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| | | | | A-1 | | | |
| | | | | B-1 | | | |
| | | We provide internet proxy voting to allow you to vote your shares online, with procedures designed to ensure authenticity and correctness of your proxy vote instructions. Please be aware, however, that you must bear any costs associated with your internet access, such as usage charges from internet access providers and telephone companies. | | | | | |
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A:
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•
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For Proposal 1, which relates to the election of directors, the three (3) nominees receiving the highest number of “FOR” votes (from the holders of votes of shares present in person or represented by proxy at the 2018 Annual Meeting of Stockholders and entitled to vote on the election of directors) will be elected. Only votes FOR or WITHHELD will affect the outcome. Abstentions and broker non-votes will have no effect on the outcome of the vote as long as each nominee receives at least one FOR vote. You do not have the right to cumulate your votes. |
|
Name
|
| |
Age
|
| |
Position
|
| |
Director
Since |
|
|
Jeffrey J. Kraws
(1)(2)(3)
|
| |
54
|
| | Chairman | | |
2006
|
|
|
Scott L. Tarriff
(1)(2)(3)
|
| |
59
|
| | Director | | |
2012
|
|
|
Jeffrey Wolf, JD
(1)(2)(3)
|
| |
55
|
| | Director | | |
2006
|
|
|
Name
|
| |
Fees Earned or
Paid in Cash |
| |
Option
Awards (1)(3) |
| |
Other
Compensation |
| |
Total
|
| ||||||||||||
|
Jeffrey J. Kraws
(2)
|
| | | $ | 176,000 | | | | | $ | 65,000 | | | | | $ | — | | | | | $ | 241,000 | | |
|
Scott Tarriff
|
| | | $ | 48,000 | | | | | $ | 65,000 | | | | | $ | — | | | | | $ | 113,000 | | |
|
Jeffrey Wolf
|
| | | $ | 54,000 | | | | | $ | 65,000 | | | | | $ | — | | | | | $ | 119,000 | | |
|
Name
|
| |
Option
Awards (#) |
| |||
|
Jeffrey J. Kraws
|
| | | | 22,107 | | |
|
Scott Tarriff
|
| | | | 19,250 | | |
|
Jeffrey Wolf
|
| | | | 19,964 | | |
| | | |
December 31,
|
| |||||||||
| | | |
2017
|
| |
2016
|
| ||||||
|
Audit Fees and Expenses
(1)
|
| | | $ | 305,000 | | | | | $ | 334,000 | | |
| | | | | $ | 305,000 | | | | | $ | 334,000 | | |
| | |||||||||||||
| | | |
ESTIMATED NUMBER
OF SHARES OF COMMON STOCK BEFORE INCREASE (1) |
| |
ESTIMATED NUMBER
OF SHARES OF COMMON STOCK AFTER THE INCREASE |
| ||||||
|
Authorized
|
| | | | 10,000,000 | | | | | | 200,000,000 | | |
|
Outstanding
|
| | | | 3,799,136 | | | | | | 3,799,136 | | |
|
Issuable upon exercise of outstanding warrants and options
and conversion of preferred stock |
| | | | 1,908,660 | | | | | | 1,908,660 | | |
|
Reserved for issuance
(2)
|
| | | | 170,674 | | | | | | 170,674 | | |
|
Authorized but unissued
(3)
|
| | | | 4,121,530 | | | | | | 194,121,530 | | |
| | | |
2017
|
| |
2016
|
| |
2015
|
| |||||||||
|
Burn Rate
(1)
|
| | | | 2.54 % | | | | | | 4.10 % | | | | | | 4.69 % | | |
| Dilution (2) | | | | | 12.37 % | | | | | | 11.46 % | | | | | | 10.40 % | | |
| Overhang (3) | | | | | 8.56 % | | | | | | 8.79 % | | | | | | 8.82 % | | |
|
2010 Stock Incentive Plan
|
| ||||||
|
Name and position
|
| |
Number of shares
subject to grant |
| |||
|
Steven A. Shallcross, Interim Chief Executive Officer and Chief Financial Officer
|
| | | | 58,572 | | |
|
Joseph Sliman, Chief Medical Officer
|
| | | | 45,193 | | |
|
Jeffrey J. Kraws, Chairman of the Board of Directors
|
| | | | 21,393 | | |
|
Scott L. Tarriff, Director
|
| | | | 18,536 | | |
|
Jeffrey Wolf, Director
|
| | | | 18,536 | | |
|
All Current Executive Officers as a Group (two (2) persons)
|
| | | | 103,764 | | |
|
All Current Non-Executive Directors as a Group (three (3) persons)
|
| | | | 58,465 | | |
| | Acelrx Pharmaceuticals Inc. | | | Achaogen Inc. | | |
Achillion Pharmaceuticals
|
| | Ardelyx Inc. | |
| | Argos Therapeutics Inc. | | | Assembly Biosciences | | | Athersys Inc. | | | Cempra Inc. | |
| | Concert Pharmaceuticals Inc. | | | Cytrx Corp | | | Flexion Therapeutics Inc. | | | GTX Inc. | |
| |
Ironwood Pharmaceuticals, Inc.
|
| | Protein Therapeutics Inc. | | | Seres Therapeutics Inc. | | | Soligenix, Inc. | |
| |
Sucampo Pharmaceuticals, Inc.
|
| |
Synergy Pharmaceuticals,
Inc. |
| |
Tetraphase
Pharmaceuticals |
| |
Vitality
Biopharma Inc. |
|
|
Named Executive Officer
|
| |
Base Salary
|
| |||
|
Steven A. Shallcross, Interim Chief Executive Officer, Chief Financial Officer, Treasurer and Secretary
|
| | | $ | 381,150 (1) | | |
|
Joseph Sliman, Chief Medical Officer
|
| | | $ | 385,000 | | |
|
Name and Principal Position
|
| |
Year
|
| |
Salary
($) |
| |
Bonus
($) |
| |
Options
Awards ($) (1) |
| |
All Other
Compensation ($) (2) |
| |
Total
($) |
| ||||||||||||||||||
|
Steven Shallcross
(3)
Interim Chief Executive Officer and Chief Financial Officer |
| |
2017
|
| | | $ | 346,500 | | | | | $ | 200,000 (4) | | | | | $ | 177,746 | | | | | $ | 74,644 | | | | | $ | 798,890 | | | |||
| |
2016
|
| | | $ | 315,000 | | | | | $ | 236,250 | | | | | $ | 320,003 | | | | | $ | 49,929 | | | | | $ | 921,182 | | | |||||
| |
2015
|
| | | $ | 183,750 | | | | | $ | 137,813 | | | | | $ | 2,119,855 | | | | | $ | 11,657 | | | | | $ | 2,453,075 | | | |||||
|
Joseph Sliman
(5)
Chief Medical Officer |
| |
2017
|
| | | $ | 385,000 | | | | | $ | 216,563 (4) | | | | | $ | 236,305 | | | | | $ | 48,613 | | | | | $ | 886,481 | | | |||
| |
2016
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | |||||
| |
2015
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | |||||
|
Jeffrey Riley
(6)
Former President and Chief Executive Officer |
| | | | 2017 | | | | | $ | 508,333 | | | | | $ | 200,000 (4) | | | | | $ | — | | | | | $ | 677,891 | | | | | $ | 1,386,224 | | |
| | | | 2016 | | | | | $ | 550,000 | | | | | $ | 412,500 | | | | | $ | 722,560 | | | | | $ | 66,703 | | | | | $ | 1,751,763 | | | ||
| | | | 2015 | | | | | $ | 396,875 | | | | | $ | 288,750 | | | | | $ | 1,767,490 | | | | | $ | 97,986 | | | | | $ | 2,551,101 | | | ||
| |
Median Employee total annual compensation
|
| | | $ | 175,000 | | |
| |
Mr. Riley (‘‘CEO’’) total annual compensation
|
| | | $ | 614,000 | | |
| |
Ratio of CEO to Median Employee Compensation
|
| | | | 3.51:1.0 | | |
|
Name
|
| |
Grant
Date (1) |
| |
Number of
Securities Underlying Unexercised Options Exercisable |
| |
Number of
Securities Underlying Unexercised Options Unexercisable |
| |
Option
Exercise Price ($) |
| |
Option
Expiration Date |
| |||||||||||||||
|
Steven Shallcross
|
| | | | 12/20/17 | | | | | | — | | | | | | 15,714 | | | | | $ | 18.20 | | | | | | 12/20/24 | | |
| | | | | | 11/30/16 | | | | | | 5,159 | | | | | | 9,127 | | | | | $ | 28.00 | | | | | | 11/30/23 | | |
| | | | | | 12/04/15 | | | | | | 1,905 | | | | | | 952 | | | | | $ | 96.60 | | | | | | 12/04/22 | | |
| | | | | | 06/01/15 | | | | | | 21,429 | | | | | | 4,286 | | | | | $ | 75.60 | | | | | | 06/01/25 | | |
|
Joseph Sliman
|
| | | | 12/20/17 | | | | | | — | | | | | | 11,714 | | | | | $ | 18.20 | | | | | | 12/20/24 | | |
| | | | | | 01/17/17 | | | | | | 1,649 | | | | | | 3,748 | | | | | $ | 29.05 | | | | | | 01/17/24 | | |
| | | | | | 11/30/16 | | | | | | 3,382 | | | | | | 5,984 | | | | | $ | 28.00 | | | | | | 11/30/23 | | |
| | | | | | 12/04/15 | | | | | | 5,238 | | | | | | 2,619 | | | | | $ | 96.60 | | | | | | 12/03/22 | | |
| | | | | | 12/31/14 | | | | | | 857 | | | | | | — | | | | | $ | 51.10 | | | | | | 12/31/24 | | |
| | | | | | 02/24/14 | | | | | | 10,000 | | | | | | — | | | | | $ | 95.55 | | | | | | 02/23/19 | | |
|
Jeffrey Riley
|
| | | | 11/30/16 | | | | | | 10,752 | | | | | | — | | | | | $ | 28.00 | | | | | | 12/04/18 | | |
| | | | | | 12/04/15 | | | | | | 9,524 | | | | | | — | | | | | $ | 96.90 | | | | | | 12/04/18 | | |
| | | | | | 01/08/15 | | | | | | 9,167 | | | | | | | | | | | $ | 53.90 | | | | | | 12/04/18 | | |
| | | | | | 04/17/14 | | | | | | 14,286 | | | | | | — | | | | | $ | 88.20 | | | | | | 12/04/18 | | |
| | | | | | 02/03/12 | | | | | | 21,429 | | | | | | — | | | | | $ | 80.50 | | | | | | 12/04/18 | | |
| | | | | | 11/17/11 | | | | | | 2,857 | | | | | | — | | | | | $ | 17.15 | | | | | | 11/17/18 | | |
| | | | | | 01/05/11 | | | | | | 714 | | | | | | — | | | | | $ | 52.50 | | | | | | 01/05/18 | | |
| | | | | | 12/01/10 | | | | | | 238 | | | | | | — | | | | | $ | 25.90 | | | | | | 12/04/18 | | |
| | | | | | 03/03/10 | | | | | | 714 | | | | | | — | | | | | $ | 30.45 | | | | | | 12/04/18 | | |
|
Name
|
| |
Grant
Date |
| |
All Other
Stock Awards: Number of Shares of Stock or Units (#) |
| |
All Other
Stock Awards: Number of Securities Underlying Options (1) |
| |
Exercise or
Base Price of Option Awards ($/Sh) |
| |
Grant Date
Fair Value of Stock and Option Awards (2) |
||||||||||||||
|
Steven Shallcross
|
| | | | 12/20/17 | | | | | | — | | | | | | 15,714 | | | | | $ | 18.20 | | | | | $ | 177,000 |
|
Joseph Sliman
|
| | | | 01/17/17 | | | | | | — | | | | | | 5,398 | | | | | $ | 29.05 | | | | | $ | 104,000 |
| | | | | | 12/20/17 | | | | | | — | | | | | | 11,714 | | | | | $ | 18.20 | | | | | $ | 132,000 |
|
Name
|
| |
Event
|
| |
Salary &
Other Continuing Payments ($) |
| |
Extension of
Post-Termination Exercise Period ($) (4) |
| |
Total
($) |
| |||||||||
|
Steven A. Shallcross
|
| |
Termination without Cause or
resignation for Good Reason |
| | | $ | 421,000 (1) | | | | | $ | — | | | | | $ | 421,000 | | |
| | | | Upon Death or Disability | | | | $ | — | | | | | $ | — | | | | | $ | — | | |
| | | |
Termination without Cause or
resignation for Good Reason following a Change of Control |
| | | $ | 1,264,000 (2) | | | | | $ | — | | | | | $ | 1,264,000 | | |
| Joseph Sliman | | |
Termination without Cause or
resignation for Good Reason |
| | | $ | 434,000 (1) | | | | | $ | — | | | | | $ | 434,000 | | |
| | | | Upon Death or Disability | | | | $ | — | | | | | $ | — | | | | | $ | — | | |
| | | |
Termination without Cause or
resignation for Good Reason following a Change of Control |
| | | $ | 1,153,000 (2) | | | | | $ | — | | | | | $ | 1,153,000 | | |
| | | | Change of Control | | | | $ | — | | | | | $ | — | | | | | $ | — | | |
| Jeffrey Riley | | |
Termination without Cause or
resignation for Good Reason |
| | | $ | 878,000 (3) | | | | | $ | 2,000 | | | | | $ | 880,000 | | |
| | | |
Shares Owned
(1)
|
| |||||||||
|
Name and Address of Beneficial Ownership
(2)
|
| |
Number of
Share Owned |
| |
Percentages
of Shares (3) |
| ||||||
|
Randal J. Kirk and affiliated entities
(4)
|
| | | | 378,236 | | | | | | 9.96 % | | |
| Intrexon (4) | | | | | 274,664 | | | | | | 7.22 % | | |
|
Jeffrey J. Kraws
(5)
|
| | | | 20,600 | | | | | | * | | |
|
Jeff Riley (Former Chief Executive Officer)
(6)
|
| | | | 69,263 | | | | | | 1.79 % | | |
|
Steven Shallcross
(7)
|
| | | | 41,071 | | | | | | * | | |
|
Joeseph Sliman
(8)
|
| | | | 29,929 | | | | | | * | | |
|
Scott L. Tarriff
(9)
|
| | | | 36,921 | | | | | | * | | |
|
Jeffrey Wolf
(10)
|
| | | | 11,206 | | | | | | * | | |
|
All officers and directors as a group (6 persons)
|
| | | | 208,990 | | | | | | 5.23 % | | |
|
Plan Category
|
| |
Number of Securities
to be Issued Upon Exercise of Outstanding Options |
| |
Weighted-Average
Exercise Price of Outstanding Options |
| |
Number of Securities
Remaining Available for Future Issuance Under Equity Compensation Plans |
| |||||||||
|
Equity compensation plans approved by stockholders:
|
| | | | | | | | | | | | | | | | | | |
|
2007 Stock Incentive Plan
|
| | | | 20,350 | | | | | $ | 59.15 | | | | | | — | | |
|
2010 Stock Incentive Plan
|
| | | | 327,322 | | | | | $ | 54.25 | | | | | | 170,674 | | |
|
Equity compensation plans not approved by stockholders
|
| | | | — | | | | | | N/A | | | | | | N/A | | |
|
Total
|
| | | | 347,672 | | | | | $ | 54.25 | | | | | | 170,674 | | |
| | |||||||||||||||||||
| | | |
FOR ALL NOMINEES
|
| |
WITHHOLD AUTHORITY
FOR ALL NOMINEES |
| |
WITHHELD FOR THE
FOLLOWING ONLY: (WRITE THE NAME(S) OF THE NOMINEE(S) IN THE SPACE BELOW) |
| ||||||
| | | | | | ☐ | | | | | | ☐ | | | | | |
| | | |
FOR
|
| |
AGAINST
|
| |
ABSTAIN
|
| |||||||||
| | | | | | ☐ | | | | | | ☐ | | | | | | ☐ | | |
| | | |
FOR
|
| |
AGAINST
|
| |
ABSTAIN
|
| |||||||||
| | | | | | ☐ | | | | | | ☐ | | | | | | ☐ | | |
| | | |
FOR
|
| |
AGAINST
|
| |
ABSTAIN
|
|
| | | |
☐
|
| |
☐
|
| |
☐
|
|
| |
|
|
| |
|
|
| |
Meeting Attendance
Mark the box to the right if you plan to attend the 2018 Annual Meeting of Stockholders. |
| |
☐ |
|
No information found
* THE VALUE IS THE MARKET VALUE AS OF THE LAST DAY OF THE QUARTER FOR WHICH THE 13F WAS FILED.
| FUND | NUMBER OF SHARES | VALUE ($) | PUT OR CALL |
|---|
| DIRECTORS | AGE | BIO | OTHER DIRECTOR MEMBERSHIPS |
|---|
No information found
No Customers Found
No Suppliers Found
Price
Yield
| Owner | Position | Direct Shares | Indirect Shares |
|---|