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Payment of Filing Fee (Check the appropriate box):
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x
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No fee required.
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o
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Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.
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(1
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Title of each class of securities to which transaction applies:
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(2
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Aggregate number of securities to which transaction applies:
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(3
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Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee is calculated and state how it was determined):
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(4
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Proposed maximum aggregate value of transaction:
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(5
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Total fee paid:
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o
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Fee paid previously with preliminary materials.
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o
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Check box if any part of the fee is offset as provided by the Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.
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(1
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Amount previously paid:
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(2
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Form, Schedule or Registration Statement No.:
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(3
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Filing Party:
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(4
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Date Filed:
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Sincerely yours,
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/S/ CRAIG J. TUTTLE
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Craig J. Tuttle
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President and Chief Executive Officer
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(1
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To elect one Class I director for a three-year term ending in 2016;
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(2
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To conduct an advisory vote to approve executive compensation; and
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(3
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To transact such other business as may properly come before the Annual Meeting or any adjournment or postponement thereof.
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By Order of the Board of Directors
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/S/ MARK P. COLONNESE
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Mark P. Colonnese,
Executive Vice President and
Chief Financial Officer
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Name and Address of Beneficial Owner
(1)
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Number of Shares Beneficially Owned
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Percent of Class
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Directors and Executive Officers
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Craig J. Tuttle, President and Chief Executive Officer, Director
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933,333
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(2)
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1.0%
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Mark P. Colonnese, Executive Vice President and Chief Financial Officer
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—
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*
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Brett L. Frevert, Former Chief Financial Officer
(3)
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—
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*
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Chad M. Richards, Chief Commercial Officer
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425,167
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(4)
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*
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Doit L. Koppler II, Director
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135,254
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(5)
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*
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Rodney S. Markin, M.D., Ph.D., Director
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75,000
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(6)
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*
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Robert M. Patzig, Director
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119,467
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(7)
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*
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Antonius P. Schuh, Ph.D., Director
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65,000
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(8)
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*
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All directors and executive officers as a group (7 persons)
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1,753,221
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(9)
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2.0%
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Other Stockholders
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Randal J. Kirk
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29,499,241
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(10)
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30.1%
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LeRoy C. Kopp
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13,559,863
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(11)
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15.4%
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Kevin Douglas
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8,514,812
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(12)
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9.4%
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AMH Equity, LLC and Leviticus Partners, L.P.
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5,248,181
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(13)
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5.9%
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Fidelity Select Biotechnology Portfolio
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5,087,982
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(14)
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5.7%
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Name and Address of Beneficial Owner
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Number of Shares Beneficially Owned
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Percent of Class
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Randal J. Kirk
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3,879,307
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(1)
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100
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%
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Name
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Age
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Principal Occupation
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Director Since
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Term to Expire
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CLASS I DIRECTOR NOMINEES
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Robert M. Patzig, Preferred Stock Director
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44
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Senior Managing Director and Chief Investment Officer, Third Security, LLC
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2010
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2013
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Craig J. Tuttle, Common Stock Director
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60
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President and Chief Executive Officer of Transgenomic, Inc.
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2007
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2013
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CLASS II DIRECTORS CONTINUING IN OFFICE
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Doit L. Koppler II, Preferred Stock Director
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49
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Managing Director and Treasurer, Third Security, LLC
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2010
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2014
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Antonius P. Schuh, Ph.D., Common Stock Director
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49
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Chief Executive Officer of Trovagene, Inc.
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2009
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2014
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CLASS III DIRECTOR CONTINUING IN OFFICE
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Rodney S. Markin, M.D., Ph.D., Common Stock Director
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56
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Chairman of the Board, Transgenomic, Inc., Chief Technology Officer, University of Nebraska Medical Center
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2007
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2015
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2012
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2011
|
||||
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Audit fees
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$
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275,305
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$
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321,005
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Audit-related fees
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31,250
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25,999
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Tax fees
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28,035
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30,190
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||
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All other fees
|
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—
|
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—
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Total fees
|
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$
|
334,590
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$
|
377,194
|
|
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Name
|
|
Age
|
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Title(s)
|
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Craig J. Tuttle
|
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60
|
|
President and Chief Executive Officer
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Mark P. Colonnese
|
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57
|
|
Executive Vice President and Chief Financial Officer
|
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Chad M. Richards
|
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43
|
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Chief Commercial Officer
|
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•
|
align the interests of our executives and stockholders by motivating executives to increase stockholder value and rewarding executives when stockholder value increases;
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•
|
motivate our executives to manage our business to meet our short and long-term objectives, and reward them for meeting these objectives.
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•
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Review, modify and approve individual and corporate performance goals and objectives relevant to Chief Executive Officer and other executive officers' compensation, evaluate performance in light of these goals and objectives, and determine and approve the compensation level for the Chief Executive Officer and other executive officers based on this evaluation.
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•
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Evaluate and approve incentive compensation plans and equity-based plans.
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•
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Adoption of stock option and other long-term incentive plans and approval of individual grants and awards.
|
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•
|
Adoption of equity compensation arrangements and policies with respect to the timing and pricing of equity awards for newly hired employees, promotions and annual grants for executives and non-executive employees and directors.
|
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•
|
Review compensation practices and trends to assess the proprietary, adequacy and the competitiveness of our executive compensation programs among comparable companies in our industry.
|
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•
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Adoption of benefit plans, including profit sharing and supplemental retirement plans.
|
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•
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Adoption of executive annual incentive plans, benefit plans, including profit sharing and supplemental retirement plans, and executive perquisite programs.
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•
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Annual evaluation and appraisal of President and Chief Executive Officer performance.
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•
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Approval of all employment agreements, severance agreements, change-of-control protections and any other compensatory arrangements for the President, Chief Executive Officer and other executive officers.
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•
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Annual review of non-employee director compensation programs and recommendation of changes to the Board when appropriate.
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•
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Review and establish appropriate insurance coverage for our directors and executive officers.
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•
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the ability of the executive to drive results for our Company;
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•
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the executive's understanding of our business and his/her organizational savvy;
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•
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the ability of the executive to make complex decisions and his/her strategic abilities;
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•
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the executive's ability to manage work process;
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•
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the communication skills of the executive; and
|
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•
|
the executive's ability to manage diversity and ethics.
|
|
Element of Compensation
|
Purpose
|
Pay-for-Performance Considerations
|
|
Cash and Short-Term Variable Compensation:
|
||
|
Base Compensation
|
Provides competitive, fixed compensation to attract and retain exceptional executive talent.
|
Adjustments to base salary consider the individual's overall performance, contribution to the business and internal and external comparisons.
|
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Cash Bonus
|
Encourages and rewards achievement of strong financial, operational and strategic performance.
|
The amount of any discretionary bonus received by an executive officer, if any, depends on the degree we achieve strong annual financial, operational or strategic performance and the extent to which the executive officer contributes to the achievement.
|
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Long-Term Compensation:
|
||
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Stock Options
|
Encourages executive officers to focus on our long-term performance, links an executive officer's incentives to our stockholders' interests in increasing our stockholder value, encourages significant ownership of our common stock and promotes long-term retention of our executive officers.
|
The potential appreciation in our stock price above the exercise price for stock options motivates our executives to build stockholder value as the executive officer only realizes value from the stock option if the stock price appreciates.
|
|
Other Elements:
|
||
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Health, Retirement and Other Benefits
|
Provides broad-based market competitive employee benefit programs such as participation in benefit plans generally available to our employees, including, employee stock purchase plan, 401(k) retirement plan, life, health and dental insurance and short-term and long-term disability plans.
|
Not applicable.
|
|
Target Attainment Percentage
|
Form of Payment
|
|
100%
|
Cash
|
|
Above 100%
|
50% Cash
50% Restricted Stock
|
|
MEMBERS OF THE COMPENSATION COMMITTEE:
|
|
|
|
Antonius P. Schuh, Ph.D.
|
|
Rodney S. Markin, MD, Ph.D.
|
|
Robert M. Patzig
|
|
Name and Principal Position
|
|
Year
|
|
Salary ($)
|
|
Bonus ($)
|
|
Option Awards
(1)
($)
|
|
All Other Compensation ($)
|
|
Total ($)
|
||||||||||
|
Craig J. Tuttle
(2)
|
|
2012
|
|
$
|
345,833
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
17,973
|
|
(3)
|
$
|
363,806
|
|
|
President and
|
|
2011
|
|
325,000
|
|
|
10,000
|
|
|
457,950
|
|
|
12,102
|
|
(4)
|
805,052
|
|
|||||
|
Chief Executive Officer
|
|
2010
|
|
325,000
|
|
|
—
|
|
|
—
|
|
|
18,377
|
|
(5)
|
343,377
|
|
|||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
Mark P. Colonnese
(6)
|
|
2012
|
|
96,106
|
|
|
—
|
|
|
198,250
|
|
|
2,056
|
|
(7)
|
296,412
|
|
|||||
|
Executive Vice President
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
and Chief Financial Officer
|
|
|
|
|
|
|
|
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|
||||||||||
|
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|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
Brett L. Frevert
(8)
|
|
2012
|
|
—
|
|
|
—
|
|
|
—
|
|
|
92,475
|
|
(8)
|
92,475
|
|
|||||
|
Former Chief Financial Officer
|
|
2011
|
|
—
|
|
|
5,000
|
|
|
228,975
|
|
|
242,250
|
|
(8)
|
476,225
|
|
|||||
|
|
|
2010
|
|
—
|
|
|
—
|
|
|
—
|
|
|
96,225
|
|
(8)
|
96,225
|
|
|||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
Chad M. Richards
(9)
|
|
2012
|
|
202,792
|
|
|
—
|
|
|
—
|
|
|
15,256
|
|
(10)
|
218,048
|
|
|||||
|
Chief Commercial Officer
|
|
2011
|
|
199,167
|
|
|
6,000
|
|
|
228,975
|
|
|
9,338
|
|
(11)
|
443,480
|
|
|||||
|
|
|
2010
|
|
188,708
|
|
|
—
|
|
|
—
|
|
|
13,476
|
|
(12)
|
202,184
|
|
|||||
|
Name
|
|
Grant Date
|
|
All Other Option Awards: Number of Securities Underlying Options (#)
|
|
Exercise or Price of Option Awards ($/sh)
(1)
|
|
Grant Date Fair Value of Option Awards ($)
(2)
|
|||||
|
Mark P. Colonnese
|
|
9/12/2012
|
|
250,000
|
|
|
$
|
0.98
|
|
|
$
|
198,250
|
|
|
|
|
|
Option Awards
|
|||||||||||
|
Name
|
Option Award / Grant Date
|
|
Number of Securities Underlying Unexercised Options (#) Exercisable
|
|
Number of Securities Underlying Unexercised Options (#) Unexercisable
|
|
Option Exercise Price ($)
|
|
Option Expiration Date
|
|||||
|
Craig J. Tuttle
|
9/1/2006
|
|
200,000
|
|
|
—
|
|
|
$
|
0.69
|
|
|
8/31/2016
|
|
|
Craig J. Tuttle
|
1/17/2007
|
|
200,000
|
|
|
—
|
|
|
0.75
|
|
|
1/16/2017
|
||
|
Craig J. Tuttle
|
7/12/2007
|
|
200,000
|
|
|
—
|
|
|
0.66
|
|
|
7/11/2017
|
||
|
Craig J. Tuttle
|
5/18/2011
|
|
166,667
|
|
(1)
|
333,333
|
|
(1)
|
1.19
|
|
|
5/17/2021
|
||
|
Mark P. Colonnese
|
9/12/2012
|
|
—
|
|
|
250,000
|
|
(2)
|
0.98
|
|
|
9/12/2022
|
||
|
Chad M. Richards
|
10/8/2007
|
|
200,000
|
|
|
—
|
|
|
0.69
|
|
|
10/7/2017
|
||
|
Chad M. Richards
|
5/18/2011
|
|
83,334
|
|
(1)
|
166,666
|
|
(1)
|
1.19
|
|
|
5/17/2021
|
||
|
Name
|
|
Benefit
|
|
Cause
|
|
Without Cause
(1)
|
|
Voluntary Termination
|
|
Change in Control
(1)
|
|
Death
(1)
|
|
Disability
(1)
|
|
Retirement
(1)
|
||||||||||||||
|
Craig. J. Tuttle
|
|
Cash
|
|
$
|
—
|
|
|
$
|
350,000
|
|
|
$
|
—
|
|
|
$
|
350,000
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
Stock options
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Benefits
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Total
|
|
$
|
—
|
|
|
$
|
350,000
|
|
|
$
|
—
|
|
|
$
|
350,000
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||
|
Mark P. Colonnese
|
|
Cash
|
|
$
|
—
|
|
|
$
|
206,250
|
|
|
$
|
—
|
|
|
$
|
206,250
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
Stock options
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Benefits
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Total
|
|
$
|
—
|
|
|
$
|
206,250
|
|
|
$
|
—
|
|
|
$
|
206,250
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||
|
Brett L. Frevert
|
|
Cash
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
Stock options
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Benefits
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Total
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||
|
Chad M. Richards
|
|
Cash
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
|
|
Stock options
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Benefits
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|
—
|
|
|||||||
|
|
|
Total
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
$
|
—
|
|
|
Name
|
|
Fees Earned or Paid in Cash ($)
|
|
Option Awards ($)
(1)
|
|
Total ($)
|
|
|
|
|
|
|
|
|
|
Doit Koppler, II
|
|
$22,000
|
|
$32,127
|
|
$54,127
|
|
Robert Patzig
|
|
24,625
|
|
32,127
|
|
56,752
|
|
Rodney Markin, M.D., Ph.D.
|
|
31,625
|
|
32,127
|
|
63,752
|
|
Antonius Schuh, Ph.D.
|
|
28,875
|
|
32,127
|
|
61,002
|
|
Name
|
|
Vested Stock Option Awards
|
|
Unvested Stock Option Awards
|
|
Aggregate Stock Option Awards
|
|||
|
Doit Koppler, II
|
|
65,000
|
|
|
—
|
|
|
65,000
|
|
|
Robert Patzig
|
|
65,000
|
|
|
—
|
|
|
65,000
|
|
|
Rodney Markin, M.D., Ph.D.
|
|
75,000
|
|
|
5,000
|
|
|
80,000
|
|
|
Antonius Schuh, Ph.D.
|
|
65,000
|
|
|
5,000
|
|
|
70,000
|
|
|
|
|
|
|
By Order of the Board of Directors
|
|
|
/S/ MARK P. COLONNESE
|
|
|
Mark P. Colonnese,
Executive Vice President and Chief Financial Officer
|
|
|
|
No information found
* THE VALUE IS THE MARKET VALUE AS OF THE LAST DAY OF THE QUARTER FOR WHICH THE 13F WAS FILED.
| FUND | NUMBER OF SHARES | VALUE ($) | PUT OR CALL |
|---|
| DIRECTORS | AGE | BIO | OTHER DIRECTOR MEMBERSHIPS |
|---|
No information found
No Customers Found
No Suppliers Found
Price
Yield
| Owner | Position | Direct Shares | Indirect Shares |
|---|