is achieved when the cumulative growth in Group revenue of Evotec SE in the performance measurement period is equal to or greater than 150% of the target Group revenue growth defined for the respective performance measurement period.
The ESG modifier is a figure for measuring long-term research spending on socially relevant illnesses (e.g., infectious diseases or women’s health). The ESG modifier distinguishes between complete (modifier: 1.0) and incomplete target achievement (modifier: 0.9) and is multiplied by the sum of target achievement in the two performance indicators TSR and “Group revenue”. The Supervisory Board is authorized to determine the level of target achievement. The ESG target cannot be achieved by more than 100%.
If the minimum target for any performance indicator is not achieved, the corresponding number of SPA expires. If the target is exactly achieved (100% target achievement) the corresponding number of SPA are converted into the same number of subscription rights to shares in Evotec SE at the end of the performance period. If the maximum target is achieved (200% target achievement) the corresponding number of SPA are converted into twice the number of subscription rights to shares in Evotec SE at the end of the performance period. Between these figures the values are interpolated on a linear basis.
The Share Performance Plan 2022 works as follows:
66
The payout curves of the performance indicators revenue growth and relative TSR out performance are shown below:
The right to exercise the subscription rights resulting from converting the SPA only vests at the end of the performance period. At the end of the four-year performance period for the SPA the target achievement is measured for the two performance indicators, the corresponding number of subscription rights is calculated and fixed. There is no dividend equivalent.
Share Performance Plan 2017
The Share Performance Plan 2017 is based on a prospective, multi-year measurement period. For each allocation of SPA there is a period of four consecutive calendar years in which certain performance indicators are measured (performance measurement period). The AGM 2017 set two equally weighted KPI for long-term value creation: the share price and the relative TSR. Relative TSR is an indicator for the return on an investment in Company shares compared with an investment in the TecDAX. Relative TSR measure the return on an equity investment over time, including dividends and changes in the share price (positive and negative), adjusted for any share issues or splits. The performance indicators are measured for each year of the performance measurement period. The performance in a given year is fixed for the remainder of the vesting period.
At the end of the vesting period there is a minimum target for each of the two KPI that has to be achieved before (some of) the SPA can be exercised, and a maximum target after which all the SPA for that KPI (100%) may be exercised. One SPA entitles the bearer to subscribe for a maximum of two whole shares in Evotec SE.
The target for the share price increase in a calendar year is achieved exactly (100%) if the average price of the Evotec share in the closing auction of XETRA trading (or a successor system) on the last 30 trading days at the Frankfurt Stock Exchange in the relevant performance period, i.e. the calendar year (“closing price”) is more than 8% higher than the average price of the Evotec share in the closing auction of XETRA trading (or a successor system) on the last 30 trading days before the start of the relevant performance period (“opening price”). The minimum target is achieved if the closing price is the same as the opening price (0% target achievement). The maximum target is achieved in a calendar year if the closing price is 16% or more above the opening price (200% target achievement).
The KPI relative TSR measures the return on a share investment over a period of time, including dividends as well as share price performance (positive and negative) and adjusted for any equity issues or share-splits. The target for TSR is achieved exactly in a calendar year (100%) if the return on the Evotec share matches the average return on the shares of the companies listed in the TecDAX over the same period. The return on the Evotec share is determined on the basis of the closing price and the dividend per share paid in that year (adjusted for any equity issues and share-splits) in relation to the opening price:
67
The relevant values of the average relative TSR of the companies listed in the TecDAX will be calculated and based on the average TecDAX -(Total Return Index) during the thirty (30) trading days at Frankfurt Stock Exchange prior to the relevant date. The return is therefore based on the relation between the average TecDAX value in the closing auction of XETRA trading (or a successor system) in the last 30 trading days of the relevant performance period, i.e. the calendar year (“final value”) and the average TecDAX value in the closing auction of XETRA trading (or a successor system) on the last 30 trading days before the start of the relevant performance period (“starting value”).
The minimum target is achieved (0% target achievement) if the return on the Evotec share is less than 10% below the average TSR for the companies in the TecDAX in the relevant performance period (i.e. in each calendar year). The maximum target is achieved (200% target achievement) if the return on the Evotec share is at least 10% higher than the average total TSR for the companies in the TecDAX in the relevant performance period.
If the minimum target for one performance indicator is not achieved in a calendar year, the corresponding number of SPA (12.5% of the SPA granted at the start of the performance period) are forfeit. If the target is exactly achieved (100% target achievement) the corresponding number of SPA are converted into the same number of subscription rights to shares in Evotec SE at the end of the performance period. If the maximum target is achieved (200% target achievement) the corresponding number of SPA are converted into twice the number of subscription rights to shares in Evotec SE at the end of the performance period. Between these figures the values are interpolated on a linear basis.
The Share Performance Plan 2017 works as follows:
68
The payment curves for the KPI absolute share price performance and relative TSR are shown below:
The right to exercise the subscription rights resulting from converting the SPA only vests at the end of the performance period. At the end of each of the four performance periods (i.e. each calendar year) for the SPAs the target achievement is measured for the two performance indicators in the relevant calendar year, the corresponding number of subscription rights are calculated and provisionally fixed. At the end of all four performance periods, i.e. the four calendar years of an award, the subscription rights calculated for each year are added to obtain the total number of subscription rights. There is no dividend equivalent.
SPAs from the 2020 grant became exercisable in 2024. The following table shows the target achievement for the individual performance criteria per year and in aggregate:
Target achievement 2020 | Target achievement 2021 | Target achievement 2022 | Target achievement 2023 | Target achievement | |||||||
| (in %) |
| (in %) |
| (in %) |
| (in %) |
| (in %) |
| |
Relative share price performance | 200 | % | 200 | % | — | % | 200 | % | 150 | % | |
Relative TSR |
| 200 | % | 200 | % | — | % | 200 | % | 150 | % |
69
The target achievement for 2024 was 0% for each of the performance indicators. In accordance with the relevant Share Performance Plan 2017, both KPIs, the absolute share price performance and the relative TSR compared to the TecDAX, are based on publicly available information. For the sake of simplicity, the actual target achievement as well as the absolute targets and the target achievement per KPI are shown below:
| 2019 |
|
|
| 2020 |
| |
KPI “Share Price” | KPI “Share Price” |
| |||||
Average last 30 trading days 2018 |
| 18.371 |
| Average last 30 trading days 2019 |
| 20.587 | |
Average last 30 trading days 2018 |
| 20.587 |
| Average last 30 trading days 2020 |
| 26.713 | |
Increase |
| 9.91 | % | Increase |
| 29.76 | % |
KPI “Share Price” achievement |
| 124.0 | % | KPI “Share Price” achievement |
| 200.0 | % |
KPI “TSR” |
| KPI “TSR” | |||||
Evotec TSR 2019 vs. 2018 |
| 9.91 | % | Evotec TSR 2020 vs. 2019 |
| 29.76 | % |
TecDAX TSR 2019 vs. 2018 |
| 19.96 | % | TecDAX TSR 2020 vs. 2019 |
| 2.68 | % |
Relative TSR Evotec vs. TecDAX |
| (10.05) | % | Relative TSR Evotec vs. TecDAX |
| 27.07 | % |
KPI “TSR” achievement |
| 0.0 | % | KPI “TSR” achievement |
| 200.0 | % |
Overall performance achievement |
| 62.0 | % | Overall performance achievement |
| 200.0 | % |
| 2021 |
|
|
| 2022 |
| |
KPI “Share Price” | KPI “Share Price” |
|
| ||||
Average last 30 trading days 2020 |
| 26.713 |
| Average last 30 trading days 2021 |
| 41.558 | |
Average last 30 trading days 2021 |
| 41.558 |
| Average last 30 trading days 2022 |
| 16.125 | |
Increase |
| 55.57 | % | Increase |
| (61.20) | % |
KPI “Share Price” achievement |
| 200.0 | % | KPI “Share Price” achievement |
| 0.0 | % |
KPI “TSR” |
|
| KPI “TSR” |
|
| ||
Evotec TSR 2021 vs. 2020 |
| 55.57 | % | Evotec TSR 2022 vs. 2021 |
| (61.20) | % |
TecDAX TSR 2021 vs. 2020 |
| 23.74 | % | TecDAX TSR 2022 vs. 2021 |
| (21.54) | % |
Relative TSR Evotec vs. TecDAX |
| 31.84 | % | Relative TSR Evotec vs. TecDAX |
| (39.66) | % |
KPI “TSR” achievement |
| 200.0 | % | KPI “TSR” achievement |
| 0.0 | % |
Overall performance achievement |
| 200.0 | % | Overall performance achievement |
| 0.0 | % |
| 2023 |
|
|
| 2024 |
| |
KPI “Share Price” |
| KPI “Share Price” |
|
| |||
Average last 30 trading days 2022 |
| 16.125 |
| Average last 30 trading days 2023 |
| 19.382 | |
Average last 30 trading days 2023 |
| 19.382 |
| Average last 30 trading days 2024 |
| 8.942 | |
Increase |
| 20.20 | % | Increase |
| (53.87) | % |
KPI “Share Price” achievement |
| 200.0 | % | KPI “Share Price” achievement |
| 0.0 | % |
KPI “TSR” |
|
| KPI “TSR” |
|
| ||
Evotec TSR 2023 vs. 2022 |
| 20.20 | % | Evotec TSR 2024 vs. 2023 |
| (53.87) | % |
TecDAX TSR 2023 vs. 2022 |
| 6.82 | % | TecDAX TSR 2024 vs. 2023 |
| 6.54 | % |
Relative TSR Evotec vs. TecDAX |
| 13.38 | % | Relative TSR Evotec vs. TecDAX |
| (60.41) | % |
KPI “TSR” achievement |
| 200.0 | % | KPI “TSR” achievement |
| 0.0 | % |
Overall performance achievement |
| 200.0 | % | Overall performance achievement |
| 0.0 | % |
The final number of exercisable SPA from the 2020 grant is shown in the following table for each Executive Board member:
Target achievement rel. |
| Number of SPA in 2020 | Number of SPA from 2020 | |||||||||
Number of SPA awarded | share | Target achievement | tranche based on target | tranche actually exercised | ||||||||
Executive Board member |
| Function |
| from 2020 tranche |
| price performance (in %) | Relative TSR (in %) |
| achievement |
| (subject to remuneration cap) | |
Dr. Werner Lanthaler |
| CEO |
| 38,400 |
| 150 | % | 150 | % | 57,600 |
| 57,600 |
Dr. Cord Dohrmann |
| CSO |
| 14,647 |
| 150 | % | 150 | % | 21,971 |
| 21,971 |
Dr. Craig Johnstone |
| COO |
| 12,450 |
| 150 | % | 150 | % | 18,675 |
| 18,675 |
One SPA corresponds to one Evotec share, which at the time of exercise in January 2024 was trading at about € 15/share.
Restricted Share Plan 2020
In the event of unusual circumstances, relating above all to competition, the Supervisory Board could at its professional discretion and having determined that it is appropriate, grant additional Restricted Share Awards if this was expected to have a positive influence on the long-term performance of the Evotec Group. The Supervisory Board determines the target amount of Restricted Share Awards in the individual case. The amount of the Restricted Share Awards may not exceed 400% of the target amount (cap).
70
Active discussions with shareholders gave the Supervisory Board to understand that the Restricted Share Plan 2020 and the Supervisory Board discretion that this implies are viewed critically. It therefore decided no longer to issue this remuneration component when the new remuneration system takes effect after the AGM 2022. No Restricted Share Awards were made as a result in 2024.
The Restricted Share Plan defines for each award a performance period of four consecutive calendar years in which the performance is measured. The AGM 2020 defined Adjusted EBITDA as the performance indicator. The performance indicator is measured for each year in the performance period. The performance in a given year is fixed for the remainder of the lock-up period.
To measure performance, Adjusted EBITDA is calculated for each year of the performance period and compared with the Adjusted EBITDA forecast for the financial year in the first quarter of that year. The forecast and the actual financial ratio for the previous year are published in the annual report.
The key performance indicator for the respective year is achieved when Adjusted EBITDA corresponds to or exceeds forecast Adjusted EBITDA. The minimum target is achieved when Adjusted EBITDA corresponds to or exceeds 75% of forecast Adjusted EBITDA.
If the minimum target is not achieved in a financial year, 25% of the Restricted Share Awards are forfeit. If the target is achieved in a financial year, 25% of the Restricted Share Awards are converted into subscription rights, each for one share in Evotec SE. If the minimum target is achieved exactly in a financial year, 12.5% of the Restricted Share Awards are converted into subscription rights, each for one share in Evotec SE. If the minimum target is achieved in a financial year, but not the target, between 12.5% and 25% of the Restricted Share Awards, depending on the actual target achievement, are converted into subscription rights, each for one share in Evotec SE. There is no dividend equivalent.
For the Management Board members who were granted Restricted Share Awards for the last time in 2022 the Supervisory Board defined other performance criteria, covering revenue growth by the Evotec Group, the number of partnered projects, the implementation of an ESG strategy and long-term organizational development. For competition reasons these are only published retrospectively after the performance period has come to an end.
The Restricted Share Plan 2020 works as follows:
71
The payment curve for the KPI adjusted EBITDA is as follows:
No Restricted Share Awards were granted to Management Board members in 2024 and none became exercisable. However, there are still restricted share awards issued in the past before the 2022 remuneration system comes into force, which will vest in 2025 and 2026.
Outlook for variable remuneration
Transparent and quantifiable ESG criteria were included in the variable remuneration components in the remuneration system 2022. A substantial part of the short-term annual remuneration will have to be invested in Company shares and held for three years in future, in order to better align the interests of Management Board members with those of shareholders. The performance period for the Share Performance Plan 2022 adopted by the AGM on June 22, 2022, was increased to four years and the pay-for-performance approach was strengthened. In addition, the Restricted Share Plan 2020 no longer forms part of the new remuneration system and is no longer issued to members of the Management Board now that the new system is in effect.
Other remuneration rules
Benefits promised or granted by third parties
No benefits were promised or granted to a Management Board member by any third party concerning their work as a Management Board member.
72
Penalty and claw back rules
If necessary, the Supervisory Board may withhold (penalty clause) or retract (claw back) variable remuneration components if a Management Board member is in serious breach of their obligations, particularly their compliance obligations. The current employment contracts of all Management Board members include such claw back provisions.
The Company did not make use of its right to withhold or retract variable remuneration in financial year 2024. When Dr Lanthaler left as CEO in early January 2024, however, it was agreed consensual that he would not be paid a bonus for 2023.
Severance payments
Payments to a Management Board member if the service contract is terminated prematurely, without there being an important reason for the termination, are limited to two annual salaries and may not exceed the annual remuneration for the remainder of the service contract (cap on severance pay). No payments are made to the Management Board member if the employment contract is terminated for an important reason for which the Management Board member is responsible. The annual remuneration used to calculate the severance payment is the basic salary plus target bonus.
The company made use of this in the financial year 2024 and paid a severance package of two years’ annual remuneration (€1,360,000) upon the early termination of Dr Craig Johnstone’s management contract. In addition, he retains his SPA, and restricted share awards granted until 2024 in the pro-rata amount in accordance with the plan terms.
Dr Matthias Evers did not receive any severance pay upon his departure, but in accordance with the plan terms, he retains his pro-rata SPA and restricted share awards granted up to his departure.
Change of control
To the extent that their tasks and responsibilities change as a result of the change of control, Management Board members have the exceptional right to terminate their employment contract if a shareholder or third party acquires at least 30% of the shares in Evotec SE. The termination right may be exercised, giving three months’ notice, at any time within twelve months of the change of control. At the end of the notice period the Company is no longer obliged to pay any remuneration benefits, with the exception of a one-off severance payment of 18 months’ salary for the Management Board member concerned, made up of basic pay and the monetary value of any ancillary benefits.
If a change of control takes place during the vesting period for the SPA, the allocations to all participants made as part of the Share Performance Plan 2017 are irrevocably transferred and fully settled in cash up to certain limits. In the Share Performance Plan 2022 the threshold for a change of control that triggers the irrevocable transfer and payment of the SPA was raised from 30% to >50%. It was also determined that this irrevocable transfer and settlement only takes place if the Management Board member concerned exercises their exceptional right to terminate their contract because their tasks and responsibilities have been significantly altered as a result of the change of control.
If a change of control takes place during the vesting period for the RSA, the allocations made as part of the Restricted Share Plan 2020 are settled immediately in cash when they fall due, subject to certain restrictions. The settlement amount is to be calculated based on the notional number of exercisable subscription rights and subject to the applicable cap. It should assume that the targets for the respective KPI have been achieved for those years for which no definitive assessment has been made at this time.
Non-competition clause
Non-competition clauses have been agreed with the Management Board members for the time after their departure. In return, Evotec SE will make compensation payments for a period of twelve months after the end of the employment contract, unless the company waives the non-competition clause by resolution of the Supervisory Board. Evotec SE pays compensation for twelve months after the employment contract comes to an end. The compensation payments comprise 50% of direct remuneration paid (basic salary and variable remuneration) in the year before the employment contract ended and are paid in equal monthly installments. However, any severance payments will be fully offset.
73
Maximum remuneration
The maximum remuneration defined in the remuneration system 2022 applies to all the members of the Management Board whose contract was signed or renewed before the remuneration system 2022 came into effect at the AGM 2022. The annual maximum remuneration within the meaning of Section 87a para. 1 sentence 2 no 1 AktG for contracts signed after the effective date of the remuneration system2022 is:
| Maximum remuneration +for years in which no | |
Function | RSA’s are granted (in € k) | |
CEO |
| 7,050 |
Member of the Executive Board |
| 3,400 |
The relevant cap was not exceeded in the reporting year.
Share Ownership Guideline
The remuneration system 2022 obliges the Management Board members to hold shares in Evotec SE for the duration of their appointment to the Management Board, whereby this obligation must first be met no later than five years after they were first appointed to the Management Board (“build-up phase”). The share ownership program is intended to incentivize Management Board members to increase enterprise value in the interests of shareholders. The amount to be invested depends on the gross basic salary of the respective Management Board member. The CEO undertakes to invest 300% of their gross basic salary in Evotec shares and the other ordinary Management Board members invest 100% of their respective gross basic salary.
The Management Board members reported the following shareholdings as of December 31, 2024.
|
| (thereof, restricted |
| OutstandingShares |
| Granted unvested |
| Outstanding Shares |
| Granted unvested | ||
Shares | Shares from STI Payout) | from vested SPA’s | SPA’s (total) | from vested RSA’s | RSA’s (total) | |||||||
Management Board |
|
|
|
|
|
| ||||||
Dr. Christian Wojczewski | 50,000 | — | — | — | — | — | ||||||
Aurélie Dalbiez |
| 3,500 |
| — |
| — |
| — |
| — |
| — |
Dr. Cord Dohrmann |
| 191,084 |
| 10.679 |
| — |
| 102.917 |
| — |
| 29.851 |
Dr. Craig Johnstone |
| 31,844 |
| — |
| — |
| 45.091 |
| — |
| 34.980 |
Laetitia Rouxel |
| 9,128 |
| 9.128 |
| — |
| 32.214 |
| — |
| — |
Dr. Christian Wojczewski, Laetitia Rouxel and Aurélie Dalbiez are still in the so-called build up phase.
74
Target remuneration of current Management Board members for financial year 2024
The following table shows the target remuneration of Management Board members for financial year 2024, and on a voluntary basis for financial year 2023. This comprises the agreed target remuneration for the respective financial year, of which 100% is paid if the targets are achieved. If the appointment as a member of the Management Board begins or ends during a financial year, the remuneration is stated pro rata temporis.
| Dr. Werner Lanthaler |
| Laetitia Rouxel |
| |||||||||||||||||
CEO (until 01/2024) | CFO |
| |||||||||||||||||||
2024 | 2023 | 2024 | 2023 |
| |||||||||||||||||
|
|
|
| in % |
|
| in % |
|
| in % |
|
| in % | ||||||||
in k € | Total | in k € | Total | in k € | Total | in k € | Total | ||||||||||||||
Non-performance-related remuneration |
|
| Basic salary |
| 25 | 80.6 | % | 600 | 23.6 | % | 450 | 19.9 | % | 338 | 28.3 | % | |||||
| + |
| Ancillary benefits |
| 6 |
| 19.4 | % | 141 |
| 5.5 | % | 297 |
| 13.1 | % | 71 |
| 6.0 | % | |
+ | Compensation payments | — | 0.0 | % | — | 0.0 | % | 300 | 13.3 | % | 300 | 25.1 | % | ||||||||
| = |
| Total |
| 31 |
| 100.0 | % | 741 |
| 29.2 | % | 1,047 |
| 46.3 | % | 709 |
| 59.4 | % | |
|
| Short-term, one-year |
|
|
|
|
|
|
|
| |||||||||||
Performance-related | + | remuneration (STI) | |||||||||||||||||||
Remuneration |
|
| Bonus |
| — | 0.0 | % | 600 | 23.6 | % | 484 | 21.4 | % | 484 | 40.6 | % | |||||
|
| Long-term, multi-year | |||||||||||||||||||
+ | remuneration (LTI) | ||||||||||||||||||||
|
| Restricted Share Plan 2020 |
| — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | ||||||
|
| Share Performance Plan 2017 |
| — | 0.0 | % | 1,200 | 47.2 | % | 731 | 32.3 | % | — | 0.0 | % | ||||||
| = |
| Total target remuneration |
| 31 |
| 100.0 | % | 2,541 |
| 100.0 | % | 2,262 |
| 100.0 | % | 1,193 |
| 100.0 | % | |
Dr. Christian Wojczewski | Aurélie Dalbiez |
| |||||||||||||||||||
CEO (since 07/2024) | CPO (since 06/2024) |
| |||||||||||||||||||
2024 | 2023 | 2024 | 2023 |
| |||||||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
in k € | Total | in k € | Total | in k € | Total | in k € | Total | ||||||||||||||
Non-performance-related remuneration |
|
|
| Basic salary |
| 450 | 24.2 | % | — | — | % | 244 | 33.3 | % | — | — | % | ||||
| + |
| Ancillary benefits |
| 120 |
| 6.5 | % | — |
| — | % | 75 |
| 10.2 | % | — |
| — | % | |
+ | Compensation payments | 500 | 26.9 | — | — | % | 150 | 20.5 | |||||||||||||
| = |
| Total |
| 1,070 |
| 57.6 | % | — |
| — | % | 469 |
| 64.0 | % | — |
| — | % | |
Performance-related Remuneration |
| + |
| Short-term, one-year remuneration (STI) |
| ||||||||||||||||
|
|
| Bonus |
| 788 | 42.4 | % | — | — | % | 263 | 36.0 | % | — | — | % | |||||
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
|
| Restricted Share Plan 2020 |
| — | 0.0 | % | — | — | % | — | 0.0 | % | — | — | % | |||||
|
|
| Share Performance Plan 2017 |
| — | 0.0 | % | — | — | % | — | 0.0 | % | — | — | % | |||||
| = |
| Total target remuneration | 1,858 |
| 100.0 | % | — |
| — | % | 732 |
| 100.0 | % | — |
| — | % | ||
Dr. Cord Dohrmann | Dr. Matthias Evers |
| |||||||||||||||||||
CSO | CBO (until 09/2024) |
| |||||||||||||||||||
2024 | 2023 | 2024 | 2023 |
| |||||||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
in k € | Total | in k € | Total | in k € | Total | in k € | Total | ||||||||||||||
Non-performance-related remuneration |
|
|
| Basic salary |
| 450 | 26.2 | % | 450 | 26.1 | % | 300 | 26.1 | % | 400 | 30.0 | % | ||||
| + |
| Ancillary benefits |
| 50 |
| 2.9 | % | 56 |
| 3.3 | % | 38 |
| 3.3 | % | 54 |
| 4.0 | % | |
+ | Compensation payments | — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | ||||||||
| = |
| Total |
| 500 |
| 29.2 | % | 506 |
| 29.4 | % | 338 |
| 29.4 | % | 454 |
| 34.0 | % | |
Performance-related Remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
| |||||||||
|
|
| Bonus |
| 484 |
| 28.2 | % | 484 |
| 28.1 | % | 210 |
| 18.3 | % | 280 |
| 21.0 | % | |
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
|
| Restricted Share Plan 2020 |
| — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | |
|
|
| Share Performance Plan 2017 |
| 731 |
| 42.6 | % | 731 |
| 42.5 | % | 600 |
| 52.3 | % | 600 |
| 45.0 | % | |
| = |
| Total target remuneration | 1,715 |
| 100.0 | % | 1,721 |
| 100.0 | % | 1,148 | 100.0 | % | 1,334 | 100.0 | % | ||||
75
|
| Dr.Craig Johnstone |
| Mario Polywka |
| ||||||||||||||||
COO | CEO (01-06/2024) |
| |||||||||||||||||||
2024 | 2023 | 2024 | 2023 |
| |||||||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
|
|
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total | ||||
Non-performance-related remuneration |
|
| Basic salary |
| 400 | 30.3 | % | 400 | 30.3 | % | 306 | 47.3 | % | — | — | % | |||||
| + |
| Ancillary benefits |
| 42 | 3.2 | % | 42 | 3.2 | % | 35 | 5.4 | % | — | — | % | |||||
| + |
| Compensation payments |
| — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | — | — | % | |||||
| = |
| Total |
| 442 | 33.4 | % | 442 | 33.4 | % | 341 | 52.7 | % | — | — | % | |||||
Performance-related Remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
|
|
|
|
| |||||
|
| Bonus |
| 280 | 21.2 | % | 280 | 21.2 | % | 306 | 47.3 | % | — | — | % | ||||||
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
| Restricted Share Plan 2020 |
| — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | — | — | % | ||||||
|
| Share Performance Plan 2017 |
| 600 | 45.4 | % | 600 | 45.4 | % | — | 0.0 | % | — | — | % | ||||||
| = |
| Total target remuneration |
| 1,322 |
| 100.0 | % | 1,322 |
| 100.0 | % | 647 |
| 100.0 | % | — |
| — | % | |
Remuneration awarded and owed to current Management Board members in the financial year pursuant to Section 162 AktG
The following tables show the fixed and variable remuneration components awarded and owed to the Management Board members in 2023 and 2024 in accordance with Section 162 (1) sentence 2 no. 1 AktG. Since the work for the annual bonus 2024 was completed in full in financial year 2024, it is attributed to the remuneration awarded and owed in 2024 and so included in this remuneration report. However, the Management Board has unanimously waived the annual bonus for 2024.
In addition to the amount of remuneration, the individual fixed and variable remuneration components are shown as a proportion of total remuneration in accordance with Section 162 (1) sentence 2 no. 1 AktG. The proportions are based on the remuneration components awarded and owed in the respective financial year, in accordance with Section 162 (1) sentence 1 AktG.
Dr. Werner Lanthaler |
| Laetitia Rouxel | |||||||||||||||||||
CEO (until 01/2024) |
| CFO | |||||||||||||||||||
2024 | 2023 |
| 2024 | 2023 | |||||||||||||||||
in % | in % |
| in % | in % |
| ||||||||||||||||
in k € | Total | in k € | Total |
| in k € | Total | in k € | Total |
| ||||||||||||
Non-performance-related remuneration |
|
|
| Basic remuneration for the FY |
| 25 | 81.0 | % | 600 | 30.9 | % | 450 | 25.3 | % | 338 | 37.9 | % | ||||
| + |
| Ancillary benefits for the FY |
| 6 |
| 19.0 | % | 141 |
| 7.3 | % | 297 |
| 16.7 | % | 71 |
| 8.0 | % | |
+ | Compensation payments | — | 0.0 | % | — | 0.0 | % | 300 | 16.9 | % | 300 | 33.8 | % | ||||||||
| = |
| Total |
| 31 |
| 100.0 | % | 741 |
| 38.2 | % | 1,047 |
| 58.9 | % | 709 |
| 79.7 | % | |
Performance-related remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
| |||||||||
| + |
| Bonus for the FY |
| — |
| — | % | — |
| — | % | — |
| 0.0 | % | — |
| 0.0 | % | |
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
|
| Restricted Share Plan 2020 |
| — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | |
|
|
| Share Performance Plan 2017 |
| — |
| — | % | 1,200 |
| 61.8 | % | 731 |
| 41.1 | % | 181 |
| 20.3 | % | |
| = |
| Total remuneration as defined in Sec. 162 AktG | 31 | 100.0 | % | 1,941 | 100.0 | % | 1,778 | 100.0 | % | 890 | 100.0 | % | ||||||
Dr. Christian Wojczewski | Aurélie Dalbiez |
| |||||||||||||||||||
CEO (since 07/2024) | CFO (since 06/2024) |
| |||||||||||||||||||
2024 | 2023 | 2024 | 2023 |
| |||||||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
in k € | Total | in k € | Total | in k € | Total | in k € | Total | ||||||||||||||
Non-performance-related remuneration |
|
|
| Basic remuneration for the FY |
| 450 | 42.1 | % | — | — | % | 244 | 52.0 | % | — | — | % | ||||
| + |
| Ancillary benefits for the FY |
| 120 |
| 11.2 | % | — |
| — | % | 75 |
| 16.0 | % | — |
| — | % | |
+ | Compensation payments | 500 | 46.7 | % | — | — | % | 150 | 32.0 | % | — | — | % | ||||||||
| = |
| Total |
| 1,070 |
| 100.0 | % | — |
| — | % | 469 |
| 100.0 | % | — |
| — | % | |
Performance-related remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
| |||||||||
| + |
| Bonus for the FY |
| — |
| 0.0 | % | — |
| — | % | — |
| 0.0 | % | — |
| — | % | |
| + |
| Long-term, multi-year remuneration (LTI) | — | |||||||||||||||||
|
|
| Restricted Share Plan 2020 |
| — |
| 0.0 | % | — |
| — | % | — |
| 0.0 | % | — |
| — | % | |
|
|
| Share Performance Plan 2017 |
| — |
| 0.0 | % | — |
| — | % | — |
| 0.0 | % | — |
| — | % | |
| = |
| Total remuneration as defined in Sec. 162 AktG | 1,070 | 100.0 | % | — | — | % | 469 | 100.0 | % | — | — | % | ||||||
76
Dr. Cord Dohrmann | Dr. Matthias Evers |
| |||||||||||||||||||
CSO | CBO (until 09/2024) |
| |||||||||||||||||||
| 2024 |
| 2023 |
| 2024 |
| 2023 |
| |||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total |
| |||||
Non-performance-related remuneration |
|
|
| Basic remuneration for the FY |
| 450 | 36.6 | % | 450 | 30.4 | % | 300 | 30.2 | % | 400 | 33.5 | % | ||||
| + |
| Ancillary benefits for the FY |
| 50 |
| 4.1 | % | 56 |
| 3.8 | % | 38 |
| 3.8 | % | 54 |
| 4.5 | % | |
Compensation payments | — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | — | 0.0 | % | |||||||||
| = |
| Total |
| 500 |
| 40.6 | % | 506 |
| 34.2 | % | 338 |
| 34.0 | % | 454 |
| 38.0 | % | |
Performance-related remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
|
| ||||||||
| + |
| Bonus for the FY |
| — |
| — | % | 242 |
| 16.4 | % | 57 |
| 5.7 | % | 140 |
| 11.7 | % | |
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
|
| Restricted Share Plan 2020 |
| — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | — |
| 0.0 | % | |
|
|
| Share Performance Plan 2017 |
| 731 |
| 59.4 | % | 731 |
| 49.4 | % | 600 |
| 60.3 | % | 600 |
| 50.3 | % | |
| = |
| Total remuneration as defined in Sec. 162 AktG | 1,231 |
| 100.0 | % | 1,479 |
| 100.0 | % | 995 | 100.0 | % | 1,194 | 100.0 | % | ||||
| Dr. Craig Johnstone |
| Mario Polywka |
| |||||||||||||||||
COO | CEO (01-06/2024) |
| |||||||||||||||||||
| 2024 | 2023 | 2024 | 2023 |
| ||||||||||||||||
in % | in % | in % | in % |
| |||||||||||||||||
|
|
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total |
| in k € |
| Total | ||||
Non-performance-related remuneration |
|
| Basic remuneration for the FY |
| 400 | 16.7 | % | 400 | 33.8 | % | 306 | 72.0 | % | — | — | % | |||||
| + |
| Ancillary benefits for the FY |
| 42 | 1.7 | % | 42 | 3.6 | % | 35 | 8.2 | % | — | — | % | |||||
| + |
| Compensation payments |
| 1,360 | 56.6 | % | — | 0.0 | % | — | — | % | — | — | % | |||||
| = |
| Total |
| 1,802 | 75.0 | % | 442 | 37.4 | % | 341 | 80.2 | % | — | — | % | |||||
Performance-related remuneration |
| + |
| Short-term, one-year remuneration (STI) |
|
|
|
|
|
|
|
|
|
|
|
| |||||
|
| Bonus for the FY |
| — | 0.0 | % | 140 | 11.8 | % | 84 | 19.8 | % | — | — | % | ||||||
| + |
| Long-term, multi-year remuneration (LTI) | ||||||||||||||||||
|
| Restricted Share Plan 2020 |
| — | 0.0 | % | — | 0.0 | % | — | — | % | — | — | % | ||||||
|
| Share Performance Plan 2017 |
| 600 | 25.0 | % | 600 | 50.8 | % | — | — | % | — | — | % | ||||||
| = |
| Total remuneration as defined in Sec. 162 AktG |
| 2,402 |
| 100.0 | % | 1,182 |
| 100.0 | % | 425 |
| 100.0 | % | — | — | % | ||
As in the past, Dr Craig Johnstone’s remuneration was paid by Evotec (France) SAS and covers his work on the Management Board of Evotec SE and his work as Site Head in Toulouse. As a rule, the cost of the Management Board members’ work is allocated appropriately to the Group companies.
In the financial year 2024, Dr Craig Johnstone (COO) received a severance payment of € 1,360,000, which corresponds to two times his annual compensation in line with the two-year remaining term of his Management Board contract upon departure.
Laetitia Rouxel received a sign-on bonus of € 300,000 in financial year 2023, as compensation for lost earnings and commitments to her previous employer, which was paid out in April 2023. A further tranche of the same amount was paid out in April 2024.
Dr Christian Wojczewski received a sign-on bonus of €500,000 in the financial year 2024, as compensation for lost earnings and promises made to his previous employer, which was paid out in July 2024. A further tranche of the same amount will be due for payment in July 2025.
Aurélie Dalbiez received a sign-on bonus of €150,000 in the financial year 2024, as compensation for lost earnings and promises made to her by her previous employer, which was paid out in July 2024. A further tranche of the same amount will be due for payment in July 2025.
Remuneration awarded and owed to former Management Board members in the 2024 financial year pursuant to Section 162 AktG
In the financial year 2024, Dr Matthias Evers (CBO) and Dr Craig Johnstone left the Management Board. The company paid a severance package of two years’ compensation upon the early termination of Dr Craig Johnstone’s management contract. In addition, he retains his SPA, and restricted share awards granted until 2024 in the amount of a pro-rata portion in accordance with the plan terms of a total of 45,019 Share Performance Awards and 34,980 Restricted Share Awards. Dr Matthias Evers did not receive any severance pay upon his departure, but he retains his pro-rata portion of the SPA and restricted share awards granted until his departure in accordance with the plan terms of a total of 21,497 Share Performance Awards and 39,353 Restricted Share Awards.
77
Remuneration awarded and owed to current Supervisory Board members in the 2024 financial year pursuant to Section 162 AktG
The members of the Evotec Supervisory Board are entitled to a fixed salary and the reimbursement of out-of-pocket expenses in accordance with Article 13 para 1 of Evotec SE’s Articles of Association. In accordance with the recommendations of the GCGC, the positions of Chair and Vice-Chair of the Supervisory Board and the positions of Chair or member of a committee are taken into account when setting the remuneration of the individual members. For example, following the approval of the adjusted remuneration system for the Supervisory Board by the AGM in 2022, each member of the Supervisory Board will receive fixed remuneration in the amount of €65,000. The Chair receives € 125,000 and the Vice-Chair €105,000. Members of Supervisory Board committees receive €15,000 per committee, and the committee Chair receives €30,000.
|
|
| Basic salary |
| Committee salary |
| Total remuneration | |||||
in % | in % | |||||||||||
in € | Total | in € | Total | in € | ||||||||
Prof. Dr. Iris Löw-Friedrich |
| 2024 |
| 125,000 | 80.6 | % | 30,000 | 19.4 | % | 155,000 | ||
(since 06/2014) |
| 2023 |
| 125,000 | 83.3 | % | 25,000 | 16.7 | % | 150,000 | ||
Roland Sackers |
| 2024 |
| 105,000 | 70.0 | % | 45,000 | 30.0 | % | 150,000 | ||
(since 06/2019) |
| 2023 |
| 60,000 | 63.2 | % | 35,000 | 36.8 | % | 95,000 | ||
Dr. Mario Polywka |
| 2024 |
| 2,315 | 86.7 | % | 356 | 13.3 | % | 2,671 | ||
(until 06/2024) |
| 2023 |
| 50,000 | 83.3 | % | 10,000 | 16.7 | % | 60,000 | ||
Dr. Elaine Sullivan |
| 2024 |
| 28,671 | 68.4 | % | 13,232 | 31.6 | % | 41,903 | ||
(until 06/2024) |
| 2023 |
| 50,000 | 71.4 | % | 20,000 | 28.6 | % | 70,000 | ||
Dr. Constanze Ulmer-Eilfort |
| 2024 |
| 65,000 | 59.1 | % | 45,000 | 40.9 | % | 110,000 | ||
(since 06/2021) |
| 2023 |
| 50,000 | 58.8 | % | 35,000 | 41.2 | % | 85,000 | ||
Camilla Macapili Languille |
| 2024 |
| 65,000 | 70.6 | % | 27,123 | 29.4 | % | 92,123 | ||
(since 06/2022) |
| 2023 |
| 50,000 | 83.3 | % | 10,000 | 16.7 | % | 60,000 | ||
Dr. Duncan McHale |
| 2024 |
| 36,329 | 81.2 | 8,384 | 18.8 | 44,713 | ||||
(since 06/2024) | 2023 | — | — | — | — | — | ||||||
Wesley Wheeler | 2024 | 36,329 | 81.2 | % | 8,384 | 18.8 | % | 44,713 | ||||
(since 06/2024) |
| 2023 |
| — | — | — | — | — | ||||
78
Comparison of changes in remuneration and profitability
In accordance with Section 162 (1) sentence 2 no. 2 AktG the following table shows the relative change in the remuneration awarded and owed to members of the Management Board and Supervisory Board in the financial year, compared with the average remuneration of employees on a FTE-basis, as well as selected earnings indicators for the Evotec Group.
To show the profitability of the Group the comparison includes the net income recognized in the Company’s separate financial statements, Adjusted EBITDA, and revenue of the Evotec Group, as well as the share price performance as of December 31 in each case and the relative TSR for Evotec SE.
To show the average remuneration of employees the target remuneration for all employees is used (not including apprentices, students, and interns) on a FTE- basis. This relates to the workforce of Evotec SE in Germany.
Financial year |
| 2024 |
| Change in % |
| 2023 |
| Change in % |
| 2022 |
| Change in % |
| 2021 |
| Change in % |
| 2020 |
Earnings performance |
|
|
|
|
|
|
|
|
| |||||||||
Net income for Evotec SE (HGB) in €m |
| 1.1 | 101.1 | % | (97.9) | (475.9) | % | (17.0) | * | 38.8 | % | (27.8) |
| (14.9) | % | (24.2) | ||
Adjusted EBITDA Evotec Group in €m |
| 22.6 | (66.0) | % | 66.4 | (34.7) | % | 101.7 | (5.2) | % | 107.3 | 0.6 | % | 106.7 | ||||
Revenue Evotec Group in €m |
| 797.0 | 2.0 | % | 781.4 | 4.0 | % | 751.4 | 21.6 | % | 618.0 | 23.4 | % | 500.9 | ||||
Share price Evotec SE in € |
| 8.2 |
| (57.5) | % | 19.4 |
| 20.2 | % | 16.1 |
| (61.2) | % | 41.6 |
| 55.6 | % | 26.7 |
Relative TSR of Evotec SE vs. TecDAX in % points |
| (65.9) |
| — | % | 13.4 |
| — | % | (39.7) |
| — | % | 31.8 |
| — |
| 27.1 |
Average employee remuneration (in € k) |
|
|
|
|
|
|
|
|
| |||||||||
Average remuneration |
| 67.9 |
| (12.6) | % | 77.7 |
| (0.6) | % | 78.2 |
| 5.0 | % | 74.5 |
| 5.2 | % | 70.8 |
Management Board remuneration (in € k) |
|
|
|
|
|
|
|
|
| |||||||||
Dr. Christian Wojczewski (since 07/2024) |
| 1.070 |
| — | % | — |
| — | % | — |
| — | % | — |
| — | % | — |
Aurélie Dalbiez (since 06/2024) |
| 469 |
| — | % | — |
| — | % | — |
| — | % | — |
| — | % | — |
Dr. Cord Dohrmann | 1.231 |
| (16.8) | % | 1,479 |
| 5.3 | % | 1,404 |
| (32.9) | % | 2,092 |
| 80.6 | % | 1,158 | |
Laetitia Rouxel | 1.778 |
| 99.9 | % | 890 |
| — | % | — |
| — | % | — |
| — | % | — | |
Former Management Board remuneration (in € k) |
| |||||||||||||||||
Enno Spillner (until 03/2023) | — |
| — | % | 610 |
| — | % | 1,083 |
| 20.8 | % | 897 |
| (0.5) | % | 901 | |
Dr. Werner Lanthaler (until 01/2024) | 31 | (98.4) | % | 1,941 | (22.9) | % | 2,519 | (46.0) | % | 4,661 | 130.6 | % | 2,021 | |||||
Mario Polywka (01 - 06/2024) | 425 | — | % | — | — | % | — | — | % | — | — | % | — | |||||
Dr. Matthias Evers (until 09/2024) | 995 | (16.7) | % | 1,194 | (13.7) | % | 1,384 | — | % | — | — | % | — | |||||
Dr. Craig Johnstone (until 12/2024) |
| 2.402 |
| 103.2 | % | 1,182 |
| (44.0) | % | 2,112 |
| 127.9 | % | 927 |
| (0.2) | % | 929 |
Supervisory Board remuneration (in € k) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Prof. Dr. Iris Löw-Friedrich (since 06/2014) |
| 155 |
| 3.3 | % | 150 |
| 0.0 | % | 150 |
| 31.6 | % | 114 |
| 62.9 | % | 70 |
Roland Sackers (since 06/2019) |
| 150 |
| 57.9 | % | 95 |
| (1.0) | % | 96 |
| 6.7 | % | 90 |
| 5.9 | % | 85 |
Dr. Constanze Ulmer-Eilfort (since 06/2021) |
| 110 |
| 29.4 | % | 85 |
| 16.4 | % | 73 |
| 121.2 | % | 33 |
| — | % | — |
Camilla Macapili Languille (since 06/2022) |
| 92 |
| 53.3 | % | 60 |
| 87.5 | % | 32 |
| — | % | — |
| — | % | — |
Dr. Duncan McHale (since 06/2024) |
| 45 |
| — | % | — |
| — | % | — |
| — | % | — |
| — | % | — |
Wesley Wheeler (since 06/2024) |
| 45 |
| — | % | — |
| — | % | — |
| — | % | — |
| — | % | — |
Former Supervisory Board remuneration (in € k) |
|
|
|
|
|
|
|
|
| |||||||||
Michael Shalmi (until 06/2020) |
| — |
| — | % | — |
| — | % | — |
| — | % | — |
| (100.0) | % | 27 |
Prof. Dr. Wolfgang Plischke (until 06/2021) |
| — |
| — | % | — |
| — | % | — |
| (100.0) | % | 68 |
| (54.7) | % | 150 |
Kasim Kutay (until 06/2022) |
| — |
| — | % | — |
| — | % | 28 |
| (53.3) | 60 |
| 81.8 | 33 | ||
Dr. Elaine Sullivan until 06/2024) | 41 |
| (41.4) | % | 70 |
| 7.7 | % | 65 |
| 8.3 | % | 60 |
| 0.0 | % | 60 | |
Dr. Mario Polywka (until 06/2024) | 3 |
| (95.0) | % | 60 |
| 0.0 | % | 60 |
| 9.1 | % | 55 |
| 10 | % | 50 |
*Result 2022 corrected from € (8.3) million to € (17.0) million compared to 2022 report.
Miscellaneous
Evotec has Directors and Officers (“D&O”) liability insurance for the Management Board members. This insurance policy covers the personal liability of Management Board members for any claims made against them for damages in the exercise of their duties. The insurance includes an excess or deductible for the Management Board members in accordance with the German Stock Corporation Act.
79
Additional remarks
This English report is a translation of the German original. In the event of any differences, the German version is authoritative.
| C. | Board practices. |
Supervisory Board Practices
Evotec SE has a two-tier board system consisting of Evotec’s Management Board and Evotec’s Supervisory Board. The Management Board is responsible for managing Evotec and representing the Company in its dealings with third parties, while the Supervisory Board appoints and dismisses the members of Evotec’s Management Board and oversees the management of the Company. German law prohibits the Supervisory Board from making operational management decisions. The two boards, however, work closely together to achieve long-term and sustainable growth for the Company and to grow shareholder value. They agree on the Company’s strategy and on business transactions that are significant.
Evotec’s Supervisory Board consists of six members – as provided in the current Articles of Association – all of whom are elected by the shareholders with a simple majority of the votes cast at an AGM. The proposal to the AGM is carried out in accordance with the German Corporate Governance Code’s recommendations. The six current members of Evotec’s Supervisory Board were all lastly elected at the AGM 2024. The new Supervisory Board members Dr. Duncan McHale and Wesley Wheeler have been initially elected for a term of office of two years, while the re-elected Supervisory Board members have been be elected for a three-year term of office, except for the Chairperson Prof Dr Iris Löw-Friedrich who has been re-elected for a term of office of two years to allow for a coordinated succession after reaching the maximum tenure of 12 years.
The Company provides a relevant set of on-boarding materials regarding statutory documents, policies, rules of procedures etc. for each new Supervisory Board member, which set is also accessible to each member in a virtual Board room that was set up.
The Supervisory Board appoints a chairperson and one Vice Chairperson from among its members. Prof. Dr. Iris Löw-Friedrich is elected Chairperson of the Supervisory Board, and Roland Sackers became her Vice Chairman. During 2025 the Supervisory Board will start the succession planning process for its Chairperson to allow for a coordinated succession after Prof Dr Löw-Friedrich will reach the maximum tenure of 12 years at the AGM 2026.
In accordance with the recommendations of the Code, the members of the Evotec Supervisory Board were selected regardless of their gender, nationality and age. Members are appointed according to their qualifications, professional experience, ability and independence. It should be noted, however, that the Supervisory Board has set an age limit and determined that potential candidates may not be older than 72 years of age when they are proposed for election. In addition, the Supervisory Board currently has defined two full periods of office as the regular limit for membership of the Supervisory Board. An appropriate proportion of women is also required. To this end the Supervisory Board has set a gender quota requiring a respective proportion of women and men of at least 30%.
The Supervisory Board has determined concrete objectives regarding its composition and competencies and prepared a profile of skills and expertise reflecting the company-specific situation. These objectives and skills profiles are regularly reviewed and discussed within the Supervisory Board to reflect the ongoing evolution of the Company and its further specific and unique offerings and operational activities. As a consequence, the Supervisory Board has agreed in its meeting in September 2024 on the most recent skills matrix and competency profile set out below.
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| Iris |
| Roland |
| Camilla |
| Constanze |
| Wesley |
| Duncan | |
Skills / Expertise | Löw-Friedrich | Sackers | Macapili Languille | Ulmer-Eilfort | Wheeler | McHale | ||||||
Chair; | Deputy Chair; | |||||||||||
RemCom Chair | ACC Chair | ESG Chair | ||||||||||
Independent Supervisory Board members (Chairman, ACC Chair, RemCom Chair; majority of total members |
| X1 |
| X |
| X2 |
| X |
| X |
| X |
R&D |
| X |
| — |
| — |
| — |
| — |
| X |
Biologics Manufacturing |
| — |
| — |
| X |
| — |
| X |
| — |
Biopharma |
| X |
| — |
| X |
| — |
| X |
| X |
Small Biotech |
| — |
| — |
| X |
| — |
| X |
| X |
Pharma Services |
| X |
| X |
| X |
| — |
| — |
| X |
Commercial / B2B |
| — |
| — |
| — |
| — |
| X |
| — |
M&A / Partnering |
| — |
| — |
| X |
| X |
| X |
| X |
Capital Markets |
| X |
| X |
| X |
| — |
| — |
| — |
Accounting / P&L / Risk Management |
| X |
| X3,4 |
| X4 |
| — |
| — |
| — |
Auditing & Sustainability Reporting |
| X |
| X3,4 |
| — |
| X |
| — |
| — |
Digitalization |
| X |
| X |
| — |
| — |
| — |
| — |
IT & Cybersecurity |
| — |
| X |
| — |
| — |
| — |
| — |
General Management |
| X |
| X |
| X |
| X |
| X |
| X |
Legal & Compliance |
| — |
| X |
| — |
| X |
| — |
| — |
Environment and Sustainability |
| X |
| X |
| X |
| X |
| — |
| — |
Social and HR |
| — |
| X |
| — |
| X |
| — |
| — |
Governance |
| X |
| X |
| X |
| X |
| X |
| X |
Age of Supervisory Board candidate does not exceed 72 years at time of the proposal |
| X (1960) |
| X (1968) |
| X (1983) |
| X (1962) |
| X (1956) |
| X (1966) |
Nationality |
| German |
| German |
| Canadian |
| German |
| U.S. |
| British |
Regional experience in EU / U.S. / Asia |
| EU, US, Asia |
| EU, US |
| EU, US, MENA |
| EU |
| U.S. |
| EU, US |
Female Supervisory Board member (at least 30%) |
| X |
| — |
| X |
| X |
| — |
| — |
1) Former Management Board member of UCB (until July 2024); the commercial relationship with UCB as a customer of Evotec is considered to be immaterial (approx. 0.5% of Group revenue in 2023).
2) Head of Life Sciences at Mubadala Investment Company; Mubadala Investment Company holds some 7% of the shares in Evotec, but does not exercise control within the meaning of C.9 GCGC.
3) Experience of auditing.
4) Experience of accounting.
Finally, the Supervisory Board has agreed to a rule membership of a maximum of 12 years. Overall, the Supervisory Board shall remain composed in such a way that the majority of its members are independent, including the Chairperson and Chairpersons of Audit & Compliance Committee and Remuneration & Nomination Committee and that its members as a group possess the knowledge, ability and expert experience required to properly complete its tasks.
Currently, the composition of Evotec’s Supervisory Board fulfills all those objectives: All members have an extensive international professional background from working in numerous internationally operating companies. All members are considered as independent following the two-dimensional evaluation criteria of the German Corporate Governance Code, three nationalities are represented and there are three female members. Evotec’s aspiration of “diversity of thoughts” is ensured by composing internationally experienced Management and Supervisory Boards with broad and complementary skill sets.
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The following chart provides additional diversity information about our Supervisory Board.
Board Diversity Matrix (As of December 31, 2024) | ||||
Country of Principal Executive Office | Germany | |||
Foreign Private Issuer | Yes | |||
Disclosure Prohibited Under Home Country Law | No | |||
Total Number of Members | 6 | |||
Female | Male | Non-Binary | Did Not Disclose Gender | |
Part I: Gender Identity | ||||
Directors | [3] | [3] | [0] | [0] |
Part II: Demographic Background | ||||
Underrepresented Individual in Home Country Jurisdiction | 0 | |||
LGBTQ+ | 0 | |||
Did Not Disclose Demographic Background | 6 | |||
Our Supervisory Board as a whole generally makes decisions, however decisions on certain matters may be delegated to committees of our Supervisory Board to the extent permitted by law. The chairperson, or if he or she is prevented from doing so, the vice chairperson, chairs the meetings of the Supervisory Board and determines the order in which the agenda items are discussed, the method and order of voting, as well as any adjournment of the discussion and passing of resolutions on individual agenda items after a due assessment of the circumstances. Our Supervisory Board may designate further types of actions as requiring its approval.
In addition, each member of the Supervisory Board is obliged to carry out his or her duties and responsibilities personally, and such duties and responsibilities cannot be delegated generally and permanently to third parties. However, the Supervisory Board and its committees have the right to appoint independent experts for the review and analysis of specific circumstances in accordance with its control and supervision duties under applicable European and German law. We would bear the costs for any such independent experts that are retained by the Supervisory Board or any of its committees.
Pursuant to German law, the Supervisory Board may form committees from among its members and charge them with the performance of specific tasks. The Supervisory Board determines the committees’ tasks, authorizations, and processes. Where permissible by law, important powers of the supervisory board may also be transferred to committees.
By resolution, the Supervisory Board has established an Audit and Compliance Committee, a Remuneration and Nomination Committee and an ESG Committee. Set forth in the table below are the current members of each committee. Each of the committees regularly report at the Supervisory Board meetings about recent meetings and discussions.
Name of Committee |
| Current Members as December 31, 2024 |
|
Audit and Compliance Committee | Roland Sackers, Camilla Macapili Languille, Dr. Constanze Ulmer-Eilfort | ||
Remuneration and Nomination Committee | Prof. Dr. Iris Löw-Friedrich, Roland Sackers, Wesley Wheeler | ||
ESG Committee | Dr, Constanze Ulmer-Eilfort, Dr Duncan McHale |
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Audit and Compliance Committee
Our Audit and Compliance Committee consists of Roland Sackers, Camilla Macapili Languille and Dr. Constanze Ulmer-Eilfort. Roland Sackers is the chairperson of the Audit and Compliance Committee. All members of our Audit and Compliance Committee are considered as independent pursuant to German law and pursuant to the GCGC. The Audit and Compliance Committee assists the Supervisory Board in fulfilling its independent oversight responsibilities regarding financial reporting and control. The Audit and Compliance Committee shall further oversee our compliance program to ensure that such program meets applicable legal and regulatory requirements and appropriate industry standards. The Audit and Compliance Committee has the responsibility, among others, to:
| ● | Oversee the accounting and the accounting process, the appropriateness and effectiveness of the internal control system, as it relates to financial reporting. |
| ● | Review the availability of an established and functioning risk management and reporting system and monitor our major financial risk exposure. |
| ● | Oversee the internal process for related party transactions, including approval of any related party transaction outside normal business scope and conditions. |
| ● | Monitor our compliance with legal provisions, regulations, and internal company guidelines, discuss our major compliance risks and remediation efforts, and review the compliance program and its adequacy and effectiveness. |
| ● | Monitor the internal audit activities, based on approved annual audit plans and respective reports being generated for the individual audits. |
To enable the Audit and Compliance Committee to carry out its responsibilities, it has the authority, among others, to:
| ● | Conduct a preliminary review of the annual consolidated financial statements as well as the annual statutory financial statements. |
| ● | Prepare the Supervisory Board decisions regarding whether to approve the annual consolidated financial statements as well as the annual statutory financial statements and the Supervisory Board proposal to the AGM on the election of the independent auditors for the annual consolidated financial statements as well as the annual statutory financial statements. |
| ● | After consultation with the CEO and the CFO, award the audit engagement to the independent auditors elected by the Shareholders’ Meeting. |
| ● | Discuss the quarterly statements and the half-year financial report with the Management Board and the independent auditors. |
| ● | Discuss any material changes to the auditing and accounting methods; and |
| ● | Approve contracts awarded to the independent auditors or to companies that relate to them on a legal, business, or personal basis. |
Roland Sackers and Dr. Constanze Ulmer-Eilfort qualify as “independent directors” as such term is defined in Rule 10A-3 under the Exchange Act and Nasdaq Rule 5605. Additionally, Roland Sackers qualifies as an “Audit and Compliance Committee financial expert” as that term is defined under the Exchange Act.
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Remuneration and Nomination Committee
The Remuneration and Nomination Committee consists of Prof. Dr. Iris Löw-Friedrich, Roland Sackers and Wesley Wheeler. Prof. Dr. Iris Löw-Friedrich is the chairperson of the Remuneration and Nomination Committee. The Remuneration and Nomination Committee’s duties and responsibilities to carry out its purpose include, among others:
| ● | Reviewing corporate goals and objectives for the remuneration of the members of the Management Board, including evaluation of the performance of the members of the Management Board considering these goals and making recommendations to the Supervisory Board for remuneration based on such evaluations. |
| ● | Reviewing all equity-based compensation plans and arrangements for members of the Management Board and making recommendations to the Supervisory Board regarding such plans. |
| ● | Reviewing and making recommendations to the Supervisory Board regarding service agreements and any severance arrangements or plans for members of the Management Board. |
| ● | Assisting the Supervisory Board in its oversight of the Management Board’s human resource management, including but not limited to corporate culture, diversity, and inclusion. |
| ● | Making proposals for the appointment and dismissal of members of the Management Board; and |
| ● | Identifying and screening individuals qualified to become members of the Supervisory Board. |
ESG Committee
Considering the increased importance of Environmental, Social and Governance (ESG) aspects in a corporate and global environment, Evotec’s Supervisory Board formed an ESG Committee in 2022. The ESG Committee consists of Dr. Constanze Ulmer-Eilfort, and Dr. Duncan McHale. Dr. Constanze Ulmer-Eilfort is the chairperson of the ESG Committee which is supported by the Company’s CEO, the Chief People Officer and the Head of Global Investor Relations & ESG. Together with the Management Board, the ESG Committee defines the priorities of Evotec with respect to environment, people, and governance on a rolling basis, and is advising on and monitoring the implementation of such priorities.
Management Board and Senior Management
Our Management Board consists of four members as of December 31, 2024. Our Supervisory Board determines the exact number of members of our Management Board. The Supervisory Board may also appoint a chairperson or spokesperson of the Management Board. Dr. Christian Wojczewski has been appointed chairperson of the Management Board.
Our Supervisory Board appoints the members of our Management Board for a term of up to five years. However, new members of the Management Board are appointed for a term of up to three years. They are eligible for re-appointment or extension after the completion of their term in office or at the earliest one year prior to expiration of their term in office, in each case again for up to an additional five years. Under certain circumstances, such as a serious breach of duty or a vote of no confidence by the shareholders in a shareholders’ meeting, a member of the Management Board may be dismissed with good cause prior to the completion of his or her term. Members of the Management Board have accepted no more than three supervisory board positions with other companies. Following the resignation of Dr Werner Lanthaler as Chief Executive Officer on January 3, 2024, Dr Mario Polywka was assigned from the Supervisory Board to the Management Board and appointed as interim CEO for up to twelve months. On July 1, 2024, Dr Christian Wojczewski joined Evotec as Chief Executive Officer and Chairman of the Management Board. Furthermore, Aurélie Dalbiez joined Evotec as Chief People Officer and Member of the Management Board on June 15, 2024. Dr Matthias Evers left the company with effect from September 30, 2024. Dr Craig Johnstone also left the company with effect from December 31, 2024.
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The members of our Management Board conduct the daily business of our company in accordance with applicable laws, our Articles of Association, and the rules of procedure for the Management Board adopted by our Supervisory Board. They are generally responsible for the management of our company and for handling our daily business relations with third parties, the internal organization of our business and communications with our shareholders.
A member of the Management Board of an SE governed by German law may not deal with or vote on matters relating to proposals, arrangements or contractual agreements between himself or herself and our Company, and a member of our Management Board may be liable to us if he or she has a material interest in any contractual agreement between our company and a third party which is not disclosed to and approved by our Supervisory Board.
The rules of procedure for our Management Board provide that generally the Management Board shall pass its resolutions by simple majority of the votes cast, but certain matters require a resolution of the entire Management Board, in addition to transactions for which a resolution adopted by the entire Management Board is required by law or required by our Articles of Association. The Management Board shall constitute a quorum when all members have been invited to a meeting and at least three of the five of the members including the CEO attend. Should a Chairman of the Management Board be appointed, his vote shall be decisive in the event of a parity of votes provided, however, that more than two members of the Management Board participate in passing the resolution. In case the CEO is not attending the meeting, the remaining 80% of the Management Board members shall constitute a quorum. In particular, the entire Management Board shall decide on the following matters, among others:
| ● | The budget plan for the following year, which is to be presented by the Management Board to the Supervisory Board in December of each year. |
| ● | Establishing corporate strategy, realization of organizational synergies and group objectives. |
| ● | Reporting to the Supervisory Board. |
| ● | All measures and transactions that require the Supervisory Board’s approval. |
| ● | All measures and transactions relating to a business area that is of extraordinary importance to Evotec or involving an extraordinary economic risk, including contracts outside the ordinary course of business or if the risk structure of a particular deal deviates significantly from the normal course of business more than €1,000,000. |
| ● | Taking on new lines of business or discontinuing existing lines of business. |
| ● | All global personnel related initiatives, such as Short- and Long-Term Incentive Plans. |
| ● | Investments with a total value above €3,000,000. |
| ● | Acquisitions or sales of interests or holdings and |
| ● | Certain large transactions. |
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| D. | Employees. |
As of December 31, 2024, we employed 4,827 individuals worldwide (December 31, 2023: 5,061; December 31, 2022: 4,952). In 2024, temporary employees represented 1.8% of our workforce. At the end of the reporting year, we had employees representing 88 different nationalities compared to 93 in 2023. In 2024, a total of 3,321 employees were engaged in our Shared R&D segment, 588 in the Just – Evotec Biologics segment, and 918 in sales and enabling functions.
Heads as of December 31, |
| 2024 |
| 2023 |
Austria |
| 4 | 44 | |
France |
| 1,057 | 1,056 | |
Germany |
| 1,257 | 1,319 | |
Italy |
| 876 | 926 | |
Singapore | — | 1 | ||
United Kingdom |
| 929 | 1,049 | |
United States of America |
| 704 | 666 | |
Grand Total |
| 4,827 | 5,061 |
We are committed to various environmental, social and governance initiatives, including achieving certain climate-based targets, championing diversity and inclusion and building a group-wide learning platform in connection with EVOacademy. We have a workers’ council at our Göttingen, Halle, Hamburg, Lyon, Munich, Toulouse and Verona sites, and collective bargaining agreements in place in Italy and France. None of our employees has engaged in any labor strikes or material labor disputes. We consider the relationship with employees to be positive.
| E. | Share ownership. |
The members of the Management Board and the Supervisory Board hold less than 1% of the shares issued by the Company. All shares granted unvested SPA’s and granted unvested RSA’s are listed below.
Share Ownership of Managing and Supervisory Directors’
Shares, SPA’s, RSA’s as of December 31, 2024
| (thereof, |
| ||||||||||
restricted | ||||||||||||
Shares | Out - standing |
| Granted |
| Out - standing |
| Granted | |||||
| from STI | Shares from | unvested | Shares from | unvested | |||||||
Shares | Payout) | vested SPA‘s | SPA’s (total) | vested RSA‘s | RSA’s (total) | |||||||
Management Board |
|
|
|
|
|
|
|
|
|
| ||
Dr Christian Wojczewski | 50,000 | — |
| — |
| — |
| — |
| — | ||
Enno Spillner | 64,178 |
|
| 49,946 |
|
| ||||||
Dr. Cord Dohrmann | 191,084 | 10,679 |
| — |
| 102,917 |
| — |
| 29,851 | ||
Dr. Craig Johnstone | 31,844 | — | — | 87,199 | — | 34,980 | ||||||
Aurelie Dalbiez | 3,500 | — | — | — | — | — | ||||||
Laetitia Rouxel | 9,128 | — | — | — | — | |||||||
Supervisory Board |
| |||||||||||
Prof. Dr. Iris Löw-Friedrich | 15,000 |
| — |
| — |
| — |
| — | |||
Camilla Macapili Languille |
| — |
| — |
| — |
| — | ||||
Roland Sackers |
| — |
| — | — |
| — | |||||
Wesley Wheeler | 3,188 | * |
| — |
| — |
| — |
| — | ||
Dr. Constanze Ulmer-Eilfort |
| — |
| — |
| — |
| — | ||||
Dr Duncan McHale |
| — |
| — |
| — |
| — |
*Wesley Wheeler acquired 6,375 ADRs, each representing one-half of one ordinary share, no par value per share, A detailed description of the SPA and share option plans granted to members of our Management Board and Supervisory Board can be found in the Notes (sections 2 and 21). All shares outstanding have the same voting rights.
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Performance-related variable remuneration components
In line with the principles mentioned above, the Management Board remuneration is linked to Company performance and sustainable Company growth. Under the Remuneration system 2021 that applied until the AGM 2022, the Management Board remuneration comprised both short-term, annual remuneration (“bonus”) and long-term remuneration components (Share Performance Plan 2017 and Restricted Share Plan 2020), which were approved by the AGMs in 2017 and 2022. Payments for these components depend on achieving defined financial targets. If the targets are not achieved the payment of performance-based components may be reduced to zero. If the targets are significantly outperformed, however, the amount of the payment is capped. When the new Remuneration system 2022 took effect, the link to Company performance and sustainable Company growth described above was maintained, but the Restricted Share Plan 2020 is no longer part of the long-term remuneration component. The bonus policy was also modified.
F.Disclosure of a registrants’ action to recover erroneously awarded compensation.
Not Applicable
Item 7. Major Shareholders and Related Party Transactions
| A. | Major shareholders. |
The following table presents information, as of December 31, 2024, regarding the beneficial ownership of our ordinary shares:
| ● | Each person, or group of affiliated persons, known by us to own beneficially 5% or more of our outstanding ordinary shares, |
| ● | Each member of our Supervisory Board. |
| ● | Each member of our Management Board; and |
| ● | All members of our Supervisory Board and Management Board as a group. |
The number of ordinary shares beneficially owned by each entity, person, and member of our Supervisory Board and our Management Board is determined in accordance with the rules of the SEC, and the information is not necessarily indicative of beneficial ownership for any other purpose. Under such rules, beneficial ownership includes any ordinary shares over which the individual has sole or shared voting power or investment power as well as any ordinary shares that the individual has the right to acquire within 60 days of December 31, 2024, through the exercise of any option, warrant or other right. Except as otherwise indicated, and subject to applicable community property laws, the persons named in the table have sole voting and investment power with respect to all ordinary shares held by that person.
On May 1, 2024, T. Rowe Price International Stock Fund, Baltimore, Maryland, United States of America (U.S.) disclosed pursuant to Section 33 of the Wertpapierhandelsgesetz (“WpHG”) that 9.94% of the voting rights of the Company were held as of April 29, 2024.
On October 22, 2024, T. Rowe Price International Stock Fund, Baltimore, Maryland, United States of America (U.S.) disclosed pursuant to Section 33 of the WpHG that 4.40% of the voting rights of the Company were held as of October 18, 2024.
On October 30, 2024, T. Rowe Price International Stock Fund, Baltimore, Maryland, United States of America (U.S.) disclosed pursuant to Section 33 of the WpHG that 2.98% of the voting rights of the Company were held as of October 25, 2024.
On November 7, 2024, Triton GP HoldCo SARL, Luxembourg, Luxembourg disclosed pursuant to Section 33 of the WpHG that 7.16% of the voting rights of the Company were held as of November 5, 2024.
The percentage of outstanding ordinary shares is computed based on 177,553,456 ordinary shares outstanding as of December 31, 2024, and 167,415 shares were held in treasury.
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Except as otherwise indicated in the table below, the address for each beneficial owner is Essener Bogen 7, 22419 Hamburg, Germany.
| Shares Beneficially Owned |
| |||
Name of Beneficial Owner | Number of Shares |
| Percentage of Class |
| |
5% Beneficial Owner: |
|
|
| ||
Triton GP HoldCo SARL (1) | 17,730,913 |
| 9.99 | % | |
Novo Holdings A/S (2) | 14,931,858 |
| 8.4 | % | |
Mubadala Investment Company (3) | 11,481,502 |
| 6.6 | % | |
Management Board and Supervisory Board: |
| ||||
Dr. Christian Wojczewski | 50,000 |
| * | ||
Enno Spillner | 64,178 | ||||
Aurélie Dalbiez | 3,500 | ||||
Dr. Cord Dohrmann | 191,084 |
| * | ||
Dr. Craig Johnstone | 31,844 |
| * | ||
Laetitia Rouxel | 9,128 | ||||
Prof. Dr. Iris Löw-Friedrich | 15,000 |
| — | ||
Camilla Macapili Languille | — |
| — | ||
Dr. Duncan McHale | — |
| — | ||
Wesley Wheeler | 3,188 | (4) | — | ||
Roland Sackers | — |
| — | ||
Dr. Constanze Ulmer-Eilfort | — |
| — | ||
All Management Board and Supervisory Board members as a group (12 persons) | 351,066 |
| * | ||
* Less than one percent.
| (1) | Calculated based on 177,533,384 Ordinary Shares (as defined below) registered as of June 30, 2024, as disclosed in the Issuer’s (as defined below) Current Report on Form 6-K furnished to the Securities and Exchange Commission (the “SEC”) on August 14, 2024.. |
| (2) | Consists of 14,931,858 ordinary shares held by Novo Holdings A/S, Denmark, as reported on the 13G filed with the SEC on February 14, 2024. The business address of Novo Holdings A/S is Tuborg Havnevej 19, 2900 Hellerup, Denmark. |
| (3) | Consists of 11,481,502.5 ordinary shares held by ATIC Second International Investment Company LLC, Abu Dhabi. Mubadala Investment Company PJSC (“MIC”) is wholly owned by the Government of Abu Dhabi. Investment decisions are taken independently of the Government of Abu Dhabi by the board of directors of MIC, as reported on the 13D filed with the SEC on November 16, 2021. The business address of MIC is Mamoura A Building, Muroor Street, P.O. Box 45005, Abu Dhabi, United Arab Emirates. |
| (4) | Wesley Wheeler acquired 6,375 ADR’s, each representing one-half of one ordinary share, no par value per share, |
Management is not aware of any restriction of the voting rights or the right to transfer. We are not aware of any arrangement that may, at a subsequent date, result in a change of control of our company.
Holdings by U.S. Shareholders
As of December 31, 2024, 18.75% of our outstanding ordinary shares (including shares in the form of ADSs) were held by 55 U.S. record holders.
Control of Registrant
To our knowledge, we are not directly or indirectly owned or controlled by another corporation, by any foreign government, or by any other natural or legal person.
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| B. | Related party transactions. |
For information on related party transaction see Note 32 “Related Party Transactions” of the Notes to Consolidated Financial Statements.
| C. | Interests of experts and counsel. |
Not applicable.
Item 8. Financial Information
| A. | Consolidated Statements and Other Financial Information. |
Our consolidated financial statements are appended at the end of this annual report on Form 20-F, starting at page F-1, and incorporated herein by reference.
Legal Proceedings
From time to time, we may be involved in legal proceedings in the ordinary course of business. We are currently not a party to any material legal or administrative proceedings. We are not aware of any other material legal or administrative proceedings contemplated to be brought against us. Regardless of outcome, litigation may have an adverse impact on our operations because of defense and settlement costs, diversion of management resources and other factors.
Dividend Policy
We have never paid or declared any cash dividends on our ordinary shares, and we do not anticipate paying any cash dividends on our ordinary shares soon. We intend to retain all available funds and any future earnings and reinvest them in the company’s further growth strategy to better leverage long- term growth and sustainability. All the shares represented by the ADSs generally have the same dividend rights as all our other outstanding shares.
| B. | Significant Changes. |
A detailed description of the significant changes can be found in the Notes (section 2).
Item 9. The Offer and Listing.
A. | Offer and listing details. |
Our ordinary shares are traded on the Prime Standard of the Frankfurt Stock Exchange under the symbol “EVT”. Our ADSs are listed on the Nasdaq Global Select Market under the symbol “EVO.”
B. | Plan of distribution. |
Not applicable.
C. | Markets. |
For a description of our publicly traded common shares, see “Item 9. The Offering and Listing - A. Offer and Listing Details.”
D. | Selling shareholders. |
Not applicable.
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E. | Dilution. |
Not applicable.
F. | Expenses of the issue. |
Not applicable.
Item 10. Additional Information.
| A. | Share capital. |
Not applicable.
| B. | Memorandum and articles of association. |
The information set forth in our Registration Statement on F-1 (File No. 333-260143), effective upon the closing of our initial public offering originally filed with the SEC on October 8, 2021, under the heading DESCRIPTION OF SHARE CAPITAL AND ARTICLES OF ASSOCIATION (SATZUNG) is incorporated herein by reference and updated as follows:
Share Capital
As of December 31, 2024 we have share capital, part of which is yet to be registered in the commercial register (Handelsregister), in the amount of €177,553,456.00, which is divided into 177,553,456 no-par value bearer shares (Inhaberaktien). All shares are shares with no par value (Stückaktien ohne Nennbetrag) with a notional amount attributable to each ordinary share of €1.00. Each issued ordinary share is fully paid.
Changes in Our Share Capital During the Last Fiscal Years
Since January 1, 2024, and until December 31, 2024 our share capital has changed as follows:
| ● | Due to the utilization of our conditional capital created by resolutions on June 14, 2017, our share capital as registered with the commercial register (Handelsregister) was increased in our fiscal year 2023 by issuing a total of 233,083 shares. |
| ● | By resolution of the AGM on June 22, 2022, the Company’s Management Board was authorized until June 21, 2025, subject to Supervisory Board consent, to increase the Company’s share capital by up to € 35,321,639.00 by issuing a total of up to 35,321,639 new no-par value ordinary bearer shares against cash capital contributions and/or non-cash capital contributions on one or more occasions (Authorized Capital 2022). |
| ● | With the cancellation of the existing authorization of the Management Board regarding the Authorized Capital 2022 the AGM 2024 authorized the Management Board, with the approval of the Supervisory Board, until June 9, 2029 to increase the Company’s share capital by up to € 35.437.147.00 by issuing a total of up to 35.437.147.00 new no-par-value ordinary bearer shares against cash capital contributions and/or non-cash capital contributions on one or more occasions. |
| ● | Accordingly, the Company’s share capital is increased contingently by up to € 35,437.147.00 by the issue of up to 35,437,147 new ordinary no par bearer shares, with each share representing € 1.00 of share capital. The contingent capital increase serves to grant bearer shares to holders or creditors of convertible bonds and/or warrant-linked bonds and/or profit-linked bonds (or combinations of these instruments) that are issued for subscription in cash by Evotec SE or its direct or indirect invested companies on the basis of the authorization passed by the AGM 2024 under agenda item 6, and include a conversion right, a warrant or a conversion obligation for new bearer Company shares. |
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Future Changes to the Share Capital
Authorized Capital
Under the relevant law, the general meeting of a European stock corporation (Societas Europaea) governed by German law can authorize the Management Board, with the consent of the Supervisory Board, to issue shares in a specified aggregate nominal amount of up to 50% of the issued share capital of such company at the time the resolution becomes effective. The shareholders’ authorization becomes effective upon registration in the commercial register (Handelsregister) and may extend for a period of no more than five years thereafter. Under § 5(5) of our Articles of Association (Satzung), the Management Board is authorized to increase our share capital, on one or more occasions, by a total of up to €35,321,639 by issuing, on one or more occasions, up to 35,321,639 new bearer shares with no par value (Genehmigtes Kapital), in each case with consent of the Supervisory Board. This authorization expires on June 21, 2025.
Conditional Capital
Pursuant to § 5(6) of our Articles of Association (Satzung), our share capital is conditionally increased by up to €1,200,000.00 through the issuance of new, bearer shares with no par value. The conditional capital may only be used to the extent that holders of subscription rights in the form of RSA based on the Restricted Share Plan 2020 make use of their right to subscribe for new shares in the Company. In 2024, no conditional capital pursuant to § 5(6) of our Articles of Association (Satzung) was used.
Pursuant to § 5(7) of our Articles of Association (Satzung), our share capital is conditionally increased by up to €6,000,000.00 through the issuance of new, bearer shares with no par value. The conditional capital may only be used to the extent that holders of subscription rights in the form of SPAs based on the Share Performance Plan 2022 make use of their right to subscribe for new shares in the Company. In 2024, no conditional capital pursuant to § 5(7) of our Articles of Association (Satzung) was used.
Pursuant to § 5(10) of our Articles of Association (Satzung), our share capital is conditionally increased by up to € 35,390,530.00 through the issuance of new, bearer shares with no par value. The conditional capital may only be used to issue shares to the owners or creditors of convertible bonds and/or warrant-linked bonds, participation rights and/or income bonds (or a combination of such instruments) that grant a conversion or option right to new no par value shares or designate a conversion obligation against cash contribution, issued by us or our directly or indirectly associated companies. In 2024, no conditional capital pursuant to § 5(10) of our Articles of Association (Satzung) was used.
Pursuant to § 5(11) of our Articles of Association (Satzung), our share capital is conditionally increased by up to €378,224.00 through the issuance of new, bearer shares with no par value. The conditional capital may only be used to the extent holders of subscription rights in the form of SPA based on the Share Performance Plan 2015 make use of their right to subscribe for new shares in the Company. In 2024, no conditional capital pursuant to § 5(11) of our Articles of Association (Satzung) was used.
Pursuant to § 5(12) of our Articles of Association (Satzung) our share capital is conditionally increased by up to € 4,962,269.00 through issuance of new, bearer shares with no par value. The conditional capital may only be used to the extent holders of subscription rights in the form of SPA based on the Share Performance Plan 2017 make use of their right to subscribe for new shares in the Company.
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Preemptive Rights
Accordingly, under our Articles of Association (Satzung), the Management Board may, with the consent of the Supervisory Board, exclude such preemptive rights in a capital increase from the authorized capital:
| ● | to the extent that the new shares are issued in return for cash contributions and the proportional share of the share capital that applies to the shares to be newly issued does not in the aggregate exceed the amount of a total of €17,660,819.00 or, should this amount be lower, of a total of 10% of the share capital existing at the time of effectiveness and at the time of the first exercise of this authorization for precluded subscriptions, and the issue price of the new shares is not significantly below the market price of the existing listed shares of the Company at the time of the final determination of the issue price; |
| C. | Material contracts. |
We have not entered into any material contracts other than in the ordinary course of business and other than those described in “Item 4. Business Overview” or “Item 5. Operating and Financial Review and Prospects” or elsewhere in this annual report (including the Exhibits).
| D. | Exchange controls. |
There are currently no legal restrictions in the Federal Republic of Germany on international capital movements and foreign exchange transactions, except in limited embargo circumstances and connection with economic sanctions restrictions relating to certain areas, entities or persons because of applicable resolutions adopted by the United Nations and regulations and other legal provisions adopted by the EU.
For statistical purposes, there are, however, reporting duties regarding transactions involving cross- border monetary transfers. With some exceptions, every corporation or individual residing in the Federal Republic of Germany must report to the German Central Bank (Deutsche Bundesbank) within a certain period of time (i) any payment received from, or made to, a non-resident corporation or individual, or for the account of such person, that exceeds €12,500 (or the equivalent in a foreign currency) and (ii) in case the sum of claims against, or liabilities payable to, non-residents or corporations exceeds €5,000,000 (or the equivalent in a foreign currency) at the end of any calendar month. Payments include cash payments made by means of direct debit, checks, and bills, remittances denominated in euros and other currencies made through financial institutions, netting, and clearing arrangements, as well as bringing in property and rights into a corporation, branch office or production site. Not included are payments made for the import and export of goods as well as payments made for the processing of loans. Infringements of these reporting duties can be fined as an administrative offense.
| E. | Taxation. |
German Taxation of Holders of ADSs
The following discussion addresses certain German tax consequences of acquiring, owning, or disposing of the ADSs. Except for “—Taxation of Holders Tax Resident in Germany” below, which provides an overview of dividend taxation and of capital gains taxation with respect to holders that are residents of Germany, this discussion applies only to U.S. treaty beneficiaries (defined below) that hold our ADSs.
This discussion is based on domestic German tax laws, including, but not limited to, circulars issued by German tax authorities, which, for example, are not binding on the German courts, and the Treaty (defined below). It is based upon tax laws in effect at the time of filing of this annual report. These laws are subject to change, possibly with retroactive effect. For example, certain member states of the EU are considering introducing a financial transaction tax (Finanztransaktionssteuer) which, when introduced, may also be applicable on sales and/or transfer of ADSs. There is no assurance that German tax authorities will not challenge one or more of the tax consequences described in this discussion.
In addition, this discussion is based upon the assumption that each obligation in the deposit agreement and any related agreement will be performed in accordance with its terms. It does not purport to be a comprehensive or exhaustive description of all German tax considerations that may be of relevance in the context of acquiring, owning, and disposing of ADSs.
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The tax information presented in this annual report is not a substitute for tax advice. Prospective holders of ADSs should consult their own tax advisors regarding the German tax consequences of the purchase, ownership, disposition, donation, or inheritance of ADSs considering their circumstances, including the effect of any state, local, or other foreign or domestic laws or changes in tax law or interpretation. The same applies with respect to the rules governing the refund of any German dividend and capital gain withholding tax (Kapitalertragsteuer) withheld. Only an individual tax consultation can appropriately account for the tax situation of each investor.
General
Based on the circular issued by the German Federal Ministry of Finance (BMF-Schreiben), dated May 24, 2013, reference number IV C 1-S2204/12/10003, as amended by the circular dated December 18, 2018 (reference number IV C 1 – S 2204/12/10003), in respect of the taxation of American Depositary Receipts, or ADRs, on domestic shares, or the ADR Tax Circular, for German tax purposes, the ADSs should represent a beneficial ownership interest in the underlying shares of Evotec and qualify as ADRs for the purpose of the ADR Tax Circular. If the ADSs qualify as ADRs under the ADR Tax Circular, dividends will accordingly be attributable to holders of the ADSs for German tax purposes, and not to the legal owner of the ordinary shares (i.e., the financial institution on behalf of which the ordinary shares are deposited at a domestic depository for the ADS holders).
Furthermore, holders of the ADSs should, considering the ADR Tax Circular, be treated as beneficial owners of the capital of Evotec with respect to capital gains (see below in section “—German Taxation of Capital Gains of the U.S. Treaty Beneficiaries of the ADSs”). However, investors should note that circulars published by the German tax authorities (including the ADR Tax Circular) are not binding on German courts, including German tax courts, and it is unclear whether a German court would follow the ADR Tax Circular in determining the German tax treatment of the ADSs.
Taxation of Holders Not Tax Resident in Germany
The following discussion describes selected German tax consequences of acquiring the ADSs, owning the ADSs and disposing of the ADSs for a holder that is a U.S. treaty beneficiary (defined below). For purposes of this discussion, a “U.S. treaty beneficiary” is a resident of the United States for purposes of the Convention between the Federal Republic of Germany and United States of America for the Avoidance of Double Taxation and the Prevention of Fiscal Evasion with respect to Taxes on Income and on Capital and Certain Other Taxes of 1989, as amended by the Protocol as of June 1, 2006 (Abkommen zwischen der Bundesrepublik Deutschland und den Vereinigten Staaten von Amerika zur Vermeidung der Doppelbesteuerung und zur Verhinderung der Steuerverkürzung auf dem Gebiet der Steuern vom Einkommen und vom Vermögen und einiger anderer Steuern in der Fassung vom 1. Juni 2006) hereinafter referred to as the “Treaty,” who is eligible for relevant benefits under the Treaty.
A holder will be a U.S. treaty beneficiary entitled to full Treaty benefits in respect of the ADSs if it is, inter alia:
| ● | The beneficial owner of the ADSs (and the dividends paid with respect thereto). |
| ● | A U.S. tax resident corporation or individual. |
| ● | Not also a resident of Germany for German tax purposes; and |
| ● | Not subject to the limitation on benefits (i.e., anti-treaty shopping) article of the Treaty that applies in limited circumstances. |
Special rules apply to pension funds and certain other tax-exempt investors.
This discussion does not address the treatment of ADSs that are (i) held in connection with a permanent establishment or fixed base through which a U.S. treaty beneficiary carries on business or performs personal services in Germany or (ii) part of business assets for which a permanent representative in Germany has been appointed.
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General Rules for the Taxation of Holders Not Tax Resident in Germany
Non-German resident holders of ADSs are subject to German taxation with respect to German source income (beschränkte Steuerpflicht). Dividends distributed by stock corporations having their registered seat or place of management in Germany qualify as German source income.
According to the ADR Tax Circular, income from the shares should be attributed to the holder of the ADSs for German tax purposes. Consequently, income from the ADSs should be treated as German source income. This only applies in general to dividend income as capital gains in case of ownership below 1% are generally not German source income.
The capital gains from the disposition of the ADSs realized by a non-German resident holder which does not maintain a permanent establishment or other taxable presence in Germany would be treated as German source income and be subject to German tax if the ADSs qualify as a Qualifying Participation. A “Qualifying Participation” exists if a holder at any time during the five years preceding the disposition, directly or indirectly, owned at least 1% or more of Evotec’s share capital, irrespective of whether through the ADSs or shares of Evotec. If such holder had acquired the ADSs without consideration, the previous owner’s holding period and quota would generally be considered.
Dividend payments, to the extent funded from Evotec’s tax-recognized contribution account (steuerliches Einlagekonto), do not, subject to certain prerequisites, form part of the taxable dividend income but should lower the holder’s acquisition costs for the ADSs.
German Withholding Taxation of Dividends of the U.S. Treaty Beneficiaries of the ADSs
Generally, the full amount of a dividend distributed by Evotec to a non-German resident holder which does not maintain a permanent establishment or other taxable presence in Germany is subject to (final) German withholding tax at an aggregate rate of 26.375% (that amount consists of 25% on dividends distributed plus solidarity surcharge of 5.5% thereon). The basis for the withholding tax is generally the dividend approved for distribution by our general shareholders’ meeting. German withholding tax is withheld and remitted to the German tax authorities by (i) the disbursing agent (i.e., the German credit institution, financial services institution or securities institution) and in each case including a German branch of a foreign enterprise, but excluding a foreign branch of a German enterprise)) that holds or administers the underlying shares in custody and (a) disburses or credits the dividend income from the underlying shares, (b) disburses or credits the dividend income from the underlying shares on delivery of the dividend coupons or (c) disburses such dividend income to a foreign agent; (ii) the central securities depository (Wertpapiersammelbank) holding the underlying shares in collective safe custody, if such central securities depository disburses the dividend income from the underlying shares to a foreign agent, or (iii) the Company itself if and to the extent shares held in collective custody (Sammelverwahrung) by the central securities depository (Wertpapiersammelbank) are treated as so-called “abgesetzte Bestände” (stock being held separately), in each case regardless of whether a holder must report the dividend for tax purposes and regardless of whether or not a holder is a resident of Germany.
Pursuant to the Treaty, the German withholding tax may generally not exceed (i) 15% of the gross amount of the dividends received by a U.S. treaty beneficiary other than a company holding ADSs which represent 10% or more of the voting shares in Evotec, and (ii) 5% of the gross amount of the dividends received by a U.S. treaty beneficiary that is a company holding ADSs which represent 10% or more of the voting shares in Evotec. The excess of the total withholding tax, including the solidarity surcharge, over the maximum rate of withholding tax permitted by the Treaty is refunded to U.S. treaty beneficiaries upon application. For example, for a declared dividend of 100, a U.S. treaty beneficiary initially receives 73.625 (100 minus the 26.375% withholding tax including solidarity surcharge). A U.S. treaty beneficiary other than a company holding ADSs which represent 10% or more of the voting shares in Evotec is generally entitled to a partial refund from the German tax authorities in the amount of 11.375% of the gross dividend (of 100). As a result, the U.S. treaty beneficiary should generally ultimately receive 85 (85% of the declared dividend) following the refund of the excess withholding.
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However, it should be noted that there is uncertainty as to how the German tax authorities will apply the refund process to dividends on the ADSs with respect to non-German resident holders. There may be a more detailed scrutiny with respect to ADSs because some fraudulent cases involving ADSs came to the attention of the German tax authorities in fall 2018. In those cases, owners of ADSs requested tax refunds although there were no underlying shares with respect to these ADSs. Therefore, it also cannot be excluded that the tax authorities want to treat ADSs differently in the future. The German Federal Ministry of Finance issued a circular (BMF-Schreiben), dated December 18, 2018, reference number IV C 1 —S 2204/12/10003, to address such fraudulent tax refund requests. The circular mandates that the issuance of a tax certificate (Steuerbescheinigung), a prerequisite to claim German withholding tax relief, requires the depository agent (Hinterlegungsstelle) to confirm that only ADSs were issued for which underlying shares were deposited with the depository agent at the issuances of the ADSs. This circular may result in a double withholding on dividends paid in the case the ADSs are being held by a non-tax resident or by a German tax resident in an account with a German (custody) bank (because the circular prohibits the issuance of so called “collective tax certificates” (“Sammelsteuerbescheinigungen”) which are generally the requirement to refrain from the “second withholding”), i.e. in such case the ADS Holders would need to request two tax certificates (Steuerbescheinigungen) in order to be able to fully reclaim (or credit) the tax withheld on the “second withholding”. Further, such refund is subject to the German anti-treaty-shopping rule (as described below in “— Withholding Tax Refund for U.S. Treaty Beneficiaries”).
German Withholding Taxation of Capital Gains of the U.S. Treaty Beneficiaries of the ADSs
Pursuant to the Treaty, capital gains from the disposal of a Qualifying Participation realized by a U.S. treaty beneficiary are, however, generally exempt from German taxation. Pursuant to the Treaty, U.S. treaty beneficiaries are not subject to German tax in relation to capital gains from the disposal of a Qualifying Participation even under the circumstances described in the preceding paragraph and therefore should not be subject to German taxation on capital gains from the disposition of the ADSs.
German statutory law practically requires the disbursing agent to levy withholding tax on capital gains from the sale of ADSs or other securities held in a custodial account in Germany. With regard to the German taxation of capital gains, disbursing agent generally means a German credit institution, financial services institution, securities trading enterprise or securities trading bank (in each case including a German branch of a foreign enterprise, but excluding a foreign branch of a German enterprise) that holds the ADSs in custody or administers the ADSs for the holder or conducts sales or other dispositions and disburses or credits the income from the disposal of the ADSs to the holder of the ADSs. The German statutory law does not explicitly condition the obligation to withhold taxes on capital gains being subject to taxation in Germany under German statutory law or on an applicable income tax treaty permitting Germany to tax such capital gains.
However, a circular issued by the German Federal Ministry of Finance, dated May 19, 2022, reference number IV C 1 - S 2252/19/10003 :009, as most recently amended by a circular dated December 20, 2022, IV C 1 - S 2252/19/10003 :011, provides that taxes need not be withheld when the holder of the custody account is not a resident of Germany for tax purposes and the income is not subject to German taxation. The circular further states that there is no obligation to withhold such tax even if the non-resident holder owns at least 1% of the share capital of a German corporation. Pursuant to German statutory law, the entity responsible for levying withholding tax (such as the disbursing agent) must take circulars issued by the German tax authorities which are published in the German Federal Tax Gazette (Bundessteuerblatt) (such as the circular mentioned above) into account when imposing withholding tax, so that in practice, the disbursing agents typically comply with the guidance mentioned above.
Therefore, a disbursing agent would only withhold tax at 26.375% on capital gains derived by a U.S. treaty beneficiary from the sale of ADSs held in a custodial account in Germany if the disbursing agent did not follow the abovementioned guidance. In this case, the U.S. treaty beneficiary may be entitled to claim a refund of the withholding tax from the German tax authorities under the Treaty, as described below in “—Withholding Tax Refund for U.S. Treaty Beneficiaries.” Claim a refund of taxes withheld on capital gains from the disposition of the ADSs, which do not qualify as Qualifying Participations or for which a statutory withholding tax requirement does not exist, may also base on German statutory domestic law.
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Withholding Tax Refund for U.S. Treaty Beneficiaries
U.S. treaty beneficiaries are generally eligible for treaty benefits under the Treaty, as described above in “—Taxation of Holders Not Tax Resident in Germany.” Accordingly, U.S. treaty beneficiaries are in general entitled to claim a refund of (i) the portion of the otherwise applicable 26.375% German withholding tax (Kapitalertragsteuer) on dividends that exceeds the applicable Treaty rate and (ii) the full amount of German withholding tax (Kapitalertragsteuer) on capital gains from the disposition of ADSs. The application for such claim is generally to be filed with the Federal Central Office of Taxation (Bundeszentralamt für Steuern) within four years after the end of the calendar year in which the capital gains or dividends have been received (bezogen) and, among other things, requires that a withholding tax certificate documenting the imposed German withholding tax is provided by the U.S. treaty beneficiary. Under the Withholding Tax Relief Modernization Act (Abzugsteuerentlastungsmodernisierungsgesetz) which was passed into law on June 9, 2021, the withholding tax certificate will be replaced for dividend income (including under ADRs) accruing after December 31, 2024, by a notification to be submitted by the disbursing agent directly to the Federal Central Tax Office upon request of the holder. In particular regarding ADRs, the disbursing agent will be required to include substantial additional information in the notification and will have to obtain certain confirmations from the issuer of the ADRs and will only be allowed to submit the notification (which will be a pre-requisite for any refund) to the Federal Central Tax Office once it has collected all information and confirmations.
However, in respect of dividends, the refund described in the preceding paragraph is only possible if, due to special rules on the restriction of withholding tax credit, the following three cumulative requirements are met: (i) the holder must qualify as beneficial owner of the ADSs for an uninterrupted minimum holding period of 45 days within a period starting 45 days prior to and ending 45 days after the due date of the dividends, (ii) the holder has to bear at least 70% of the change in value risk related to the ADSs during the minimum holding period as described under (i) of this paragraph and has not entered into (acting by itself or through a related party) hedging transactions which lower the change in value risk by more than 30%, and (iii) the holder must not be obliged to fully or largely compensate directly or indirectly the dividends to third parties. If these requirements are not met, then for a holder not being tax-resident in Germany who applied for a full or partial refund of the withholding tax pursuant to a double taxation treaty, no refund is available. This restriction generally does only apply if (a) the tax underlying the refund application is below a tax rate of 15% based on the gross amount of the dividends and (b) the holder does not directly own 10% or more of the shares of Evotec and is subject to income taxes in its state of residence, without being tax-exempt. The restriction of the withholding tax credit does not apply if the holder has beneficially owned the ADSs for at least one uninterrupted year prior to receipt (Zufluss) of the dividends. In addition to the restrictions, in particular, pursuant to a circular issued by the German Federal Ministry of Finance, dated July 9, 2021, reference number IV C 1-S 2252/19/10035:014, the withholding tax credit may also be denied as an anti-abuse measure.
In general, investors should note that it is unclear how the German tax administration will apply the refund process to dividends on the ADSs. Further, such refund is subject to the German anti-treaty shopping rule which has been reformed by the Withholding Tax Relief Modernization Act (Abzugsteuerentlastungsmodernisierungsgesetz) dated June 2, 2021. Under the reformed German anti-treaty shopping rule, a foreign company has no right to a refund of German withholding tax with regard to income accruing after June 8, 2021 to the extent (i) persons holding ownership interests in the foreign company would not be entitled to the refund if they derived the income (i.e. the dividend distributed by Evotec) directly and (ii) the source of the income does not have a substantial connection to the business activities of the foreign company. The mere generation of the income by the foreign company, passing the income on to the persons holding ownership interests in the foreign company and any activity of the foreign company which is conducted by a business organization that is not appropriate for the business purpose, do not qualify as a business activity within the meaning of the preceding sentence. However, the German anti-treaty shopping rule shall not apply (i) to the extent the foreign company demonstrates that none of the main purposes of its interposition was to obtain a tax advantage or (ii) if the foreign company’s principal class of stock is regularly traded in substantial volume on a recognized stock exchange. Whether or not and to which extent the anti-treaty shopping rule applies to the ADSs must be analyzed on a case-by-case basis considering all relevant tests. In addition, the interpretation of these tests is disputed and to date no published decisions of the German Federal Tax Court exist in this regard.
Due to the legal structure of the ADSs, only limited guidance from the German tax authorities exists on the practical application of the refund process with respect to the ADSs and the respective limitations. According to the current ADR Tax Circular, for ADR programs (which are considered comparable to ADS programs) a collective tax certificate in connection with a withholding of tax amounts may no longer be issued by the domestic depositary of the shares upon request of the foreign depositary agents. Rather, individual tax certificates need to be issued which might delay a potential refund procedure. Moreover, the simplified refund procedure based on electronic data exchange (Datenträgerverfahren) for claims for reimbursement based on ADRs is currently not applied by the tax authorities.
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Taxation of Holders Tax Resident in Germany
This subsection provides an overview of dividend taxation and of capital gains taxation regarding the general principles applicable to ADS holders that are tax resident in Germany. A holder is a German tax resident if, in case of an individual, he or she maintains a domicile (Wohnsitz) or a usual residence (gewöhnlicher Aufenthalt) in Germany or if, in case of a corporation, and it has its place of management (Geschäftsleitung) or registered seat (Sitz) in Germany.
The German dividend and capital gains taxation rules applicable to German tax residents require a distinction between ADSs held as private assets (Privatvermögen) and ADSs held as business assets (Betriebsvermögen).
ADSs as Private Assets (Privatvermögen)
If the ADSs are held as private assets by a German tax resident, dividends and capital gains (other than capital gains from the disposition of a Qualifying Participation) are taxed as investment income and are principally subject to 25% German flat income tax on capital income (Abgeltungsteuer) (plus a 5.5% solidarity surcharge (Solidaritätszuschlag) thereon, resulting in an aggregate rate of 26.375%), which is levied in the form of withholding tax (Kapitalertragsteuer). In other words, once deducted, the holder’s income tax liability on the dividends will be settled. Dividend payments to the extent funded from Evotec’s tax-recognized contribution account (steuerliches Einlagekonto), do not, subject to certain prerequisites, form part of the taxable dividend income but should lower the holder’s acquisition costs for the ADSs.
Holders of ADSs may apply to have their capital investment income assessed in accordance with the general rules and with an individual’s personal income tax rate if this would result in a lower tax burden. The holder would be taxed on gross personal investment income (including dividends or gains with respect to ADSs), less the saver’s allowance of €1,000 for an individual or €2,000 for a married couple and a registered civil union (eingetragene Lebenspartnerschaft) filing taxes jointly. The deduction of expenses related to the investment income (including dividends or gains with respect to ADSs) is generally not possible for private investors.
Losses resulting from the disposal of ADSs can only be offset against capital gains from the sale of any shares (Aktien) and other ADSs. If, however, a holder holds a Qualifying Participation, 60% of any capital gains resulting from the sale and transfer are taxable at the holder’s personal income tax rate (plus solidarity surcharge of up to 5.5% thereon). Conversely, 60% of any capital losses are recognized for tax purposes.
Since 2021, the basis for the calculation of the solidarity surcharge (Solidaritätszuschlag) has been reduced for certain individuals being subject to tax assessments (other than withholding taxes), and in certain cases, the solidarity surcharge has been eliminated for individuals. However, the elimination or reduction of the solidarity surcharge will not affect withholding taxes. Solidarity surcharge will still be levied at 5.5% on the full withholding tax amount and withheld accordingly. There will also not be any separate refund of such withheld solidarity surcharge in case the withholding tax cannot be refunded.
If applicable, church tax (Kirchensteuer) generally must be withheld from income generated by ADSs held by individuals based on an automatic data access procedure, unless the holder of ADSs has filed a blocking notice (Sperrvermerk) with the Federal Central Tax Office. The application of church tax (Kirchensteuer) reduces the aggregate rate of German flat income tax on capital income and the solidarity surcharge (Solidaritätszuschlag) thereon from 26.375% to typically approximately 25.79% or approximately 25.86% (thus resulting in an overall tax rate of approximately 27.82% or approximately 28%). Where church tax is not levied by way of withholding, it is determined by means of income tax assessment.
ADSs as Business Assets (Betriebsvermögen)
In case the ADSs are held as business assets, the taxation depends on the legal form of the holder (i.e., whether the holder is a corporation or an individual).
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Irrespective of the legal form of the holder, dividends are in principle subject to the aggregate withholding tax rate of 26.375%. The withholding tax is generally creditable in an amount of 25% of the gross dividend against the respective holder’s corporate income tax or income tax liability and in an amount of 1.375% of the gross dividend against the respective holder’s solidarity surcharge (Solidaritätszuschlag) liability. Due to special rules on the restriction of withholding tax credits in respect of dividends, a full withholding tax credit requires that the following three cumulative requirements are met: (i) the holder must qualify as beneficial owner of the ADSs for an uninterrupted minimum holding period of 45 days occurring within a period starting 45 days prior to and ending 45 days after the due date of the dividends, (ii) the holder has to bear at least 70% of the change in value risk related to the ADSs during the minimum holding period as described under (i) of this paragraph and has not entered into (acting by itself or through a related party) hedging transactions which lower the change in value risk for more than 30%, and (iii) the holder must not be obliged to fully or largely compensate directly or indirectly the dividends to other persons. Technically these special rules on the restrictions of withholding tax credits may also be applied with respect to ADSs held as private assets by German tax residents, however practically these special rules should generally not be applied pursuant to a circular issued by the German Federal Ministry of Finance, dated April 3, 2017, reference number IV C 1 – S 2299/16/10002, m.no. 131. If these requirements are not met cumulatively, three-fifths of the withholding tax imposed on the dividends must not be credited against the holder’s corporate income tax or income tax liability, but may be deducted, upon application, from the holder’s tax base for the relevant tax assessment period. A holder that is generally subject to German income tax or corporate income tax and that has received gross dividends without any deduction of withholding tax due to a tax exemption without qualifying for a full tax credit under the aforementioned requirements has to notify the competent local tax office accordingly, has to file withholding tax returns for a withholding tax of 15% in accordance with statutory formal requirements and has to make a payment in the amount of the omitted withholding tax deduction. The special rules on the restriction of withholding tax credit (and the corresponding notification and payment obligations) do not apply to a holder whose overall dividend earnings within an assessment period do not exceed €20,000 or that has been the beneficial owner of the ADSs for at least one uninterrupted year until receipt (Zufluss) of the dividends. In addition to the restrictions, in particular, pursuant to a circular issued by the German Federal Ministry of Finance, dated July 9, 2021, reference number IV C 1-S 2252/19/10035:014, as amended, the withholding tax credit may also be denied as an anti-abuse measure.
To the extent, the amount withheld exceeds the income tax liability; the withholding tax will be refunded, if certain requirements are met (including the requirements).
Special rules apply to credit institutions (Kreditinstitute), financial services institutions (Finanzdienstleistungsinstitute), financial enterprises (Finanzunternehmen), life insurance and health insurance companies, and pension funds.
In principle, dividends that a corporation receives from German or foreign corporations are subject to corporate income tax (and solidarity surcharge thereon) at a rate of 15.825% and subject to trade tax of approximately 7.0% to 21.0% depending on the multiplier applied by the relevant municipality. However, regarding holders in the legal form of a corporation, capital gains are in general effectively 95% tax exempt from corporate income tax (including solidarity surcharge). Dividends are also generally 95% tax exempt from corporate income tax (including solidarity surcharge), inter alia, if the holder directly held at least 10% of the registered share capital (Grundkapital oder Stammkapital) of Evotec (or, arguably, ADSs representing at least 10% of the registered share capital (Grundkapital oder Stammkapital) of Evotec) at the beginning of the calendar year (“Qualifying Dividends”). Five percent of the capital gains and five percent of the Qualifying Dividends are treated as non-deductible business expenses, respectively, and, as such, are subject to corporate income tax (including solidarity surcharge); actual business expenses incurred to generate dividends may be deducted. The acquisition of a participation of at least 10% during a calendar year is deemed to have occurred at the beginning of such calendar year for the determination of whether a dividend is a Qualifying Dividend. Participations in the share capital of Evotec held through a partnership, including co-entrepreneurships (Mitunternehmerschaften), are attributable to the respective partner only on a pro rata basis at the ratio of its entitlement to the profits of the partnership. Moreover, actual business expenses allocable to the dividends are deductible.
Capital gains and dividend income of a German tax resident corporation are generally subject to German trade tax of approximately 7.0% to 21.0% depending on the multiplier applied by the relevant municipality. The 95% exemption for capital gains generally applies also for trade tax purposes.
However, the amount of any dividends after deducting business expenses related to the dividends is not subject to trade tax if the corporation directly or indirectly held at least 15% of Evotec’s registered share capital at the beginning of the relevant tax assessment period. In this case, the exemption of 95% of the dividend income also applies for trade tax purposes. Losses from the sale of ADSs are generally not tax deductible for corporate income tax and trade tax purposes.
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Regarding individuals holding ADSs as business assets, 60% of dividends and capital gains are taxed at the individual’s personal income tax rate (plus up to 5.5% solidarity surcharge (Solidaritätszuschlag) thereon). Correspondingly, only 60% of business expenses related to the dividends and capital gains as well as losses from the sale of ADSs are principally deductible for income tax purposes.
Since 2021, the basis for the calculation of the solidarity surcharge (Solidaritätszuschlag)) and, if applicable, church tax (Kirchensteuer) has been reduced for certain individuals subject to tax assessments (other than withholding taxes), and in certain cases, the solidarity surcharge has been eliminated for individuals. Church tax (Kirchensteuer) may affect the withholding tax rate as described above in “—ADSs as Private Assets (Privatvermögen).” The dividend income and 60% of the capital gains are generally subject to trade tax, which is fully or partly creditable against the individual’s personal income tax by a lump-sum method (and such credit also reduces the solidarity surcharge (Solidaritätszuschlag) and, if applicable, church tax (Kirchensteuer)). Dividends (after deduction of business expenses economically related thereto) are exempt from trade tax if the holder held at least 15% of Evotec’s registered share capital at the beginning of the relevant tax assessment period.
German Inheritance and Gift Tax (Erbschaft- und Schenkungsteuer)
The transfer of ADSs to another person by inheritance or gift should be generally subject to German inheritance and gift tax—applying the principles set forth in the ADR Tax Circular although the ADR Tax Circular does not explicitly refer to this tax—only if:
| (i) | The decedent or donor or heir, beneficiary or other transferee (a) maintained his or her domicile or a usual residence in Germany, (b) had its place of management or registered office in Germany at the time of the transfer, (c) is a German citizen who has spent no more than five consecutive years outside of Germany without maintaining a domicile in Germany or (d) is a German citizen who serves for a German entity established under public law and is remunerated for his or her service from German public funds (including family members who form part of such person’s household, if they are German citizens) and is only subject to estate or inheritance tax in his or her country of domicile or usual residence with respect to assets located in such country (special rules apply to certain former German citizens who neither maintain a domicile nor have their usual residence in Germany); or |
| (ii) | At the time of the transfer, the ADSs are held by the decedent or donor as business assets forming part of a permanent establishment in Germany or for which a permanent representative in Germany has been appointed; or |
| (iii) | The ADSs subject to such transfer form part of a portfolio that represents at the time of the transfer 10% or more of the registered share capital of Evotec and that the decedent or donor has held directly or indirectly, either alone or together with related persons. |
The Agreement between the Federal Republic of Germany and the United States of America for the avoidance of double Taxation with respect to taxes on inheritances and gifts as of December 21, 2000 (Abkommen zwischen der Bundesrepublik Deutschland und den Vereinigten Staaten von Amerika zur Vermeidung der Doppelbesteuerung auf dem Gebiet der Nachlass-, Erbschaft- und Schenkungssteuern in der Fassung vom 21. Dezember 2000), hereinafter referred to as the “United States-Germany Inheritance and Gifts Tax Treaty,” provides that the German inheritance tax or gift tax can, with certain restrictions, only be levied in the cases of
(i) and (ii) above. Special provisions apply to certain German citizens living outside of Germany and former German citizens.
Other Taxes
No German transfer tax, value-added tax, stamp duty or similar taxes are assessed on the purchase, sale, or other transfer of ADSs. If certain requirements are met, an entrepreneur may opt, however, for value-added tax on transactions that are otherwise tax-exempt. Net wealth tax (Vermögensteuer) is currently not imposed in Germany.
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Material U.S. Federal Income Tax Considerations
The following is a discussion of material U.S. federal income tax consequences to U.S. Holders, as defined below, of owning and disposing of our ADSs. It does not describe all tax considerations that may be relevant to a particular person’s decision to acquire the ADSs and the ownership and disposition thereof. This discussion applies only to a U.S. Holder that holds the ADSs as capital assets for U.S. federal income tax purposes, and this discussion applies only to such ADSs. This discussion assumes the ADS are denominated in U.S. dollars. This discussion is general in nature, and it does not describe all of the U.S. federal income tax consequences under provisions of the U.S. Internal Revenue Code of 1986 as amended (the “Code”) that may be relevant in light of the U.S. Holder’s particular circumstances, including but not limited to state and local tax consequences, alternative minimum tax consequences, the potential application of the Medicare contribution tax, estate or gift tax consequences, any tax consequences other than U.S. federal income tax consequences, and tax consequences applicable to U.S. Holders subject to special rules, such as:
| ● | Certain financial institutions including banks and insurance companies. |
| ● | Regulated investment companies, real estate investment trusts, certain former citizens, or residents of the United States, “controlled foreign corporations,” “passive foreign investment companies,” corporations that accumulate earnings to avoid U.S. federal income tax, or expatriated entities subject to Section 7874 of the Code. |
| ● | Dealers or traders in securities who use a mark-to-market method of tax accounting. |
| ● | Persons holding ADSs as part of a hedging transaction, straddle, wash sale, conversion transaction or other integrated transaction or persons entering a constructive sale with respect to the ADSs. |
| ● | Persons whose functional currency for U.S. federal income tax purposes is not the U.S. dollar. |
| ● | Entities or arrangements classified as partnerships for U.S. federal income tax purposes or other pass-through entities or investors in such entities, |
| ● | Tax-exempt entities, including an “individual retirement account” or “Roth IRA”. |
| ● | Any persons directly or indirectly acquiring our ADSs in connection with the performance of services. |
| ● | Persons who are required to accelerate the recognition of any item of gross income with respect to ADSs because of such income being recognized on an applicable financial statement. |
| ● | Persons that own or are deemed to own directly or indirectly ten percent or more of our capital stock, including shares represented by ADSs, (by vote or value); or |
| ● | Persons holding ADSs in connection with a trade or business, permanent establishment, or fixed base conducted outside of the United States. |
If an entity or arrangement that is classified as a partnership for U.S. federal income tax purposes holds ADSs, the U.S. federal income tax treatment of a partner will generally depend on the status of the partner and the activities of the partner and the partnership. Partnerships holding ADSs and partners in such partnerships should consult their tax advisors as to the U.S. federal income tax consequences of owning and disposing of the ADSs.
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This discussion is based on the Code, administrative pronouncements, judicial decisions, final, temporary and proposed (to the extent to which taxpayers may rely thereon) Treasury Regulations, and the income tax treaty between Germany and the United States (the “Treaty”), all as of the date hereof, any of which is subject to change or differing interpretations, possibly with retroactive effect, so as to result in U.S. federal income tax consequences different from those discussed below. It is also based in part on representations by the depositary and assumes that each obligation under the deposit agreement and any related agreement will be performed in accordance with its terms. We have not sought, and do not expect to seek, any ruling from the U.S. Internal Revenue Service (the “IRS”) with respect to the statements made and the conclusions reached in the following summary, and there can be no assurance that the IRS or a court would agree with our statements and conclusions or that a court would not sustain any challenge by the IRS in the event of litigation.
A “U.S. Holder” is a holder who, for U.S. federal income tax purposes, is a beneficial owner of ADSs, who is eligible for the benefits of the Treaty and who is:
| (i) | an individual who is a citizen or individual resident of the United States. |
| (ii) | a corporation, or other entity taxable as a corporation, created or organized in or under the laws of the United States, any state therein, or the District of Columbia. |
| (iii) | an estate, the income of which is subject to U.S. federal income taxation regardless of its source; or |
| (iv) | a trust if either (1) a court within the United States can exercise primary jurisdiction over the administration of the trust and one or more U.S. persons have the authority to control all substantial decisions of the trust, or (2) the trust has a valid election in effect under applicable Treasury Regulations to be treated as a U.S. person. |
In general, a U.S. Holder who owns ADSs will be treated as the owner of the underlying ordinary shares represented by those ADSs for U.S. federal income tax purposes. Accordingly, no gain or loss will be recognized if a U.S. Holder exchanges ADSs for the underlying ordinary shares represented by those ADSs. U.S. Holders are urged to consult their tax advisors concerning the U.S. federal, state, and local and non-U.S. tax consequences to them of the exchange of ADSs for the underlying ordinary shares represented by those ADSs, as well as the ownership and disposition of such ordinary shares in light of their particular circumstances.
The U.S. Treasury has expressed concern that parties to a pre-release of American depositary shares, or intermediaries in the chain of ownership between holders and the issuer of the security underlying the American depositary shares, may be taking actions that are inconsistent with the claiming of foreign tax credits by holders of American depositary shares. These actions would also be inconsistent with the claiming of the reduced rate of tax, described below, applicable to dividends received by certain non-corporate holders. Accordingly, the creditability of German taxes, and the availability of the reduced tax rate for dividends received by certain non-corporate U.S. Holders, each described below, could be affected by actions taken by such parties or intermediaries.
U.S. Holders are urged to consult their tax advisors concerning the U.S. federal, state, local, and non-U.S. tax consequences of owning and disposing of ADSs in their particular circumstances. In particular, because our group currently includes U.S. subsidiaries, (i.e., Evotec (US), Inc. and Just - Evotec Biologics Inc.) and therefore under current law our foreign subsidiaries are treated as controlled foreign corporations (regardless of whether we are or are not treated as a controlled foreign corporation), any U.S. Holder that owns or is deemed to own ten percent or more of our capital stock, directly or through ADSs, (by vote or value) is urged to consult its tax advisor regarding the potential application of the “Subpart F income” and “global intangible low-taxed income” rules to an investment in our ADSs.
THIS SUMMARY IS FOR GENERAL INFORMATION PURPOSES ONLY, AND IS NOT INTENDED TO BE, AND SHOULD NOT BE CONSTRUED TO BE, LEGAL OR TAX ADVICE TO ANY PARTICULAR HOLDER. PROSPECTIVE INVESTORS ARE URGED TO CONSULT THEIR TAX ADVISORS WITH REGARD TO THE APPLICATION OF THE U.S. FEDERAL INCOME TAX LAWS, AS WELL AS THE APPLICATION OF U.S. NON- INCOME TAX LAWS AND THE LAWS OF ANY STATE, LOCAL, OR NON-U.S. JURISDICTION, IN LIGHT OF THEIR PARTICULAR SITUATION.
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Dividends
As discussed above under “Dividend Policy,” we do not expect to make distributions on our ADSs soon. If we do make distributions of cash or other property, subject to the PFIC rules described below, distributions paid on ADSs, other than certain pro rata distributions of ordinary shares, will generally be treated as dividends to the extent paid out of our current or accumulated earnings and profits (as determined under U.S. federal income tax principles). To the extent a distribution with respect to ADSs exceeds our current or accumulated earnings and profits, as determined under U.S. federal income tax principles, the distribution will be treated, first, as a tax-free return of the U.S. Holder’s investment, up to the holder’s adjusted tax basis in its ADSs, and, thereafter, as capital gain, which is subject to the tax treatment described below in “—Gain on Sale, Exchange or Other Taxable Disposition.” Because we do not, and do not intend to, maintain calculations of our earnings and profits under U.S. federal income tax principles, we expect that distributions generally will be reported to U.S. Holders as dividends, even if that distribution would otherwise be treated as a non-taxable return of capital or as capital gain under the rules described above. If and for so long as our ADSs are listed on the Nasdaq or another established securities market in the United States (in the case of ADSs) or if and for so long as we are eligible for benefits under the Treaty, dividends paid to certain non-corporate U.S. Holders may be eligible for taxation as “qualified dividend income” if we are not treated as a PFIC with respect to the U.S. Holder in the taxable year in which the dividend is paid and were not treated as a PFIC with respect to the U.S. Holder in the preceding taxable year, and if certain minimum holding period and other requirements are met, and therefore, subject to applicable limitations and the discussion above regarding concerns expressed by the U.S. Treasury, may be taxable at rates not in excess of the long-term capital gain rate then applicable to such U.S. Holders. U.S. Holders should consult their tax advisors regarding the availability of the reduced tax rate on dividends in their circumstances. The amount of a dividend will include any amounts withheld by us in respect of German income taxes. Subject to the PFIC rules described below, the amount of the dividend will be treated as foreign-source dividend income to U.S. Holders and will not be eligible for the dividends-received deduction generally available to U.S. corporations under the Code. For U.S. foreign tax credit purposes, the dividends will generally be treated as passive category income. Subject to the PFIC rules described below, dividends will be included in a U.S. Holder’s income on the date of the depositary’s receipt of the dividend. The amount of any dividend income paid in euros will be the U.S. dollar amount calculated by reference to the exchange rate in effect on the date of actual or constructive receipt, regardless of whether the payment is in fact converted into or exchanged for U.S. dollars at that time. If the dividend is converted into U.S. dollars on the date of receipt, a U.S. Holder should not be required to recognize foreign currency gain or loss in respect of the dividend income. A U.S. Holder may have foreign currency gain or loss if the dividend is converted into U.S. dollars after the date of receipt. Generally, any gain or loss resulting from currency exchange fluctuations during the period from the date the dividend payment is included in income to the date the payment is converted into U.S. dollars will be treated as ordinary income or loss and will not be eligible for the special tax rate applicable to qualified dividend income. This gain or loss will generally be U.S.-source gain or loss for foreign tax credit purposes.
Subject to applicable limitations, some of which vary depending upon the U.S. Holder’s particular circumstances, and subject to the discussion above regarding concerns expressed by the U.S. Treasury, the German tax withheld in accordance with the Treaty at a rate not exceeding the rate provided by the Treaty and paid over to the German taxing authority will be creditable or deductible against a U.S. Holder’s U.S. federal income tax liability. To the extent a refund of the tax withheld is available to a U.S. Holder under German law or under the Treaty, the amount of tax withheld that is refundable will not be eligible for credit against a U.S. Holder’s U.S. federal income tax liability (and will not be eligible for the deduction against U.S. federal taxable income described below) and German taxes withheld in excess of the rate applicable under the Treaty will not be eligible for credit against a U.S. Holder’s U.S. federal income tax liability. In lieu of claiming a foreign tax credit, U.S. Holders may, at their election, deduct foreign taxes, including any German income tax, in computing their taxable income, subject to generally applicable limitations under U.S. law. An election to deduct foreign taxes instead of claiming foreign tax credits applies to all foreign taxes paid or accrued in the taxable year. The rules governing foreign tax credits are complex, and U.S. Holders should consult their tax advisors regarding the creditability of foreign taxes in their circumstances.
Gain On Sale, Exchange, or Other Taxable Disposition
Subject to the PFIC rules described below, gain or loss realized on the sale or other taxable disposition of ADSs will be capital gain or loss, and will be long-term capital gain or loss if the U.S. Holder held the ADSs for more than one year. Long-term capital gains of non-corporate U.S. Holders are generally taxed at preferential rates. The amount of the gain or loss will equal the difference between the U.S. Holder’s tax basis in the ADSs disposed of (which, subject to the PFIC rules described below, generally will equal the cost of such ADSs to the U.S. Holder) and the amount realized on the disposition, in each case as determined in U.S. dollars. This gain or loss will generally be U.S.-source gain or loss for foreign tax credit purposes. The deductibility of capital losses is subject to various limitations.
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If the consideration received by a U.S. Holder is not paid in U.S. dollars, the amount realized will be the U.S. dollar value of the payment received determined by reference to the spot rate of exchange on the date of the sale or other disposition. However, if the ADSs are treated as traded on an “established securities market” and a U.S. Holder is either a cash basis taxpayer or an accrual basis taxpayer that has made a special election (which must be applied consistently from year to year and cannot be changed without the consent of the IRS), such U.S. Holder will determine the U.S. dollar value of the amount realized in a non-U.S. dollar currency by translating the amount received at the spot rate of exchange on the settlement date of the sale. If a U.S. Holder is an accrual basis taxpayer that is not eligible to or does not elect to determine the amount realized using the spot rate on the settlement date, such U.S. Holder will recognize foreign currency gain or loss to the extent of any difference between the U.S. dollar amount realized on the date of sale or disposition and the U.S. dollar value of the currency received at the spot rate on the settlement date.
Passive Foreign Investment Company (“PFIC”) Considerations
Under the Code, we will be a PFIC for any taxable year in which, after the application of certain “look- through” rules with respect to subsidiaries, either (i) 75% or more of our gross income consists of “passive income,” or (ii) 50% or more of the average quarterly value of our assets consist of assets that produce, or are held for the production of, “passive income.” For purposes of the above calculations, we will be treated as if we hold our proportionate share of the assets of and directly receive our proportionate share of the income of, any other corporation in which we directly or indirectly own at least 25%, by value, of the shares of such corporation. Passive income generally includes dividends, interest, rents, certain non-active royalties, and capital gains. Although we have not performed a definitive PFIC analysis using U.S. federal income tax principles, based on certain estimates as to the composition of our income and assets, including the implied value (based on our market capitalization) of our assets that produce non-passive income during 2024, we do not believe that we were a PFIC for our 2024 taxable year. However, there can be no assurance that the IRS will agree with our conclusion. In addition, whether we or any of our subsidiaries will be a PFIC in 2024 or any future year is a factual determination that must be made annually at the close of each taxable year, and, thus, is subject to significant uncertainty, because among other things (i) we currently own a substantial amount of passive assets, including cash and securities that may give rise to passive income, (ii) the valuation of our assets that may generate non-passive income for PFIC purposes, including our intangible assets, is uncertain and may vary substantially over time, (iii) the treatment of grants as income for U.S. federal income tax purposes is unclear, and (iv) the composition of our income, if any, may vary substantially over time. The average quarterly value of our assets for purposes of determining our PFIC status for any taxable year will generally be determined in part by reference to our market capitalization, which has fluctuated and may continue to fluctuate significantly over time. Accordingly, there can be no assurance that we will not be a PFIC in 2024 or any taxable year. If we are a PFIC for any year during which a U.S. Holder holds or is deemed to hold ADSs, we generally would continue to be treated as a PFIC with respect to that U.S. Holder for all succeeding years during which the U.S. Holder holds or is deemed to hold the ADSs, even if we ceased to meet the threshold requirements for PFIC status, unless under certain circumstances the U.S. Holder makes a valid deemed sale or deemed dividend election under the applicable Treasury Regulations with respect to its ADSs.
Under attribution rules, assuming we are a PFIC, U.S. Holders will be deemed to own their proportionate shares of any Lower-tier PFICs and will be subject to U.S. federal income tax according to the rules described in the following paragraphs on (i) certain distributions by a Lower-tier PFIC and (ii) a disposition of shares of a Lower-tier PFIC, in each case as if the U.S. Holder held such shares directly, even if the U.S. Holder has not received the proceeds of those distributions or dispositions.
If we were a PFIC for any taxable year during which a U.S. Holder held or is deemed to have held ADSs (assuming such U.S. Holder has not made a timely mark-to-market election, as described below), gain recognized by a U.S. Holder on a sale or other disposition (including certain pledges) of such ADSs, or an indirect disposition of shares of a Lower-tier PFIC, would be allocated ratably over the U.S. Holder’s holding period for such ADSs. The amounts allocated to the taxable year of the sale or other disposition and to any year before we became a PFIC would be taxed as ordinary income. The amount allocated to each other taxable year would be subject to tax at the highest rate in effect for individuals or corporations, as appropriate, for that taxable year, and an interest charge would be imposed on the amount allocated to that taxable year. Further, to the extent that any distribution received by a U.S. Holder with respect to its ADSs (or a distribution by a Lower-tier PFIC to its shareholder that is deemed to be received by a U.S. Holder) exceeds 125% of the average of the annual distributions on the ADSs received during the preceding three years or the U.S. Holder’s holding period, whichever is shorter, that distribution would be subject to taxation in the same manner as gain, described immediately above.
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A U.S. Holder can avoid certain of the adverse rules described by making a mark-to-market election with respect to its ADSs, if the ADSs are “marketable.” ADSs will be marketable if they are “regularly traded” on a “qualified exchange” or other market within the meaning of applicable Treasury Regulations. If the mark-to-market election is available and a U.S. Holder makes the mark-to-market election, it generally will recognize as ordinary income any excess of the fair market value of the ADSs at the end of each taxable year over their adjusted tax basis. Accordingly, such mark-to-market election may accelerate the recognition of income without a corresponding receipt of cash. An electing U.S. Holder will recognize an ordinary loss in respect of any excess of the adjusted tax basis of the ADSs over their fair market value at the end of the taxable year (but only to the extent of the net amount of income previously included because of the mark-to-market election). If a U.S. Holder makes the election, the U.S. Holder’s tax basis in the ADSs will be adjusted to reflect the income or loss amounts recognized. Any gain recognized on the sale or other disposition of the ADSs, as applicable, in a year when we are a PFIC will be treated as ordinary income and any loss will be treated as an ordinary loss (but only to the extent of the net amount of income previously included because of the mark-to-market election). U.S. Holders should consult their tax advisors regarding the availability and advisability of making a mark-to-market election in their particular circumstances. The mark-to-market election applies to the taxable year for which the election is made and all subsequent taxable years, unless the ADSs cease to be treated as “marketable” for purposes of the PFIC rules or the IRS consents to its revocation.
In addition, to avoid the application of the foregoing rules, a United States person that owns stock in a PFIC for U.S. federal income tax purposes may make a “qualified electing fund” election (a “QEF Election”) with respect to such PFIC, and each PFIC in which the PFIC holds equity interests, if the PFIC provides the information necessary for such election to be made. To make such an election, a United States person would be required to make the QEF Election for each PFIC by attaching a separate properly completed IRS Form 8621 for each PFIC to the United States person’s timely filed U.S. federal income tax return generally for the first taxable year that the entity is treated as a PFIC with respect to the United States person. A U.S. Holder generally may make a separate election to defer payment of taxes on the undistributed income inclusion under the QEF rules, but if deferred, any such taxes are subject to an interest charge. If a United States person makes a QEF Election with respect to a PFIC, the United States person will be currently taxed on its pro rata share of the PFIC’s ordinary earnings and net capital gain (at ordinary income and capital gain rates, respectively) for each taxable year that the entity is classified as a PFIC and will not be required to include such amounts in income when actually distributed by the PFIC. There is no assurance that we will provide information necessary for U.S. Holders to make QEF Elections. If a U.S. Holder makes a QEF Election with respect to us, any distributions paid by us out of our earnings and profits that were previously included in the U.S. Holder’s income under the QEF Election will not be taxable to the U.S. Holder. A U.S. Holder will increase its tax basis in its ADSs by an amount equal to any income included under the QEF Election and will decrease its tax basis by any amount distributed, if any, on the ADSs that is not included in its income. In addition, a U.S. Holder will recognize capital gain or loss on the disposition of ADSs in an amount equal to the difference between the amount realized and its adjusted tax basis in the ADSs. U.S. Holders should note that if they make QEF Elections with respect to Lower-tier PFICs, if any, and us they might be required to pay U.S. federal income tax with respect to their ADSs, for any taxable year significantly in excess of any cash distributions, if any, received on the ADSs, as applicable, for such taxable year. U.S. Holders should consult their tax advisors regarding making QEF Elections in their particular circumstances.
In addition, if we were a PFIC or, with respect to a particular U.S. Holder, were treated as a PFIC for the taxable year in which we paid a dividend or for the prior taxable year, the preferential dividend rates discussed above with respect to dividends paid to certain non-corporate U.S. Holders would not apply.
If a U.S. Holder owns ADSs during any year in which we are a PFIC, the U.S. Holder generally must file annual reports, containing such information as the U.S. Treasury may require on IRS Form 8621 (or any successor form) with respect to us, generally with the U.S. Holder’s federal income tax return for that year, unless otherwise specified in the instructions with respect to such form. The failure to file IRS Form 8621 could result in the imposition of penalties and the extension of the statute of limitations with respect to U.S. federal income tax return.
The IRS has finalized Treasury Regulations that address various issues related to determining whether a foreign corporation is a PFIC and whether a U.S. shareholder holds PFIC stock and has released proposed Treasury Regulations that address various issues related to determining whether a foreign corporation is a PFIC. These final Treasury Regulations and proposed Treasury Regulations (if finalized) may affect whether we are a PFIC in 2024 or any future year. You should consult your tax advisor regarding the effect, if any, these Treasury Regulations may have, or such proposed Treasury Regulations would have, on the determination of our PFIC status.
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U.S. Holders should consult their tax advisors concerning our potential PFIC status and the potential application of the PFIC rules. The U.S. federal income tax rules relating to PFICs are very complex. U.S. Holders are strongly urged to consult their tax advisors with respect to the impact of PFIC status on the purchase, ownership and disposition of our ADSs, as applicable, the consequences to them of an investment in a PFIC (and any Lower-tier PFICs), any elections available with respect to our ADSs and the IRS information reporting obligations with respect to the purchase, ownership and disposition of shares of a PFIC (including any ADSs representing such shares).
Information Reporting and Backup Withholding
Payments of dividends and sales proceeds that are made within the United States or through certain U.S.-related financial intermediaries generally are subject to information reporting, and may be subject to backup withholding, unless (i) the U.S. Holder is a corporation or other exempt recipient or (ii) in the case of backup withholding, the U.S. Holder provides a correct taxpayer identification number and certifies that it is not subject to backup withholding generally on an IRS Form W-9.
Backup withholding is not an additional tax. The amount of any backup withholding from a payment to a U.S. Holder will be allowed as a credit against the U.S. Holder’s U.S. federal income tax liability and may entitle it to a refund if the required information is timely furnished to the IRS.
Information Reporting with Respect to Foreign Financial Assets
Certain U.S. Holders who are individuals and certain entities may be required to report information relating to an interest in the ADSs, subject to certain exceptions (including an exception for ADSs held in accounts maintained by certain U.S. financial institutions). Such U.S. Holders who fail to timely furnish the required information may be subject to a penalty. U.S. Holders should consult their tax advisors regarding whether they are obligated to report information relating to their ownership and disposition of ADSs.
| F. | Dividends and paying agents. |
Not applicable.
| G. | Statements by experts. |
Not applicable.
| H. | Documents on display. |
We are subject to the information reporting requirements of the Exchange Act applicable to foreign private issuers. Accordingly, we are required to file reports and other information with the SEC, including annual reports on Form 20-F and reports on Form 6-K. The SEC maintains an internet website that contains reports and other information about issuers, like us, that file electronically with the SEC. The address of that website is www.sec.gov.
| I. | Subsidiary Information. |
Not applicable.
| J. | Annual Report to Security Holders |
Not applicable.
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Item 11. Quantitative and Qualitative Disclosures about Market Risk.
We are exposed to several financial risks concerning specific areas including but not limited to foreign exchange risk, interest risk, liquidity risk and credit risk. Market risk is the risk that changes in market conditions will affect our results of operations or the value of the financial instruments held.
Our business is also subject to other risks and uncertainties that we describe from time to time in our public filings. See Item 3.D, “Key information — Risk factors.” Developments in any of these areas could cause our results to differ materially from the results that we or others have projected or may project.
Foreign Exchange Risk
We operate via our Euro zone companies, mainly in Germany, Italy, France, and Austria, but we also conduct business in the United Kingdom and the United States. Our consolidated financial statements are reported in Euros. Our exposure to the risk of changes in foreign exchange rates relates primarily to our operating activities and we carry both translational and transactional foreign exchange risk. We generate a significant portion of our revenue and incur a significant portion of our expenses in certain non-Euro currencies, mainly U.S. dollars and pound sterling. We hold our deposits primarily in three major operating currencies (Euro, U.S. dollars and pound sterling). For the year ended December 31, 2024, 62% and 10% of our revenue and 31% and 18% our cost of revenue was in U.S. dollars and pound sterling, respectively compared to 65% and 11% our revenue and 28% and 20% our cost of revenue was in U.S. dollars and pound sterling, respectively for the year ended December 31, 2023.
We currently engage in hedging activities and use forward contracts and spot transactions to convert U.S. dollars to Euros and pound sterling by means of mitigating our exposure to exchange rate fluctuations.
Translational risk:
Exchange rate fluctuations between the applicable foreign currency and the Euro will affect the translation of foreign subsidiaries’ financial results into Euro for the purpose of reporting our consolidated statements of comprehensive income. The process by which we translate each foreign subsidiary’s financial results to Euro is as follows:
| ● | assets and liabilities including goodwill of foreign subsidiaries with functional currencies other than the Euro are translated into Euro using the respective exchange rates at the end of the reporting period. |
| ● | income statements of subsidiaries are translated using monthly average exchange rates during the respective period. |
Gains or losses resulting from translating foreign functional currency financial statements are recognized in other comprehensive income and realized through P&L on termination of the respective position.
Transactional risk:
We record all foreign currency transaction and remeasurement gains and losses as other finance income (expense), net on the consolidated income statement. We do not have significant operations in countries considered highly inflationary.
Interest Rate Risk
We are exposed to interest rate risk through variable interest-bearing loans as well as current investments, in Germany, but also at our foreign entities. The fair value of debt varies from the carrying amount if there is a difference between the underlying interest rate to the market interest rate.
The Group is exposed to interest rate risk through variable interest - bearing loans. These interest rate risks are considered immaterial.
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Liquidity Risk
Liquidity risk is the risk that we will not be able to meet our financial obligations as they fall due. Our approach to managing liquidity is to ensure, as far as possible, that we will always have sufficient liquidity to meet liabilities when due, under both normal and stressed conditions, without incurring unacceptable losses or risking damage to our reputation.
Credit Risk
Credit risk is the risk of financial loss if a customer or counterparty to a financial instrument fails to meet their contractual obligations. Our credit risk arises primarily from cash and cash equivalents and other financial assets, including deposits with banks and financial institutions, as well as credit exposures to customers, including outstanding receivables and contract assets. We attempt to limit our exposure to credit risk by maintaining our bank accounts and short-term deposits with well-established financial institutions. For our credit exposure to customers, we perform ongoing credit evaluations of our customers’ financial condition and maintain an appropriate specific allowance for uncollectible accounts receivable based upon the expected collectability of all accounts receivable. Our accounts receivables are generally unsecured and are not backed by collateral from our customers. As of December 31, 2024, and December 31, 2023, one customer accounted for 9% and 6% of our trade receivables, respectively. Concentrations of credit risk with respect to trade accounts receivables are generally limited by geographically diverse customers as well as industry -group wise differentiated customers (pharma, biotech, foundations),and our monitoring procedures.
Item 12. Description of Securities Other than Equity Securities.
| A. | Debt Securities. |
Not applicable.
| B. | Warrants and Rights. |
Not applicable.
| C. | Other Securities. |
Not applicable.
| D. | American Depositary Shares. |
JPMorgan Chase Bank, N.A., as depositary, registers and delivers the American Depositary Shares, or the ADSs. Each ADS represents one-half of one share (or a right to receive one share) deposited with BNP Paribas (Deutschland) OHG as custodian for the depositary in Germany. Each ADS also represents any other securities, cash, or other property, which may be held by the depositary. The deposited shares together with any other securities, cash or other property held by the depositary are referred to as the deposited securities. The depositary’s office at which the ADSs will be administered, and its principal executive office are located at 383 Madison Avenue, Floor 11, New York, New York 10179.
For more complete information, you should read the entire amended and restated deposit agreement and the form of American Depositary Receipt. A copy of the amended and restated deposit agreement and the form of American Depositary Receipt are incorporated by reference as Exhibits 2.1 and 2.2 of this annual report, respectively.
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Fees and Expenses
Persons depositing or withdrawing shares or ADS holders must pay:
$5.00 (or less) per 100 ADSs (or portion of 100 ADSs) |
| Issuance of ADSs, including issuances resulting from a distribution of shares or rights or other property Cancellation of ADSs for the purpose of withdrawal, including if the deposit agreement terminates |
$0.05 (or less) per ADS | Any cash distribution to ADS holders | |
A fee equivalent to the fee that would be payable if securities distributed to you had been shares and the shares had been deposited for issuance of ADSs | Distribution of securities distributed to holders of deposited securities (including rights) that are distributed by the depositary to ADS holders | |
an aggregate fee of U.S.$0.05 or less per ADS per calendar year (or portion thereof) | For services performed by the Depositary in administering the ADSs | |
Registration or transfer fees | Depositary services Transfer and registration of shares on our share register to or from the name of the depositary or its agent when you deposit or withdraw shares | |
Charges of the depositary | SWIFT, cable and facsimile transmission and delivery charges. including a cancellation transaction fee of $15.00 will be charged per cancellation request (when expressly provided in the deposit agreement or disclosed on adr.com) | |
Fees of the depositary | Converting foreign currency to U.S. dollars, as disclosed on adr.com | |
Taxes and other governmental charges the depositary or the custodian has to pay on any ADSs or shares underlying ADSs, such as stock transfer taxes, stamp duty or withholding taxes | As necessary | |
Any charges incurred by the depositary or its agent for servicing the deposited securities | As necessary |
The depositary collects its fees for delivery and surrender of ADSs directly from investors depositing shares or surrendering ADSs for the purpose of withdrawal or from intermediaries acting for them. The depositary collects fees for making distributions to investors by deducting those fees from the amounts distributed or by selling a portion of distributable property to pay the fees. The depositary may collect its annual fee for depositary services by deduction from cash distributions, by directly billing investors, or by charging the book-entry system accounts of participants acting for them. The depositary may collect any or all of its fees by deduction from any cash distribution payable (or by selling a portion of securities or other property distributable) to ADS holders that are obligated to pay those fees. The depositary may generally refuse to provide fee-attracting services until its fees for those services are paid.
From time to time, the depositary may make payments to us to reimburse us for costs and expenses generally arising out of establishment and maintenance of the ADS program, waive fees and expenses for services provided to us by the depositary or share revenue from the fees collected from ADS holders. In performing its duties under the deposit agreement, the depositary may use brokers, dealers, foreign currency dealers or other service providers that are owned by or affiliated with the depositary and that may earn or share fees, spreads, or commissions.
The depositary may convert currency itself or through any of its affiliates and, in those cases, acts as principal for its own account and not as agent, advisor, broker or fiduciary on behalf of any other person and earns revenue, including, without limitation, transaction spreads, that it will retain for its own account. The revenue is based on, among other things, the difference between the exchange rate assigned to the currency conversion made under the deposit agreement and the rate that the depositary or its affiliate receives when buying or selling foreign currency for its own account. The depositary makes no representation that the exchange rate used or obtained in any currency conversion under the deposit agreement will be the most favorable rate that could be obtained at the time or that the method by which that rate will be determined will be the most favorable to ADS holders, subject to the depositary’s obligations under the deposit agreement. The methodology used to determine exchange rates used in currency conversions is available at adr.com.
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PART II
Item 13. Defaults, Dividend Arrearages and Delinquencies.
None.
Item 14. Material Modifications to the Rights of Security Holders and Use of Proceeds.
| A. | Material modifications to instruments. |
Not applicable.
| B. | Material modification to rights. |
Not applicable.
| C. | Withdrawal or submission of assets. |
Not applicable.
| D. | Changes in trustees or paying agents. |
Not applicable.
| E. | Use of proceeds. |
On November 3, 2021, our registration statement on Form F-1 (File No. 333-260143), as amended, was declared effective by the SEC for our initial public offering of our ADSs, each representing one-half of one ordinary share, no par value per share, pursuant to which we offered and sold a total of 22,995,000 of our ADSs, at a public offering price of $21.75 per share. Morgan Stanley and Bank of America (“BofA”) Securities acted as lead joint book-running managers for the offering. The offering began on November 3, 2021, and was completed on November 8, 2021.
There has been no significant change in the planned use of proceeds from our initial public offering as described in our prospectus dated November 3, 2021, and filed with the SEC on November 3, 2021. The proceeds were used as follows:
| ● | approximately $100.0 million to expand our biologics manufacturing capacity in the United States at the existing J.POD facility in Redmond, Washington by fully building out the facility to three production trains and six production bioreactors and to continue to advance our end-to-end continuous biologics manufacturing technologies. |
| ● | approximately $175.0 million for building additional J.POD capacity in Toulouse, France. |
| ● | approximately $35.0 million for expanding our precision medicine platform, which includes the expansion of our iPSC technology platform through building new capacities in Hamburg, Germany, expanding our PanOmics/ PanHunter platforms to broaden access to patient derived samples and disease relevant data as well as expanding our capabilities to analyze the growing amount of data that is core to our business model. |
| ● | approximately $115.0 million for unpartnered R&D to accelerate pipeline activities. We expect that the funds would support investments for the development of additional new programs, which could be further explored with partners in future; and |
| ● | approximately $80.0 million to expand our portfolio of investments through investments in new companies and participation in future financing rounds of our existing portfolio companies. |
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Item 15. Controls and Procedures.
| A. | Disclosure Controls and Procedures. |
As required by Rule 13a-15 under the Exchange Act, our management, including our CEO and our CFO, has evaluated the effectiveness of our disclosure controls and procedures as of the end of the period covered by this report. Disclosure controls and procedures refer to controls and other procedures designed to ensure that information required to be disclosed in the reports we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the rules and forms of the SEC. Disclosure controls and procedures include, without limitations, controls and procedures designed to ensure that information required to be disclosed by us in our reports that we file or submit under the Exchange Act is accumulated and communicated to management, including our CEO and our CFO, or persons performing similar functions, as appropriate to allow timely decisions regarding our required disclosures.
In designing and evaluating the disclosure controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives, and management is required to apply its judgement in evaluating the cost-benefit relationship of possible controls and procedures. Our management, with the participation of our CEO and CFO, carried out an evaluation of the effectiveness of our disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act) as of December 31, 2024, the end of the period covered by this annual report. Based upon that evaluation, and because of the material weaknesses described below and our inability to provide required financial information in a timely manner, management concluded that, as of December 31, 2024, our disclosure controls and procedures were not effective at the reasonable assurance level.
Notwithstanding the material weaknesses described in Management’s Report on Internal Control over Financial Reporting, our management has concluded that our financial statements for the periods covered by and included in this annual report are prepared in accordance with IFRS as issued by the International Accounting Standard Board (“IASB”) and fairly present, in all material respects, our financial position, results of operations and cash flows for each of the periods presented herein.
B.Management’s annual report on internal control over financial reporting.
Our management is responsible for establishing and maintaining adequate internal control over financial reporting, as defined in Rules 13-15(f) and 15d-15(f) under the Exchange Act of 1934, as amended, for the Company. Internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of the financial statement in accordance with IFRS that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of a company’s assets, (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that a company’s receipts and expenditures are being made only in accordance with authorizations of a company’s management and directors, and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition of a company’s assets that could have a material effect on the financial statements.
Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.
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Under the supervision and with the participation of our CEO and CFO, management assessed the effectiveness of our internal control over financial reporting as of December 31, 2024, based on the framework set forth in Internal Control – Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission. Based on this assessment, our management concluded that our internal control over financial reporting was not effective as of December 31, 2024, because of the material weaknesses described below.
A material weakness is a deficiency, or a combination of deficiencies, in internal control over financial reporting such that there is a reasonable possibility that a material misstatement of annual or interim financial statements will not be prevented or detected on a timely basis.
Material Weaknesses Identified
As of December 31, 2024, we did not maintain appropriately designed controls impacting the control environment, risk assessment procedures, and effective monitoring controls to prevent or detect material misstatements to the consolidated financial statements. We identified a material weakness in our internal control over financial reporting related to revenue recognition. Furthermore, we did not design and maintain effective controls related to the review and approval of manual journal entries. Specifically certain journal entries were prepared and posted without sufficient documentation and adequate review. In addition, we did not fully maintain effective controls over the accounting assessment of complex and non-standard accounting matters and associated presentation and disclosures.
Remediation Activities and Plans
Management is committed to remediating the material weaknesses in a timely fashion. As of the reporting date, we have already executed several measures and are actively progressing with additional enhancements over the control, process and tool implementations as outlined in our comprehensive remediation plan. These actions will address the material weaknesses in internal control over financial reporting. The remediation plan considers the following measures:
| ● | We have launched a project aimed at thoroughly harmonizing and automating the end-to-end order-to-cash process, encompassing the identification and remediation of challenges associated with revenue recognition; |
| ● | In the 2024 financial year, we automated the approval process for manual postings in our ERP system through a workflow that adheres to the four-eyes principle and segregation of duties. This workflow requires attaching appropriate documentation in compliance with SOX requirements, serving as evidence for the approver. Documentation standards have been established in a policy, communicated, and reinforced through training for control personnel. A material weakness arose because some manual postings lacked SOX-compliant documentation and sufficient review on completeness and accuracy of underlying evidence. To address this, we will enhance training, expand the existing policy, and further automate processes to minimize manual postings and reduce inherent risks. |
| ● | For analyzing and assessing the recoverability of deferred taxes, our control mechanisms require the involvement of external experts, whose findings are reviewed and evaluated internally. The final assessment resulted in a material adjustment, which management corrected before publishing the company’s 2024 consolidated financial statements. To enhance this process, we have developed improvement measures that establish clear criteria for impairment assessment, formalized in internal tax accounting policies and subject to audit. |
We believe we are making progress toward achieving the effectiveness of our internal control over financial reporting and disclosure controls and procedures. The actions we are taking are subject to ongoing senior management review, as well as Audit and Compliance Committee oversight. We are committed to establishing and maintaining a strong internal control environment and implementing measures designed to help ensure that control deficiencies contributing to the material weaknesses are remediated as soon as possible.
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As we work to remediate our material weaknesses and continue to evaluate and work to improve our internal control over financial reporting, our management is likely to determine that additional steps or measures may be necessary to address and remediate the material weaknesses. Management may also determine that it is necessary to modify the above-mentioned remediation efforts depending on the circumstances and Company needs. We cannot assure you that these remediation efforts will be successful or that its internal control over financial reporting will be effective in accomplishing all control objectives all of the time. Management will continue to assess the effectiveness of these remediation efforts in connection with its evaluations of internal control over financial reporting.
In addition to the remediation steps discussed above, we continue with changes included implementation of new controls, identification of key controls, evaluation and, where necessary, improvement of the existing controls. This included an evaluation of business process controls, information technology general controls, key reports as well as entity level controls in all material subsidiaries of Evotec SE.
Remediation of Previously Identified Material Weaknesses
In connection with the preparation and audit of our consolidated financial statements for the financial year ended December 31, 2023, we previously identified a material weakness related to inadequate data and access management controls (including Segregation of duties), foreign exchange rates in the accounting system, completeness and existence of fixed assets, segment reporting and valuation of equity instruments and associated convertible loans and controls over IT system access management. The implementation of an adapted process in our ERP system enabled us to create a control design that could eliminate the material weaknesses for segregation of duties and foreign exchanges rates in the 2024 financial year.:
| ● | With go live date mid-April 2024, we implemented a global rights and roles concept to streamline ERP access management across our organization. These included adjusted approval rules, standardized roles and permissions aligned with job functions, reducing the likelihood of conflicting access rights. |
| ● | With go live date mid-April 2024, we implemented a daily FX upload check to verify the accuracy and completeness of FX data recorded in our systems. This included automated alerts for discrepancies or irregularities. We conducted a comprehensive review of default exchange rates used in our systems for FX transactions and implemented adjustments to default exchange rates if necessary. Our ERP system ensures restriction over the changes to authorized personnel with appropriate approvals. |
Beginning of 2024 automated processes for handling new users and deactivations in our OT system that were in place before the cyberattack have been reinstated. In addition we improved the control design and control frequency to ensure completeness and existence of fixed assets, a proper disclosure of our segment reporting and an adequate valuation of equity instruments and associated convertible loans. We concluded these material weaknesses were remediated as of December 31, 2024.
While we are implementing the measures required to fully remediate the material weaknesses, we cannot predict the success of such measures or the outcome of our assessment of these measures at this time, and we cannot assure you that we will be able to fully remediate our material weakness in the future. See “Item 3. Key Information — D. Risk factors — Risks Related to Our Business“.
C.Attestation report of the registered public accounting firm.
The effectiveness of our internal control over financial reporting as of December 31, 2024, has been audited by BDO AG Wirtschaftsprüfungsgesellschaft, an independent registered public accounting firm. Their report is included on page F-2. BDO AG Wirtschaftsprüfungsgesellschaft is a member of the Chamber of Public Accountants (Wirtschaftsprüferkammer), Berlin, Germany.
| D. | Changes in internal control over financial reporting |
Other than as described above in Item 15.B of this annual report, there were no changes to our internal control over financial reporting (as defined in Rule 13a-15(f) and 15d-15(f) under the Securities and Exchange Act of 1934) that occurred during the period covered by this Form 20-F that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
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Item 16. [Reserved]
Item 16A. Audit committee financial expert.
Our Board of directors has determined that Roland Sackers is an audit committee financial expert as defined by SEC rules and has the requisite financial sophistication under the applicable rules and regulations of the Nasdaq Stock Market. Roland Sackers is not only independent and has the required specialist knowledge and experience in the application of accounting principles and internal control processes and the audit, including sustainability reporting and its audit and assurance. Roland Sackers’ expertise in the field of accounting includes special knowledge and experience in the application of accounting principles and internal control and risk management systems, and his expertise in the field of auditing includes special knowledge and experience in the auditing of financial statements. In addition, Camilla Macapili Languille has expertise in the field of accounting, internal control, and risk management systems. The Company has determined that Roland Sackers, Camilla Macapili Languille and Dr. Constanze Ulmer-Eilfort are independent as such term is defined in Rule 10A-3 under the Exchange Act and under the listing standards of the Nasdaq Stock Market. For more information see “Item 6. Directors, Senior Management and Employees — C. Board Practices — Committees — Audit Committee.”
Item 16B. Code of Ethics.
We have adopted a Code of Ethics and Business Conduct, which covers a broad range of matters including the handling of conflicts of interest, compliance issues and other corporate policies such as insider trading and equal opportunity and non-discrimination standards. The Code of Ethics and Business Conduct applies to all our Supervisory Board members, Management Board members, directors of our subsidiaries and our affiliates and employees. The full text of the Code of Ethics and Business Conduct is available on our website at www.evotec.com. The information and other content appearing on our website does not constitute a part of this annual report and is not incorporated by reference herein. Any amendments or waivers from the provisions of the Code of Ethics and Business Conduct for members of our Supervisory or Management Boards will be disclosed on our website promptly following the date of such amendment or waiver.
Our Code of Ethics and Business Conduct also includes our policy on conflicts of interest and sets forth guidelines for employee conduct which are intended to prevent actual or perceived conflicts of interest. Under our conflicts of interest policy, employees are directed to avoid situations in which they are directly or indirectly involved in, linked to, or draw personal gain from external business activities if those activities are in any way linked to the activities of Evotec. Additionally, employees may not make use of, disclose, or share any company information that is not in the public domain or do any transactions with stock of the Company based on insider knowledge. These prohibitions also apply to the family members and close friends of employees.
Our compliance policies and procedures are designed to ensure compliance with applicable legal requirements, while at the same time implementing high ethical standards that are mandatory for both management and each employee. For example, the company requires that all board members and other employees attend electronic or face-to-face trainings tailored to specific compliance issues and risks at the company. Our compliance program is overseen by the company’s compliance officer who functions as an independent and objective body that reviews and evaluates compliance issues and concerns within our organization. The overall responsibility for the compliance management system lies with the Management Board. The Audit and Compliance Committee receives regular reports on the operation of the compliance management system.
Item 16C. Principal Accountant Fees and Services.
For information regarding the Principal Accountant Fees and Services, see note (20) Auditor’s remuneration in the notes to consolidated financial statements for the financial year 2024.
Item 16D. Exemptions from the Listing Standards for Audit Committees.
None.
Item 16E. Purchases of Equity Securities by the Issuer and Affiliated Purchasers.
None.
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Item 16F. Change in Registrant’s Certifying Accountant.
Not applicable.
Item 16G. Corporate Governance.
Evotec SE is incorporated under the laws of Germany, with securities publicly traded in the Frankfurt Stock Exchange and the United States Nasdaq. As a foreign private issuer, Nasdaq Stock Market Rule 5615(a) generally permits us to follow home country corporate governance practices instead of certain provisions of the Nasdaq Stock Market Rules. The following summarizes the principal ways in which our corporate governance practices differ from the Nasdaq corporate governance rules applicable to U.S. domestic issuers (the Nasdaq Stock Market Rules).
German Law overview
The primary sources of law relating to the corporate governance of a German company are the German Act on the Implementation of Council Regulation No. 2157/2001 of October 8, 2001, on the Statute for a European Company (Gesetz zur Ausführung der Verordnung (EG) Nr. 2157/2001 des Rates vom 8. Oktober 2001 über das Statut der Europäischen Gesellschaft (SE) – SE-Ausführungsgesetz; “SE-AG”) of December 22, 2004, and the AktG, the German Securities Trading Act (Wertpapierhandelsgesetz), the German Securities Purchase and Take Over Act (Wertpapiererwerbs- und Übernahmegesetz), the Stock Exchange Admission Regulation, and the German Commercial Code (Handelsgesetzbuch). In addition to these mandatory rules, the GCGC contains recommendations for generally accepted best practice standards for corporate governance. Pursuant to the German Stock Corporation Act, the management, and the supervisory boards of publicly listed companies like Evotec SE must publish and at all times make available to shareholders, an annual declaration that either states that company has complied with all of the recommendations of the Code or that lists the recommendations that the company has not complied with and the reasons for the deviation. Evotec has published its deviations from the Code in an official declaration on its website.
The significant differences between the corporate governance practices that we follow and those set forth in the Nasdaq Stock Market Rules applicable to domestic issuers are:
Board Structure
Nasdaq Listing Rule 5605 implies a unitary board of directors and requires mandatory independence for a majority of the members affirmatively determined via specific tests of independence. Our corporate governance structure consists of a two-tiered system consisting of a Management Board and a Supervisory Board with a clear separation of management and control and with no individuals being a member of both boards. The Management Board is responsible for managing and representing the company in its dealings with third parties, while the Supervisory Board appoints or dismisses and oversees the members of the Management Board. German law prohibits the Supervisory Board from making operational management decisions. Currently, all six of our Supervisory Board members are considered independent within the meaning of the Code. As permitted by the listing requirements of Nasdaq, we have opted out of complying with Nasdaq Listing Rule 5605(b)(2), which requires independent directors to hold regularly scheduled meetings at which only independent directors are present as this is not a requirement of our home country rules.
Audit Committee
Nasdaq Listing Rule 5605(c) requires companies to have an audit committee with a written charter covering certain specific requirements of the committee, consisting of at least three members, all members are to be independent unless specific circumstances are satisfied, members must have general financial literacy, and one member must have the special knowledge and experience of the application of accounting principles and internal control procedures demonstrable of a high level of financial sophistication. By contrast, German law does not require a separate charter for an audit committee, nor does it require that all members of the audit committee be independent or financially literate. Furthermore, German law requires only that one audit committee member has specialist knowledge in the areas of accounting and internal control processes and another member has specialist expertise in the field of auditing. Though not required by home country rules, we have adopted Nasdaq standards and currently maintain an audit committee of a majority independent members, as directed by a written charter, whom we believe all of which are financially literate and one of which is a financial expert pursuant to Item 407(d)(5) of Regulation S-K.
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Compensation Committee
In lieu of a Compensation Committee required pursuant to Nasdaq Listing Rule 5605(d), we follow home country practices and rely on the Supervisory Board to collectively determine the compensation of the CEO and all other members of the Management Board based on recommendation from the Remuneration and Compensation Committee. Pursuant to German law and in accordance with the requirements of our Articles of Association, the Supervisory Board’s compensation and nominations are determined by a Remuneration and Nomination Committee.
Meeting of Shareholders (Proxy Solicitation and Quorum).
Proxy Solicitation
Nasdaq Listing Rule 5620(b) requires companies to solicit proxies and provide proxy statements for all meetings of shareholders and to furnish such proxy solicitation(s) to Nasdaq. We do not follow Nasdaq requirements regarding the provision of proxy statements for general meetings of shareholders and rely on home country practice. Under German law, shareholders have the right to exercise their voting rights in the shareholders’ meeting through proxies appointed by them in writing. The proxies appointed by the company are obligated to vote only in accordance with the instructions of the represented shareholder.
Shareholder Quorum
Nasdaq Listing Rule 5620(c) requires an issuer to provide in its bylaws for a generally applicable quorum, and that such quorum may not be less than one-third of the outstanding voting shares. We do not follow the Nasdaq quorum requirements applicable to meetings of shareholders and rely on home country practice. German law does not require a specific quorum for the general meeting and such requirement is not stipulated in our articles of association.
Shareholder Approval of Securities Issuances
Nasdaq Listing Rule 5635 requires companies to obtain shareholder approval before undertaking certain transactions (such as, acquisitions which results in the issuance of 20% or more of outstanding share capital or voting power, change of control transactions, establishing or materially amending an equity compensation arrangement, and entering into a transaction other than a public offering involving the sale, issuance or potential issuance of shares (or securities convertible into or exercisable for shares) equal to 20% or more of outstanding share capital or 20% or more of the voting power outstanding before the issuance for less than the greater of book or market value of the stock). Consistent with the AktG, approval by the shareholders’ meeting is generally required for the issuance of any shares as well as any securities granting the respective holder the right to acquire shares (including options and convertibles).
Code of Conduct
Nasdaq Listing Rule 5610 requires companies to adopt one or more codes of conduct applicable to all directors, officers, and employees. Although there is no requirement under German law for a company to have a code of conduct, we nevertheless have one in place applying to board members and employees alike.
Item 16H. Mine Safety Disclosure.
Not applicable.
Item 16I. Disclosure Regarding Foreign Jurisdictions that Prevent Inspections.
Not applicable.
Item 16J. Insider trading policies.
Our insider trading policy, as contemplated by Item 16J. of Form 20-F, is
115
Item 16K. Cybersecurity.
Risk management and strategy
The cyber risk management process is an essential process within the information security management system (“ISMS”) of Evotec. The ISMS is a framework of policies and controls that manage information security and risk systematically and across the Company and is aligned with the baselines of ISO 27001, an international framework for information security. Information security risk management is
As previously disclosed, on April 6, 2023, Evotec was the victim of a ransomware incident that impacted our operations. The incident resulted in loss of sales and increased operating expenses related to response and recovery. The incident
In addition to implementing a new and secure IT environment, Evotec has processes in place to identify, analyze, and evaluate risks from cybersecurity threats.
Risk assessments are performed at least annually, focusing on the probability and potential impact of cybersecurity risks. Interim risk assessments are performed on a continual basis as needed, including but not limited to:
· | when new / emerging threats are identified. |
· | when changes to existing IT systems are introduced. |
· | within the specification of requirements for the acquisition, development, integration and deployment of new IT applications or appointment of new IT service suppliers (e.g., software as a service). |
· | the occurrence of a cybersecurity incident; and |
· | after the analysis of vulnerability assessment results, penetration test results and audits. |
The Company has established a cybersecurity incident response process for responding to cybersecurity incidents with defined roles and responsibilities that facilitate coordination between the Chief Information Security Officer (“CISO”) and the IT, compliance, and business departments. The incident response process describes how to prepare for, detect, respond to, and recover from cybersecurity incidents, including processes to identify, assess the severity of, mitigate, and remediate the incident, as well as to comply with applicable legal and reporting obligations.
External consultants are often
We outsource elements of our information technology including infrastructure, platform, and software services, and as a result, several third-party vendors may or could have access to confidential information. Risks arising from cooperation with service providers are considered an integral part of the supplier
116
Governance
Both the current CISO, employed since May 2024, and the interim CISO each have more than 10 years of professional experience in cyber and information security, including information risk management.
117
118
4.10† | ||
4.11† | ||
4.12† | ||
4.13† | ||
4.14† | ||
4.15 | ||
4.16 | ||
4.17† | Senior Revolving Facility Agreement, dated July 30, 2024(1). | |
8.1* | ||
10.1 | ||
11.1* | ||
12.1* | ||
12.2* | ||
13.1* | ||
13.2* | ||
15.1* | Consent of Independent Registered Public Accounting Firm BDO. | |
101* | Inline XBRL Instance Document-the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document. | |
101* | Inline XBRL Calculation Linkbase Document. | |
101* | Inline XBRL Definition Linkbase Document. | |
101* | Inline XBRL Labels Linkbase Document. | |
101* | Inline XBRL Presentation Linkbase Document. | |
104* | The cover page for the Company’s Annual Report on Form 20-F for the year ended December 31, 2024, has been formatted in Inline XBRL |
*Filed herewith.
† | Certain information has been excluded from the exhibit because it both (i) is not material and (ii) would likely cause competitive harm to the Company if publicly disclosed. |
(1) | Incorporated by reference to the Partnership’s Annual Report on Form 20-F, which was filed with the Securities and Exchange Commission on August 14, 2024. |
119
SIGNATURES
The registrant hereby certifies that it meets all of the requirements for filing on Form 20-F and that it has duly caused and authorized the undersigned to sign this annual report on its behalf.
Evotec SE | |||
By: | /s/ Christian Wojczewski | ||
Christian Wojczewski, CEO | |||
/s/ Paul Hitchin | |||
Paul Hitchin, CFO | |||
Date: | April 17, 2025 | ||
120
INDEX TO CONSOLIDATED FINANCIAL STATEMENTS
Audited Consolidated Financial Statements |
| Page |
Report of Independent Registered Public Accounting Firm ( | F-2 | |
Consolidated Income Statements for the Fiscal Years Ended December 31, 2024, 2023 and 2022 | F-7 | |
F-8 | ||
Consolidated Statements of Financial Position as of December 31, 2024 and 2023 | F-9 | |
F-12 | ||
Consolidated Statements of Cash Flows for the Fiscal Years Ended December 31, 2024, 2023 and 2022 | F-11 | |
F-13 |
F-1
Report of Independent Registered Public Accounting Firm
Shareholders and Supervisory Board
Evotec SE, Hamburg, Germany
Opinion on the Consolidated Financial Statements
We have audited the accompanying consolidated statements of financial position of Evotec SE (the “Company”) as of December 31, 2024 and 2023, the related consolidated income statements and statements of comprehensive income, changes in stockholders’ equity, and cash flows for each of the three years in the period ended December 31, 2024, and the related notes (collectively referred to as the consolidated financial statements”). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company at December 31, 2024 and 2023, and the results of its operations and its cash flows for each of the three years in the period ended December 31, 2024, in conformity with International Financial Reporting Standards as issued by the International Accounting Standards Board (IFRS).
We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the Company’s internal control over financial reporting as of December 31, 2024, based on criteria established in Internal Control – Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO) and our report dated April 14, 2025 expressed an adverse opinion thereon.
Basis for Opinion
These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on the Company’s consolidated financial statements based on our audits. We are a public accounting firm registered with the PCAOB and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.
We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement, whether due to error or fraud.
Our audits included performing procedures to assess the risks of material misstatement of the consolidated financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the consolidated financial statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements. We believe that our audits provide a reasonable basis for our opinion.
Critical Audit Matters
The critical audit matters communicated below are matters arising from the current period audit of the consolidated financial statements that were communicated or required to be communicated to the audit committee and that: (1) relate to accounts or disclosures that are material to the consolidated financial statements and (2) involved our especially challenging, subjective, or complex judgments. The communication of the critical audit matters does not alter in any way our opinion on the consolidated financial statements, taken as a whole, and we are not, by communicating the critical audit matters below, providing separate opinions on the critical audit matters or on the accounts or disclosures to which they relate.
F-2
Recoverability of goodwill
As described in Note (9) to the consolidated financial statements, goodwill amounted to € 282.9 million (14.8 % of the consolidated total assets or 29.7 % of the consolidated equity) as of December 31, 2024. Cash-generating units with allocated goodwill are subject to impairment testing by the Company at least once a year and additionally if there are indications of impairment. The valuation is carried out using a discounted cash flow method. If the carrying amount of a cash-generating unit is higher than its recoverable amount, an impairment loss is recognized in the amount of the difference. For the year ended December 31, 2024, no impairment of goodwill was recognized.
We identified the determination of the recoverability of goodwill as a critical audit matter. The impairment test for goodwill is complex and requires judgment as inherent uncertainty is involved in management’s valuation model. The primary estimates involving those judgments are future cash flows with main growth assumptions for revenues and gross margin and the discount rates used, including growth rates for the terminal value. Auditing these estimates and related assumptions involved especially challenging and subjective auditor judgment due to the nature and extent of audit evidence and effort required to address these matters, including the extent of specialized skill or knowledge needed.
The primary procedures we performed to address this critical audit matter included:
| ● | Evaluating the reasonableness of certain of management’s growth assumptions with respect to revenue and gross margin as well as discount rates used in the discounted cash flow model through: (i) comparing revenue and gross margin projections to prior period forecasts and historical periods as well as to current industry-specific market expectations, (ii) performing a sensitivity analysis on changes in discount rates and terminal value growth assumptions used in management’s valuation model, and (iii) evaluating whether the forecasts were consistent with evidence obtained in other areas of the audit. |
| ● | Utilizing personnel with specialized knowledge and skill of valuation techniques to assist in determining the appropriateness of the discounted cash flow model used and evaluating the reasonableness of the discount rates used. |
Revenue recognition from Complex contracts with customers
The Company’s revenues amounted to € 797.0 million in 2024. As described in Notes (2) and (4) to the consolidated financial statements, a significant portion of the Evotec Group’s revenues is attributable to complex contracts with customers that contain multiple performance obligations, some of which require revenue recognition over time. Some contracts contain variable transaction prices, which are dependent on the achievement of a specific success in clinical development. In case of performance obligations recognized over time, revenue is mainly measured on the basis of progress towards complete fulfillment. The progress of completion is generally measured on an input basis. To determine the input-based progress, the Company primarily uses the ratio between the number of full-time equivalents (FTEs) deployed and the total planned FTEs per performance obligation.
We identified the revenue recognition from complex contracts with customers as a critical audit matter, because significant management judgement is involved. The audit procedures addressing the identification of separate performance obligations, the determination and allocation of the transaction price, and the assessment of whether the performance obligation is recognized over time or at a point in time as well as the estimation of progress require especially challenging and subjective auditor judgment.
The primary procedures we performed to address this critical audit matter included:
| ● | Evaluating the reasonableness of revenue recognized for a risk-oriented selection and a sample of recognized revenue, through: (i) assessing the identification of separate performance obligations, (ii) evaluating the determination and allocation of the transaction price, (iii) obtaining appropriate evidence for variable components of the transaction price that achievement of the milestones is highly probable, and (iv) evaluating the appropriateness of the over-time revenue recognition vs. point in time for complex contracts with customers. |
| ● | Assessing the reasonableness of over-time revenue recognized by the Company through: (i) assessing the progress of the respective contracts by evaluating the planned and actual inputs for a sample of revenue contracts and comparing the underlying inputs to the actual performance during the year, and (ii) assessing management’s budgeting process by performing a multi-year assessment of the budgets versus actual performance of selected projects during the period. |
F-3
Valuation of unlisted equity Investments
As described in Note (15) to the consolidated financial statements, unlisted equity investments amounted to € 32.0 million at December 31, 2024. The investments in early-stage companies are mainly of a strategic nature and are made for the purpose of promoting new business models and, in particular, the development of products and/or technology platforms in pharmaceutical research. These investments are accounted for as financial assets at fair value through profit or loss unless the Company makes use of the option to measure them at fair value through other comprehensive income upon acquisition. Since there are no observable stock market prices available, the fair value is derived from external financing rounds or capital transactions with new investors, or in the absence of these, the Company uses qualitative factors such as scientific progress and assesses the liquidity situation to assist in determining the valuation. If the development is promising, the acquisition costs are assumed to be the best possible estimate of the fair value. If the investment has a possible going concern risk and there are no other promising factors, the Company assumes the carrying amount of the entity’s net asset value as the best estimate of the fair value.
We identified the determination of the fair value of unlisted equity investments as a critical audit matter due to significant management judgment as it is not based on observable market data. Auditing these estimates and related assumptions involved especially challenging and subjective auditor judgment due to the nature and extent of audit evidence which is mostly based on unobservable inputs and qualitative factors.
The primary procedures we performed to address this critical audit matter included:
| ● | Evaluating the reasonableness of the valuation of unlisted equity investments through: (i) assessing whether the valuation method applied by the executive directors is consistent with the requirements of IFRS 13 for determining fair value, (ii) assessing possible scientific indications for a change in the fair value and critically scrutinizing the assumptions made in this context, and (iii) reviewing information provided by the investments and publicly available information for possible indicators of a change in fair value. |
| ● | Utilizing personnel with specialized knowledge and skill of valuation techniques to assist in determining the appropriateness of the method used. |
We have served as the Company’s auditor since 2021.
/s/ BDO AG Wirtschaftsprüfungsgesellschaft
Berlin, Germany
April 14, 2025
F-4
Report of Independent Registered Public Accounting Firm
Shareholders and Supervisory Board
Evotec SE
Hamburg, Germany
Opinion on Internal Control over Financial Reporting
We have audited Evotec SE’s (the “Company’s”) internal control over financial reporting as of December 31, 2024, based on criteria established in Internal Control – Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission (the “COSO criteria”). In our opinion, the Company did not maintain, in all material respects, effective internal control over financial reporting as of December 31, 2024, based on the COSO criteria.
We do not express an opinion or any other form of assurance on management’s statements referring to any corrective actions taken by the Company after the date of management’s assessment.
We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated statements of financial position of Evotec SE as of December 31, 2024 and 2023, the related consolidated income statements and statements of comprehensive income, changes in stockholders’ equity, and cash flows for each of the three years in the period ended December 31, 2024, and the related notes (collectively referred to as “the consolidated financial statements”) and our report dated April 14, 2025 expressed an unqualified opinion thereon.
Basis for Opinion
The Company’s management is responsible for maintaining effective internal control over financial reporting and for its assessment of the effectiveness of internal control over financial reporting, included in the accompanying Item 15. Controls and Procedures. Our responsibility is to express an opinion on the Company’s internal control over financial reporting based on our audit. We are a public accounting firm registered with the PCAOB and are required to be independent with respect to the Company in accordance with U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.
We conducted our audit of internal control over financial reporting in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on the assessed risk. Our audit also included performing such other procedures as we considered necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion.
A material weakness is a deficiency, or a combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the company’s annual or interim financial statements will not be prevented or detected on a timely basis. As of December 31, 2024 Evotec SE did not maintain appropriately designed controls impacting the control environment, risk assessment procedures, and effective monitoring controls to prevent or detect material misstatements to the consolidated financial statements as identified and described in management’s assessment.
The material weaknesses identified relate to the lack of design and maintenance of effective controls over revenue recognition, over the review and approval of manual journal entries and over the accounting assessment of complex and non-standard accounting matters and associated presentation and disclosures.
These material weaknesses were considered in determining the nature, timing, and extent of audit tests applied in our audit of the 2024 consolidated financial statements, and this report does not affect our report dated April 14, 2025 on those consolidated financial statements.
F-5
Definition and Limitations of Internal Control over Financial Reporting
A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the financial statements.
Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.
/s/ BDO AG Wirtschaftsprüfungsgesellschaft
Berlin, Germany
April 14, 2025
F-6
Evotec Group -
Consolidated income statement for the years ended December 31, 2024, 2023 and 2022.
footnote | ||||||||
in k€ except share and per share data |
| reference |
| Year ended December 31, 2024 |
| Year ended December 31, 2023 |
| Year ended December 31, 2022 |
Revenue | 4 | |
| | | |||
Cost of Revenue |
| ( |
| ( | ( | |||
Gross profit |
| |
| | | |||
Operating income (expenses) |
|
| ||||||
Research and development | 5 | ( |
| ( | ( | |||
Selling, general and administrative | 5 | ( |
| ( | ( | |||
Other operating income | 5 | |
| | | |||
Other operating expenses | 5 | ( |
| ( | ( | |||
Impairments of intangible assets | 9 | — | ( | — | ||||
Reorganization costs | 5 | ( | — | — | ||||
Total operating income (expenses) |
| ( |
| ( | ( | |||
Operating income (loss) |
| ( |
| ( | | |||
Non-operating income (expense) |
|
|
| |||||
Gain (loss) on investment in financial instruments reevaluation | 10 | ( |
| ( | ( | |||
Share of profit (loss) and reevaluation of at-equity investments | 11 | ( |
| ( | ( | |||
Other financial income | 10 | | | | ||||
Other financial expense | 10 | ( | ( | ( | ||||
Other non-operating income (expense) | 10 | | ( | | ||||
Gain from Bargain Purchase | — | — | | |||||
Net Income (loss) before taxes |
| ( |
| ( | ( | |||
Income taxes | 6 | ( |
| ( | ( | |||
Net income (loss) |
| ( |
| ( | ( | |||
Weighted average shares outstanding |
| | | | ||||
Net income per share (basic) |
| ( | ( | ( | ||||
Net income per share (diluted) |
| ( | ( | ( |
See accompanying notes to consolidated financial statements.
F-7
Evotec SE and Subsidiaries -
Consolidated statement of comprehensive income for the years ended December 31, 2024, 2023 and 2022.
| footnote | Year ended |
| Year ended |
| Year ended | ||
in k€ | reference |
| December 31, 2024 |
| December 31, 2023 |
| December 31, 2022 | |
Net income (loss) |
|
| ( | ( | ( | |||
Accumulated other comprehensive income |
|
| ||||||
Items which are not re-classified to the income statement |
|
| ||||||
Remeasurement of defined benefit obligation |
| 12 | | ( | | |||
Revaluation of equity investments | 10 | ( | ( | ( | ||||
Taxes |
| 6 | ( | | ( | |||
Items which have to be re-classified to the income statement at a later date |
|
| ||||||
Foreign currency translation |
|
| | ( | ( | |||
Revaluation and disposal of other short-term investments |
|
| | | ( | |||
Taxes | | ( | — | |||||
Other comprehensive income (loss) |
|
| | | ( | |||
Total comprehensive income (loss) |
|
| ( | ( | ( |
See accompanying notes to consolidated financial statements.
F-8
Evotec SE and Subsidiaries -
Consolidated statement of financial position as of December 31, 2024 and December 31, 2023
| ||||||
in k€ |
| footnote reference |
| as of December 31, 2024 |
| as of December 31, 2023 |
Assets |
|
|
|
| ||
Current assets: |
|
|
|
| ||
Cash and cash equivalents |
| 10 | | | ||
Investments |
| 10 | | | ||
Trade and other receivables |
| 7 | | | ||
Contract assets | 4 | | | |||
Inventories |
| 7 | | | ||
Current tax assets |
| 6 | | | ||
Other current financial assets including derivatives |
| 10 | | | ||
Prepaid expenses and other current assets |
| 7 | | | ||
Total current assets |
| | | |||
Non-current assets: |
|
|
|
| ||
Non-current financial investments and other non-current financial assets | 10 | | | |||
Investments in associates and Joint ventures | 11 | | | |||
Property, plant and equipment |
| 8 | |
| | |
Intangible assets and Goodwill |
| 9 | |
| | |
Deferred tax assets |
| 6 | |
| | |
Non-current tax assets |
| 6 | |
| | |
Other non-current assets |
| |
| | ||
Total non-current assets | |
| | |||
Total assets | |
| |
F-9
| footnote | |||||
in k€ |
| reference |
| as of December 31, 2024 |
| as of December 31, 2023 |
Liabilities and Stockholders’ Equity | ||||||
Current liabilities: |
| |||||
Current financial liabilities | 10, 14 | | | |||
Trade and other payables | 7 | | | |||
Contract liabilities | 4 | | | |||
Deferred income | 7 | | | |||
Provisions | 12,13 | | | |||
Current income tax liabilities | | | ||||
Other current liabilities | 7 | | | |||
Total current liabilities | | | ||||
Non-current liabilities: | ||||||
Non-current financial liabilities | 10, 14 | | | |||
Deferred tax liabilities | 6 | | | |||
Provisions | 12,13 | | | |||
Contract liabilities | 4 | | | |||
Deferred income | 7 | | — | |||
Other non-current liabilities | | | ||||
Total non-current liabilities | | | ||||
Stockholders’ equity: | ||||||
Share capital | 12,16 | | | |||
Additional paid in capital | 12 | | | |||
Retained Earnings | ( | ( | ||||
Accumulated other comprehensive income | ( | ( | ||||
Total stockholders’ equity | | | ||||
Total liabilities and stockholders’ equity | | |
See accompanying notes to consolidated financial statements.
F-10
Evotec SE and Subsidiaries -
Consolidated statement of cash flows for the years ended December 31, 2024, 2023 and 2022.
footnote |
|
|
| |||||
in k€ |
| reference |
| 2024 |
| 2023 |
| 2022 |
Cash flows from operating activities |
| |||||||
Net income (Loss) |
| ( | ( | ( | ||||
Income tax expense | 6 | | | | ||||
Depreciation and amortization |
| 8, 9 | | | | |||
Impairment of tangible and intangible assets |
| 9 | | | — | |||
Equity settled share based payment transaction | 12 | | | | ||||
Financial income and expenses | 10 | | | | ||||
Share of loss (profit) and reevaluation of at-equity investments |
| 11 | | | | |||
Gain (loss) on investment in financial instruments reevaluation |
| 10 | | | | |||
Transactions costs and income related to acquisitions | — | — | ( | |||||
Other non-cash items** | | ( | ( | |||||
Loss on sale of investment of affiliated companies | 5,13 | | — | — | ||||
Changes in net working capital | 7 | ( | ( | | ||||
Taxes paid, net of refunds*** | 6 | | ( | ( | ||||
Net cash from operating activities |
| | | | ||||
Cash flows from investing activities |
| |||||||
Interest received | | | | |||||
Purchase of property, plant and equipment | 8 | ( | ( | ( | ||||
Proceeds from sale of property, plant and equipment |
| 8 | | | — | |||
Purchase of intangible assets and capitalization of development expenditures | 9 | ( | ( | — | ||||
Acquisition of subsidiaries net of cash acquired | — | | ( | |||||
Divestment of affiliated companies, net of cash disposed | 5,13 | ( | — | — | ||||
Purchase of investments in associated companies, other non-current investments and convertibles | 10, 11 | ( | ( | ( | ||||
Proceeds from divestment /sale of investments in associated companies, other non-current investments and convertibles | 10, 11 | | | — | ||||
Purchase of current investments | 10 | ( | ( | ( | ||||
Proceeds from sale of current investments | 10 | | | | ||||
Proceeds from government grants | | — | — | |||||
Net cash used in investing activities |
| ( | ( | ( | ||||
Cash flows from financing activities |
| |||||||
Interest paid | ( | ( | ( | |||||
Proceeds from capital increase |
| — | — | | ||||
Proceeds from loans |
| 10 | | | — | |||
Transaction costs related to loans | ( | — | — | |||||
Proceeds from the exercise of share options | 12 | | | | ||||
Repayments of loans |
| 10 | ( | ( | ( | |||
Repayments of lease liabilities |
| 10 | ( | ( | ( | |||
Net cash from financing activities |
| ( | | ( | ||||
Net increase (decrease) in cash equivalents |
| ( | | ( | ||||
Cash and cash equivalents at January 1 | | | | |||||
Effects of revaluation and of movements in exchange rates on cash held |
| | | ( | ||||
Cash and cash equivalents at December 31* |
| | | |
*
**
***
See accompanying notes to consolidated financial statements.
F-11
Evotec SE and Subsidiaries -
Consolidated statement of changes in stockholders’ equity for the years ended December 31, 2024, 2023, and 2022.
Income and expense recognised in | ||||||||||||||||
Share capital | other comprehensive income | |||||||||||||||
Additional | Foreign | Total | ||||||||||||||
footnote | paid-in | currency | Revaluation | Retained | stockholders’ | |||||||||||
in k€ except share data |
| reference |
| Shares |
| Amount |
| capital |
| translation |
| reserve |
| Earnings |
| equity |
Balance at January 1, 2022 |
| | | | ( | | ( | | ||||||||
Capital increase | — | — | — | — | — | — | — | |||||||||
Exercised stock options | 12 | | | — | — | — | — | | ||||||||
Stock option plan | 12 | — | — | | — | — | — | | ||||||||
Transaction costs | — | — | ( | — | — | — | ( | |||||||||
Deferred and current tax on future deductible expenses |
| — | — | — | — | — | ( | ( | ||||||||
Other comprehensive income | — | — | — | ( | ( | — | ( | |||||||||
Net income (loss) for the period | — | — | — | — | — | ( | ( | |||||||||
Total comprehensive income (loss) | — | — | — | ( | ( | ( | ( | |||||||||
Balance at December 31, 2022 | | | | ( | ( | ( | | |||||||||
Capital increase | — | — | — | — | — | — | — | |||||||||
Exercised stock options | 12 | | | — | — | — | — | | ||||||||
Stock option plan | 12 | — | — | | — | — | — | | ||||||||
Transaction costs |
| — | — | | — | — | — | | ||||||||
Deferred and current tax on future deductible expenses |
| — | — | — | — | — | — | — | ||||||||
Other comprehensive income | — | — | — | ( | | — | | |||||||||
Net income (loss) for the period | — | — | — | — | — | ( | ( | |||||||||
Total comprehensive income (loss) | — | — | — | ( | | ( | ( | |||||||||
Balance at December 31, 2023 | | | | ( | ( | ( | | |||||||||
Capital increase | — | — | — | — | — | — | — | |||||||||
Exercised stock options | 12 | | | — | — | — | — | | ||||||||
Stock option plan |
| 12 | — | — | | — | — | — | | |||||||
Transaction costs |
| — | — | — | — | — | — | — | ||||||||
Deferred and current tax on future deductible expenses |
| — | — | — | — | — | — | — | ||||||||
Other comprehensive income | — | — | — | | | — | | |||||||||
Net income (loss) for the period | — | — | — | — | — | ( | ( | |||||||||
Total comprehensive income (loss) | — | — | — | | | ( | ( | |||||||||
Balance at December 31, 2024 | | | | | ( | ( | | |||||||||
See accompanying notes to consolidated financial statements.
F-12
(1) Business description and basis of presentation
Evotec SE, including its affiliates and subsidiaries (“Evotec”, The “Group” or the “Company”), is a drug discovery and development company, continuously driving innovative approaches to develop new pharmaceutical products through discovery alliances and development partnerships with leading pharma and biotechnology companies as well as academic institutions, patient advocacy groups and venture capital partners.
Evotec SE, located in Hamburg (Essener Bogen 7, 22419 Hamburg, Germany) is registered in the Commercial Registry of Hamburg with HRB 156381.
The Company was founded on December 8, 1993, and is listed on the Frankfurt Stock Exchange (XETRA) since November 10, 1999, Segment Prime Standard, under the ticker “EVT“ as well as on NASDAQ, New York, USA under the trading symbol “EVO“ since November 8, 2021.
The Management Board prepared the consolidated financial statements for the financial year 2024 on April 14, 2025, and will subsequently submit them to the Supervisory Board for review and approval at a meeting on April 14, 2025. With reference to Section §264 (3) of the German Commercial Code, the subsidiary Evotec International GmbH does not prepare a management report (Section §289 of the German Commercial Code).
(2) Material accounting policies
The material accounting policies applied in the preparation of these Consolidated Financial Statements are set out below or in the respective note. These policies have been consistently applied to all the years presented, unless otherwise stated.
- Basis of preparation -
The consolidated financial statements cover the twelve-month periods ended December 31, 2024, 2023 and 2022.
In accordance with Regulation No. 1606/2002 of the European Parliament and Council of July 19, 2002 on the application of international accounting standards, Evotec has presented its consolidated financial statements in accordance with IFRS since 2005. The term “IFRS” refers collectively to international accounting and financial reporting standards (IASs and IFRSs) and to interpretations of the interpretations committees (SIC and IFRIC) with mandatory application as of January 1, 2024. The consolidated financial statements of Evotec as of December 31, 2024 have been prepared in compliance with IFRS as issued by the International Accounting Standards Board (IASB) and with IFRS as endorsed by the EU as of December 31, 2024.
Evotec SE, as the ultimate parent company, prepares its consolidated financial statements in its functional currency, the Euro. All amounts in the notes are stated in thousands of Euros (k€) unless otherwise noted. The Euro is the reporting currency of the Group. Due to rounding, amounts may not add up precisely to the totals provided.
The consolidated financial statements have been prepared in accordance with the IFRS general principles of fair presentation, going concern, accrual basis of accounting, consistency of presentation, materiality, and aggregation. The presentation of the consolidated income statement is based on the internal functions of the Group.
Additional requirements of Section §315e (1) of the German Commercial Code (HGB) have been applied in accordance with the version endorsed at the end of the reporting period.
- Significant accounting judgements and estimates-
The preparation of the Consolidated Financial Statements in accordance with IFRS requires management to make judgements, estimates and assumptions that affect the application of accounting policies, the reported amounts of assets, liabilities, revenues and expenses, the accompanying disclosures, as well as the disclosure of contingent liabilities. These estimates inherently contain a degree of uncertainty. Actual results may differ from these estimates under different assumptions or conditions.
F-13
The Group evaluates these accounting judgements and estimates on an ongoing basis and bases the estimates on historical experience, current and expected future outcomes, third-party valuation and various other assumptions that the Group believes are reasonable under the circumstances. Existing circumstances and assumptions about future developments may change due to circumstances beyond the Group’s control and are reflected in the assumptions if and when they occur.
The Group revises significant estimates as relevant and applicable if changes occur in circumstances or if new information or historical data is available and would require Evotec to do so.
The areas where the most significant judgements and estimates are made relate to the following areas:
Judgement:
| ● | Revenue recognition, determination of performance obligations and allocation of consideration as well as determination of advancement for over time performance obligations; |
| ● | Determination of the lease term and more specifically the assessment whether a lease option to extend or cancel a lease in which the Group is a lessee is reasonably certain to be exercised or not; |
| ● | Likelihood of occurrence of provisions, uncertain tax positions and contingent liabilities; |
| ● | Impairment analyses in relation with goodwill and intangible assets are performed annually as well as the determination of whether the carrying value exceeds the recoverable amount whenever a triggering event occurs. These analyses are generally based on estimates of discounted future cash flows; |
| ● | Determination of the fair values of Level 3 financial assets where significant inputs of the fair value measurement are not based on observable market data; |
| ● | Determination of marketing approval from regulatory authorities as a requirement for internally developed intangible capitalization; |
| ● | Determination of the recoverability of deferred tax assets; |
| ● | Identification of contingent liabilities and onerous contracts |
Estimates:
| ● | Assessment of the recoverable amount of goodwill and intangible assets; |
| ● | Measurement of the recoverability of deferred tax assets; |
| ● | Determination of fair values of acquired identifiable intangible assets as part of a business combination; |
| ● | Determination of budgeted FTE rates in the assessment of percentage of completion in relation with revenue recognition |
The Group considers the potential impact of climate related matters in estimates and assumptions, where appropriate, and monitors relevant changes and developments, including changes in legislation which may affect the fair value of financial assets and liabilities in the Consolidated Financial statements especially but not limited to deferred tax assets recoverability, useful life of tangibles and intangibles and provisions.
Even though climate-related matters increase the uncertainty in estimates and assumptions, as of December 31, 2024 the Group does not believe that the impact of climate related matters would be material to the Consolidated Financial Statements.
F-14
For further discussion of these significant judgements and estimates, reference is made to the respective Accounting Policies and Notes within these Consolidated Financial Statements that relate to the above topics.
- Basis of consolidation -
The Consolidated Financial Statements comprise the financial statements of Evotec SE and all the subsidiaries that the Company controls, i.e. when it is exposed or has rights to variable returns from its involvement with the investee and has the ability to affect those returns through its power over the investee. Generally, there is a presumption that a majority of voting rights results in control. To support this presumption and in cases where the Group has less than a majority of the voting or similar rights of an investee, the Group considers all relevant facts and circumstances in assessing whether it has power over an investee, including the contractual arrangement(s) with the other vote holders of the investee, rights arising from other contractual arrangements and the Group’s voting rights and potential voting rights.
Subsidiaries
Subsidiaries are fully consolidated from the date that control commences until the date that control ceases. Transactions between consolidated companies are eliminated, as well as intragroup profits.
Associates
Associates are all entities over which the Group has significant influence but no control. Significant influence is presumed with a shareholding between 20% and 50% of the voting rights or when the Group has board representation through which it is able to exercise significant influence, such as, but not limited to participating in the financial and operating policy decisions of that entity but does not have the power to exercise control or joint control over those policies. Investments in associates are accounted for using the at-equity method and are initially recognized at cost. Unrealized gains and losses from transactions between the Group and its associates or joint ventures are recognized only to the extent of unrelated investors` interests in the associates.
Loss of control
Upon loss of control, the Group derecognizes the assets and liabilities of the subsidiary, any non-controlling interests, and other components of equity (if any) related to the subsidiary. Any surplus or deficit arising from the loss of control is recognized in the Consolidated Income Statement. If the Group retains any interest in the previous subsidiary, such interest is measured at fair value at the date the control is lost. Subsequently, it is accounted for as either an equity accounted investee or as a financial asset depending on the level of influence retained.
All intercompany receivables, liabilities and all intercompany revenue, income, expenses and all intragroup profits or losses are eliminated in the consolidation.
The financial statements of all to be consolidated subsidiaries are prepared using the same reporting date as the consolidated financial statements (December 31).
- Foreign currencies -
Foreign currency transactions
The financial statements of all Evotec Group entities are measured using the currency of the primary economic environment in which the entity operates (“the functional currency”). The Euro (EUR) is the functional currency of the Group and the presentation currency of the Consolidated Financial Statements.
Foreign currency transactions are translated into the functional currency using the exchange rates prevailing at the dates of the transactions or the valuation in cases where items are remeasured. Foreign exchange gains and losses resulting from the settlement of such transactions and from the translation at year-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognized in the income statement.
F-15
Foreign operations
The assets and liabilities of foreign operations, including goodwill and fair value adjustments arising on acquisition, are translated to Euro at the exchange rates prevailing at the reporting date. The income and expenses of foreign operations are translated to Euros at the monthly average foreign exchange rate.
Foreign currency differences arising upon translation of foreign operations into Euros are recognized in Other Comprehensive Income and presented as part of currency translation reserves in Shareholders Equity. In the balance sheet these are recognized under retained earnings.
When a foreign operation is disposed of, leading to a loss of control, significant influence or joint control, the cumulative amount in the currency translation differences related to the foreign operation is reclassified to the Consolidated Income Statement as part of the gain or loss on disposal.
- Application of standards; amendments and interpretations-
The following amendments became effective as at January 1, 2024:
| ● | Amendments to IFRS 16 - Lease Liability in a Sale and Leaseback Transaction (January 1, 2024) |
| ● | Amendments to IAS 1 - Classification of Liabilities as Current or Non-current (including the amendment to IAS 1 - Classification of Liabilities as Current or Non-current - Deferral of Effective Date issued in July 2020) (January 1, 2024) |
| ● | Amendments to IAS 1 - Non-current Liabilities with Covenants (January 1, 2024) |
| ● | Amendments to IAS 7 and IFRS 7 - Supplier Finance Arrangements (January 1, 2024) |
None of those amendments had a significant impact on the Group’s consolidated financial statements for the 12 months period ended December 31, 2024.
The following amendments will become effective after January 1, 2025, however, may be early adopted:
| ● | Amendments to IAS 21 - Lack of Exchangeability (January 1, 2025) |
| ● | Amendments to IFRS 9 and IFRS 7 - Classification and Measurement of Financial Instruments (January 1, 2026) |
| ● | Amendments to IFRS 9 and IFRS 7 - Power Purchase Agreements (January 1, 2026) |
| ● | IFRS 18 - Presentation and Disclosures in Financial Statements (January 1, 2027) |
Evotec has not early adopted any new standards, interpretations or amendments that have been issued but are not yet effective in these consolidated financial statements.
IFRS 18 is expected to change the presentation of the Income statement and to differentiate between earnings from operating activities, investment activities and financing activities. IFRS 18 will also add additional disclosures but will not change any accounting policies on recognition and measurement, hence it will not change reported net results. Apart from that, none of those amendments are expected to have a significant impact on the Group´s consolidated financial statements.
F-16
(3) Segment information
In 2024, the Management Board made the decision to update the reportable segments to better steer the business and to reflect the underlying trends, evolutions and activities of the various business areas the Group is involved in. The Group believes that the
Shared R&D primarily includes drug discovery and development services and solutions. It starts with sourcing novel treatment ideas derived from patient data and continues with target validation and lead optimization. In the subsequent development phase selected candidates can seamlessly transition to Investigational New Drug ‘IND’ application.
Just – Evotec Biologics provides services related to designing, discovering, developing, and manufacturing of modern bio-therapeutics. Further Just – Evotec Biologics provides services in the areas of antibody molecular optimization, first-in-human integrated biologics, product and process design, continuous bioprocessing platforms, and commercial biomanufacturing.
Management does not allocate assets and liabilities to segments. The assessment of the individual operating segments is based on revenues and operating income (loss). Intersegment revenues are valued with a price comparable to other third-party revenues. Corporate activities are allocated based on internally defined allocation keys, primarily based on revenue.
The segment information for the financial year 2024 is as follows:
| Shared |
| Just - Evotec |
| Elimination between |
| Evotec | |
In k€ |
| R&D |
| Biologics |
| the segments |
| Group |
Revenues* |
| |
| |
| — |
| |
Intersegment revenues | | | ( | — | ||||
Cost of revenue | ( | ( | | ( | ||||
Gross profit | | | ( | | ||||
Operating income and (expenses) | ||||||||
Research and development cost | ( | ( | | ( | ||||
Selling, general and administrative cost | ( | ( | — | ( | ||||
Impairment/Reversal of impairment of intangible assets | — | — | — | — | ||||
Other operating income | | | — | | ||||
Other operating expenses | ( | ( | — | ( | ||||
Reorganization costs | ( | ( | — | ( | ||||
Total operating income and (expenses) | ( | ( | | ( | ||||
Operating income (loss) |
| ( |
| ( |
| — |
| ( |
*Includes Revenue from contributions of €
F-17
The segment information for the financial year 2023 is as follows:
Shared |
| Just - Evotec |
| Elimination between | Evotec | |||
In k€ |
| R&D |
| Biologics |
| the segments |
| Group |
Revenues* | | | — | | ||||
Intersegment revenues |
| — |
| — |
| — | — | |
Cost of revenue | ( | ( | — | ( | ||||
Gross profit | | ( | — | | ||||
Operating income and (expenses) | ||||||||
Research and development cost | ( | — | — | ( | ||||
Selling, general and administrative cost | ( | ( | — | ( | ||||
Impairment/Reversal of impairment of intangible assets | | ( | — | ( | ||||
Other operating income | | | — | | ||||
Other operating expenses | ( | ( | — | ( | ||||
Reorganization costs | — | — | — | — | ||||
Total operating income and (expenses) | ( | ( | — | ( | ||||
Operating income (loss) | ( | ( | — | ( |
*Includes Revenue from contributions of €
The segment information for the financial year 2022 is as follows:
| Shared |
| Just - Evotec |
| Elimination between |
| Evotec | |
In k€ |
| R&D |
| Biologics |
| the segments |
| Group |
Revenues* | | | — | | ||||
Intersegment revenues | — | — | — | — | ||||
Cost of revenue | ( | ( | — | ( | ||||
Gross profit | | ( | — | | ||||
Operating income and (expenses) | ||||||||
Research and development cost | ( | ( | — | ( | ||||
Selling, general and administrative cost | ( | ( | — | ( | ||||
Impairment/Reversal of impairment of intangible assets | — | — | — | — | ||||
Other operating income | | | — | | ||||
Other operating expenses | ( | — | — | ( | ||||
Reorganization costs | — | — | — | — | ||||
Total operating income and (expenses) | ( | ( | — | ( | ||||
Operating income (loss) | | ( | — | |
*Includes Revenue from contributions of €
F-18
- Geographical Breakdown-
The geographical breakdown of revenues from customers for the financial year 2024 is stated below:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues by region |
|
|
|
|
|
|
USA |
| |
| |
| |
Germany |
| |
| — |
| |
France |
| |
| — |
| |
United Kingdom |
| |
| |
| |
Switzerland |
| |
| |
| |
Rest of the world |
| |
| |
| |
Total revenue from contracts with customers | | | | |||
Revenue from contributions | | | | |||
Total Revenue |
| |
| |
| |
The geographical breakdown of revenues from customers for the financial year 2023 is stated below:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues by region |
|
|
|
|
|
|
USA |
| |
| |
| |
Germany |
| |
| |
| |
France |
| |
| — |
| |
United Kingdom |
| |
| — |
| |
Switzerland |
| |
| |
| |
Rest of the world |
| |
| — |
| |
Total revenue from contracts with customers | |
| |
| | |
Revenue from contributions | | | | |||
Total Revenue |
| |
| |
| |
The geographical breakdown of revenues from customers for the financial year 2022 is stated below:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues by region |
|
|
|
|
|
|
USA |
| |
| |
| |
Germany |
| |
| |
| |
France |
| |
| — |
| |
United Kingdom |
| |
| |
| |
Switzerland |
| |
| — |
| |
Rest of the world |
| |
| |
| |
Total revenue from contracts with customers | |
| |
| | |
Revenue from contributions | | | | |||
Total Revenue |
| |
| |
| |
F-19
Revenue is allocated to regions according to the location of the head office of the external customer.
Non-current assets categorized by the location of the companies as of December 31, 2024 and December 31, 2023 can be analyzed as follows:
in k€ |
| 2024 |
| 2023 |
USA |
| |
| |
United Kingdom |
| |
| |
Italy |
| |
| |
France |
| |
| |
Germany |
| |
| |
Austria |
| — |
| |
Total non-current assets |
| |
| |
Non-current assets shown in this table comprise of fixed assets, intangible assets, goodwill, non-current tax receivables, other non-current assets as well as investments for which the equity-method is applied.
(4) Revenue
-Accounting Principles-
Revenue from contracts with customers
Revenue is recognized when the control over separable goods, services or research services is transferred to the customer, provided that a contract with enforceable rights and obligations exists and that collectability of consideration is probable. The Group assesses collectability based on a number of factors, including past transaction history with the customer and the customer’s creditworthiness.
Multi-element contracts
The Group regularly enters into arrangements for the R&D and subsequent manufacture of product candidates. Such arrangements may require the Group to deliver various rights, services and/or goods, including intellectual property rights, licenses, technology access fee, R&D services, and manufacturing services. The underlying terms of these arrangements generally provide for consideration to the Group in the form of non-refundable upfront fees, development and R&D or commercial performance milestone payments, royalty payments or profit sharing.
In arrangements involving more than one performance obligation, each required performance obligation is evaluated to determine whether it qualifies as a distinct performance obligation based on whether:
| ● | the customer can benefit from the good or service either on its own or together with other resources that are readily available and |
| ● | the good or service is separately identifiable from other promises in the contract. |
The consideration under the arrangement is then allocated to each separate distinct performance obligation based on its respective relative stand-alone selling price. The estimated selling price of each deliverable reflects the Group´s best estimate of what the selling price would be if the deliverable was regularly sold by the Group on a stand-alone basis or by using an adjusted market assessment approach if the selling price on a stand-alone basis is not available.
F-20
The consideration allocated to each distinct performance obligation is recognized as revenue when control of the related goods or services is transferred. For performance obligations satisfied over time, the Group usually uses an FTE input-based method to determine the percentage of completion. In rare instances, the Group enters into performance obligations of providing a service of standing ready to provide goods or services.
Consideration associated with at-risk substantive performance milestones is recognized as revenue when it is highly probable that a significant reversal of the cumulative revenue recognized will not occur.
Material payments for those services are generally made in advance by the customer and recorded as contract liabilities until the related performance obligations are satisfied.
Contract assets are recognized in case the Group´s progress of completion of its performance obligations exceeds the amount of the payments received.
Milestone payments
Milestone payments for research and development are contingent upon the occurrence of a future event and represent a variable consideration. The Group usually estimates at contract’s inception that the most likely amount for milestone payments is zero. The most likely amount method of estimation is considered the most predictive for the outcome since the outcome is binary; e.g. achieving a specific success in clinical development (or not).
The Group includes milestone payments in the total transaction price only to the extent that it is highly probable that a significant reversal of revenue will not occur when the uncertainty associated with the variable consideration is subsequently resolved.
Service Fees
Service fees for the assignment of personnel to research and development collaborations are recognized as revenues in the period the services were provided.
Technology access fees
Revenue from technology access fees is recognized over the related service period. Payments for technology access fees are generally paid in full or in parts in advance and recorded as contract liabilities until earned.
Licenses of intellectual property
The Group distinguishes between the right to use IP and the right to access IP. Revenue for a right-to-use license is recognized by the Group when the licensee can use and benefit from the IP after the license term begins, e.g., the Group has no further obligations in the context of the out-licensing of a drug candidate or technology. In practice that means at the date of the sale or when the licensee gains effectively access.
Revenue from a right to access license of the intellectual property is recognized when the Group undertakes activities during the license term that significantly affect the IP, the customer is directly exposed to any positive or negative effects of these activities, and these activities do not result in the transfer of a good or service to the customer. Revenues from the right to access the IP are recognized on a straight-line basis over the license term.
Royalties
The Group receives royalties generated from successful development. Those royalties are generally sales based with additional milestones payments depending on the underlying market or product. The revenue generated from royalties is recognized as the underlying sales occur when it is highly probable that the consideration will be received.
F-21
Financing component and time value of money
The Group does not enter into arrangements where the period between the transfer of the promised goods or services to the customer and payment by the customer exceeds one year or the cash consideration and the stand alone selling price differs significantly. Additionally, the Group does not consider any prepayments provided by the customer as financing components. Consequently, the Group does not adjust any of the transaction prices for the time value of money.
Contract assets
Contract assets correspond to amounts accrued or due by customers for work in progress depending on the stage of completion of the analysis/work performed. The Group regularly assesses the state of its billing operations and the level of payer’s reimbursements based on specific facts and circumstances and historical recoverability data in order to identify issues which may impact the collection.
Contract liabilities
A contract liability is the obligation of the Group to transfer goods or services to a customer for which the Group has received a consideration (or an amount of consideration is due). If a customer pays the consideration before the Group transfers goods or services to the customer, a contract liability is recognized when the payment is made, or the payment is due (whichever is earlier). Contract liabilities are recognized as revenue when the Group fulfills its contractual obligation. The Group´s contracts do not include financing components as all up-front consideration received are prepayments on service obligations.
Revenue from contributions
Revenue Recognition from Contributions
The Group receives private contributions for which the existence of an adequate exchange transaction for research projects serving the public good is refuted. A realization of revenue from contracts with customers is not possible. A private contribution exists for which a contribution revenue item is recognized.
The effect on profit or loss is immediate or occurs over the period in which the subsidized service is provided. A liability item must be recognized for a contribution that has already been received, but this is not a contractual obligation, but rather other liability. The reversal of the liability item is gross, i.e., as contribution revenue separately from the revenues.
F-22
-Revenue-
The following schedule entails detailed information about the Group’s revenues in the financial year 2024:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues from contracts with customers |
|
|
|
|
|
|
Fee for service and FTE-based research payments |
| |
| |
| |
Recharges* |
| |
| — |
| |
Compound access fees |
| |
| — |
| |
Milestone fees |
| |
| — |
| |
Licenses |
| |
| — |
| |
Total revenue from contracts with customers |
| |
| |
| |
Timing of revenue recognition |
|
|
| |||
At a point in time |
| |
| |
| |
Over a period of time |
| |
| |
| |
Total revenue from contracts with customers | | | | |||
Revenue from contributions | | | | |||
Total Revenue |
| |
| |
| |
*
The following schedule entails detailed information about Group’s revenues in the financial year 2023:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues from contracts with customers |
|
|
|
|
|
|
Fee for service and FTE-based research payments |
| |
| |
| |
Recharges* |
| |
| — |
| |
Compound access fees |
| |
| — |
| |
Milestone fees |
| |
| — |
| |
Licenses |
| | |
| | |
Total revenue from contracts with customers |
| |
| |
| |
Timing of revenue recognition |
|
|
| |||
At a point in time |
| |
| |
| |
Over a period of time |
| |
| |
| |
Total revenue from contracts with customers | | | | |||
Revenue from contributions | | | | |||
Total Revenue |
| |
| |
| |
* Comprises of material re-charges to the customer
F-23
The following schedule entails detailed information about Group’s revenues in the financial year 2022:
Just - Evotec | ||||||
in k€ |
| Shared R&D |
| Biologics |
| Evotec Group |
Revenues from contracts with customers |
|
|
|
|
|
|
Fee for service and FTE-based research payments |
| |
| |
| |
Recharges* |
| |
| — |
| |
Compound access fees |
| |
| — |
| |
Milestone fees |
| |
| |
| |
Licenses |
| |
| |
| |
Total revenue from contracts with customers |
| |
| |
| |
Timing of revenue recognition |
|
|
| |||
At a point in time |
| |
| |
| |
Over a period of time |
| |
| |
| |
Total revenue from contracts with customers |
| |
| |
| |
Revenue from contributions | | | | |||
Total Revenue | | | |
* Comprises of material re-charges to the customer
The transaction prices allocated to the remaining performance obligation (unsatisfied or partially unsatisfied) are as follows:
in k€ |
| December 31, 2024 |
| December 31, 2023 |
| December 31, 2022 |
In the course of the year |
| | |
| | |
After one year |
| | |
| |
As of 2024, unsatisfied or partially unsatisfied performance obligations relating to contracts with a duration of one year or less, or that are billed based on time incurred, are not disclosed in the table above. As a result, 2024 figures are not directly comparable with 2023 and 2022 reported numbers.
During the year 2024 no material revenue was recognized from performance obligations that were already completely fulfilled in prior reporting periods.
In 2024,
In 2023 and 2022,
-Contract Assets-
In the course of the reporting year, contract assets changed as follows:
In k€ |
| 2024 |
| 2023 |
Balance as of January 1 |
| |
| |
Additions |
| |
| |
Reclassifications to Trade Receivables due to Invoicing |
| ( |
| ( |
Translation differences and other |
| |
| ( |
Balance as of December 31 |
| |
| |
F-24
As of December 31, 2024 and 2023,
-Contract Liabilities-
As of December 31, 2024 and 2023, current and non-current contract liabilities mainly originated from the upfront payments relating to the contracts with Group’s largest customer in the amount of €
| Current |
| Non-current | |||||
In k€ |
| 2024 |
| 2023 | 2024 |
| 2023 | |
Balance as of January 1 |
| |
| |
| |
| |
Additions |
| |
| |
| |
| — |
Reduction due to Recognition of Revenue |
| ( |
| ( |
| — |
| — |
Divestment of affiliates | ( | — | — | — | ||||
Reclassification from non-current to current |
| |
| |
| ( |
| ( |
Translation differences and other |
| |
| ( |
| — |
| — |
Balance as of December 31 |
| |
| |
| |
| |
(5) Other operating income (Loss)
-Accounting Principles-
Operating income excludes in general items that are not directly related to the Group’s operating activities, except cyber-related costs which are also included in the operating income. Activities in relation with the Group´s operating activities primarily relate to gains or losses on the disposal of material property, plant and equipment, gains or losses on the sale of Group companies, associates and joint ventures, indemnification provisions as well as disputes with minority shareholders.
Other Operating Income
The Group may receive tax credits from tax development programs in the context of qualifying R&D expenses in different jurisdictions. Such tax refunds regularly result in amounts which can be offset against taxable income, to provide a partial or full relief from tax or other payments to fiscal authorities. The Group determined that under its significant tax development programs, the feature of the credit is provided in a way which allows either offsetting against taxable income or instead, when insufficient taxable profits are available, direct reimbursement and payment in cash. In addition, the tax development programs are provided for specific activities, often limited to specific R&D expenses. As such, the Group accounts for such tax development programs as other operating income and does not account for such income as tax income or offsets tax credits from income tax expense.
In certain cases, the Group recharges indirect costs to third parties. The income from those recharges is recognized in other operating income when it is a direct reimbursement of costs. There is no underlying direct exchange of services for this income and therefore a recognition as revenues is not suitable. The relating expenses are recognized in other operating expenses as well as in R&D expenses.
Research and development
Research activities expenses undertaken with the prospect of gaining new scientific or technical knowledge and understanding are recognized in profit or loss when incurred. Refer to Note 9 for further details regarding the capitalization policy of IP R&D and other related expenses.
F-25
Government Grants
Government grants are recognized when all the conditions associated to those grants have been substantially complied with, and all attached conditions have been complied with. When the grant relates to an expense item, it is recognized as a reduction of the related expense. When the grant relates to an asset, it is recognized as income evenly over the expected useful life of the related asset.
Reorganization Costs
Reorganization costs include personnel costs related to termination benefits, site closure and contract termination costs, impairment losses recognized in accordance with IFRS 5 as well as other costs. Termination benefits are recognized when
| – | it is probable that employees will be entitled to benefits and |
| – | the amounts can be reasonably estimated. |
Estimates of termination benefits are based on negotiations with social partners, common practices in the industry, and the existence of statutory required minimum benefits. Site closure, contract termination and other costs are recognized when they are incurred. The impairment loss in accordance with IFRS 5 is based on the difference between the carrying amount of the disposal group, measured according to the applicable IFRSs until classification as held for sale, and the fair value less costs to sell. The specific restructuring measures and associated estimated costs are based on management’s best judgment under the existing circumstances at the time the estimates are made. If future events require changes to these estimates, such adjustments will be reflected in the period of the revised estimate.
- Personnel expenses -
The personnel expenses of the Group in 2024 amounted to €
- Cost of material-
Cost of materials in 2024 amounted to €
- Research and Development-
In 2024, research expenses mainly relate to internal R&D projects in the amount of €
-Selling, general and administrative expenses-
Included in selling, general and administrative expenses are expenses for sales and marketing in the amount of €
F-26
-Other operating income-
In 2024, other operating income included tax refunds for R&D activities (2024: €
-Other operating expense-
In 2024, other operating expense amounted to €
-Reorganization costs-
Reorganization costs amounted to €
(6) Income and deferred tax
-Accounting Principles-
Income taxes comprise current, non-current and deferred tax.
Income tax is recognized in the Consolidated Income Statement except to the extent that it relates to items recognized directly within equity or in Other Comprehensive Income.
Current tax is the expected taxes payable on the taxable income for the year, using tax rates enacted at the reporting date, and any adjustment to tax payable in respect of previous years. The tax rates for domestic companies are between
In cases where amounts recognized in the tax returns are likely not to be realized (uncertain tax positions), a tax liability is recorded. The amount is determined from the best possible estimate of expected tax payments (most likely amount of tax uncertainty). Tax claims from uncertain tax positions are only recognized if their realization is probable. Only in the case of an existing tax loss carryforward or an unused tax credit there is no tax liability or tax claim recognized for these uncertain tax positions; instead, the deferred tax asset for the unused tax loss carryforwards and tax credits is adjusted accordingly. This assessment relies on estimates and assumptions and may involve a series of judgements about future events.
New information may become available that causes the Group to change its judgement regarding adequacy of existing tax assets and liabilities. Such changes to tax assets and liabilities will impact the income tax expense in the period during which such a determination is made.
F-27
Deferred tax assets and liabilities are recognized, using the Balance Sheet method, for the expected tax consequences of temporary differences between the carrying amounts of assets and liabilities according to IFRS and the amounts used for taxation purposes. Deferred taxes are measured at the tax rates that are expected to be applied to temporary differences when they reverse, based on the laws that have been enacted or substantively enacted by the reporting date.
Deferred taxes are recognized for all taxable temporary differences, except:
| ● | temporary differences arising on the initial recognition of goodwill, |
| ● | temporary differences on the initial recognition of an asset or liability in a transaction that is not a business combination and, at the time of the transaction, affects neither the accounting profit nor taxable profit or loss, and at the time of the transaction, does not give rise to equal taxable and deductible temporary differences, |
| ● | temporary differences relating to investments in subsidiaries, associates, and interests in joint ventures, when the timing of the reversal of the temporary differences can be controlled and it is probable that the temporary differences will not reverse in the foreseeable future. |
Deferred tax assets and liabilities are offset if there is a legally enforceable right to offset current tax liabilities and assets, and they relate to income taxes levied by the same tax authority on the same taxable entity or on different taxable entities, but the Group intends to settle current tax liabilities and assets on a net basis or their tax assets and liabilities will be realized simultaneously.
A deferred tax asset is recognized for unused tax losses, tax credits and deductible temporary differences to the extent that it is probable that there will be future taxable profits against which they can be utilized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income in the countries where the deferred tax assets originated and during the periods when the deferred tax assets become deductible. The Group considers the scheduled reversal of deferred tax liabilities, projected future taxable income and tax planning strategies in making this assessment.
In 2024, deferred tax assets amounting to €
International Tax Reform - Pillar II Framework
The Group falls within the scope of application of the so-called Pillar II Framework, that entered into force in the German legislation on December 28, 2023.
The Minimum Tax Act applies for the first time financial years beginning on or after December 30, 2023 (“MinStG”). Pillar II legislation has been enacted or substantially enacted in a number of other jurisdictions in which the Group operates, effective for the financial year beginning January 1, 2024. As the Group is in scope of the Pillar II legislation the Group may be liable to pay a top-up tax for each jurisdiction having an effective tax rate below 15%.
During the transitional period from 2024 to 2026, the top-up tax can, upon request, be deemed zero for a jurisdiction where the requirements of the country by country reporting safe harbor rules are met. The Group will exercise this option, which based on the 2024 fiscal year, will lead to the Company being exempt from minimum taxation in most of the jurisdictions in which it operates.
The application of the global minimum tax rules, as implemented into domestic legislation of the jurisdictions in which the Group operates, results in no material minimum tax being recognized in 2024.
The Group has applied the exception to recognizing and disclosing information about deferred taxes relating to Pillar II income taxes, as provided by the amendment to IAS 12 issued in May 2023 and endorsed in the EU in November 2023.
F-28
-Income tax expenses-
Income tax benefit and expense for the years 2024, 2023 and 2022 comprise the following.
| 2024 |
| 2023 |
| 2022 | |
| k€ | k€ |
| k€ | ||
Current taxes |
|
|
|
| ||
- Tax expense for the year | ( | ( | ( | |||
- Income (expense) relating to other periods | | ( | | |||
Total current income taxes | ( | ( | ( | |||
Deferred taxes |
|
|
| |||
- Tax loss carry forwards | | | ( | |||
- Temporary differences | ( | | | |||
Total deferred income taxes | | | ( | |||
Tax income (expense) recognized in the income statement |
| ( | ( | ( |
-Reconciliation of effective tax rate-
The difference between the actual income tax expense and the result of the net income (loss) and the applicable Group tax rate in the reporting year and the previous year is made up as follows:
| 2024 |
| 2023 | 2022 |
| ||
| k€ |
| k€ | k€ |
| ||
Income (loss) before taxes | ( | ( |
| ( | |||
Expected German income tax rate | | % | | % | | % | |
Expected income tax benefit (expense) | | |
| | |||
Non-deductible expenses | ( | ( |
| ( | |||
R&D tax credits | | |
| | |||
Tax free income | | |
| | |||
Permanent differences from GILTI | ( | ( |
| ( | |||
Tax effects from investments accounted for using the equity method | ( | ( |
| ( | |||
Deviation tax rates to expected tax rate | ( | ( | | ||||
Change in tax rates | — | ( | | ||||
Change in recognition of deferred tax assets | ( | ( | ( | ||||
Taxes related to prior years |
|
|
| ||||
Current Taxes | | ( |
| | |||
Deferred Taxes | ( | |
| ( | |||
Other | | |
| ( | |||
Effective income tax income (expense) | ( | ( |
| ( | |||
Effective income tax rate | ( | % | ( | % | ( | % |
The Group tax rate includes corporate income tax plus solidarity surcharge of
The tax-free income in 2024 mainly results from the gain on the sale of the shares in Recursion Pharmaceuticals Inc and the non-deductible expenses mainly result from the devaluation of shares in corporations and the loss on the sale of the shares in Evotec Drug Substance GmbH.
F-29
-Deferred Taxes-
Deferred income tax assets and liabilities calculated with the anticipated tax rates of each entity as of December 31, 2024 and 2023 relate to the following:
Jan 1, 2024 | Dec 31, 2024 | |||||||||||||
Recognised in | ||||||||||||||
Recognised | other | Foreign | Deferred | Deferred | ||||||||||
in | comprehensive | currency | tax | tax | ||||||||||
Net balance | profit or loss | income | translation | Net | assets | liabilities | ||||||||
| k€ |
| k€ |
| k€ |
| k€ |
| k€ |
| k€ |
| k€ | |
Property, plant and equipment | ( | ( | — | | ( | | ( | |||||||
Intangible assets | ( | | — | — | | | ( | |||||||
Rights of use assets |
| ( |
| |
| — |
| — | ( |
| — |
| ( | |
Financial assets |
| ( |
| ( |
| |
| — | ( |
| |
| ( | |
Provisions and deferred income |
| |
| ( |
| ( |
| — | ( |
| |
| ( | |
Lease obligations |
| |
| ( |
| — |
| — | |
| |
| — | |
Other |
| |
| |
| |
| ( | |
| |
| ( | |
Tax credits |
| |
| ( |
| — | — | |
| |
| — | ||
Loss carryforward |
| |
| |
| — | — | |
| |
| — | ||
Total |
| ( |
| |
| |
| ( | |
| |
| ( | |
Offsetting of tax |
| — | — | — | — | — |
| ( |
| | ||||
Net |
| ( |
| |
| |
| ( | |
| |
| ( | |
Jan 1, 2023 | Recognised in | Dec 31, 2023 | ||||||||||||
Recognised | other | Foreign | Deferred | Deferred | ||||||||||
in | comprehensive | currency | tax | tax | ||||||||||
Net balance | profit or loss | income | translation | Net | assets | liabilities | ||||||||
| k€ |
| k€ |
| k€ |
| k€ |
| k€ |
| k€ |
| k€ | |
Property, plant and equipment | ( | ( | — | | ( | | ( | |||||||
Intangible assets | ( | | — | | ( | | ( | |||||||
Rights of use assets | ( |
| ( |
| — |
| — |
| ( |
| — |
| ( | |
Financial assets |
| ( |
| ( |
| ( |
| — |
| ( |
| |
| ( |
Provisions and deferred income |
| |
| ( |
| |
| — |
| |
| |
| ( |
Lease obligations |
| |
| ( |
| — |
| — |
| |
| |
| — |
Other |
| |
| |
| — |
| — |
| |
| |
| ( |
Tax credits |
| |
| |
| — | — |
| |
| |
| — | |
Loss carryforward |
| |
| |
| — |
| |
| |
| |
| — |
Total |
| ( |
| |
| ( |
| |
| ( |
| |
| ( |
Offsetting of tax |
| — | — | — | — | — |
| ( |
| | ||||
Net |
| ( |
| |
| ( |
| |
| ( |
| |
| ( |
-Unrecognized deferred tax liabilities-
Concerning undistributed foreign subsidiaries earnings, temporary differences in the amount of €
F-30
-Unrecognized deferred tax assets-
The Group’s deferred tax assets are recorded to the extent it is probable that such tax benefits would be realized in future years. As of December 31, 2024, deferred tax assets on tax loss carryforwards were not fully recognized for three German entities as well as one Italian entity and not recognized for the entities located in the United States, Austria and India. In the following schedule, tax loss carryforwards, interest carryforwards and tax credits for which no deferred tax assets were recorded are shown. Tax loss carryforwards on different types of income taxes were aggregated into one total amount.
| 2024 |
| 2023 |
| 2022 | |
| k€ | k€ |
| k€ | ||
Tax loss carryforwards (not expiring) | | |
| | ||
Time-limited tax losses | ||||||
- expiring until 2029 (2023: 2028) | | |
| | ||
- expiring 2030 to 2034 (2023: 2029 - 2033) | | |
| | ||
- expiring after 2034 (2023: 2033) | | |
| | ||
Tax credits | | |
| | ||
Total |
| | |
| |
The table above does not include U.S. tax losses which are subject to s382 restrictions.
In addition to unrecognized deferred tax assets from tax loss carryforwards, a net asset position for temporary differences amounting to €
-Non-current and current tax assets-
Non-current tax assets as of December 31, 2024 mainly relate to tax refunds from tax development programs in the context of qualifying R&D expenses in France (crédit d’impôt recherche) and Italy (December 31, 2023: mainly related to France).
Current tax assets as of December 31, 2024 mainly comprise of tax refunds in relation with qualifying R&D projects in in the UK, Italy and Germany (December 31, 2023: mainly related to UK).
(7) Current assets and liabilities
-Accounting Principles-
Trade accounts receivable
Trade accounts receivable are initially recognized at the transaction price in accordance with IFRS 15. For trade accounts receivable, the Group applies the simplified approach with expected lifetime credit losses recognized from initial recognition of the receivables in the income statement. The provision for doubtful debts is established using an expected credit loss model (ECL) using the simplified approach in accordance with IFRS 9. The carrying amount of trade accounts receivable is reduced through the use of an allowance account. Impaired trade accounts receivables are derecognized when they are assessed as uncollectible.
Inventories
In accordance with IAS 2, inventories are stated at the lower of cost or net realizable value. The cost of inventories comprises all costs of purchase, manufacturing, as well as other costs incurred in bringing the inventories to their present location and condition.
F-31
The cost of inventories is predominantly determined by using the weighted average cost method. Depending on the nature of inventory, the Group also applies the first-in, first-out method in rare cases. The net realizable value represents the estimated sales price in the ordinary course of business less the estimated costs of completion and the estimated costs necessary to make the sale. Write-downs of inventories which are considered obsolete or slow moving are computed taking into account their expected future utilization and their net realizable value. The Group also considers other reasons that the cost of inventories may not be recoverable such as damage, obsolescence, expiration date or declines in selling price.
-Trade accounts receivables-
Trade accounts receivables that were not individually impaired were classified as recoverable on the basis of credit management processes and individual assessments of customer risks. The valuation allowances include appropriate risk provisions. The Group has assessed the default risk of all trade accounts receivables. The resulting valuation allowance as of December 31, 2024 amounts to €
The maturities of trade receivables as at December 31, 2024 and December 31, 2023 taking into account risk provisions, are as follows:
| Dec 31 |
| Dec 31 |
| |
| 2024 |
| 2023 | ||
k€ | k€ |
| |||
Not past due | | |
| ||
Risk provision not past due |
| ( |
| ( | |
Weighted average loss rate | | % | | % | |
Past due 1-30 days |
| |
| | |
Risk provision 1-30 days |
| ( |
| ( | |
Weighted average loss rate | | % | | % | |
Past due 31-120 days |
| |
| | |
Risk provision 31-120 days |
| ( |
| ( | |
Weighted average loss rate | | % | | % | |
More than 120 days |
| |
| | |
Risk provision more than 120 days |
| ( |
| ( | |
Weighted average loss rate | | % | | % | |
Total trade accounts receivable |
| |
| |
F-32
The related loss allowances on trade accounts receivable have changed as follows:
| Credit-impaired |
| Lifetime expected |
| ||
Trade accounts receivable | credit losses | |||||
| (individually assessed) |
| (collectively assessed) |
| Total | |
k€ | k€ | k€ | ||||
Balance as of January 1, 2023 | | | | |||
Change in provision for ECL |
| — |
| ( |
| ( |
Additions/Reductions |
| |
| — |
| |
Recoveries collected |
| ( |
| — |
| ( |
Deductions from allowance |
| |
| — |
| |
Balance as of December 31, 2023 |
| |
| |
| |
Balance as of January 1, 2024 |
| |
| |
| |
Change in provision for ECL |
| — |
| |
| |
Additions/Reductions |
| |
| — |
| |
Recoveries collected |
| ( |
| — |
| ( |
Deductions from allowance |
| — |
| — |
| — |
Balance as of December 31, 2024 |
| |
| |
| |
-Inventories-
Inventories consist of the following:
| Dec 31 |
| Dec 31 | |
2024 | 2023 | |||
| k€ |
| k€ | |
Raw materials | | | ||
Work-in-progress | |
| | |
Total inventories | |
| |
Raw materials mainly consist of consumables, cell culture media and disposables. The increase compared to the previous year is mainly due to the growth in business activities in Just – Evotec Biologics.
The decrease in work-in-progress is due to the completion of projects in Aptuit Oxford as well as the disposal of Evotec DS.
Allowances on inventories exist at the balance sheet date in the amount of €
In 2024, €
-Prepaid expenses and other current assets-
Prepaid expenses as of December 31, 2024 mainly relate to prepayments for subscriptions to IT licenses. Other current assets mainly comprise VAT-related receivables of €
In k€ |
| December 31, 2024 |
| December 31, 2023 |
Prepaid expenses | | | ||
Other current assets |
| |
| |
Total prepaid expenses and other current assets |
| |
| |
F-33
-Trade payables-
As of December 31, 2024 the Group’s trade payables amounted to €
-Other current liabilities-
As of December 31, 2024 other current liabilities included wage taxes in the amount of €
-Deferred Income-
As of December 31, 2024, current and non-current deferred income amounted to €
(8) Property, plant and equipment
-Accounting principles-
Owned Assets
Property, plant and equipment, including leasehold improvements are recorded in the Statement of Financial Position at their acquisition price, net of accumulated depreciation and impairment losses.
The costs of property, plant and equipment comprise all directly attributable costs.
After initial measurement, property, plant and equipment is carried at cost less accumulated depreciation and impairment, except for land which is carried at cost less impairment.
Depreciation is calculated using the straight-line method over the estimated useful life of the asset, which the Group reviews at each balance sheet date. Costs related to repair and maintenance activities are expensed in the period in which they are incurred unless leading to an extension of the original lifetime or capacity. Leasehold improvements are amortized using the straight-line method over the shorter of the lease term or the estimated useful life of the asset.
Subsequent costs are not recognized as assets unless it is probable that future economic benefits associated with those costs will flow to the Group and those costs can be measured reliably. Borrowing costs attributable to the financing of items of property, plant and equipment, and incurred during the construction period, are capitalized as part of the acquisition cost of the item. Government grants relating to property, plant and equipment are recognized as income evenly over the expected useful life of the related asset.
The straight-line depreciation is based on the following useful lives of the asset:
Buildings |
| |
Technical equipment and machinery |
| |
Office furniture and equipment |
|
The costs included in property, plant and equipment related to assets under construction are not depreciated until the assets are placed into service by the Group. Upon sale or retirement, the costs and the related accumulated depreciation are removed from the respective accounts and any gain or loss is included in other operating income and expenses.
F-34
Leases
The Group leases various offices, laboratories equipment and cars. The Group determines whether an arrangement constitutes or contains a lease at inception, which is based on the substance of the arrangement. The arrangement constitutes or contains a lease if fulfillment is dependent on the use of a specific asset and the arrangement conveys a right to use the asset, even if that asset is not explicitly specified in the arrangement.
Leases are recognized as a right-of-use asset and a corresponding liability at the date at which the leased asset is available for use by the Group.
The right-of use asset is depreciated over the shorter of the asset’s useful life or the lease term on a straight-line basis.
Assets and liabilities arising from a lease are initially measured on a present value basis. Lease liabilities include the net present value of the following lease payments:
| ● | fixed payments (including in-substance fixed payments) less any lease incentives receivable; |
| ● | variable lease payments that are based on an index or a rate; |
| ● | amounts expected to be payable by the lessee under residual value guarantees; |
| ● | the exercise price of a purchase option if the lessee is reasonably certain to exercise that option; |
| ● | payments of penalties for terminating the lease, if the lease term reflects the lessee exercising that option. |
Variable lease payments that do not depend on an index or a rate are recognized as expenses in the period in which the event or condition that triggers the payment occurs.
The lease payments are discounted using the interest rate implicit in the lease. If that rate cannot be determined, the Group´s incremental borrowing rate at the lease commencement date is used, which is based on an assessment of interest rates, the Group would have to pay to borrow funds in the relevant country, including the consideration of factors such as the nature of the asset, its location, as well as the duration of the lease.
After the commencement date, the amount of lease liabilities is increased to reflect the accretion of interest and reduced for the lease payments made.
In addition, the carrying amount of lease liabilities is remeasured if there is a modification, a change in the lease term, a change in the in-substance fixed lease payments or a change in the assessment to purchase the underlying asset.
Right-of-use assets are measured at cost comprising the following:
| ● | the amount of the initial measurement of lease liability; |
| ● | any lease payments made at or before the commencement date less any lease incentives received; |
| ● | any initial direct costs; |
| ● | restoration costs. |
The right-of-use assets are subsequently accounted for using principles for property, plant and equipment.
F-35
Payments associated with short-term leases and leases of low-value assets are recognized on a straight-line basis as an expense in the income statement. The Group defines short-term leases as leases with a lease term of 12 months or less. Low-value assets comprise IT-equipment and small items of office furniture considered to be of low value (i.e., less than € 5,000).
The Group determines the lease term as the non-cancellable term of the lease, together with any periods covered by an option to extend the lease if it is reasonably certain to be exercised, or any periods covered by an option to terminate the lease, if it is reasonably certain not to be exercised. The Group applies judgement in evaluating whether it is reasonably certain to exercise the option to renew. That is, it considers all relevant factors that create an economic incentive for it to exercise the renewal.
-Property Plant and Equipment-
The development of property, plant and equipment as well as the development of the right-of-use assets in 2024 and 2023 are shown in the following tables:
Buildings and leasehold | Plant, machinery | Furniture | Assets under | |||||||||||||||
| improvements |
| and equipment |
| and fixtures |
| construction | Total | ||||||||||
in k€ |
| Owned |
| Right-of-Use |
| Owned |
| Right-of-Use |
| Owned |
| Right-of-Use |
| Owned |
| Owned |
| Right-of-Use |
Cost | | | | | | | | | | |||||||||
Accumulated depreciation and impairment |
| | | | | |
| |
| — | | | ||||||
January 1, 2024 |
| | | | | |
| |
| | | | ||||||
Recognition of right-of-use asset |
| — | | — | | — |
| |
| — | — | | ||||||
Capital expenditure/Additions |
| | — | | — | |
| — |
| | | — | ||||||
Disposals |
| | | | — | |
| |
| | | | ||||||
Depreciation |
| | | | | |
| |
| — | | | ||||||
Impairment |
| | | | | |
| |
| | | | ||||||
Reclassification |
| | | | ( | |
| — |
| ( | ( | ( | ||||||
Translation differences and other |
| | | | | |
| |
| | | | ||||||
Total |
| | | | | |
| |
| | | | ||||||
Cost |
| | | | | |
| |
| | | | ||||||
Accumulated depreciation and impairment |
| | | | | |
| |
| — | | | ||||||
December 31, 2024 |
| | | | | |
| |
| | | | ||||||
Buildings and leasehold | Plant, machinery and | Furniture | Assets under | |||||||||||||||
| improvements |
| equipment |
| and fixtures |
| construction |
| Total | |||||||||
in k€ |
| Owned |
| Right-of-Use |
| Owned |
| Right-of-Use |
| Owned |
| Right-of-Use |
| Owned |
| Owned |
| Right-of-Use |
Cost | | | | | | | | | | |||||||||
Accumulated depreciation and impairment | |
| |
| |
| |
| | | — |
| |
| | |||
January 1, 2023 | |
| |
| |
| |
| | | |
| |
| | |||
Recognition of right-of-use asset |
| — |
| |
| — |
| |
| — |
| |
| — |
| — |
| |
Capital expenditure/Additions |
| |
| — |
| |
| — |
| |
| — |
| |
| |
| — |
Disposals |
| |
| |
| |
| |
| |
| |
| — |
| |
| |
Depreciation |
| |
| |
| |
| |
| |
| |
| — |
| |
| |
Impairment |
| — |
| — |
| — |
| — |
| — |
| — |
| — |
| — |
| — |
Reclassification |
| |
| ( |
| |
| |
| |
| |
| ( |
| ( |
| |
Translation differences and other |
| ( |
| ( |
| ( |
| — | ( |
| |
| ( |
| ( |
| ( | |
Total |
| |
| |
| |
| |
| |
| |
| |
| |
| |
Cost |
| |
| |
| |
| |
| |
| |
| |
| |
| |
Accumulated depreciation and impairment | |
| |
| |
| |
| | | — |
| |
| | |||
December 31, 2023 |
| |
| |
| |
| |
| |
| |
| |
| |
| |
The net increase in the net book value of owned property, plant, and equipment of €
The decrease in the net book value of right-of-use assets (€
F-36
(9) Intangible assets and Goodwill
-Accounting principles-
Goodwill
The Group measures goodwill at the acquisition date as being the excess of:
| ● | Aggregate of the fair value of the consideration transferred and any recognized amount for non-controlling interests and any previous interest held, and |
| ● | the net identifiable assets acquired and liabilities assumed. |
If a preceding analysis of a purchase price allocation (PPA) results in the cost of acquisition being less than the fair value of the net assets of the subsidiary acquired, the difference is recognized directly in the Consolidated Income Statement (bargain purchase or negative goodwill).
Intangible Assets
Intangible assets with definite useful lives are recorded at cost and amortized using the straight-line method over the estimated useful lives of the assets.
Intangible assets other than goodwill with finite useful lives are tested for impairment whenever there is an indication that the asset may be impaired. If the recoverable amount of the asset is less than the carrying amount, an impairment loss is recognized. If the reason for a previously recognized impairment loss no longer exists, the impairment loss is reversed and the carrying amount of the asset is increased to its amortized cost.
Amortization of other intangible assets is recognized in the income statement within the relevant classification of expense by function.
Impairment losses are recognized separately in the Group´s income statement. The useful lives are as follows:
Trademarks |
| to |
Internally generated developed technologies |
| |
Acquired technologies | ||
Patents & licenses |
| |
Customer List |
|
Internally generated Development expenditures (IP R&D)
Internally generated development expenses are recognized as an intangible asset if and only if all the following criteria can be demonstrated:
| ● | technical feasibility of completing the project |
| ● | the Group´s intention to complete the project |
| ● | the Group´s ability to use the project |
| ● | the probability that the project will generate future economic benefits |
F-37
| ● | the availability of adequate technical, financial and other resources to complete the project |
| ● | the ability to measure the development expenditure reliably |
Due to the risks and uncertainties relating to regulatory approval and to the research and development process for pharmaceutical products, the six criteria for capitalization are usually considered not to have been met until the product has obtained marketing approval from the regulatory authorities. Consequently, internally generated development expenses arising before marketing approval has been obtained, mainly the cost of clinical trials, are generally expensed as incurred within research and development expenses.
Internally generated Development expenditures (other than IP R&D)
Capitalized development expenditures are stated at cost less accumulated amortization and impairment losses. Internally generated development expenses are recognized as an intangible asset if the criteria listed under “Internally generated Research and Development (IP R&D)” are met. They are amortized on a straight-line basis over the estimated useful lives of the intangible assets.
Separately acquired Research and Development (IP R&D)
Payments for separately acquired research and development are capitalized within other intangible assets provided that they meet the definition of an intangible asset:
| ● | expected to provide future economic benefits for the Evotec, |
| ● | a resource that is controlled by Evotec and, |
| ● | identifiable (i.e., it is either separable or arises from contractual or legal rights). |
The Group believes that the first condition for capitalization (the probability that the expected future economic benefits from the asset will flow to the entity) is considered to be satisfied for separately acquired research and development. Consequently, upfront and milestone payments to third parties related to pharmaceutical products for which marketing approval has not yet been obtained are recognized as intangible assets, and amortized on a straight-line basis over their useful lives beginning when marketing approval is obtained.
Payments under research and development arrangements relating to access to technology or to databases, and payments made to purchase generics dossiers, are also capitalized, and amortized over the useful life of the intangible asset. Subcontracting arrangements, payments for research and development services, and continuous payments under research and development collaborations which are unrelated to the outcome of that collaboration, are expensed over the service term.
Other intangible assets not acquired in a business combination
Licenses other than those related to pharmaceutical products and research projects, in particular software licenses, are capitalized at acquisition cost, including any directly attributable cost of preparing the software for its intended use. Software licenses are amortized on a straight-line basis over their useful lives.
Internally generated costs incurred to develop or upgrade software are capitalized if the recognition criteria are satisfied, and amortized on a straight-line basis over the useful life of the software from the date on which the software is ready for use.
Other intangible assets acquired in a business combination
Other intangible assets acquired in a business combination (R&D, technologies and technologies platforms, licenses and patents etc.) that are reliably measurable are identified separately from goodwill, measured at fair value, and capitalized within other intangible assets at the acquisition date and subsequently amortized over their useful lives.
F-38
Impairment
Goodwill
Goodwill is not amortized but is tested for impairment annually and whenever impairment indicators are identified. Internal or external sources of information are considered indicators that an asset or a Cash Generating Unit (CGU) or groups of CGUs may be impaired. An impairment loss is recognized in the Consolidated Income Statement whenever and to the extent that the carrying amount of a cash generating unit exceeds the unit’s recoverable amount. The recoverable amount is the higher of an asset’s fair value less costs to sell and its value in use.
Intangible Assets
Intangible assets that are subject to amortization are reviewed for impairment whenever triggering events or changes in circumstances indicate that the carrying value may not be recoverable. Additionally, intangible assets with an indefinite useful life and intangible assets that are not yet available for use (such as R&D projects) are tested annually for impairment.
-Goodwill-
As of January 1, 2024, Evotec changed its reporting structure leading to the reportable segments Shared R&D and Just – Evotec Biologics (see also note (3)). As the composition of CGUs to which goodwill has been allocated has changed, a reallocation of goodwill has been performed. The CGUs OAI/Evotec International Execute, OAI/Evotec International Innovate, Evotec (US) Execute and Aptuit Execute were combined into the new group of CGUs Shared R&D. The CGU Just Execute was renamed to Just – Evotec Biologics in line with the corresponding reportable segment.
Balances and movement of Goodwill in 2024 and 2023 are shown below:
2024 | ||||||||||||
Translation | ||||||||||||
in k€ |
| At January 1 |
| Acquisition |
| Disposals |
| Impairment |
| and other |
| At December 31 |
Shared R&D | | — | — | — | | | ||||||
Just - Evotec Biologics | | — | — | — | | | ||||||
Total |
| | — | — |
| — |
| |
| | ||
2023 | ||||||||||||
Translation | ||||||||||||
in k€ |
| At January 1 |
| Acquisition |
| Disposals |
| Impairment |
| and other |
| At December 31 |
OAI/Evotec International Execute | | — | — | — | | | ||||||
OAI/Evotec International Innovate | | | — | — | | | ||||||
Evotec (US) Execute | | — | — | — | ( | | ||||||
Aptuit Execute | | — | — | — | | | ||||||
Just Execute | | — | — | — | ( | | ||||||
Total | |
| |
| — |
| — |
| |
| | |
The goodwill addition in financial year 2023 to Shared R&D was a result of the acquisition of the remaining
The Group has tested the (groups of) cash-generating units for impairment on the annual designated test date in the fourth quarter 2024 based on the net book values as of September 30, 2024. The impairment tests are performed by determining the recoverable amount based on discounted cash flows.
F-39
In 2023, the impairment tests for all (groups of) cash-generating units were based on the value-in-use methodology. In 2024 the impairment tests for the (groups of) cash-generating units were performed based on the fair-value less costs to sell methodology in order to better align with internal planning procedures reflecting transformation and expansion plans. The impairment test in 2024 reflects a Level 3 approach according to the fair value hierarchy as defined in Footnote 15.
The estimated future cash flows for “Shared R&D” are based on the 2025 budget, followed by a
Due to the uncertainty inherent to the business and ongoing transformation efforts, the impairment tests for both (groups of) CGUs were performed by applying a scenario analysis with three different possible outcomes.
Management has identified the cash flow schedule, the terminal value growth rate, and the discount rate as key assumptions to which the recoverable amount is most sensitive.
Management has determined the values for the key assumptions as follows:
Cash flow
The cash flow plan is based on past experience and management’s expectations for the future, taking into account specific expectations regarding revenue and cost allocation, growth rates, gross margins, EBITDA margins and investments.
Long term growth rate
The terminal value growth rate is based on the current estimates of long-term inflation in the regions relevant to the Group’s operations.
Discount rate
The discount rates of the cash-generating units correspond to their weighted average cost of capital before tax, based on capital market data of a peer group
The following tables show the relevant pre-tax discount rate as well as the growth rates used to determine the terminal value in the respective discounted cash flow models in 2023 and 2024.
| 2024 | ||||
|
| Just - Evotec | |||
Shared R&D | Biologics | ||||
Denominated in |
| EUR / GBP |
| USD | |
Pre-tax discount rate |
| | % | | % |
Sustainable growth rate |
| | % | | % |
2023 | |||||||||||
OAI/Evotec | OAI/Evotec | Evotec | |||||||||
International | International | (US) | Aptuit | Just | |||||||
Execute | Innovate | Execute | Execute | Execute | |||||||
Denominated in |
| GBP /EUR |
| GBP /EUR |
| USD |
| GBP /EUR |
| USD | |
Pre-tax discount rate |
| | % | | % | | % | | % | | % |
Sustainable growth rate |
| | % | | % | | % | | % | | % |
F-40
In addition to the scenario - based approach, a sensitivity analysis was performed for both (groups of) cash-generating units with regard to reasonable changes in the key assumptions used for 2024. The analysis was based on a
In 2023, Management concluded that a change in the key assumptions for “Just Executes” could lead to an impairment. The following table shows which reasonably possible changes in the key assumptions for Just Execute would have caused the recoverable amount to be equal to its carrying amount in 2023.
2023 | ||||||||||||
Recoverable | Decrease in | Reduction | ||||||||||
amount exceeding | Applied post-tax | Increase in post-tax | Applied sustainable | sustainable | in cash | |||||||
| carrying amount |
| discount rate |
| discount rate |
| growth rate |
| growth rate |
| flows | |
| in €m |
| in %-points |
| in %-points |
| in %-points |
| in %-points |
| in %-points | |
Just Execute |
| |
|
|
|
|
| |||||
In 2024 and 2023, the Company did
-Intangible Assets-
The development of intangible assets in 2024 and 2023 is shown in the following tables.
2024 | ||||||||||
Patents and | Developed | Customer | ||||||||
In k€ |
| Licenses |
| Technologies* |
| relationships |
| Trademarks |
| Total |
Acquisition and manufacturing cost |
|
|
|
|
| |||||
Amount beginning of the year | | | | | | |||||
Foreign currency translation |
| ( | | | — | | ||||
Additions |
| — | | — | — | | ||||
Disposals |
| ( | — | — | — | ( | ||||
Reclassification | | | — | — | | |||||
Amount end of the year |
| | | | | | ||||
Depreciation, amortization and impairments |
| |||||||||
Amount beginning of the year |
| | | | | | ||||
Foreign currency translation |
| | | | — | | ||||
Additions |
| | | | | | ||||
Impairment | — | — | — | — | — | |||||
Disposals |
| ( | — | — | — | ( | ||||
Reclassification | — | — | — | — | — | |||||
Amount end of the year |
| | | | | | ||||
Net book value |
| |||||||||
Amount beginning of the year |
| | | | | | ||||
Amount end of the year |
| | | | | | ||||
*includes internally generated and acquired developed technologies
F-41
2023 | ||||||||||
| Patents |
| ||||||||
and | Developed |
| Customer |
|
| |||||
In k€ | Licenses | Technologies* | relationships | Trademarks | Total | |||||
Acquisition and manufacturing cost |
|
|
|
|
|
|
|
|
|
|
Amount beginning of the year |
| | | | | | ||||
Foreign currency translation |
| ( |
| ( |
| ( |
| — |
| ( |
Additions |
| — |
| |
| — |
| — |
| |
Disposals |
| — |
| — |
| — |
| — |
| — |
Reclassification | ( | | — | — | — | |||||
Amount end of the year |
| |
| |
| |
| |
| |
Depreciation, amortization and impairments |
|
|
|
|
|
|
|
|
|
|
Amount beginning of the year |
| |
| |
| |
| |
| |
Foreign currency translation |
| |
| ( |
| ( |
| — |
| ( |
Additions |
| |
| |
| |
| |
| |
Impairment | — | | — | — | | |||||
Disposals |
| — |
| — |
| — |
| — |
| — |
Reclassification | ( | | — | — | — | |||||
Amount end of the year |
| |
| |
| |
| |
| |
Net book value |
|
|
|
|
| |||||
Amount beginning of the year |
| |
| |
| |
| |
| |
Amount end of the year |
| |
| |
| |
| |
| |
*includes internally generated and acquired developed technologies
Intangible assets excluding goodwill increased by €
(10) Financial instruments
-Accounting principles-
Non-derivative financial assets
Non-derivative financial assets comprise cash and cash equivalents, receivables and other financial assets including derivatives.
Recognition and initial measurement:
Non-derivative financial assets are recognized when the Group becomes a party to the contractual provisions of the instrument.
Purchases and sales of non-derivative financial assets in the normal course of business are accounted for at the trade date.
Dividend and interest income are recognized when earned. Gains or losses, if any, are recorded in other financial income and other financial expense.
F-42
Non-derivative financial assets are derecognized when the rights to receive cash flows from the asset have expired or the Group has transferred its rights to receive cash flows from the asset. At initial recognition, the Group measures non-derivative financial assets at their fair value, plus, in the case of a financial asset not measured at fair value through profit or loss (FVtPL), transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets carried at FVtPL are expensed in the Consolidated Income Statement.
Classification and subsequent measurement:
The Group classifies its non-derivative financial assets in the following measurement categories:
| ● | those that are measured subsequently at fair value; |
| ● | those that are measured at amortized cost. |
In assessing the classification, the Group considers the business model for managing the financial assets and the contractual terms of the cash flows.
For assets measured at fair value, gains and losses will be recorded in either the Consolidated Income Statement (FVtPL) or in Other Comprehensive Income (FVtOCI).
For debt investments, assets are reclassified between FVtOCI, FVtPL and amortized cost only when its business model for managing those assets changes.
Offsetting of financial instruments
Financials assets and liabilities are only offset, and the net amount presented in the consolidated statement of financial position when, and only when, the Group has the legal right to offset the amounts and either to settle on a net basis or to realize the asset and settle the liability simultaneously.
Cash and cash equivalents
Cash and cash equivalents include cash balances, certain money market funds and short-term highly liquid investments with an original maturity of three months or less that are readily convertible into known amounts of cash.
Other financial assets
Other financial assets include convertible loans, derivatives and deposits.
Debt instruments
Debt instruments include those subsequently carried at amortized cost, those carried at FVtPL or those carried at FVtOCI.
Classification depends on the Group’s business model for managing the asset and the cash flow characteristics of the asset.
Debt instruments that are held for collection of contractual cash flows, where those cash flows represent solely payments of principal and interest, are measured at amortized cost and are subject to impairment. Interest income from these financial assets is included in Finance income using the effective interest rate method.
Financial assets with embedded derivatives are considered in their entirety when determining whether their cash flows are solely payment of principal and interest.
F-43
Debt instruments that are held for collection of contractual cash flows and for selling the financial assets, where the assets’ cash flows represent solely payments of principal and interest, are measured at FVtOCI and subject to impairment.
Movements in the carrying amounts are taken through OCI, except for the recognition of impairment gains or losses, interest revenue and foreign exchange gains and losses, which are recognized in the Consolidated Income Statement.
When the financial asset is derecognized, the cumulative gain or loss previously recognized in OCI is reclassified from equity to the Consolidated Income Statement. Interest income from these financial assets is included in financial income using the effective interest rate method. Debt instruments that do not meet the criteria for amortized cost or FVtOCI are measured at FVtPL. A gain or loss on a debt investment that is subsequently measured at FVtPL is recognized in the Consolidated Income Statement in the period in which it arises.
Other Equity investments where the Group does not possess control or significant influence
For those equity investments over which the Group has neither control nor significant influence and which are therefore measured in accordance with IFRS 9, classification will depend on whether the Group has made an irrevocable election at the time of initial recognition to account for the equity investment at fair value through other comprehensive income (FVtOCI).
For those equity investments over which the Group has neither control, joint control nor significant influence and which are therefore measured in accordance with IFRS 9, both FVtOCI and FVtPL, the Group follows the following hierarchy determined by the unique nature of the investments. Observable market prices are the primary method when available. When these are not available but there has been an external financing round or a capital transaction with a new investor of the equity investment in which the Group did not participate, this would be taken into account.
In the absence of such an event, the Group assesses qualitative factors, such as scientific progress, as well as an analysis of the cash position of the investment. In case of promising scientific development, the acquisition costs are considered to be the best estimate of the fair value. Should the investment be a possible going concern risk with no further positive qualitative factors, the Group uses Net Asset Value as a proxy for the fair value of the investment.
The investments in early-stage companies are mainly of a strategic nature and are made for the purpose of promoting new business models and, in particular, the development of products and/or technology platforms in pharmaceutical research.
Where the Group has elected to present fair value gains and losses on equity investments in OCI, there is no subsequent reclassification of fair value gains and losses to the Consolidated Income Statement following the derecognition of the investment. Dividends (if any) from such investments continue to be recognized in the Consolidated Income Statement when the Group’s right to receive payments is established.
Debt and other financial liabilities
Debt and other financial liabilities, excluding derivative financial liabilities and provisions, are initially measured at fair value and, in the case of debt and payables, net of directly attributable transaction costs. Debt and other financial liabilities are subsequently measured at amortized cost using the effective interest rate method. Amortized cost is calculated by taking into account any discount or premium on acquisition and fees or costs that are an integral part of the effective interest rate.
Debt and other financial liabilities are derecognized when the obligation under the liability is discharged, cancelled or has expired.
Derivative financial instruments
All derivative financial instruments are accounted for at the trade date and classified as current or non-current assets or liabilities based on the maturity date or the early termination date.
F-44
The Group measures all derivative financial instruments at fair value that is derived from the market prices of the instruments, calculated on the basis of the present value of the estimated future cash flows based on observable interest yield curves, basis spread, credit spreads and foreign exchange rates, or derived from option pricing models, as appropriate.
Gains or losses arising from changes in fair value of derivative financial instruments are recognized in the Consolidated Income Statement. The Group does not apply hedge accounting in accordance with IFRS 9 nor IAS 39.
Impairment of financial assets
The Group recognizes an allowance for expected credit losses (ECLs) for trade receivables, debt investments carried at fair value through other comprehensive income (FVtOCI) and amortized costs. ECLs are based on the difference between the contractual cash flows due in accordance with the contract and all the cash flows that the Group expects to receive.
For all trade receivables and contract assets, the Group applies the IFRS 9 simplified approach to measuring ECLs.
To measure the ECLs on trade receivables and contract assets, the Group takes into account credit-risk concentration, collective debt risk based on average historical losses as well as days past due.
The Group also may factor in specific circumstances such as serious adverse economic conditions in a specific country or region, and other forward-looking information.
The Group may also apply individual credit losses on identified trade account receivables or contract assets depending on individual circumstances.
Other financial income and expense
Financial income comprises interest income on funds invested (including financial assets), dividend income, net gains on the disposal of financial assets, net fair value gains on financial assets at FVtPL, net gains on the remeasurement to fair value of any pre-existing interest in an acquiree, and net gains on foreign exchange impacts that are recognized in the Consolidated Income Statement.
Other financial income is recognized on an accrual basis in the Consolidated Income Statement, using the effective interest method. Dividend income is recognized in the Consolidated Income Statement on the date that the Group’s right to receive payment is established, which in the case of quoted securities is normally the ex-dividend date.
Other financial expenses comprise interest expenses on borrowings, unwinding of the discount on provisions and contingent consideration, losses on disposal of financial assets, net fair value losses on financial assets at FVtPL, impairment losses recognized on financial assets (other than trade receivables), net interest expenses related to defined-benefit plans, interest on lease liabilities and net losses on foreign exchange impacts that are recognized in the Consolidated Income Statement.
Evotec’s interest expenses relate primarily to financial liabilities measured at amortized cost.
-Cash and cash equivalents and short-term investments-
The balances of cash and cash equivalents as of December 31, 2024 and December 31, 2023 are as follows:
In k€ |
| 2024 |
| 2023 |
Cash at banks and on hand |
| |
| |
Short term deposits |
| — |
| |
Money market funds |
| |
| |
Total |
| |
| |
F-45
As of December 31, 2024 the Group´s balance of cash and cash equivalents and investments is €
As of December 31, 2024, €
-Other current financial assets-
Other current financial assets (31 December 2024: €
-Other long term investments-
The development of investments measured at fair value in accordance with IFRS 9 is shown below:
In k€ |
| 2024 |
| 2023 |
Balance at January 1 |
| |
| |
Additions |
| |
| |
Additions due to discontinued use of equity method | — | | ||
Reduction due to change to accounting according to the equity method |
| — |
| ( |
Disposals | ( | — | ||
Fair value adjustments recognized in profit or loss | ( | ( | ||
Adjustments to fair value, recognized in OCI | ( | ( | ||
Balance at December 31 |
| |
| |
The loss of € (
Evotec periodically assesses the fair value of its investments and takes into account quantitative and qualitative information. Prior to the disposal of Evotec’s share in Recursion Pharmaceuticals Inc. (formerly known as Exscientia) (2024: €
F-46
-Loan Liabilities-
Throughout the years 2024 and 2023, the Group met all covenants under the various loan agreements shown below. All loans are unsecured, with the exception of loans in the amount €
December 31, | ||||||||||||||
2024 | 2024 | 2023 | 2023 | |||||||||||
Nominal interest | Maturity | Fair | Carrying | Fair | Carrying | |||||||||
Country of lender | Currency | Rate | until | Value | amount | Value | amount | |||||||
|
|
|
| k€ |
| k€ |
| k€ |
| k€ | ||||
Germany |
| EUR |
| fixed interest rate of |
| 2026-2029 |
| | |
| |
| | |
Germany |
| EUR |
| variable interest rate of |
| 2026 |
| | |
| |
| | |
Germany |
| EUR |
|
| 2025-2027 |
| | |
| |
| | ||
Germany | EUR | 2029 | | | | | ||||||||
Germany | EUR | 2031 | | | | | ||||||||
Italy | EUR | 2026 | | | | | ||||||||
Italy |
| EUR |
| variable interest rate of |
| 2027 |
| | |
| |
| | |
France |
| EUR |
| fixed interest rate of |
| 2026-2029 |
| | |
| |
| | |
| | |
| |
| | ||||||||
Current loan liabilities as of December 31, 2024 include interest liabilities of €
As of December 31, 2024, the Group maintained unutilized lines of credit totaling to €
-Leases-
The Group has lease contracts for various items of real estate, vehicles and other equipment used in its operations. The Group has multiple extension and termination options in a number of lease contracts. These are used to maximize operational flexibility in terms of managing the assets used in the Group’s operations. The options considered reasonably certain are part of lease liabilities. However, the options not considered reasonably certain are not part of lease liability, which exposes the Group to potential future cash outflows. Future cash outflows for leases that have not yet begun are set out in the explanation “(18) Commitments and contingencies”. In addition, the Group is not committed to leases not yet commenced. The Group’s lease contracts do not contain any financial covenants.
F-47
Set out below are the carrying amounts of the lease liabilities and the movements during the period:
In k€ |
| 2024 |
| 2023 |
Amount beginning of the year |
| |
| |
Foreign currency Translation |
| |
| ( |
Additions |
| |
| |
Divestment |
| ( |
| — |
Disposals |
| ( |
| ( |
Accretion of interest |
| |
| |
Payments |
| ( |
| ( |
Amount end of the year |
| |
| |
The lease liabilities of the Company are due as follows:
In k€ |
| 2024 | 2023 | |
Current portion of lease obligations | |
| | |
Long-term lease obligations | |
| | |
| |
| |
Lease liabilities are classified within Current financial liabilities and Non-current financial liabilities on the Consolidated statement of financial position. The Group’s cash outflows for leases amounted to €
The following amounts are recognized in profit or loss:
in k€ |
| 2024 |
| 2023 |
| 2022 |
Depreciation expense of right-of-use assets |
| | |
| | |
Interest expense on lease liability |
| | |
| | |
Expense relating to short-term leases |
| | |
| | |
Expense for leases on an asset of low value |
| | |
| | |
Total amount recognised in profit or loss |
| | |
| |
F-48
-Reconciliation of cash flow from financing activities-
The following tables show the reconciliation of cash flow from financing activities to changes in financial liabilities in 2024 and 2023.
| Loans |
| Lease Obligations | |
k€ | k€ | |||
Balance as of January 1, 2024 |
| |
| |
Proceeds from issuance of loans |
| |
| — |
Repayments |
| ( |
| ( |
Interest Paid | ( | — | ||
Cash flow from financing activities |
| ( |
| ( |
Non-cash transactions: |
|
| ||
Disposal of finance lease obligation |
| — |
| ( |
Foreign currency translation |
| — |
| |
Divestment of affiliates | — | ( | ||
Reclassification1) | ( | — | ||
Interest expense | | | ||
Change in accrued interest and other | — | — | ||
Issue of finance lease obligation |
| — |
| |
Balance as of December 31, 2024 |
| |
| |
1) Reclassed into non-current deferred income as Evotec has met terms to qualify for loan forgiveness.
| Loans |
| Lease Obligations | |
k€ | k€ | |||
Balance as of January 1, 2023 |
| |
| |
Proceeds from issuance of loans |
| |
| — |
Repayments |
| ( |
| ( |
Interest Paid | ( | — | ||
Cash flow from financing activities |
| |
| ( |
Disposal of finance lease obligation |
| — |
| ( |
Foreign currency translation |
| — |
| ( |
Divestment of affiliates | — | — | ||
Reclassification | — | — | ||
Interest expense | | — | ||
Change in accrued interest and other | | | ||
Issue of finance lease obligation |
| — |
| |
Balance as of December 31, 2023 |
| |
| |
-Current financial liabilities-
As of December 31, 2024, current financial liabilities amounted to €
F-49
(11) Investments accounted for using the equity method
-Accounting Principles-
The Group, in the course of its business, may enter into arrangements where it will exercise joint control over entities resulting in classifying these operations as joint ventures or joint operations depending on the rights and obligations arising from the contractual arrangement.
Alternatively, it may enter into arrangements where it holds 20 to 50 percent of the voting rights and exercises significant influence resulting in these companies being classified as associate companies.
Investments in associates and joint ventures are accounted for using the equity method.
The Group’s share of profit of joint ventures is classified within non-operating profit as these operations do not form an integral part of the Group’s financial performance, reflecting its non-core business activities.
The Group’s share of profit (loss) of associates is classified below Operating profit.
Goodwill arising from an acquisition is included in the carrying amount of the investments in joint ventures and associated companies.
Equity accounting is discontinued when the carrying amount of the investment together with any long-term interest in a joint venture or in an associate reaches zero, unless the Group has either incurred or guaranteed additional obligations in respect of the joint venture or associate.
Impairment of Joint Ventures and Associates
The Group tests investments in joint ventures and associates for which it does not possess control, but has significant influence for impairment on a regular basis and when there is objective evidence of impairment as a result of one or more events that occurred after the initial recognition of the net investment.
Objective evidence of impairment includes but is not limited to the net asset value being below carrying amount, absence of scientific progress, significant financial difficulties of the joint venture, associate or information about significant changes with an adverse effect that have taken place in the economic environment in which it operates and indicates that the carrying amount may not be recovered.
-Investment in associates-
Individually immaterial shares in companies accounted for using the equity method are presented in aggregate, provided that at the balance sheet date the equity book value did not exceed €
The additions to the significant investments in 2024 are entirely related to financing rounds (capital contributions).
F-50
The following table summarizes the development of the investments in associates during year 2024:
Centauri | Quantro | Topas | ||||||||||||
Autobahn | Therapeutics | EIR | Therapeutics | Therapeutics | Insignificant | |||||||||
In k€ |
| Labs LLC |
| Ltd. |
| Biotherapies |
| GmbH |
| GmbH |
| investments |
| Total |
Balance at January 1, 2024 | — | |
| — |
| | — | — |
| | ||||
Investment | | — | | — | | | | |||||||
Share of profit/(loss) in associate | ( | ( | ( | ( | ( | — | ( | |||||||
Impairment | — | — | — | — | — | — | — | |||||||
Dividends earned, Divestment or Reclassification |
| — | — | — | — | — | — | — | ||||||
Balance at December 31, 2024 |
| — | |
| |
| — | — | |
| |
The following table provides an overview of the development of the investments in 2023:
|
| Centauri |
|
| Dark Blue | Topas | Tucana |
|
| |||||||
Autobahn | Therapeutics | Curexsys | Therapeutics | Therapeutics | Bioscienes | Insignificant | ||||||||||
In k€ |
| Labs LLC |
| Ltd. |
| GmbH |
| Ltd. |
| GmbH |
| Inc. |
| investments |
| Total |
Balance at January 1, 2023 | |
| — |
| |
| | | | |
| | ||||
Investment | | | — | — | | — | — | | ||||||||
Share of profit/(loss) in associate |
| ( | ( | ( | ( | ( | ( | ( | ( | |||||||
Impairment |
| — | ( | ( | — | — | ( | ( | ( | |||||||
Dividends earned, Divestment or Reclassification | — | |
| — |
| — | — | ( | ( |
| ( | |||||
Balance at December 31, 2023 | — |
| |
| — |
| — | — | — | |
| |
Further financial information on the significant investments accounted for using the equity method is presented below:
2024
Centauri | Dark Blue | Quantro | Topas | |||||||
Therapeutics | Therapeutics | EIR | Therapeutics | Therapeutics | ||||||
In k€ |
| Ltd |
| Ltd |
| Biotherapies |
| GmbH |
| GmbH |
Current assets |
| |
| | | |
| | ||
Non-current assets |
| |
| | | |
| | ||
Current liabilities |
| |
| | | |
| | ||
Non-current liabilities |
| — |
| — | | |
| — | ||
Revenues from 1 Jan to 31 Dec | | — | — | | — | |||||
Net income (loss) 1 Jan to 31 Dec |
| ( |
| ( | ( | ( |
| ( |
2023
Centauri | Dark Blue | Quantro | ||||||||
Autobahn | Therapeutics | Curexsys | Therapeutics | Therapeutics | ||||||
In k€ |
| Labs LLC |
| GmbH |
| GmbH |
| Ltd. |
| GmbH |
Current assets | | | | | | |||||
Non-current assets |
| |
| — |
| |
| |
| |
Current liabilities |
| |
| — |
| |
| |
| |
Non-current liabilities |
| — |
| — |
| — |
| |
| |
Revenues from 1 Jan to 31 Dec | — | | — | — | | |||||
Net income (loss) 1 Jan to 31 Dec |
| ( |
| ( |
| ( |
| ( |
| ( |
F-51
(12) Employment, Post-Employment Benefits and Share Compensation Plans
-Accounting Principles-
Short-term employee benefits
Short-term employment obligations are measured on an undiscounted basis and are expensed as the related service is provided. The Group recognizes a liability and an expense for bonuses and incentives based on a formula that takes into consideration the profit attributable to the Group´s shareholders after certain adjustments.
Defined contributions schemes
A defined-contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and will have no legal or constructive obligation to pay further amounts. Obligations for contributions to defined-contribution pension plans are recognized as an employee benefit expense in the income statement in the periods during which services are rendered by employees. The Group´s contribution rate is employee-specific and depends on the amount of an employee’s contribution and the relevant legislation.
Defined benefits schemes and Jubilee provisions
A defined-benefit plan is a post-employment benefit plan other than a defined-contribution plan. Plans for which the Group has no legal or constructive obligation to pay further amounts, but to which it does pay non-fixed contributions, are also treated as a defined-benefit plan.
The net pension asset or liability recognized in the consolidated statement of financial position in respect of defined-benefit post-employment plans is the fair value of plan assets less the present value of the projected defined-benefit obligation at the balance sheet date.
The defined-benefit obligation is calculated annually by qualified actuaries using the projected unit credit method. Recognized assets are limited to the present value of any reductions in future contribution or any future refunds.
The net pension liability (asset) is presented as a long-term provision; no distinction is made for the short-term portion. Pension costs in respect of defined-benefit post-employment plans primarily represent the increase of the actuarial present value of the obligation for post-employment benefits based on employee service during the year and the interest on the net recognized asset or liability in respect of employee service in previous years. Remeasurements of the net defined-benefit asset or liability comprise actuarial gains and losses, the return on plan assets (excluding interest) and the effect of the asset ceiling (excluding interest). The Group recognizes all remeasurements in other comprehensive income and reclassifies them later to the Group´s income statement.
The Group recognizes gains and losses on the settlement of a defined-benefit plan when the settlement occurs. The gain or loss on settlement is the difference between the present value of the defined-benefit obligation being settled, as determined on the date of settlement, and the settlement price, including any plan assets transferred and any payments made directly by the Group in connection with the settlement. Past service costs arising from the introduction of a change to the benefit payable under a plan or a significant reduction of the number of employees covered by a plan (curtailment) are recognized in full in the consolidated income statement.
The Group´s net obligation in respect of long-term employee benefits is the amount of future benefit that employees have earned in return for their service in the current and prior periods, such as jubilee entitlements. That benefit is discounted to determine its present value. Remeasurements are recognized in the consolidated income statement in the period in which they arise.
Other long term employment benefits
Other long-term employment benefits include long-service leave or sabbatical leave, medical aid, jubilee or other long-service benefits, long-term disability benefits and, if they are not expected to be settled wholly within twelve months after the year end, profit sharing, variable and deferred compensation. The measurement of these obligations differs from defined benefit plans in that all remeasurements are recognized immediately in the statement of income.
F-52
Stock Options and SPAs
The Group operates various equity-settled share-based compensation plans for which the Company applies the regulations of IFRS 2. The fair value of the employee services received in exchange for the grant of the options or shares is recognized as an expense. The total amount to be expensed is determined by reference to the fair value of the equity instruments granted. The amounts are charged to the income statement over the relevant vesting periods and adjusted to reflect actual and expected levels of vesting. The cost of equity-settled transactions is determined by the fair value at the date when the grant is made using an appropriate valuation model.
All plans are settled in shares. The grant-date fair value of equity-settled share-based payment awards granted to employees is recognized as personnel expense, with a corresponding increase in equity, over the vesting period of the award.
The cumulative expense recognized for equity-settled transactions at each reporting date until the vesting date reflects the extent to which the vesting period has expired and the Group’s best estimate of the number of equity instruments that will ultimately vest.
The expense or income in the consolidated income statement for a period represents the movement in cumulative expense recognized at the beginning and end of that period. Service and non-market performance conditions are not taken into account when determining the grant-date fair value of awards, but the likelihood of the conditions being met is assessed as part of the Group´s best estimate of the number of equity instruments that will ultimately vest. Market performance conditions are reflected within the grant-date fair value.
No expense is recognized for awards that do not ultimately vest because non-market performance and/or service conditions have not been met.
When an award is cancelled by the entity or by the counterparty, any remaining element of the fair value of the award is expensed immediately through profit or loss. The dilutive effect of outstanding options and shares is reflected as additional share dilution in the computation of diluted earnings per share.
-Defined contribution schemes-
The Group operates a defined contribution plan in the United Kingdom and makes additional contributions to employees’ own schemes. The pension charge for the year represents contributions payable by the Group to the fund (and to the employees’ own pension schemes) and amounted to €
The Group operates defined contribution (401(k)) plans in the US and made contributions of €
-Defined benefit schemes and jubilee provision-
Germany
As of December 31, 2024, the Group’s defined benefit obligations in Germany amounted to €
France
The Group runs a jubilee scheme where a lump sum payment is provided to all employees upon retirement. The amount is dependent on different factors such as years of service with the company, compensation at retirement age (between age of
The Group also runs a work anniversary awards agreement. The lump sum amount is defined by the collective agreement and based on the number of years of service with the Group.
F-53
The Group operates a defined benefit plan for employees in France. The mortality tables (issued by INSEE TD/TV 2017 ‐ 2019 for 2023 and INSEE TD/TV 2018 – 2020 for 2024) were applied in the actuarial report that is used for measuring the French employee benefit obligations.
The movement in employee benefit obligations of the French entities is broken down as follows:
| 2024 |
| 2023 | |
In k€ | Present | Present | ||
value of | value of | |||
| obligation |
| obligation | |
As of January 1 |
| ( |
| ( |
Benefit payments from the employer |
| |
| |
Current service cost |
| ( |
| ( |
Past service costs |
| — |
| |
Effect of curtailment | | — | ||
Operating costs, net |
| |
| ( |
Interest expense (income) |
| ( |
| ( |
Amount recognized in the Income Statement |
| ( |
| ( |
Remeasurements: |
|
|
|
|
(Gain)/loss from change in demographic assumptions |
| |
| ( |
(Gain)/loss from change in financial assumptions |
| |
| ( |
(Gain)/loss from experience |
| ( |
| ( |
Thereof - Amounts recognized in the Income Statement | | — | ||
Thereof - Amounts recognized in Other Comprehensive Income |
| |
| ( |
As of December 31 |
| ( |
| ( |
The following table shows the significant assumptions which have been applied in the measurement of the employee benefit obligations:
Discount Rate | Salary Increase | ||||||||
| 2024 |
| 2023 |
| 2024 |
| 2023 | ||
France |
| | % | | % | | % | | % |
If the below parameters would increase/decrease by 0.5%, the benefit obligations would change as follows:
| 2024 |
| 2023 | |||||
Increase | Decrease | Increase | Decrease | |||||
+ | k€ | k€ | k€ | k€ | ||||
Discount rate |
| ( |
| |
| |
| ( |
Salary increase |
| |
| ( |
| ( |
| |
The average duration of the pension plan is
Expenses for the statutory retirement obligations are explained in Note (5).
F-54
-Share Compensation Plans-
In order to continue to incentivize executives in the form of variable compensation components with long-term incentives, in June 2022, June 2020 and June 2017, the AGM approved the respective conditional capital required for the so-called Restricted Share Plan 2020 (“RSP 2020”) as well as the so-called Share Performance Plan 2022 (“SPP 2022”) and Share Performance Plan 2017 (“SPP 2017”). Under these plans, Restricted Share Awards (“RSA”) for up to
SPAs from SPP 2022 and SPP 2017 will be automatically exercised within trading days after the end of the
RSAs under RSP 2020 may only be exercised if and to the extent that the performance target is achieved within each of the
SPAs from SPP 2022 and SPP 2017 can only be exercised if and to the extent that
On February 14, 2023, Evotec’s Management Board approved the U.S. Restricted Share Unit Plan (“U.S. RSU Plan”). The U.S. RSU Plan became effective May 31, 2023. The U.S. RSU Plan provides for the grant of restricted share units, which payment may be granted in the form of shares, American depository shares, each representing -half of one Evotec SE ordinary share (ADSs), or cash amounts as the Management Board determines to be consistent with best interests of the Company, Evotec and its shareholders and in accordance with the purpose of the U.S. RSU Plan. The Group accounts for the U.S RSU Plan as settled in shares. The number of restricted share units granted in the 12 months period ended December 31, 2024 totaled
F-55
A summary of the status of the Share Performance and Restricted Share Plans as of December 31, 2024, 2023, 2022 and the respective changes during the year is presented as follows:
| December 31 | |||||||||||
2024 | 2024 | 2023 | 2023 | 2022 | 2022 | |||||||
Weighted | Weighted | Weighted | ||||||||||
Share | average | Share | average | Share | average | |||||||
in k€ |
| Awards |
| exercise price |
| Awards |
| exercise price |
| Awards |
| exercise price |
in thousands | in € per share | in thousands | in € per share | in thousands | in € per share | |||||||
Granted SPAs/RSAs at the beginning of the year | | | | | | | ||||||
SPAs/RSAs granted | | | | | | | ||||||
Adjustment based upon KPI target achievement | | | | | — | | ||||||
Exercised SPAs/RSAs | ( | | ( | | ( | | ||||||
Forfeited SPAs/RSAs | ( | | ( | | ( | | ||||||
Expired SPAs/RSAs |
| ( |
| |
| — |
| | — | | ||
SPAs/RSAs granted at the end of the year |
| |
| |
| |
| | | | ||
Thereof exercisable |
| — |
| |
| — |
| | — | | ||
The SPAs in this table include RSPs and SSPs, prior year’s numbers included RSUs that are presented separately in the table below. Prior year numbers were adjusted accordingly.
Evotec’s average weighted share price at the exercise day of SPAs in financial year 2024 was €
A summary of the status of the Restricted Share Unit Plans as of December 31, 2024, 2023, 2022 and the respective changes during the year is presented as follows:
| December 31 | |||||||||||
| 2024 |
| 2024 |
| 2023 |
| 2023 |
| 2022 |
| 2022 | |
| Weighted |
| Weighted |
| Weighted | |||||||
| Restricted |
| average |
| Restricted |
| average |
| Restricted |
| average | |
| Share Units |
| exercise |
| Share Units |
| exercise |
| Share Units |
| exercise | |
| (RSUs) |
| price |
| (RSUs) |
| price |
| (RSUs) |
| price | |
| in € per |
| in € per |
| in € per | |||||||
| in thousands |
| share |
| in thousands |
| share |
| in thousands |
| share | |
Granted RSUs at the beginning of the year |
| |
| — |
| — |
| — |
| — |
| — |
RSUs granted |
| |
| — |
| |
| — |
| — |
| — |
Exercised RSUs |
| ( |
| — |
| — |
| — |
| — |
| — |
Forfeited RSUs |
| ( |
| — |
| ( |
| — |
| — |
| — |
RSUs granted at the end of the year |
| |
| — |
| |
| — |
| — |
| — |
Thereof exercisable |
| — |
| — |
| — |
| — |
| — |
| — |
The Awards in this table only include RSUs
F-56
The fair values of the grant of SPAs and RSAs were estimated on the date of grant using a Monte-Carlo-Simulation model with the following assumptions:
SPP 2022 | RSP 2020 | SPP 2022 | RSP 2020 | RSP 2020 | ||||||
granted | granted | granted | granted | granted | ||||||
| March |
| October |
| March |
| October |
| May | |
2024 | 2023 | 2023 | 2022 | 2022 | ||||||
Risk-free interest rate in % |
| | |
| |
| | | ||
Volatility of the Evotec SE share in % |
| | |
| |
| | | ||
Volatility of the TecDAX index in %. |
| | — |
| |
| — | — | ||
Fluctuation in % |
| |
| |
| | ||||
Exercise price in € |
| | |
| |
| | | ||
Share price on the day of issue in € |
| | |
| |
| | | ||
TecDAX index price on the day of issue in points |
| | — |
| |
| — | — | ||
Fair value in accordance with IFRS 2 on the date of issue per SPA of the Executive Board in € |
| | — |
| |
| — | | ||
Fair value in accordance with IFRS 2 on the date of issue per SPA of the executives in € |
| | |
| |
| | |
SPP 2017 | RSP 2020 | RSP 2020 | SPP 2017 | |||||
granted | granted | granted | granted | |||||
| January | October | May |
| February | |||
2022 | 2021 | 2021 | 2021 | |||||
Risk-free interest rate in % | ( | ( | ( | ( | ||||
Volatility of the Evotec SE share in % | | |
| | | |||
Volatility of the TecDAX index in %. | | — |
| — | | |||
Fluctuation in % | |
| ||||||
Exercise price in € |
| | |
| | | ||
Share price on the day of issue in € |
| | |
| | | ||
TecDAX index price on the day of issue in points |
| | — |
| — | | ||
Fair value in accordance with IFRS 2 on the date of issue per SPA of the Executive Board in € |
| | — |
| | | ||
Fair value in accordance with IFRS 2 on the date of issue per SPA of the executives in € |
| | |
| | |
For all SPAs, RSAs and RSUs, a total of €
The performance measurement period for all issues started on January 1 of the respective year. An expected dividend yield of
F-57
(13) Provisions
- Accounting principles -
Provisions are recognized if as a result of past events, the Group has:
| – | a present legal or constructive obligation, |
| – | the amount can be estimated reliably, and, |
| – | it is more likely than not that an outflow of resources will be required to settle the obligation. |
Provisions are measured at the present value of the expenditures expected to be required to settle the obligation using a pre-tax discount rate that reflects current market assessments of the time value of money.
A provision for onerous contracts is recognized when the expected benefits to be derived by the Group from such a contract are lower than the unavoidable expenses of meeting its obligations under the contract. The provision is measured at the present value of the lower of the expected expenses of terminating the contract and the expected net expense of continuing with the contract. Before a provision is established, the Group recognizes any impairment expense on the assets associated with that contract.
Reorganization provisions are recognized when the Group has a constructive obligation, which is when:
| – | there is a detailed formal plan that identifies the business or parts of the business concerned, the location and number of employees affected, the detailed estimate of the associated costs, and the timeline; and |
| – | the employees affected have been notified of the plan’s main features. |
- Provision -
The current provisions consist of the following:
December 31, | December 31, | |||
in k€ |
| 2024 |
| 2023 |
Other personnel expenses |
| |
| |
Pensions |
| |
| |
Other provisions |
| |
| |
Reorganization | | — | ||
Total current provisions |
| |
| |
The non-current provisions consist of the following:
December 31, | December 31, | |||
in k€ |
| 2024 |
| 2023 |
Pensions |
| |
| |
Other personnel expenses |
| |
| |
Other provisions |
| |
| |
Reorganization | | — | ||
Total non-current provisions |
| |
| |
F-58
The following table summarizes the development of total provisions recorded during 2024:
| Foreign | Remeasurement | ||||||||||||||
Jan 1, |
|
| Business | currency |
| through |
|
|
| Dec 31, | ||||||
2024 | Additions | combination |
| exchange | OCI | Consumption | Release | 2024 | ||||||||
k€ | k€ | k€ | k€ | k€ | k€ | k€ | k€ | |||||||||
Other personnel expenses |
| |
| |
| ( |
| | — | |
| | | |||
Pensions |
| |
| |
| ( |
| | ( | |
| | | |||
Other provisions |
| |
| |
| ( | |
| — |
| |
| |
| | |
Reorganization | — | | ( | | — | | | | ||||||||
Total |
| |
| |
| ( | |
| ( |
| | |
| |
The following table summarizes the development of total provisions recorded during 2023:
Foreign | Remeasurement | |||||||||||||||
| January 1, |
|
| Business |
| currency | through |
|
|
| Dec 31, | |||||
2023 | Additions | combination | exchange |
| OCI | Consumption | Release | 2023 | ||||||||
k€ | k€ | k€ | k€ | k€ | k€ | k€ | k€ | |||||||||
Other personnel expenses |
| |
| |
| — |
| | — |
| |
| |
| | |
Pensions |
| |
| |
| — |
| | — |
| |
| |
| | |
Other provisions |
| |
| |
| — |
| ( | — |
| |
| |
| | |
Reorganization | — | — | — | — | — | — | — | — | ||||||||
Total |
| |
| |
| — |
| ( | — |
| | |
| |
The provision for personnel expenses mainly consists of bonus accruals (December 31, 2024: €
The other provisions mainly consist of accrued audit fees (December 31, 2024: €
-Reorganization-
On April 24, 2024 as part of the publication of the 2023 Annual Results, the Group announced that it was currently assessing its current footprint and activities. As of December 31, 2024, the Group has recognized a provision of €
On November 2, 2024, the Group signed a SPA with Monacum partners to dispose of the Operation of Evotec DS in Halle (Germany). The Agreement closed on December 2, 2024.
As part of this Agreement, the Group sold the operations for €
F-59
(14) Financial Risk Management
- Liquidity Risk-
Revenue fluctuations, external events and changes in the business environment might negatively impact the Group’s short- to mid-term profitability and cash reserves. To actively address any related risk, the Group’s management has defined minimum liquidity levels and prepared a scenario planning to safeguard its cash position. The Group believes that existing liquidity reserves are sufficient to cope with the cumulative impact of all identified risks. The Group currently has sufficient liquidity reserves, due to a public placement in the United States in 2021 and securing additional external debt financing in 2023, most significantly a EUR
The option of increasing capital is always considered. This additional financing might be required if new business opportunities arise. The Group does not intend to engage in projects unless adequate funding is allocated or secured. Given the current business environment with economic and political uncertainties, the Group assesses the associated liquidity risks still to be low (previous year: low).
The general risk of losing a significant amount of cash in cash investments is continuously mitigated by spreading the investments across several different banks in high-credit quality instruments in full compliance with the Group’s approved investment policy. The Group monitors its banks and investments on an ongoing basis. Therefore, the Group assesses the current default risks to be low, remaining unchanged in comparison to the previous year.
Currency exchange movements also impact the Group’s reported liquidity primarily through the translation of liquid assets held in U.S. Dollars or Pound Sterling into Euros. A portion of the funds is held in currencies other than Euro to meet local operating needs. Political and economic uncertainties remain at a higher level causing volatility in the market.
F-60
The contractual maturities of the financial liabilities, including the estimated interest payments as of December 31, 2024 and 2023 are shown in the following tables:
December 31, 2024 | ||||||||||
| Carrying |
| Contractual |
| Due in |
| Due in |
| Due in more | |
amount | Cash flow | 1 year | 2 - 5 years | than 5 years | ||||||
k€ | k€ | k€ | k€ | k€ | ||||||
Non-derivative financial liabilities |
|
|
|
|
|
|
|
|
|
|
Loans |
| ( |
| ( |
| ( |
| ( |
| ( |
Lease obligations |
| ( |
| ( |
| ( |
| ( |
| ( |
Contingent consideration |
| — |
| — |
| — |
| — |
| — |
Trade accounts payable |
| ( |
| ( |
| ( |
| — | — | |
Other financial liabilities |
| ( | ( | ( | ( | — | ||||
Total non-derivative financial liabilities |
| ( | ( | ( | ( | ( | ||||
Derivative financial liabilities |
|
|
|
| ||||||
Foreign currency forwards |
| ( |
| ( |
| — |
| — | — | |
Total derivative financial liabilities |
| ( |
| ( |
| — |
| — |
| — |
| December 31, 2023 | |||||||||
Carrying | Contractual | Due in | Due in | Due in more | ||||||
| amount |
| Cash flow |
| 1 year |
| 2 - 5 years |
| than 5 years | |
k€ | k€ | k€ | k€ | k€ | ||||||
Non-derivative financial liabilities |
|
|
|
|
|
|
|
|
|
|
Loans |
| ( |
| ( |
| ( |
| ( |
| ( |
Lease obligations | ( | ( | ( | ( | ( | |||||
Contingent consideration |
| ( |
| ( |
| ( |
| — |
| — |
Trade accounts payable |
| ( |
| ( |
| ( |
| — |
| — |
Other financial liabilities | ( | ( | ( | ( | — | |||||
Total non-derivative financial liabilities |
| ( |
| ( |
| ( |
| ( |
| ( |
Derivative financial liabilities |
| |||||||||
Interest rate swaps/Foreign currency forwards |
| ( |
| ( |
| ( |
| ( |
| — |
Total derivative financial liabilities |
| ( |
| ( |
| ( |
| ( |
| — |
- Currency Risk-
The Group is exposed to foreign exchange risk as the Group entities enter into revenues, purchases, and other transactions in a currency other than the functional currency of the respective Group entity. The functional currencies of the Group entities are mainly Euro, US Dollar and British Pound. In the course of their ordinary business activities, the Group companies are exposed in particular to exchange rate fluctuations between US Dollar, British Pound and Euro. The amount of exchange differences recognized in the consolidated income statement except for those arising on financial instruments measured at fair value through profit or loss in accordance with IFRS 9 is a net gain of €
The table below shows the average exchange rates as well as the exchange rates as of December 31, 2024 and December 31, 2023, in each case against the Euro:
Annual average exchange rate |
| Closing rate Dec 31 | ||||||
2024 |
| 2023 | Dec. 31 | |||||
| Jan 1 - Dec 31 |
| Jan 1 - Dec 31 |
| 2024 |
| 2023 | |
€ | € | € | € | |||||
USD |
| |
| |
| |
| |
GBP |
| |
| |
| |
| |
F-61
A strengthening (weakening) of the Euro, the US Dollar and the British Pound among themselves and against other currencies, as shown below as at December 31, would lead to an increase (reduction) in equity and earnings with the amounts mentioned below. This analysis relates to financial instruments held for sale on condition that all other variables remain constant and ignore the impact of purchases and sales.
2024 | ||||||||||||
USD | GBP | EUR | ||||||||||
k€ |
| + |
| ( |
| + |
| ( |
| + |
| ( |
Share | | ( | | ( | | ( | ||||||
Result | | ( | | ( | | ( | ||||||
2023 | ||||||||||||
USD | GBP | EUR | ||||||||||
k€ |
| + |
| ( |
| + |
| ( |
| + |
| ( |
Share | | ( | | ( | | ( | ||||||
Result | | ( | | ( | | ( | ||||||
2022 | ||||||||||||
USD | GBP | EUR | ||||||||||
k€ |
| + |
| ( |
| + |
| ( |
| + |
| ( |
Share | | ( | | ( | | ( | ||||||
Result | | ( | | ( | | ( | ||||||
The Group manages foreign exchange exposure by incurring certain expenses in the currency of the local operating business and through selected hedging transactions such as foreign currency forward contracts. The hedging instruments used do not expose the Group to any significant additional risk. The objective of these transactions is to reduce the exposure of exchange rate fluctuations of the Group’s foreign currency denominated cash flows. The Group does not enter into derivative transactions for trading or speculative purposes. Foreign currency contracts are accounted for at fair value. Foreign currency derivative accounting gains and losses are included in non-operating income and expense amounted to a net loss of € (
Derived regularly from the summarized quantitative data about the Group’s currency risks, based on the report to the Management Board, the expected future USD cash flows which should be hedged with USD/GBP forward contracts and USD/EUR forward contracts are determined. As of December 31, 2024, cash flows of USD
-Interest Rate Risk-
The Group is exposed to interest rate risk through variable interest-bearing loans as well as current investments in Germany, but also at our foreign entities. The fair value of debt varies from the carrying amount if there is a difference between the underlying interest rate to the market interest rate.
These interest rate risks are considered immaterial.
F-62
-Credit Risk-
Credit risk is the risk of financial loss to the Group if a customer fails or partly fails to meet any of its contractual obligations and arises primarily from the receivables from customers, contract assets and investment securities. The maximum exposure to credit risk for trade receivables at the reporting date by geographic region is as follows:
| December 31, 2024 |
| December 31, 2023 | |
k€ | k€ | |||
USA |
| | | |
Europe |
| | | |
Rest of the world |
| | | |
| | |
The maximum credit risk of the contract assets corresponds to the carrying amounts and amounted to €
The Group has exposure to credit risk primarily with respect to its third-party receivables. The Group continuously assesses the solvency of its customers and maintains an appropriate specific allowance for bad debts, which is derived from the expected collectability of all receivables from third parties. The Group’s receivables from third parties are unsecured and not secured by any liens from customers. On December 31, 2024,
-Capital management risk-
The Group actively manages its funds to primarily ensure liquidity and principal preservation while seeking to maximize returns. The Group’s cash and short-term investments are held with several different banks. Financial investments are made in liquid, highly diversified investment instruments having at minimum a Standard & Poor’s rating (or equivalent) of at least BBB-.
The following table shows the total assets, equity as well as equity ratio and net cash (cash and cash equivalents minus current and non-current loan liabilities and current and non-current finance lease obligations):
| December 31, 2024 |
| December 31, 2023 |
| |
k€ | k€ |
| |||
Balance sheet total |
| | | ||
Equity attributable to Shareholders of Evotec SE |
| | | ||
Equity ratio in (%) |
| | % | | % |
Net cash |
| ( | ( |
The Group remains well financed with an equity ratio relating to equity attributable to the Group’s shareholders of
No minimum capital requirements are stipulated in Evotec’s statutes. The Company has obligations to issue shares out of the conditional capital relating to the exercise of stock options based on miscellaneous stock option plans as well as SPA on the basis of Share Performance Plans (see Note (12)).
F-63
(15) Fair Value of financial assets and liabilities
-Accounting Principles-
For financial reporting purposes, financial instruments are categorized into Level 1, 2 or 3, based on the degree to which the inputs to the fair value measurements are observable and the significance of the inputs to the fair value measurement in its entirety, which are as follows:
| - | Level 1 – inputs are quoted prices (unadjusted) for identical assets or liabilities in active markets that the company can access at the measurement date. |
| - | Level 2 – all significant inputs (other than quoted prices included within Level 1) are observable for the asset or liability, either directly (as prices) or indirectly (derived from prices). |
| - | Level 3 – one or more of the significant inputs are not based on observable market data, such as third-party pricing information without adjustments, for the asset or liability. |
Transfers between levels of the fair value hierarchy are recognized at the end of the reporting period during which the change has occurred.
Specific valuation techniques used to value financial instruments include:
Level 1
Instruments included in level 1 are comprised primarily of listed equity investments classified as financial assets carried at fair value through profit or loss or carried at fair value through other comprehensive income. The fair value of financial instruments traded in active markets is based on quoted market prices at the balance sheet date. A market is regarded as active if quoted prices are readily and regularly available from an exchange, dealer, broker, industry group, pricing service, or regulatory agency, and those prices represent actual and regularly occurring market transactions on an arm’s length basis.
Level 2
The fair value of financial instruments that are not traded in an active market (for example, over-the-counter derivatives or convertible bond instruments) is determined by using valuation techniques. These valuation techniques maximize the use of observable market data where it is available and rely as little as possible on entity-specific estimates. If all significant inputs required to fair value an instrument are based on observable market data, the instrument is included in level 2. The fair value of derivatives is calculated as the present value of the estimated future cash flows based on observable interest yield curves, basis spread and foreign exchange rates.
The fair value of debt is estimated on the basis of the quoted market prices for certain issuances, or on the basis of discounted cash flow analysis using market rates.
Level 3
If one or more of the significant inputs are not based on observable market data, such as third-party pricing information without adjustments, the instrument is included in level 3.
The fair value of contingent consideration is dependent on the terms of the respective acquisition agreement that may require the Group to pay additional consideration to former shareholders if specified future events occur or conditions are met.
The fair value measurement is based on management’s estimates and assumptions and hence classified as Level 3 in the fair value hierarchy.
F-64
-Fair Values-
The following table shows the fair value of the financial assets and liabilities measured at fair value and financial liabilities measured at amortized cost together with the corresponding carrying amounts from the statement of financial position as of December 31, 2024 and December 31, 2023 and their respective fair value level. For financial assets measured at amortized cost the carrying amount approximates the fair value.
December 31, 2024 | ||||||||||
Carrying | ||||||||||
in k€ |
| amount |
| Fair value |
| Level 1 |
| Level 2 |
| Level 3 |
Financial assets |
|
|
|
| ||||||
Equity instruments |
| | |
| — |
| |
| | |
Other financial assets |
| | |
| — |
| — |
| | |
Financial assets carried at FVtPL | | | — | | | |||||
Equity instruments | | | | — | — | |||||
Short - term investments | | | | — | — | |||||
Financial assets carried at FVtOCI | | | | — | — | |||||
Derivative financial instruments | — | — | — | — | — | |||||
Financial assets carried at fair value | | | | | | |||||
Financial liabilities | ||||||||||
Contingent consideration | — | — | — | — | — | |||||
Financial Liabilities carried at FVtPL | — | — | — | — | — | |||||
Derivative financial instruments | ( | ( | — | ( | — | |||||
Financial liabilities carried at fair value | ( | ( | — | ( | — | |||||
Trade account payables | ( | ( | — | — | — | |||||
Loans and borrowings | ( | ( | — | — | — | |||||
Other liabilities | ( | ( | — | — | — | |||||
Carried at (amortized) costs | ( | ( | — | — | — | |||||
Total financial liabilities |
| ( | ( |
| — |
| ( |
| — | |
F-65
December 31, 2023 | ||||||||||
Carrying | ||||||||||
in k€ |
| amount |
| Fair value |
| Level 1 |
| Level 2 |
| Level 3 |
Financial Asset |
|
|
|
| ||||||
Equity instruments |
| | |
| |
| |
| | |
Other financial assets | | | — | — | | |||||
Financial assets carried at FVtPL | | | | | | |||||
Equity instruments | | | | — | — | |||||
Short-term investments | | | | — | — | |||||
Financial assets carried at FVtOCI | | | | — | — | |||||
Derivative financial instruments | | | — | | — | |||||
Total financial assets carried at fair value | | | | | | |||||
Financial liabilities | ||||||||||
Contingent consideration | ( | ( | — | — | ( | |||||
Financial Liabilities carried at FVtPL | ( | ( | — | — | ( | |||||
Derivative financial instruments | ( | ( | ( | — | — | |||||
Financial liabilities carried at fair value | ( | ( | ( | — | ( | |||||
Trade account payables | ( | ( | — | — | — | |||||
Loans and borrowings | ( | ( | — | — | — | |||||
Other liabilities | ( | ( | — | — | — | |||||
Carried at (amortized) costs | ( | ( | — | — | — | |||||
Total financial liabilities |
| ( | ( |
| ( |
| — |
| ( | |
Short-term investments include investments which are measured at FVtOCI in the amount of €
F-66
Other Financials Assets carried at Fair Value through Profit & Loss consists of convertible loans granted to long-term investments in accordance with IFRS 9 in the amount of €
| Equity Instruments |
| ||
and other | Contingent | |||
in k€ | financial assets | consideration | ||
Balance as of January 1, 2024 |
| |
| ( |
Additions |
| |
| — |
Disposal | — | | ||
Transfer from Level 2 to Level 3 | | — | ||
Transfer from Level 3 to Level 2 | ( | — | ||
Fair Value Change | ( | — | ||
Conversion of loans to Investments in associates and Joint ventures | ( | — | ||
Balance as of December 31, 2024 | | — |
| Equity Instruments |
| ||
and other | Contingent | |||
in k€ | financial assets1 | consideration | ||
Balance as of January 1, 2023 | | ( | ||
Additions | | — | ||
Disposal | ( | — | ||
Transfer from Level 2 to Level 3 | — | — | ||
Transfer from Level 3 to Level 2 | ( | — | ||
Fair Value Change | ( | ( | ||
Conversion into Investments in associates and Joint ventures | — | — | ||
Balance as of December 31, 2023 | | ( |
The effects recognized in the income statement above from the adjustment of the fair values at level 3 were included in the consolidated income statement under “Other operating income” and “interest expense”. The two biggest investments included in Additions relate to Curie Bio Seed Fund I (2024: €
For the fair value of the level 3 hierarchy, possible alternative assumptions of significant unobservable inputs would have ceteris paribus the following effects as of December 31, 2024 and 2023:
2024 | 2023 | |||||||
Net result | Net result | |||||||
Increase | Decrease | Increase | Decrease | |||||
| k€ |
| k€ |
| k€ |
| k€ | |
Contingent consideration |
|
|
|
|
|
|
|
|
Discount rate (change of |
| — |
| — |
| ( |
| |
F-67
(16) Shareholder´s Equity
As of December 31, 2024,
The stock options exercised in 2024 have an average exercise price of €
The conditional capital of Evotec SE as of December 31, 2024 consists of
Pursuant to Section 5 (5) of the Company’s Articles of Association, the Management Board is authorized, with the approval of the Supervisory Board, to increase the Company’s share capital by up to €
As of December 31, 2024, Evotec holds
(17) Earnings per share
-Accounting Principles-
Basic EPS is calculated by dividing the Net income (loss) attributable to shareholders by the weighted average number of common shares outstanding during the period, adjusted for own shares held. Diluted EPS is determined by adjusting the Net income (loss) attributable to shareholders and the weighted average number of common shares outstanding during the period, adjusted for own shares held, for the effects of all dilutive potential common shares, which comprises forward purchase contracts, restricted shares, performance shares and share options granted to employees.
-Earnings per share-
The weighted average number of ordinary shares is calculated as follows:
Shares in thousands |
| 2024 |
| 2023 |
| 2022 |
Issued shares 1. Jan. | | |
| | ||
Treasury shares 1. Jan. |
| ( |
| ( | ( | |
Effect of weighted average stock options exercised |
| |
| | | |
Weighted Average Number of Shares Outstanding Dec 31. |
| |
| | |
F-68
(18) Commitments and contingencies
- Lease obligations-
The future minimum lease payments under non-cancellable lease agreements but not yet commenced, are as follows:
| Dec 31 | Dec 31 | ||
2024 | 2023 | |||
k€ | k€ | |||
Less than one year |
| | | |
Between one and five years |
| | | |
More than five years |
| | | |
Total |
| | |
In addition, the Group maintains leases which were not recognized in accordance with the exemptions in IFRS 16. These amounts are not material and therefore not presented here.
-Other Commitments and Contingencies-
The future minimum payments associated with miscellaneous commitments total approximately €
In addition, as of December 31, 2024, contingent liabilities in relation with milestone-based commitments in connection with the Group´s long-term investments amounted to €
The Group is not aware of any material actual or threatened litigation as of December 31, 2024.
(19) Related party transactions
The Group has not entered into any significant transactions with any key management personnel or member of the Supervisory Board. The remuneration paid to key management personnel is presented in Note 21 e). The remuneration paid to members of the Supervisory Board is shown in Note 21 e).
As part of the normal course of business, the Group may enter into transactions with associated companies. The terms and conditions of all transactions are made based on market terms and conditions and the arm’s length principle.
in k€ |
| 2024 |
| 2023 |
| 2022 |
Sales of goods and services |
| |
| |
| |
Receivables from related parties | | | |
(20) Auditor’s remuneration
BDO AG, Wirtschaftsprüfungsgesellschaft (BDO) has served as our independent registered public accounting firm for the year ended December 31, 2024 and December 31, 2023.
F-69
The following table sets out the aggregate fees for professional audit services and other services rendered exclusively by BDO and other firms in the BDO network in 2024, 2023 and 2022:
in k€ |
| 2024 |
| 2023 |
| 2022 |
Audit fees |
| | |
| | |
Audit-related fees |
| | |
| | |
Audit fees related to prior year audit |
| | |
| | |
All other fees |
| — | — |
| | |
Total |
| | |
| |
Audit fees aggregate fees charged by BDO network firms for auditing our consolidated financial statements and statutory and other regulatory filings or engagements of Evotec SE and its subsidiaries.
The Audit Committee has approved the audit fees and all the fees for other assurance services for the years 2024 and 2023. The Audit Committee monitors compliance with the German and U.S. rules on non-audit services provided by an independent registered public accounting firm. On a yearly basis, the Audit Committee pre-approves non-audit services performed by the independent registered public accounting firm up to a limit in line with EU regulation.
(21) Other disclosures
German law in accordance with the European Directives on Accounting and the Corporate Governance Codex requires the following additional disclosures.
a) Number of Employees
As of December 31, 2024, the Company employed
b) Corporate Governance Code
According to Sec 161 AktG, the Management Board and Supervisory Board issued statement of compliance with regard to the German Corporate Governance Code. This statement has been made accessible to the Company’s shareholders in the ‘Invest’ section on Evotec’s website (https://www.evotec.com/en/sustainability/governance).
F-70
(c) Consolidated subsidiaries and equity investees
Information below shows Evotec’s direct and indirect voting rights in their subsidiaries and other investments. Evotec’s direct and indirect voting rights in dormant companies are not included.
| 2024 | |
Company’s | ||
voting | ||
rights | ||
% | ||
Subsidiaries | ||
Aptuit Global LLC, Princeton, USA |
| |
Aptuit (Verona) SRL, Verona, Italy |
| |
Aptuit (Oxford) Ltd., Abingdon, UK |
| |
Aptuit (Potters Bar) Ltd., Abingdon, UK |
| |
Cyprotex Discovery Ltd., Manchester, UK |
| |
Cyprotex Ltd., Manchester, UK |
| |
Cyprotex US, LLC., Framingham, USA |
| |
Evotec (France) SAS, Toulouse, France |
| |
Evotec ID (Lyon) SAS, Marcy l’Étoile, France |
| |
Evotec (Hamburg) GmbH, Hamburg, Germany |
| |
Evotec GT GmbH, Orth an der Donau, Austria |
| |
Evotec (India) Private Limited, Thane, India* |
| |
Evotec International GmbH, Hamburg, Germany |
| |
Evotec (UK) Ltd., Abingdon, UK |
| |
Evotec (US), Inc., Princeton, USA |
| |
Just - Evotec Biologics, Inc., Seattle, USA |
| |
Just - Evotec Biologics EU SAS, Toulouse, France |
| |
Evotec (Modena) Srl, Medolla, Italy | | |
NephThera GmbH, Hamburg, Germany | | |
Evotec Asia Pte. Ltd., Shenton, Singapore | |
F-71
| 2024 | |
Company’s | ||
voting | ||
rights | ||
% | ||
Associates |
|
|
Breakpoint Therapeutics GmbH, Hamburg, Germany | | |
Centauri Therapeutics Ltd., Cheshire, UK |
| |
Dark Blue Therapeutics Ltd., Oxford, UK |
| |
EIR Biotherapies S.r.l., Mirandola (MO), Italy |
| |
Eternygen GmbH, Berlin, Germany* |
| |
Quantro Therapeutics GmbH, Vienna, Austria |
| |
TAG Therapeutics GmbH, Vienna, Austria |
| |
Topas Therapeutics GmbH, Hamburg, Germany |
| |
Other Investments |
|
|
Aeovian Pharmaceuticals Inc., San Francisco, USA |
| |
ArgoBio SAS, Paris, France | | |
Aurobac Therapeutics SAS, Lyon, France |
| |
Autobahn Labs, LLC, Palo Alto, CA USA |
| |
Blacksmith Medicines Inc., San Diego, CA USA |
| |
Cajal Neuroscience Inc., Seattle, USA |
| |
Carma Fund I, Munich, Germany |
| |
Carrick Therapeutics Inc., Boston, USA |
| |
Celmatix Inc., New York, USA |
| |
Curie Bio LLC, Boston, USA |
| |
Curie Bio Seed Fund I LP, Boston, USA |
| |
Extend S.r.l., Rome, Italy | | |
Fibrocor LLP, Toronto, Canada | | |
Fibrocor Therapeutics, Inc., Toronto, Canada | | |
IMIDomics Inc., San Rafael, CA, USA | | |
Immunitas Therapeutics Inc.*, Waltham, USA | | |
Leon Nanodrugs GmbH, Munich, Germany | | |
Mission BioCapital V LP, Cambridge, USA | | |
OxVax Ltd., Oxford, UK* | | |
Pluristyx Inc., Seattle, USA |
| |
Sernova Corp., Ontario, Canada | | |
Verto Therapeutics Inc., Boston, USA | | |
Tubulis GmbH, Munich, Germany | |
* | in liquidation |
The former Evotec (München) GmbH, Martinsried, Germany was merged with Evotec International GmbH, Hamburg, Germany. The former Evotec Drug Substance (Germany) GmbH, Halle, Germany was sold to an external investor. Further information regarding this transaction can be found in note 13.
Associates and joint ventures are accounted for using the equity method.
In Q1 2024, Evotec’s share in Autobahn Labs, LLC, Palo Alto, CA USA was diluted and the corresponding investment is no longer accounted for using the equity method and measured at fair value according to IFRS 9.
The Group’s investments in subsidiaries, associates and joint ventures are not hedged as these currency positions are considered to be long-term in nature.
F-72
(d) Management Board
Dr Christian Wojczewski, Chemist, Munich, Germany (Chief Executive Officer, since July 2024)
Dr Mario Polywka, Chemist, Oxfordshire, United Kingdom (Interim Chief Executive Officer, from January 2024 until June 2024)
Dr Werner Lanthaler, Business Executive, Hamburg, Germany (Chief Executive Officer, Chairperson of the Board until January, 2024),
Dr Cord Dohrmann, Biologist, Göttingen, Germany (Chief Scientific Officer),
Laetitia Rouxel, Business Executive, Clarens, Switzerland (Chief Financial Officer, until February 2025),
Paul Hitchin, Business Executive, Amsterdam, Netherlands (Chief Financial Officer, since March 2025),
Aurélie Dalbiez, Business Executive, Munich, Germany, (Chief People Officer, since June 2024),
Dr Craig Johnstone, Business Executive, Castillon-Savès, France (Chief Operating Officer, until December 2024) and
Dr Matthias Evers, Biochemist / Business Executive, Hamburg, Germany (Chief Business Officer, until September 2024).
The remuneration granted to the members of the Management Board for the financial years 2024 and 2023 are shown below:
in k€ |
| 2024 |
| 2023 |
Short-term employee benefits |
| |
| |
Termination benefits | |
| — | |
Stock-based compensation |
| ( |
| |
Total Remuneration |
| |
| |
F-73
The Members of the Management Board who hold additional memberships in supervisory boards and memberships in comparable governing bodies of enterprises are listed below.
Dr Mario Polywka | |
Non- Executive Director: | |
Blacksmith Medicines Inc, San Diego/USA (not listed) | |
C4X Discovery Holdings PLC, Manchester/UK (listed on the London Stock Exchange) (until January 2024) | |
Exscientia plc (now Recursion Inc.), Oxford/UK (listed on the NASDAQ) (until December 2024) | |
Orbit Discovery Limited, Oxford/UK (listed on the NASDAQ) | |
Dr Cord Dohrmann | |
Member of the Supervisory Board: | |
Eternygen GmbH, Berlin/DE* (not listed) | |
Breakpoint Therapeutics, Hamburg/DE* (not listed) | |
* Associated company of Evotec | |
Dr Matthias Evers | |
Non - Executive Member of the Board of Directors: | |
Angelini Ventures S.p.A., Rome/Italy (not listed) | |
IMIDomics Inc., San Rafel, CA/U.S.A. (not listed) (since September 2024) | |
Founder/CEO | |
Elbbridge GmbH, Hamburg/Germany (since September 2024) | |
(e) Supervisory Board
Prof. Dr Iris Löw-Friedrich, Member of the Management Board (Chief Medical Officer) of UCB S.A. (until July 2024) (listed on the Euronext Brussels/BE); Chairwoman of the Supervisory Board and Chairwomen of the Remuneration and Nomination Committee.
Roland Sackers, Chief Financial Officer and Managing Director of QIAGEN N.V. (listed on the Frankfurt Stock Exchange, Swiss Exchange, New York Stock Exchange and Luxembourg Stock Exchange); Vice Chairman of the Supervisory Board and Chairman of the Audit and Compliance Committee.
Camilla Macapili Languille, Deputy CEO, Mubadala Direct Investments (not listed); Member of the Supervisory Board.
Wesley Wheeler, CEO of LabConnect; Member of the Supervisory Board (since June 2024):
Dr Elaine Sullivan, Non-executive Director and Independent consultant; Member of the Supervisory Board (until June 2024).
Dr Constanze Ulmer-Eilfort Partner in the law firm Peters, Schönberger & Partner (not listed); Member of the Supervisory Board and Chairwoman of the ESG Committee.
Dr Duncan McHale, Co-founder and Director of Weatherden Ltd. (not listed), Member of the Supervisory Board (since June 2024)
F-74
The remuneration accrued of the Supervisory Board in the financial year was as follows:
in k€ |
| 2024 |
| 2023 |
Total renumeration of the supervisory board |
| |
| |
In the financial years 2024, the compensation per Supervisory Board member amounted to €
In the financial years 2024 and 2023, there was
The Company has a Directors and Officers liability insurance for the members of the Management Board, the Supervisory Board, its senior management and the directors of the subsidiary companies. An appropriate deductible has been agreed for the members of the Supervisory Board.
The members of the Supervisory Board and their additional memberships in supervisory boards and members in comparable governing bodies of enterprises according to Sec 125 (1) sentence 5 AktG are listed in the following:
Prof. Dr. Iris Löw-Friedrich | |
Chair of the Company / Supervisory Board: | |
Celosia Therapeutics Pty Ltd., New South Wales/AU (not listed) | |
Member of the Supervisory Board: | |
Fresenius SE & Co. KGaA, Bad Homburg/DE (listed on the Frankfurt, Düsseldorf and Munich Stock Exchange) | |
Roland Sackers | |
Member of the Board of Directors: | |
Bio Deutschland e.V., Berlin/DE (not listed) | |
Dr. Elaine Sullivan | |
Member of the Supervisory Board/Observer: (since November 2023; application for election to the Board of Directors in 2024): | |
Zealand Pharma A/S, Søborg/DK (listed on the NASDAQ Copenhagen) (since December 2023) | |
Non-executive Director: | |
Active Biotech AB, Lund/SE (listed on the NASDAQ OMX Nordic Exchange Stockholm) | |
(until May 2023) | |
Nykode Therapeutics ASA, Oslo/NO (listed on the Oslo Stock Exchange) | |
IP Group plc, London/UK (listed on the London Stock Exchange) | |
hVIVO plc (formerly Open Orphan plc), London/UK (listed on the London AIM and Euronext Growth Stock Exchange) (until May 2023) | |
Dr. Constanze Ulmer-Eilfort | |
Member of the Supervisory Board: | |
Affimed NV, Mannheim/Germany (listed on the NASDAQ New York) | |
Member of the Advisory Board: | |
Proxygen GmbH, Vienna/AT (not listed) | |
Dr Duncan McHale | |
F-75
Wesley Wheeler | |
Director of the Board: | |
Envirotainer A/S, Stockholm/SE (not listed) | |
Argenta Holdco Limited, London/UK (not listed) | |
Non-executive Director: | |
Mallinckrodt Pharmaceuticals, Dublin/IRL (since April 2024) (not listed; formerly listed on the NASDAQ) | |
Camilla Macapili Languille | |
Member of the Board of the Directors: | |
Globalfoundries Inc., New York/USA (listed on NASDAQ New York) | |
PCI Pharma Services, Philadelphia/USA (not listed) | |
(22) Subsequent events
On February 26, 2025, the company publicly announced that Laetitia Rouxel stepped down as Chief Financial Officer effective February 28, 2025. The Supervisory Board of Evotec SE appointed Paul Hitchin as new Chief Financial Officer and member of the Management Board with effect from March 1, 2025.
On March 3, 2025, Evotec SE drew €
Hamburg, April 14, 2025
Dr Christian Wojczewski |
| Aurélie Dalbiez |
| Dr Cord Dohrmann |
Paul Hitchin |
F-76