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[ ]
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Preliminary Proxy Statement
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[ ]
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Confidential, for Use of the SEC Only (as permitted by
Rule 14a-6(e)(2))
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[X]
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Definitive Proxy Statement
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[ ]
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Definitive Additional Materials
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[ ]
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Soliciting Material Pursuant to 14a-12
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1.
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Title of each class of securities to which transaction
applies:
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2.
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Aggregate number of securities to which transaction
applies:
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3.
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Per unit price or other underlying value of transaction computed
pursuant to Exchange Act Rule 0-11 (set forth the amount on
which the filing fee is calculated and state how it was
determined):
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4.
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Proposed maximum aggregate value of transaction:
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5.
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Total fee paid:
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1.
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Amount Previously Paid:
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2.
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Form, Schedule or Registration Statement No.:
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3.
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Filing Party:
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4.
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Date Filed:
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Sincerely,
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Jon S. Saxe
Chairman of the Board of Directors
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YOUR VOTES ARE IMPORTANT
A
ll stockholders are cordially
invited to virtually attend the Meeting. However, to ensure your
representation at the Meeting, you are urged to vote in advance of
the meeting, as promptly as possible, electronically via the
Internet or by telephone. You may also vote by postal mail in
advance of the Meeting. Submitting your votes in advance of the
Meeting assures that a quorum will be present at the Meeting. Any
stockholder attending the Meeting virtually may vote at the
Meeting, even if such stockholder has returned a proxy prior to the
Meeting.
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By Order of the Board of Directors,
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Jerrold D. Dotson
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Chief Financial Officer and Corporate Secretary
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Shares of common stock
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As of
January 4,
2021
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Outstanding
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138,543,190
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Issuable
upon conversion of outstanding shares of our preferred
stock:
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Series
A Preferred Stock
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750,000
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Series B 10% Convertible Preferred
Stock
(1)
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1,131,669
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Series
C Convertible Preferred Stock
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2,318,012
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Series
D Convertible Preferred Stock
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46,000,000
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Issuable
upon exercise of warrants outstanding
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24,435,334
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Issuable
upon exercise of options outstanding
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12,343,088
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Reserved
for future grants, awards and issuances under our 2019 Omnibus
Equity Incentive Plan
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4,390,162
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Reserved
for future purchases under our 2019 Employee Stock Purchase
Plan
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941,875
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Outstanding
or reserved on a fully diluted basis
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230,853,330
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(1)
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Does
not include shares of common stock issuable upon conversion of
outstanding Series B 10% Convertible Preferred Stock as payment of
accrued, but unpaid, dividends.
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Name
and address of beneficial owner
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Number
of shares beneficially owned
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Percent
of
shares beneficially
owned
(1)
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Executive officers and directors:
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Shawn K. Singh,
J.D.
(2)
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61,609
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*
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H. Ralph Snodgrass,
Ph.D.
(3)
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87,724
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*
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Mark A. Smith,
M.D., Ph.D.
(4)
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10,000
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*
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Jerrold D. Dotson
(5)
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10,000
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*
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Mark McPartland
(6)
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-
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*
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Jon S. Saxe, J.D.,
LL.M.
(7)
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53,251
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*
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Brian J. Underdown,
Ph.D.
(8)
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-
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*
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Jerry B. Gin,
Ph.D., MBA
(9)
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100,000
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*
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Ann M. Cunningham,
MBA
(10)
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-
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*
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All executive
officers and directors as a group (9 persons)
(11)
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322,584
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*
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5% Stockholders:
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Entities associated
with New Enterprise Associates
(12)
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9,360,000
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6.76
%
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Entities affiliated
with Venrock
(13)
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9,360,000
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6.76
%
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Acuta Capital
Partners, LLC
(14)
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7,500,000
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5.41
%
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Orbimed Advisors
LLC
(15)
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7,500,000
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5.41
%
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Name
and address of beneficial owner
(16)
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Number
of shares beneficially owned
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Percent
of
shares beneficially
owned
(17)
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5% Stockholders:
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Entities associated
with New Enterprise Associates
(12)
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301,852
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15.09
%
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Entities affiliated
with Venrock
(13)
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301,852
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15.09
%
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Acuta Capital
Partners, LLC
(14)
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240,741
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12.04
%
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Orbimed Advisors LLC
(15)
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240,741
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12.04
%
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Franklin Advisors, Inc.
(18)
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201,111
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10.06
%
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(1)
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Based
on 138,543,190 shares of common stock issued and outstanding as of
January 4, 2021.
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(2)
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Excludes
options to purchase 1,786,253 shares of common stock and warrants
to purchase 72,000 restricted shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Mr. Singh in connection with the
Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Mr. Singh
will beneficially own a total of 1,919,862 shares of common stock,
or approximately 1.37%.
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(3)
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Excludes
options to purchase 1,095,625 shares of common stock and warrants
to purchase 50,000 restricted shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Dr. Snodgrass in connection with
the Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Dr.
Snodgrass will beneficially own a total of 1,233,349 shares of
common stock.
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(4)
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Excludes
options to purchase 1,094,375 shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Dr. Smith in connection with the
Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Dr. Smith
will beneficially own a total of 1,104,375 shares of common
stock.
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(5)
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Excludes
options to purchase 978,502 shares of common stock, including
options to purchase 626 shares of common stock held by Mr.
Dotson’s wife, and warrants to purchase 10,000 restricted
shares of common stock that would otherwise be exercisable within
60 days of January 4, 2021, but for a lock-up agreement executed by
Mr. Dotson in connection with the Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Mr. Dotson
will beneficially own a total of 998,502 shares of common
stock.
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(6)
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Excludes
options to purchase 924,375 shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Mr. McPartland in connection with
the Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Mr.
McPartland will beneficially own a total of 924,375, shares of
common stock.
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(7)
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Excludes
options to purchase 468,751 shares of common stock and warrants to
purchase 7,500 restricted shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Mr. Saxe in connection with the
Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Mr. Saxe
will beneficially own a total of 529,502 shares of common
stock.
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(8)
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Excludes
options to purchase 468,751 shares of common stock and warrants to
purchase 7,500 restricted shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Dr. Underdown in connection with
the Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Dr.
Underdown will beneficially own a total of 476,251 shares of common
stock.
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(9)
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Includes
50,000 restricted shares of common stock held by Dr. Gin’s
wife. Excludes options to purchase 491,251 shares of common stock
and warrants to purchase 100,000 registered shares of common stock,
including currently exercisable warrants to purchase 50,000
registered shares held by Dr. Gin’s wife, that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Dr. Gin in connection with the
Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Dr. Gin
will beneficially own a total of 691,251 shares of common
stock.
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(10)
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Excludes
options to purchase 181,251 shares of common stock that would
otherwise be exercisable within 60 days of January 4, 2021, but for
a lock-up agreement executed by Ms. Cunningham in connection with
the Public Offering.
Following
the expiration of the aforementioned lock-up agreement, Ms.
Cunningham will beneficially own a total of 181,251 shares of
common stock.
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(11)
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Includes
50,000 restricted shares of common stock held by Dr. Gin's wife.
Excludes options to purchase 7,489,134 shares of common stock and
warrants to purchase 100,000 registered shares and 147,000
restricted shares of common stock that would otherwise be
exercisable within 60 days of January 4, 2021, but for lock-up
agreements executed by each executive officer and director in
connection with the Public Offering.
Following
the expiration of the aforementioned lock-up agreements, the
Company’s executive officers and directors will beneficially
own an aggregate of 7,877,467 shares of common stock, or
approximately 5.39%.
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(12)
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Based
upon Schedule 13D filed by Growth Opportunities 17, LLC on January
4, 2021, and on the Company’s records through January 4,
2021.
The shares held by
Growth
Opportunities 17, LLC (
GEO
)
are indirectly held by
N
ew
Enterprise Associates 17, L.P. (
NEA
17
),
which is the sole member of GEO; NEA Partners 17, L.P.
(
NEA
Partners 17
), which is the sole
general partner of NEA 17; and NEA 17 GP, LLC (
NEA
17 LLC
and, together with NEA
Partners 17, the
Control
Entities
), which is the sole
general partner of NEA Partners 17.
The
Managing Members of NEA 17 LLC are
Forest Baskett, Ali
Behbahani, Carmen Chang, Anthony A. Florence, Jr., Liza Landsman,
Mohamad H. Makhzoumi, Joshua Makower, Edward T. Mathers, Scott D.
Sandell, Peter W. Sonsini, Paul Walker and Rick Yang (together,
the
Managers
).
GEO is the record owner of the shares identified herein (the
GEO
Shares
). As the sole member
of GEO, NEA 17 may be deemed to own beneficially the GEO Shares. As
the general partner of NEA 17, NEA Partners 17 may be deemed to own
beneficially the GEO Shares. As the sole general partner of NEA
Partners 17, NEA 17 LLC may be deemed to own beneficially the GEO
Shares. As members of NEA 17 LLC, each of the Managers may be
deemed to own beneficially the GEO Shares. Each of the
aforementioned reporting persons disclaims beneficial ownership of
the GEO Shares other than those shares which such person owns of
record.
The principal business address for GEO 10 is
1954 Greenspring Drive,
Suite 600, Timonium, MD 21093
.
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(13)
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Based
upon the Company’s records through January 4, 2021. Entities
associated with Venrock that hold the securities listed herein
include Venrock Healthcare Capital Partners II, L.P.; VHCP
Co-Investment Holdings II, LLC and Venrock Healthcare Capital
Partners EG, L.P. VHCP Management II, LLC (
VHCPM
) is the sole general partner of
Venrock Healthcare Capital Partners II, L.P. and the sole manager
of VHCP Co Investment Holdings II, LLC. VHCP Management EG, LLC
(
VHCPEG
) is the sole
general partner of Venrock Healthcare Capital Partners EG, L.P. Dr.
Bong Koh and Nimish Shah are the voting members of VHCPM and
VHCPEG.
The
address of each of the entities and individuals identified in this
footnote is c/o
Venrock
, 7 Bryant Park,
23rd
Floor, New York, NY
10018.
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(14)
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Based
upon the Company’s records through January 4, 2021. Anupam
Dalal is the Chief Investment Officer and Manfred Yu is the Manager
of Acuta Capital Partners, LLC (
Acuta
). Both Mr. Dalal and
Mr. Yu have voting and investment authority over all of the
shares held by each of Acuta, and disclaim beneficial ownership
except to
the extent of their indirect pecuniary interests therein
.
The business address for Acuta is 1301 Shoreway Road, Suite 350,
Belmont, California 94002.
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(15)
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Based
upon the Company’s records through January 4, 2021.
OrbiMed
Advisors LLC (
Orbimed
)
exercises voting and investment power through a management
committee comprised of Carl L. Gordon, Sven H. Borho, and Jonathan
T. Silverstein,
each of whom disclaim beneficial ownership
except to
the extent of their indirect pecuniary interests therein
.
The
business address for OrbiMed is c/o OrbiMed Advisors LLC, 601
Lexington Avenue, 54th Floor, New York, NY
10022.
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(16)
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Ownership
of our directors and named executive officers are not included, as
no directors or named executive officers hold shares of Series D
Preferred.
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(17)
|
Based
on 2,000,000 shares of Series D Preferred issued and outstanding as
of January 4, 2021.
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(18)
|
Based
upon the Company’s records through January 4, 2021. These
shares are beneficially owned by one or more open - or closed - end
investment companies or other managed accounts that are investment
management clients of investment managers that are direct and
indirect subsidiaries (
Investment
Management Subsidiaries
) of Franklin Resources, Inc.
(
FRI
). Charles B. Johnson
and Rupert H. Johnson, Jr. (
Principal Shareholders
) each own in
excess of 10% of the outstanding common stock of FRI and are the
principal stockholders of FRI. FRI, the Principal Shareholders and
each of the Investment Management Subsidiaries disclaim any
pecuniary interest in any of the shares. Franklin Advisors,
Inc. has sole voting and sole dispositive power with respect to the
shares. The principal address of Franklin Advisors, Inc., FRI
and the Principal Shareholders is One Franklin Parkway, San Mateo,
California 94403.
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No information found
* THE VALUE IS THE MARKET VALUE AS OF THE LAST DAY OF THE QUARTER FOR WHICH THE 13F WAS FILED.
| FUND | NUMBER OF SHARES | VALUE ($) | PUT OR CALL |
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| DIRECTORS | AGE | BIO | OTHER DIRECTOR MEMBERSHIPS |
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No information found
No Customers Found
No Suppliers Found
Price
Yield
| Owner | Position | Direct Shares | Indirect Shares |
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